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Expert Review of Molecular Diagnostics Volume 12, 2012 - Issue 1
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Editorial

Transcriptomic analysis of follicular cells provides information on the chromosomal status and competence of unfertilized oocytes

Elpida Fragouli Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford OX3 9DU, UK and Reprogenetics UK, Oxford OX4 2HW, UK. [email protected]
&
Dagan Wells Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford OX3 9DU, UK and Reprogenetics UK, Oxford OX4 2HW, UK
Pages 1-4 | Published online: 09 Jan 2014

References

  • Gondos B, Westergaard L, Byskov AG. Initiation of oogenesis in the human fetal ovary: ultrastructural and squash preparation study. Am. J. Obstet. Gynecol.155(1), 189–195 (1986).
  • Hunt PA, Hassold TJ. Human female meiosis: what makes a good egg go bad? Trends Genet.24(2), 86–93 (2008).
  • Skinner MK. Regulation of primordial assembly and development. Hum. Reprod. Update11(5), 461–471 (2005).
  • Chian RC, Lim JH, Tan SL. State of the art in vitro oocyte maturation. Curr. Opin. Obstet. Gynecol.16(3), 211–219 (2004).
  • Gilchrist RB, Lane M, Thompson JG. Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality. Hum. Reprod. Update14(2), 159–177 (2008).
  • Su YQ, Sugiura K, Wigglesworth K et al. Oocyte regulation of metabolic cooperativity between mouse cumulus cells and oocytes: BMP15 and GDF9 control cholesterol biosynthesis in cumulus cells. Development135(1), 111–121 (2008).
  • Assou S, Haouzi D, Mahmoud K et al. A non-invasive test for assessing embryo potential by gene expression profiles of human cumulus cells: a proof of concept study. Mol. Hum. Reprod.14(12), 711–719 (2008).
  • Matos L, Stevenson D, Gomes F et al. Superoxide dismutase expression in human cumulus oophorus cells. Mol. Hum. Reprod.15(7), 411–419 (2009).
  • Host E, Gabrielsen A, Lindenberg S et al. Apoptosis in human cumulus cells in relation to zona pellucida thickness variation, maturation stage and cleavage of the corresponding oocyte after intracytoplasmic sperm injection. Fertil. Steril.77(3), 511–515 (2002).
  • Corn CM, Hauser-Kronberger C, Moser M et al. Predictive value of cumulus cells apoptosis with regard to blastocyst development of corresponding gametes. Fertil. Steril.84(3), 627–633 (2005).
  • Hussein TS, Froiland DA, Amato F et al. Oocytes prevent cumulus cell apoptosis by maintaining a morphogenic paracrine gradient of bone morphogenetic proteins. J. Cell Sci.118(Pt 22), 5257–5268 (2005).
  • Patrizio P, Fragouli E, Bianchi V et al. Molecular methods for selection of the ideal oocyte. Reprod. BioMed. Online15(3), 346–353 (2007).
  • Gebhardt KM, Feil DK, Dunning KR et al. Human cumulus cell gene expression as a biomarker of pregnancy outcome after single embryo transfer. Fertil. Steril.96(1), 47.e2–52.e2 (2011).
  • Fragouli E, Alfarawati S, Goodall NN et al. The cytogenetics of polar bodies: insights into female meiosis and the diagnosis of aneuploidy. Mol. Hum. Reprod. doi:10.1093/molehr/gar024 (2011) (Epub ahead of print).
  • Wells D, Fragouli E, Bianchi V, Borini A, Patrizio P. Identification of novel non-invasive biomarkers of oocyte aneuploidy. Fertil. Steril.90, S35 (2008).
  • Fragouli E, Huang Z, Bianchi V et al. Follicle-specific predisposition to aneuploidy as revealed by transcriptomic analysis of cumulus cells. Hum. Reprod.26(Suppl. 1), i87 (2011).

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