117
Views
1
CrossRef citations to date
0
Altmetric
Drug Profile

Valsartan/amlodipine single pill combination for the treatment of hypertension

Pages 739-746 | Published online: 10 Jan 2014

References

  • Patricia M, Kearney PM, Whelton M et al. Global burden of hypertension: analysis of worldwide data. Lancet365, 217–223 (2005).
  • Chobanian AV, Bakris GL, Black HR et al; and the National High Blood Pressure Education Program Coordinating Committee. Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. JAMA289, 2560–2572 (2003).
  • Cutler JA, Sorlie PD, Wolz M, Thom T, Fields LE, Roccella EJ. Trends in hypertension prevalence, awareness, treatment, and control rates in United States adults between 1988–1994 and 1999–2004. Hypertension52, 818–827 (2008).
  • Wolf-Maier K, Cooper RS, Kramer H et al. Hypertension treatment and control in five European countries, Canada, and the United States. Hypertension43, 10–17 (2004).
  • Okonofua EC, Simpson KN, Jesri A, Rehman SU, Durkalski VL, Egan BM. Therapeutic inertia is an impediment to achieving the healthy people 2010 blood pressure control goals. Hypertension.47, 345–351 (2006).
  • Chapman RH, Benner JS, Petrilla AA et al. Predictors of adherence with antihypertensive and lipid-lowering therapy. Arch. Int. Med.165, 1147–1152 (2005).
  • Berg JS, Dischler J, Wagner DJ, Raia JJ, Palmer-Shevlin N. Medication compliance: a healthcare problem. Ann. Pharmacother.27(Suppl.), 1–24 (1993).
  • Métry J-M. Drug Regimen Compliance: Issues in Clinical Trials and Patient Management. John Wiley & Son Ltd, NJ, USA (1999).
  • Osterberg L, Blaschke T. Adherence to medication. N. Engl. J. Med.353, 487–497 (2005).
  • Dahlöf B, Sever PS, Poulter NR et al. ASCOT Investigators. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet366, 895–906 (2005).
  • Bakris GL. The importance of blood pressure control in the patient with diabetes. Am. J. Med.116, 30S–38S (2004).
  • The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). 2007 Guidelines for the Management of Arterial Hypertension. J. Hypertens.25, 1105–1187, 2007
  • Mancia G, Laurent S, Agabiti-Rosei E et al. Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document. J. Hypertens.27, 2121–2158 (2009).
  • Jamerson K, Weber MA, Bakris GL et al; for the ACCOMPLISH trial investigators. Benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients. N. Engl. J. Med.359, 2417–2428 (2008).
  • Hajjar ER, Cafiero AC, Hanlon JT. Polypharmacy in elderly patients. Am. J. Geriatr. Pharmacother.5, 345–351 (2007).
  • Dezii CM. A retrospective study of persistence with single-pill combination therapy vs concurrent two-pill therapy in patients with hypertension. Manag. Care9(Suppl.), 2–6 (2000).
  • Brixner DI, Jackson KC 2nd, Sheng X, Nelson RE, Keskinaslan A. Assessment of adherence, persistence, and costs among valsartan and hydrochlorothiazide retrospective cohorts in free-and fixed-dose combinations. Curr. Med. Res. Opin.24, 2597–607 (2008).
  • Blonde L, Wogen J, Kreilick C, Seymour AA. Greater reductions in A1C in Type 2 diabetic patients new to therapy with glyburide/metformin tablets as compared to glyburide co-administered with metformin. Diabetes Obes. Metab.5, 424–431 (2003).
  • Düsing R. Optimizing blood pressure control through the use of fixed combinations. Vasc. Health Risk Manag.6, 321–325 (2010).
  • Diovan (valsartan) tablets [prescribing information]. Novartis Pharmaceuticals Corporation, NJ, USA (2008).
  • Norvasc (amlodipine) tablets [prescribing information]. Pfizer Labs, Division of Pfizer Inc., NY, USA (2006).
  • Philipp T, Smith TR, Glazer R et al. Two multicenter, 8 week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension. Clin. Ther.29, 563–580 (2007).
  • Philipp T, Glazer RD, Zhao Y, Pospiech R. Long-term tolerability and efficacy of the combination of amlodipine/valsartan in hypertensive patients: a 54-week, open-label extension study. Curr. Med. Res. Opin.25, 187–193 (2009).
  • Smith TR, Philipp T, Vaisse B et al. Amlodipine and valsartan combined and as monotherapy in stage 2, elderly, and black hypertensive patients: subgroup analyses of 2 randomized, placebo-controlled studies. J. Clin. Hypertens. (Greenwich)5, 355–364 (2007).
  • Destro M, Luckow A, Samson M, Kandra A, Brunel P. Efficacy and safety of amlodipine/valsartan compared with amlodipine monotherapy in patients with stage 2 hypertension: a randomized, double-blind, multicenter study: the EX-EFFeCTS study. J. Am. Soc. Hypertens.2, 294–302 (2008).
  • Schunkert H, Glazer RD, Wernsing M et al. Efficacy and tolerability of amlodipine/valsartan combination therapy in hypertensive patients not adequately controlled on amlodipine monotherapy. Curr. Med. Res. Opin.25, 2655–2662 (2009).
  • Flack JM, Calhoun DA, Satlin L, Barbier M, Hilkert R, Brunel P. Efficacy and safety of initial combination therapy with amlodipine/valsartan compared with amlodipine monotherapy in black patients with stage 2 hypertension: the EX-STAND study. J. Hum. Hypertens.23, 479–489 (2009).
  • Alleman Y, Fraile B, Lambert M, Barbier M, Ferber P, Izzo JL Jr. Efficacy of the combination of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy: the Exforge in failure after single therapy (EX-FAST) study. J. Clin. Hypertens.10, 185–194 (2008).
  • Messerli FH, Oparil S, Feng Z. Comparison of efficacy and side effects of combination therapy of angiotensin-converting enzyme inhibitor (benazepril) with calcium antagonist (either nifedipine or amlodipine) versus high-dose calcium antagonist monotherapy for systemic hypertension. Am. J. Cardiol.86, 1182–1187 (2000).
  • Messerli FH. Vasodilatory edema: a common side effect of antihypertensive therapy. Curr. Cardiol. Rep.6, 479–482 (2002).
  • Fogari R, Zoppi A, Derosa G et al. Effect of valsartan addition to amlodipine on ankle oedema and subcutaneous tissue pressure in hypertensive patients. J. Hum. Hypertens.21, 220–224 (2007).
  • Frech-Tamas FH, Zhang W, Dastani HB, Gause D. Patient compliance with single pill, dual and triple antihypertensive combinations. Circulation120, 522 (2009) (Abstract).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.