Interspecies bacterial communication as a target for therapy in otitis media

References

• Costerton JW, Cheng KJ, Geesey GG et al. Bacterial biofilms in nature and disease. Annu. Rev. Microbiol.41(1), 435–464 (1987).
   PubMed Web of Science ®Google Scholar
• Hendolin PH, Markkanen A, Ylikoski J, Wahlfors JJ. Use of multiplex PCR for simultaneous detection of four bacterial species in middle ear effusions. J. Clin. Microbiol.35(11), 2854–2858 (1997).
   PubMed Web of Science ®Google Scholar
• Maddocks JL, May JR. ‘Indirect pathogenicity’ of penicillinase-producing enterobacteria in chronic bronchial infections. Lancet1(7599), 793–795 (1969).
   PubMed Web of Science ®Google Scholar
• Armbruster CE, Hong W, Pang B et al. Indirect pathogenicity of Haemophilus influenzae and Moraxella catarrhalis in polymicrobial otitis media occurs via interspecies quorum signaling. MBio1(3), e00102–e00110 (2010).
   PubMed Web of Science ®Google Scholar
• Finkelstein JA, Davis RL, Dowell SF et al. Reducing antibiotic use in children: a randomized trial in 12 practices. Pediatrics108(1), 1–7 (2001).
   PubMed Web of Science ®Google Scholar
• Rayner MG, Zhang Y, Gorry MC, Chen Y, Post JC, Ehrlich GD. Evidence of bacterial metabolic activity in culture-negative otitis media with effusion. JAMA279(4), 296–299 (1998).
   PubMed Web of Science ®Google Scholar
• Wardle JK. Branhamella catarrhalis as an indirect pathogen. Drugs31(Suppl. 3), 93–96 (1986).
   PubMedGoogle Scholar
• Brook I. Direct and indirect pathogenicity of Branhamella catarrhalis. Drugs31(Suppl. 3), 97–102 (1986).
   PubMedGoogle Scholar
• Maddocks JL. Indirect pathogenicity. J. Antimicrob. Chemother.6(3), 307–309 (1980).
   PubMedGoogle Scholar
• Hol C, Van Dijke EE, Verduin CM, Verhoef J, van Dijk H. Experimental evidence for Moraxella-induced penicillin neutralization in pneumococcal pneumonia. J. Infect. Dis.170(6), 1613–1616 (1994).
   PubMed Web of Science ®Google Scholar
• Budhani RK, Struthers JK. Interaction of Streptococcus pneumoniae and Moraxella catarrhalis: investigation of the indirect pathogenic role of β-lactamase-producing moraxellae by use of a continuous-culture biofilm system. Antimicrob. Agents Chemother.42(10), 2521–2526 (1998).
   PubMed Web of Science ®Google Scholar
• Pichichero ME. Recurrent and persistent otitis media. Pediatr. Infect. Dis. J.19(9), 911–916 (2000).
   PubMed Web of Science ®Google Scholar
• St Geme JW. Molecular and cellular determinants of non-typeable Haemophilus influenzae adherence and invasion. Cell Microbiol.4(4), 191–200 (2002).
   PubMedGoogle Scholar
• Grevers G. Challenges in reducing the burden of otitis media disease: an ENT perspective on improving management and prospects for prevention. Int. J. Pediatr. Otorhinolaryngol.74(6), 572–577 (2010).
   PubMedGoogle Scholar
• Costerton JW, Stewart PS, Greenberg EP. Bacterial biofilms: a common cause of persistent infections. Science284, 1318–1322 (1999).
   PubMed Web of Science ®Google Scholar
• Bakaletz LO. Bacterial biofilms in otitis media: evidence and relevance. Pediatr. Infect. Dis. J.26(10 Suppl.), S17–S19 (2007).
   PubMed Web of Science ®Google Scholar
• Post JC, Hiller NL, Nistico L, Stoodley P, Ehrlich GD. The role of biofilms in otolaryngologic infections: update 2007. Curr. Opin. Otolaryngol. Head Neck Surg.15(5), 347–351 (2007).
   PubMedGoogle Scholar
• Weimer KED, Armbruster CE, Juneau RA, Hong W, Pang B, Swords WE. Coinfection with Haemophilus influenzae promotes pneumococcal biofilm formation during experimental otitis media and impedes the progression of pneumococcal disease. J. Infect. Dis.202(7), 1068–1075 (2010).
   PubMed Web of Science ®Google Scholar
• Grijalva CG, Nuorti JP, Griffin MR. Antibiotic prescription rates for acute respiratory tract infections in US ambulatory settings. JAMA302(7), 758–766 (2009).
   PubMed Web of Science ®Google Scholar
• Grubb MS, Spaugh DC. Treatment failure, recurrence, and antibiotic prescription rates for different acute otitis media treatment methods. Clin. Pediatr. (Phila). DOI: 10.1177/0009922810370363 (2010) (Epub ahead of print).
   Google Scholar
• Dagan R, Leibovitz E. Bacterial eradication in the treatment of otitis media. Lancet Infect. Dis.2(10), 593–604 (2002).
   PubMed Web of Science ®Google Scholar
• Pelton SIMD, Leibovitz EMD. Recent advances in otitis media. Pediatric Infectious Disease Journal28(10) Supplement, Childhood respiratory (diseases), management in an era of antibiotic resistance: S133–S137 (2009).
   Google Scholar
• Williams RL, Chalmers TC, Stange KC, Chalmers FT, Bowlin SJ. Use of antibiotics in preventing recurrent acute otitis media and in treating otitis media with effusion. A meta-analytic attempt to resolve the brouhaha. JAMA270(11), 1344–1351 (1993).
   PubMed Web of Science ®Google Scholar
• Anderson GG, O’Toole GA. Innate and induced resistance mechanisms of bacterial biofilms. Curr. Top. Microbiol. Immunol.322, 85–105 (2008).
   PubMed Web of Science ®Google Scholar
• Schuerman L, Borys D, Hoet B, Forsgren A, Prymula R. Prevention of otitis media: now a reality? Vaccine27(42), 5748–5754 (2009).
   PubMed Web of Science ®Google Scholar
• Eskola J, Kilpi T, Palmu A et al. Efficacy of a pneumococcal conjugate vaccine against acute otitis media. N. Engl. J. Med.344(6), 403–409 (2001).
   PubMed Web of Science ®Google Scholar
• Hardie KR, Heurlier K. Establishing bacterial communities by ‘word of mouth’: LuxS and autoinducer 2 in biofilm development. Nat. Rev. Microbiol.6(8), 635–643 (2008).
   PubMed Web of Science ®Google Scholar
• Jayaraman A, Wood TK. Bacterial quorum sensing: signals, circuits, and implications for biofilms and disease. Annu. Rev. Biomed. Eng.10, 145–167 (2008).
   PubMed Web of Science ®Google Scholar
• Miller MB, Bassler BL. Quorum sensing in bacteria. Annu. Rev. Microbiol.55, 165–199 (2001).
   PubMed Web of Science ®Google Scholar
• Waters CM, Bassler BL. Quorum sensing: cell-to-cell communication in bacteria. Annu. Rev. Cell Dev. Biol.21, 319–346 (2005).
   PubMed Web of Science ®Google Scholar
• Ng WL, Bassler BL. Bacterial quorum-sensing network architectures. Annu. Rev. Genet.43, 197–222 (2009).
   PubMed Web of Science ®Google Scholar
• Njoroge J, Sperandio V. Jamming bacterial communication: new approaches for the treatment of infectious diseases. EMBO Mol. Med.1(4), 201–210 (2009).
   PubMed Web of Science ®Google Scholar
• Landini P, Antoniani D, Burgess JG, Nijland R. Molecular mechanisms of compounds affecting bacterial biofilm formation and dispersal. Appl. Microbiol. Biotechnol.86(3), 813–823 (2010).
   PubMed Web of Science ®Google Scholar
• Alexander HR, Robert JP Jr, David SB et al. Autoinducer 2: a concentration-dependent signal for mutualistic bacterial biofilm growth. Mol. Microbiol.60(6), 1446–1456 (2006).
   PubMedGoogle Scholar
• Rickard AH, Campagna SR, Kolenbrander PE. Autoinducer-2 is produced in saliva-fed flow conditions relevant to natural oral biofilms. J. Appl. Microbiol.105(6), 2096–2103 (2008).
   PubMed Web of Science ®Google Scholar
• Armbruster CE, Hong W, Pang B et al. LuxS promotes biofilm maturation and persistence of nontypeable Haemophilus influenzaein vivo via modulation of lipooligosaccharides on the bacterial surface. Infect. Immun.77(9), 4081–4091 (2009).
   PubMed Web of Science ®Google Scholar
• Daines DA, Bothwell M, Furrer J et al.Haemophilus influenzae luxS mutants form a biofilm and have increased virulence. Microb. Pathog.39(3), 87–96 (2005).
   PubMed Web of Science ®Google Scholar
• Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infect. Immun.72(5), 2964–2975 (2004).
   PubMedGoogle Scholar
• Stroeher UH, Paton AW, Ogunniyi AD, Paton JC. Mutation of luxS of Streptococcus pneumoniae affects virulence in a mouse model. Infect. Immun.71(6), 3206–3212 (2003).
   PubMedGoogle Scholar
• Bassler BL, Wright M, Silverman MR. Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway. Mol. Microbiol.13(2), 273–286 (1994).
   PubMed Web of Science ®Google Scholar
• Henke JM, Bassler BL. Three parallel quorum-sensing systems regulate gene expression in Vibrio harveyi. J. Bacteriol.186(20), 6902–6914 (2004).
   PubMed Web of Science ®Google Scholar
• Pereira CS, McAuley JR, Taga ME, Xavier KB, Miller ST. Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria. Mol. Microbiol.70, 1223–1235 (2008).
   PubMedGoogle Scholar
• Taga ME, Semmelhack JL, Bassler BL. The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium. Mol. Microbiol.42(3), 777–793 (2001).
   PubMed Web of Science ®Google Scholar
• Xavier KB, Bassler BL. Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. J. Bacteriol.187(1), 238–248 (2005).
   PubMed Web of Science ®Google Scholar
• Shao H, Lamont RJ, Demuth DR. Autoinducer 2 is required for biofilm growth of Aggregatibacter (Actinobacillus) actinomycetemcomitans. Infect. Immun.75(9), 4211–4218 (2007).
   PubMedGoogle Scholar
• Shao H, James D, Lamont RJ, Demuth DR. Differential interaction of Aggregatibacter (Actinobacillus) actinomycetemcomitans LsrB and RbsB proteins with autoinducer 2. J. Bacteriol.189(15), 5559–5565 (2007).
   PubMedGoogle Scholar
• James D, Shao H, Lamont RJ, Demuth DR. The Actinobacillus actinomycetemcomitans ribose binding protein RbsB interacts with cognate and heterologous autoinducer 2 signals. Infect. Immun.74(7), 4021–4029 (2006).
   PubMed Web of Science ®Google Scholar
• Brackman G, Celen S, Baruah K et al. AI-2 quorum-sensing inhibitors affect the starvation response and reduce virulence in several Vibrio species, most likely by interfering with LuxPQ. Microbiology155(Pt 12), 4114–4122 (2009).
   PubMed Web of Science ®Google Scholar
• Lowery CA, Park J, Kaufmann GF, Janda KD. An unexpected switch in the modulation of AI-2-based quorum sensing discovered through synthetic 4,5-dihydroxy-2,3-pentanedione analogues. J. Am. Chem. Soc.130(29), 9200–9201 (2008).
   PubMed Web of Science ®Google Scholar
• Lowery CA, Abe T, Park J et al. Revisiting AI-2 quorum sensing inhibitors: direct comparison of alkyl-DPD analogues and a natural product fimbrolide. J. Am. Chem. Soc.131(43), 15584–15585 (2009).
   PubMed Web of Science ®Google Scholar
• Vendeville A, Winzer K, Heurlier K, Tang CM, Hardie KR. Making ‘sense’ of metabolism: autoinducer-2, LUXS and pathogenic bacteria. Nat. Rev. Micro.3(5), 383–396 (2005).
   PubMed Web of Science ®Google Scholar
• Gopishetty B, Zhu J, Rajan R et al. Probing the catalytic mechanism of S-ribosylhomocysteinase (LuxS) with catalytic intermediates and substrate analogues. J. Am. Chem. Soc.131(3), 1243–1250 (2009).
   PubMed Web of Science ®Google Scholar
• Roy V, Fernandes R, Tsao C-Y, Bentley WE. Cross species quorum quenching using a native AI-2 processing enzyme. ACS Chem. Biol.5(2), 223–232 (2009).
   Google Scholar
• Siller M, Janapatla R, Pirzada Z, Hassler C, Zinkl D, Charpentier E. Functional analysis of the group A streptococcal luxS/AI-2 system in metabolism, adaptation to stress and interaction with host cells. BMC Microbiol.8(1), 188 (2008).
   PubMedGoogle Scholar
• Zhao L, Xue T, Shang F, Sun H, Sun B. Staphylococcus aureus AI-2 quorum sensing associates with the KdpDE two-component system to regulate capsular polysaccharide synthesis and virulence. Infect. Immun.78(8), 3506–3515 (2010).
   PubMed Web of Science ®Google Scholar
• Duan K, Dammel C, Stein J, Rabin H, Surette MG. Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication. Mol. Microbiol.50(5), 1477–1491 (2003).
   PubMed Web of Science ®Google Scholar
• Sperandio V, Torres AG, Jarvis B, Nataro JP, Kaper JB. Bacteria–host communication: the language of hormones. Proc. Natl Acad. Sci. USA100(15), 8951–8956 (2003).
   PubMed Web of Science ®Google Scholar