Transfusion-related acute lung injury: advances in understanding the role of proinflammatory mediators in its genesis

References

• Barnard RD. Indiscriminate transfusion: a critique of case reports illustrating hypersensitivity reactions. NY State J. Med. 51(20), 2399–2402 (1951).
   PubMedGoogle Scholar
• Brittingham TE, Chaplin H Jr. Febrile transfusion reactions caused by sensitivity to donor leukocytes and platelets. J. Am. Med. Assoc. 165(7), 819–825 (1957).
   PubMed Web of Science ®Google Scholar
• Popovsky MA, Moore SB. Diagnostic and pathogenetic considerations in transfusion-related acute lung injury. Transfusion 25(6), 573–577 (1985).
   PubMed Web of Science ®Google Scholar
• Popovsky MA, Chaplin HC Jr, Moore SB. Transfusion-related acute lung injury: a neglected, serious complication of hemotherapy. Transfusion 32(6), 589–592 (1992).
   PubMed Web of Science ®Google Scholar
• de Vries RR, Faber JC, Strengers PF; Board of the International Haemovigilance Network. Haemovigilance: an effective tool for improving transfusion practice. Vox Sang. 100(1), 60–67 (2011).
   PubMed Web of Science ®Google Scholar
• Public Health Service (PHS) Biovigilance Task Group. Biovigilance in the United States: Efforts to Bridge a Critical Gap in Patient Safety and Donor Health. US Department of Health and Human Services, Washington, DC, USA (2009).
   Google Scholar
• Chapman CE, Stainsby D, Jones H et al.; Serious Hazards of Transfusion Steering Group. Ten years of hemovigilance reports of transfusion-related acute lung injury in the United Kingdom and the impact of preferential use of male donor plasma. Transfusion 49(3), 440–452 (2009).
   PubMed Web of Science ®Google Scholar
• Hendrickson JE, Hillyer CD. Noninfectious serious hazards of transfusion. Anesth. Analg. 108(3), 759–769 (2009).
   PubMed Web of Science ®Google Scholar
• Eder AF, Herron RM Jr, Strupp A et al. Effective reduction of transfusion-related acute lung injury risk with male-predominant plasma strategy in the American Red Cross (2006–2008). Transfusion 50(8), 1732–1742 (2010).
   PubMed Web of Science ®Google Scholar
• Eder AF, Dy BA, Perez JM, Rambaud M, Benjamin RJ. The residual risk of transfusion-related acute lung injury at the American Red Cross (2008–2011): limitations of a predominantly male-donor plasma mitigation strategy. Transfusion doi:10.1111/j.1537-2995.2012.03935.x (2012) (Epub ahead of print).
   Google Scholar
• Holness L, Knippen MA, Simmons L, Lachenbruch PA. Fatalities caused by TRALI. Transfus. Med. Rev. 18(3), 184–188 (2004).
   PubMed Web of Science ®Google Scholar
• Toy P, Popovsky MA, Abraham E et al.; National Heart, Lung and Blood Institute Working Group on TRALI. Transfusion-related acute lung injury: definition and review. Crit. Care Med. 33(4), 721–726 (2005).
   PubMed Web of Science ®Google Scholar
• Eder AF, Herron R, Strupp A et al. Transfusion-related acute lung injury surveillance (2003–2005) and the potential impact of the selective use of plasma from male donors in the American Red Cross. Transfusion 47(4), 599–607 (2007).
   PubMed Web of Science ®Google Scholar
• US Food and Drug Administration. Fatalities Reported to FDA Following Blood Collection and Transfusion: Annual Summary for Fiscal Year 2011. US Food and Drug Administration, Silver Spring, MD, USA (2012).
   Google Scholar
• Popovsky MA. Transfusion related acute lung injury. In: Transfusion Reactions (2nd Edition). AABB Press, MD, USA, 155–170 (2001).
   Google Scholar
• Renaudier PC, Vo Mai MP, Azanowsky JM et al. Epidemiology of transfusion related acute lung injury in Gifit, the Frech Hemovigilance Database. a study of the French Hemovigilance Network. Transfusion 44(Suppl. 9), 23A (2004).
   Google Scholar
• Silliman CC, Paterson AJ, Dickey WO et al. The association of biologically active lipids with the development of transfusion-related acute lung injury: a retrospective study. Transfusion 37(7), 719–726 (1997).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Boshkov LK, Mehdizadehkashi Z et al. Transfusion-related acute lung injury: epidemiology and a prospective analysis of etiologic factors. Blood 101(2), 454–462 (2003).
   PubMed Web of Science ®Google Scholar
• Wallis JP, Lubenko A, Wells AW, Chapman CE. Single hospital experience of TRALI. Transfusion 43(8), 1053–1059 (2003).
   PubMed Web of Science ®Google Scholar
• Looney MR, Gropper MA, Matthay MA. Transfusion-related acute lung injury: a review. Chest 126(1), 249–258 (2004).
   PubMed Web of Science ®Google Scholar
• Middelburg RA, van Stein D, Briët E, van der Bom JG. The role of donor antibodies in the pathogenesis of transfusion-related acute lung injury: a systematic review. Transfusion 48(10), 2167–2176 (2008).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Fung YL, Ball JB, Khan SY. Transfusion-related acute lung injury (TRALI): current concepts and misconceptions. Blood Rev. 23(6), 245–255 (2009).
   PubMed Web of Science ®Google Scholar
• Vlaar AP. Transfusion-related acute lung injury: current understanding and preventive strategies. Transfus. Clin. Biol. 19(3), 117–124 (2012).
   PubMed Web of Science ®Google Scholar
• Benson AB, Austin GL, Berg M et al. Transfusion-related acute lung injury in ICU patients admitted with gastrointestinal bleeding. Intensive Care Med. 36(10), 1710–1717 (2010).
   PubMed Web of Science ®Google Scholar
• Clifford L, Singh A, Wilson GA et al. Electronic health record surveillance algorithms facilitate the detection of transfusion-related pulmonary complications. Transfusion doi:10.1111/j.1537-2995.2012.03886.x (2012) (Epub ahead of print).
   PubMedGoogle Scholar
• Silliman CC. Transfusion-related acute lung injury. Transfus. Med. Rev. 13(3), 177–186 (1999).
   PubMed Web of Science ®Google Scholar
• Cruz J, Skipworth E, Blue D, Waxman D, McCarthy L, Smith D. Transfusion-related acute lung injury: a thrombotic thrombocytopenic purpura treatment-associated case report and concise review. J. Clin. Apher. 23(2), 96–103 (2008).
   PubMed Web of Science ®Google Scholar
• P’ng SS, Hughes AS, Cooney JP. A case report of transfusion-related acute lung injury during plasma exchange therapy for thrombotic thrombocytopenia purpura. Ther. Apher. Dial. 12(1), 78–81 (2008).
   PubMed Web of Science ®Google Scholar
• Gajic O, Yilmaz M, Iscimen R et al. Transfusion from male-only versus female donors in critically ill recipients of high plasma volume components. Crit. Care Med. 35(7), 1645–1648 (2007).
   PubMed Web of Science ®Google Scholar
• Toy P, Gajic O, Bacchetti P et al.; TRALI Study Group. Transfusion-related acute lung injury: incidence and risk factors. Blood 119(7), 1757–1767 (2012).
   PubMed Web of Science ®Google Scholar
• Kleinman S, Caulfield T, Chan P et al. Toward an understanding of transfusion-related acute lung injury: statement of a consensus panel. Transfusion 44(12), 1774–1789 (2004).
   PubMed Web of Science ®Google Scholar
• Bux J, Sachs UJ. The pathogenesis of transfusion-related acute lung injury (TRALI). Br. J. Haematol. 136(6), 788–799 (2007).
   PubMed Web of Science ®Google Scholar
• Bux J. Antibody-mediated (immune) transfusion-related acute lung injury. Vox Sang. 100(1), 122–128 (2011).
   PubMed Web of Science ®Google Scholar
• Sachs UJ. The pathogenesis of transfusion-related acute lung injury and how to avoid this serious adverse reaction of transfusion. Transfus. Apher. Sci. 37(3), 273–282 (2007).
   PubMed Web of Science ®Google Scholar
• Bernard GR, Artigas A, Brigham KL et al. Report of the American-European Consensus conference on acute respiratory distress syndrome: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Consensus Committee. J. Crit. Care 9(1), 72–81 (1994).
   PubMed Web of Science ®Google Scholar
• Kuroda H, Masuda Y, Imaizumi H, Kozuka Y, Asai Y, Namiki A. Successful extracorporeal membranous oxygenation for a patient with life-threatening transfusion-related acute lung injury. J. Anesth. 23(3), 424–426 (2009).
   PubMed Web of Science ®Google Scholar
• Lee AJ, Koyyalamudi PL, Martinez-Ruiz R. Severe transfusion-related acute lung injury managed with extracorporeal membrane oxygenation (ECMO) in an obstetric patient. J. Clin. Anesth. 20(7), 549–552 (2008).
   PubMed Web of Science ®Google Scholar
• Fung YL, Silliman CC. The role of neutrophils in the pathogenesis of transfusion-related acute lung injury. Transfus. Med. Rev. 23(4), 266–283 (2009).
   PubMed Web of Science ®Google Scholar
• Albelda SM, Smith CW, Ward PA. Adhesion molecules and inflammatory injury. FASEB J. 8(8), 504–512 (1994).
   PubMed Web of Science ®Google Scholar
• Carlos TM, Harlan JM. Leukocyte–endothelial adhesion molecules. Blood 84(7), 2068–2101 (1994).
   PubMed Web of Science ®Google Scholar
• Silliman CC. The two-event model of transfusion-related acute lung injury. Crit. Care Med. 34(Suppl. 5), S124–S131 (2006).
   PubMed Web of Science ®Google Scholar
• Kopko PM, Popovsky MA, MacKenzie MR, Paglieroni TG, Muto KN, Holland PV. HLA class II antibodies in transfusion-related acute lung injury. Transfusion 41(10), 1244–1248 (2001).
   PubMed Web of Science ®Google Scholar
• American Association of Blood Banks. AABB Standards for Blood Banks and Transfusion Services (27th Edition). American Association of Blood Banks, MD, USA (2011).
   Google Scholar
• Vlaar AP, Kulik W, Nieuwland R et al. Accumulation of bioactive lipids during storage of blood products is not cell but plasma derived and temperature dependent. Transfusion 51(11), 2358–2366 (2011).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Kelher M, Ambruso DR. Bioactive lipids from stored cellular blood components: in vitro method is crucial for proper interpretation. Transfusion 52(5), 1155–1157; author reply 1157 (2012).
   PubMed Web of Science ®Google Scholar
• Tissot JD, Rubin O, Canellini G. Analysis and clinical relevance of microparticles from red blood cells. Curr. Opin. Hematol. 17(6), 571–577 (2010).
   PubMed Web of Science ®Google Scholar
• Cardo LJ, Wilder D, Salata J. Neutrophil priming, caused by cell membranes and microvesicles in packed red blood cell units, is abrogated by leukocyte depletion at collection. Transfus. Apher. Sci. 38(2), 117–125 (2008).
   PubMed Web of Science ®Google Scholar
• Simak J, Gelderman MP. Cell membrane microparticles in blood and blood products: potentially pathogenic agents and diagnostic markers. Transfus. Med. Rev. 20(1), 1–26 (2006).
   PubMed Web of Science ®Google Scholar
• Stapley R, Owusu BY, Brandon A et al. Erythrocyte storage increases rates of NO and nitrite scavenging: implications for transfusion-related toxicity. Biochem. J. 446(3), 499–508 (2012).
   PubMed Web of Science ®Google Scholar
• Kent MW, Kelher MR, Le T, Silliman CC. Microparticles: role in packed red blood cell (PRBC) units. Blood 120(20), 1178 (2012).
   Google Scholar
• Bercovitz RS, Kelher MR, Khan SY, Land KJ, Berry TH, Silliman CC. The pro-inflammatory effects of platelet contamination in plasma and mitigation strategies for avoidance. Vox Sang. 102(4), 345–353 (2012).
   PubMed Web of Science ®Google Scholar
• Tuinman PR, Gerards MC, Jongsma G, Vlaar AP, Boon L, Juffermans NP. Lack of evidence of CD40 ligand involvement in transfusion-related acute lung injury. Clin. Exp. Immunol. 165(2), 278–284 (2011).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Voelkel NF, Allard JD et al. Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model. J. Clin. Invest. 101(7), 1458–1467 (1998).
   PubMed Web of Science ®Google Scholar
• Van Buren NL, Stroncek DF, Clay ME, McCullough J, Dalmasso AP. Transfusion-related acute lung injury caused by an NB2 granulocyte-specific antibody in a patient with thrombotic thrombocytopenic purpura. Transfusion 30(1), 42–45 (1990).
   PubMed Web of Science ®Google Scholar
• Wyman TH, Bjornsen AJ, Elzi DJ et al. A two-insult in vitro model of PMN-mediated pulmonary endothelial damage: requirements for adherence and chemokine release. Am. J. Physiol. Cell Physiol. 283(6), C1592–C1603 (2002).
   PubMed Web of Science ®Google Scholar
• Kopko PM, Marshall CS, MacKenzie MR, Holland PV, Popovsky MA. Transfusion-related acute lung injury: report of a clinical look-back investigation. JAMA 287(15), 1968–1971 (2002).
   PubMed Web of Science ®Google Scholar
• Toy P, Hollis-Perry KM, Jun J, Nakagawa M. Recipients of blood from a donor with multiple HLA antibodies: a lookback study of transfusion-related acute lung injury. Transfusion 44(12), 1683–1688 (2004).
   PubMed Web of Science ®Google Scholar
• Hashimoto S, Nakajima F, Kamada H et al. Relationship of donor HLA antibody strength to the development of transfusion-related acute lung injury. Transfusion 50(12), 2582–2591 (2010).
   PubMed Web of Science ®Google Scholar
• Saw CL, Hannach B, Petrazsko T, Nickerson P. Blood donors implicated in transfusion-related acute lung injury with patient-specific HLA antibodies are more broadly sensitized to HLA antigens compared to other blood donors. Transfusion 53(3), 518–525 (2013).
   PubMed Web of Science ®Google Scholar
• Fung YL, Kim M, Tabuchi A et al. Recipient T lymphocytes modulate the severity of antibody-mediated transfusion-related acute lung injury. Blood 116(16), 3073–3079 (2010).
   PubMed Web of Science ®Google Scholar
• Vlaar AP, Kuipers MT, Hofstra JJ et al. Mechanical ventilation and the titer of antibodies as risk factors for the development of transfusion-related lung injury. Crit. Care Res. Pract. 2012, 720950 (2012).
   PubMedGoogle Scholar
• Rabinovici R, Bugelski PJ, Esser KM, Hillegass LM, Vernick J, Feuerstein G. ARDS-like lung injury produced by endotoxin in platelet-activating factor-primed rats. J. Appl. Physiol. 74(4), 1791–1802 (1993).
   PubMed Web of Science ®Google Scholar
• Salzer WL, McCall CE. Primed stimulation of isolated perfused rabbit lung by endotoxin and platelet activating factor induces enhanced production of thromboxane and lung injury. J. Clin. Invest. 85(4), 1135–1143 (1990).
   PubMed Web of Science ®Google Scholar
• Kelher MR, Masuno T, Moore EE et al. Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model. Blood 113(9), 2079–2087 (2009).
   PubMed Web of Science ®Google Scholar
• Khan SY, Kelher MR, Heal JM et al. Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury. Blood 108(7), 2455–2462 (2006).
   PubMed Web of Science ®Google Scholar
• Looney MR, Su X, Van Ziffle JA, Lowell CA, Matthay MA. Neutrophils and their Fc γ receptors are essential in a mouse model of transfusion-related acute lung injury. J. Clin. Invest. 116(6), 1615–1623 (2006).
   PubMed Web of Science ®Google Scholar
• Sachs UJ, Hattar K, Weissmann N et al. Antibody-induced neutrophil activation as a trigger for transfusion-related acute lung injury in an ex vivo rat lung model. Blood 107(3), 1217–1219 (2006).
   PubMed Web of Science ®Google Scholar
• Sachs UJ, Wasel W, Reil A et al. Mechanism of transfusion-related acute lung injury induced by HLA class II antibodies. Blood 114(22), 14 (2009).
   Google Scholar
• Silliman CC, Moore EE, Kelher MR, Khan SY, Gellar L, Elzi DJ. Identification of lipids that accumulate during the routine storage of prestorage leukoreduced red blood cells and cause acute lung injury. Transfusion 51(12), 2549–2554 (2011).
   PubMed Web of Science ®Google Scholar
• Sachs UJ. A threshold model for the susceptibility to transfusion-related acute lung injury. Transfus. Clin. Biol. 19(3), 109–116 (2012).
   PubMed Web of Science ®Google Scholar
• Gans RO, Duurkens VA, van Zundert AA, Hoorntje SJ. Transfusion-related acute lung injury. Intensive Care Med. 14(6), 654–657 (1988).
   PubMed Web of Science ®Google Scholar
• Yomtovian R, Kline W, Press C et al. Severe pulmonary hypersensitivity associated with passive transfusion of a neutrophil-specific antibody. Lancet 1(8371), 244–246 (1984).
   PubMed Web of Science ®Google Scholar
• Dooren MC, Ouwehand WH, Verhoeven AJ, von dem Borne AE, Kuijpers RW. Adult respiratory distress syndrome after experimental intravenous γ-globulin concentrate and monocyte-reactive IgG antibodies. Lancet 352(9140), 1601–1602 (1998).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Ambruso DR, Boshkov LK. Transfusion-related acute lung injury. Blood 105(6), 2266–2273 (2005).
   PubMed Web of Science ®Google Scholar
• Hidalgo A, Chang J, Jang JE, Peired AJ, Chiang EY, Frenette PS. Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury. Nat. Med. 15(4), 384–391 (2009).
   PubMed Web of Science ®Google Scholar
• Dykes A, Smallwood D, Kotsimbos T, Street A. Transfusion-related acute lung injury (TRALI) in a patient with a single lung transplant. Br. J. Haematol. 109(3), 674–676 (2000).
   PubMed Web of Science ®Google Scholar
• Seeger W, Schneider U, Kreusler B et al. Reproduction of transfusion-related acute lung injury in an ex vivo lung model. Blood 76(7), 1438–1444 (1990).
   PubMed Web of Science ®Google Scholar
• Partrick DA, Moore EE, Fullerton DA, Barnett CC Jr, Meldrum DR, Silliman CC. Cardiopulmonary bypass renders patients at risk for multiple organ failure via early neutrophil priming and late neutrophil disability. J. Surg. Res. 86(1), 42–49 (1999).
   PubMed Web of Science ®Google Scholar
• Ward RA, McLeish KR. Hemodialysis with cellulose membranes primes the neutrophil oxidative burst. Artif. Organs 19(8), 801–807 (1995).
   PubMed Web of Science ®Google Scholar
• Worthen GS, Schwab B 3rd, Elson EL, Downey GP. Mechanics of stimulated neutrophils: cell stiffening induces retention in capillaries. Science 245(4914), 183–186 (1989).
   PubMed Web of Science ®Google Scholar
• Klein JB, McLeish KR, Ward RA. Transplantation, not dialysis, corrects azotemia-dependent priming of the neutrophil oxidative burst. Am. J. Kidney Dis. 33(3), 483–491 (1999).
   PubMed Web of Science ®Google Scholar
• Körmöczi GF, Rosenkranz AR, Zlabinger GJ. Polymorphonuclear granulocyte stimulation by cellulose-based hemodialysis membranes. Clin. Chem. Lab. Med. 37(3), 351–355 (1999).
   PubMed Web of Science ®Google Scholar
• Wallis JP, Haynes S, Stark G, Green FA, Lucas GF, Chapman CE. Transfusion-related alloimmune neutropenia: an undescribed complication of blood transfusion. Lancet 360(9339), 1073–1074 (2002).
   PubMed Web of Science ®Google Scholar
• Varela M, Mas A, Nogués N, Escorsell A, Mazzara R, Lozano M. TRALI associated with HLA class II antibodies. Transfusion 42(8), 1102 (2002).
   PubMed Web of Science ®Google Scholar
• Win N, Brown C, Navarrete C. TRALI associated with HLA class II antibodies. Transfusion 43(4), 545–546 (2003).
   PubMedGoogle Scholar
• Gajic O, Rana R, Winters JL et al. Transfusion related acute lung injury in the critically Ill: prospective nested case–control study. Am. J. Respir. Crit Care Med. 176(9), 886–891 (2007).
   PubMed Web of Science ®Google Scholar
• Kopko PM, Paglieroni TG, Popovsky MA, Muto KN, MacKenzie MR, Holland PV. TRALI: correlation of antigen–antibody and monocyte activation in donor–recipient pairs. Transfusion 43(2), 177–184 (2003).
   PubMed Web of Science ®Google Scholar
• Kelher MR, Silliman CC. Antibodies specific for MHC class II antigens cause TRALI directly in a two-event in vivo model. Blood 120, 845 (2012).
   Google Scholar
• Wang D, Sun J, Solomon SB, Klein HG, Natanson C. Transfusion of older stored blood and risk of death: a meta-analysis. Transfusion 52(6), 1184–1195 (2012).
   PubMed Web of Science ®Google Scholar
• van de Watering L. Pitfalls in the current published observational literature on the effects of red blood cell storage. Transfusion 51(8), 1847–1854 (2011).
   PubMed Web of Science ®Google Scholar
• van de Watering L, Lorinser J, Versteegh M, Westendord R, Brand A. Effects of storage time of red blood cell transfusions on the prognosis of coronary artery bypass graft patients. Transfusion 46(10), 1712–1718 (2006).
   PubMed Web of Science ®Google Scholar
• Kor DJ, Kashyap R, Weiskopf RB et al. Fresh red blood cell transfusion and short-term pulmonary, immunologic, and coagulation status: a randomized clinical trial. Am. J. Respir. Crit. Care Med. 185(8), 842–850 (2012).
   PubMed Web of Science ®Google Scholar
• Middelburg RA, Borkent-Raven BA, Borkent B et al. Storage time of blood products and transfusion-related acute lung injury. Transfusion 52(3), 658–667 (2012).
   PubMed Web of Science ®Google Scholar
• Vlaar AP, Hofstra JJ, Kulik W et al. Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model. Blood 116(8), 1360–1368 (2010).
   PubMed Web of Science ®Google Scholar
• Vlaar AP, Binnekade JM, Prins D et al. Risk factors and outcome of transfusion-related acute lung injury in the critically ill: a nested case–control study. Crit. Care Med. 38(3), 771–778 (2010).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Dickey WO, Paterson AJ et al. Analysis of the priming activity of lipids generated during routine storage of platelet concentrates. Transfusion 36(2), 133–139 (1996).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Clay KL, Thurman GW, Johnson CA, Ambruso DR. Partial characterization of lipids that develop during the routine storage of blood and prime the neutrophil NADPH oxidase. J. Lab. Clin. Med. 124(5), 684–694 (1994).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Khan SY, Ball JB, Kelher MR, Marschner S. Mirasol pathogen reduction technology treatment does not affect acute lung injury in a two-event in vivo model caused by stored blood components. Vox Sang. 98(4), 525–530 (2010).
   PubMed Web of Science ®Google Scholar
• Dzieciatkowska M, Silliman CC, Moore EE et al. Proteomic analysis of the supernatant of red blood cell units: the effects of storage and leukoreduction. Vox Sang. (2013) (In Press).
   PubMedGoogle Scholar
• Khan SY, McLaughlin NJ, Kelher MR et al. Lysophosphatidylcholines activate G2A inducing G(αi)-/G(αq/)- Ca(2)(+) flux, G(βγ)-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs. Biochem. J. 432(1), 35–45 (2010).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Bjornsen AJ, Wyman TH et al. Plasma and lipids from stored platelets cause acute lung injury in an animal model. Transfusion 43(5), 633–640 (2003).
   PubMed Web of Science ®Google Scholar
• Looney MR, Nguyen JX, Hu Y, Van Ziffle JA, Lowell CA, Matthay MA. Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. J. Clin. Invest. 119(11), 3450–3461 (2009).
   PubMed Web of Science ®Google Scholar
• Bayat B, Tjahjono Y, Akylbek S et al. Lung endothelial injury induced by HNA-3a antibodies in TRALI. Blood 120(20), 22 (2012).
   Google Scholar
• Vlaar AP, Hofstra JJ, Determann RM et al. Transfusion-related acute lung injury in cardiac surgery patients is characterized by pulmonary inflammation and coagulopathy: a prospective nested case–control study. Crit. Care Med. 40(10), 2813–2820 (2012).
   PubMed Web of Science ®Google Scholar
• Covin RB, Ambruso DR, England KM et al. Hypotension and acute pulmonary insufficiency following transfusion of autologous red blood cells during surgery: a case report and review of the literature. Transfus. Med. 14(5), 375–383 (2004).
   PubMed Web of Science ®Google Scholar
• Tuinman PR, Schultz MJ, Juffermans NP. Coagulopathy as a therapeutic target for TRALI: rationale and possible sites of action. Curr. Pharm. Des. 18(22), 3267–3272 (2012).
   PubMed Web of Science ®Google Scholar
• Vlaar AP, Hofstra JJ, Levi M et al. Supernatant of aged erythrocytes causes lung inflammation and coagulopathy in a ‘two-hit’ in vivo syngeneic transfusion model. Anesthesiology 113(1), 92–103 (2010).
   PubMed Web of Science ®Google Scholar
• Blumberg N, Heal JM, Gettings KF et al. An association between decreased cardiopulmonary complications (transfusion-related acute lung injury and transfusion-associated circulatory overload) and implementation of universal leukoreduction of blood transfusions. Transfusion 50(12), 2738–2744 (2010).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Moore EE, Johnson JL, Gonzalez RJ, Biffl WL. Transfusion of the injured patient: proceed with caution. Shock 21(4), 291–299 (2004).
   PubMed Web of Science ®Google Scholar
• Insunza A, Romon I, Gonzalez-Ponte ML et al. Implementation of a strategy to prevent TRALI in a regional blood centre. Transfus. Med. 14(2), 157–164 (2004).
   PubMed Web of Science ®Google Scholar
• Endres RO, Kleinman SH, Carrick DM et al.; National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Study-II. Identification of specificities of antibodies against human leukocyte antigens in blood donors. Transfusion 50(8), 1749–1760 (2010).
   PubMed Web of Science ®Google Scholar
• Kleinman SH, Triulzi DJ, Murphy EL et al.; National Heart, Lung, and Blood Institute Retrovirus Epidemiology Donor Study-II. The Leukocyte Antibody Prevalence Study-II (LAPS-II): a retrospective cohort study of transfusion-related acute lung injury in recipients of high-plasma-volume human leukocyte antigen antibody-positive or -negative components. Transfusion 51(10), 2078–2091 (2011).
   PubMed Web of Science ®Google Scholar
• Curtis BR. Future preventive and therapeutic targets for transfusion-related acute lung injury. Curr. Pharm. Des. 18(22), 3285–3292 (2012).
   PubMed Web of Science ®Google Scholar
• Makar RS, Powers A, Stowell CP. Reducing transfusion-related acute lung injury risk: evidence for and approaches to transfusion-related acute lung injury mitigation. Transfus. Med. Rev. 26(4), 305–320 (2012).
   PubMed Web of Science ®Google Scholar
• Gilliss BM, Looney MR, Gropper MA. Reducing noninfectious risks of blood transfusion. Anesthesiology 115(3), 635–649 (2011).
   PubMed Web of Science ®Google Scholar
• Middelburg RA, Van Stein D, Zupanska B et al. Female donors and transfusion-related acute lung injury: a case-referent study from the International TRALI Unisex Research Group. Transfusion 50(11), 2447–2454 (2010).
   PubMed Web of Science ®Google Scholar
• Hellstern P, Solheim BG. The use of solvent/detergent treatment in pathogen reduction of plasma. Transfus. Med. Hemother. 38(1), 65–70 (2011).
   PubMed Web of Science ®Google Scholar
• Fuggle SV, Martin S. Tools for human leukocyte antigen antibody detection and their application to transplanting sensitized patients. Transplantation 86(3), 384–390 (2008).
   PubMed Web of Science ®Google Scholar
• Zeevi A, Girnita A, Duquesnoy R. HLA antibody analysis: sensitivity, specificity, and clinical significance in solid organ transplantation. Immunol. Res. 36(1–3), 255–264 (2006).
   PubMed Web of Science ®Google Scholar
• Bierling P, Bux J, Curtis B et al. Recommendations of the ISBT Working Party on Granulocyte Immunobiology for leucocyte antibody screening in the investigation and prevention of antibody-mediated transfusion-related acute lung injury. Vox Sang. 96(3), 266–269 (2009).
   PubMed Web of Science ®Google Scholar
• Sachs UJ, Bux J. TRALI after the transfusion of cross-match-positive granulocytes. Transfusion 43(12), 1683–1686 (2003).
   PubMed Web of Science ®Google Scholar
• Bux J. Challenges in the determination of clinically significant granulocyte antibodies and antigens. Transfus. Med. Rev. 10(3), 222–232 (1996).
   PubMed Web of Science ®Google Scholar
• Fung YL, Goodison KA, Wong JK, Minchinton RM. Investigating transfusion-related acute lung injury (TRALI). Intern. Med. J. 33(7), 286–290 (2003).
   PubMed Web of Science ®Google Scholar
• Schmidt EP, Yang Y, Janssen WJ et al. The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Nat. Med. doi:10.1038/nm.2843 (2012) (Epub ahead of print).
   Google Scholar
• Giarratana MC, Rouard H, Dumont A et al. Proof of principle for transfusion of in vitro-generated red blood cells. Blood 118(19), 5071–5079 (2011).
   PubMed Web of Science ®Google Scholar
• Silliman CC, Kelher MR, Khan SY, Sowemimo-Coker SO. Experimental antibody filtration inhibits antibody-mediated neutrophil priming and TRALI in an in vivo model. Blood 118(21), 22 (2011).
   Google Scholar