Neuroimaging contributions to novel surgical treatments for intractable obsessive–compulsive disorder

References

• Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the national comorbidity survey replication. Arch. Gen. Psychiatry62, 617–627 (2005).
   PubMed Web of Science ®Google Scholar
• Mindus P, Rasmussen SA, Lindquist C. Neurosurgical treatment for refractory obsessive–compulsive disorder: implications for understanding frontal lobe function. J. Neuropsychiatry Clin. Neurosci.6(4), 467–477 (1994).
   PubMed Web of Science ®Google Scholar
• Nuttin B, Cosyns P, Demeulemeester H, Gybels J, Meyerson B. Electrical stimulation in anterior limbs of internal capsules in patients with obsessive–compulsive disorder. Lancet354(9189), 1526 (1999).
   PubMed Web of Science ®Google Scholar
• Dougherty DD, Rauch SL. Brain correlates of antidepressant treatment outcome from neuroimaging studies in depression. Psychiatr. Clin. North Am.30(1), 91–103 (2007).
   PubMed Web of Science ®Google Scholar
• Borairi S, Dougherty DD. The use of neuroimaging to predict treatment response for neurosurgical interventions for treatment-refractory major depression and obsessive–compulsive disorder. Havard Rev. Psychiatry19(3), 155–161 (2011).
   PubMed Web of Science ®Google Scholar
• Husted DS, Shapira NA. A review of the treatment for refractory obsessive–compulsive disorder: from medicine to deep brain stimulation. CNS Spectr.9(11), 833–847 (2004).
   PubMed Web of Science ®Google Scholar
• Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann. Rev. Neurosci.9, 357–381 (1986).
   PubMed Web of Science ®Google Scholar
• Haber SN, Calzavara R. The cortico–basal ganglia integrative network: the role of the thalamus. Brain Res. Bull.78(2–3), 69–74 (2009).
   PubMed Web of Science ®Google Scholar
• Dougherty DD, Rauch SL, Greenberg BD. Pathophysiology of obsessive–compulsive disorder. In: Textbook of Anxiety Disorders 2nd Edition. Stein D, Hollander E, Rothbaum B (Eds). American Psychiatric Publishing Inc., Washington DC, USA, 287–310 (2010).
   Google Scholar
• Rauch SL, Jenike MA, Alpert NM et al. Regional cerebral blood flow measured during symptom provocation in obsessive–compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. Arch. Gen. Psychiatry51(1), 62–70 (1994).
   PubMed Web of Science ®Google Scholar
• Baxter LR Jr, Thompson JM, Schwartz JM et al. Trazodone treatment response in obsessive–compulsive disorder – correlated with shifts in glucose metabolism in the caudate nuclei. Psychopathology20(1), 114–122 (1987).
   PubMedGoogle Scholar
• Shah DB, Pesiridou A, Baltuch GH, Malone DA, O’Reardon JP. Functional neurosurgery in the treatment of severe obsessive compulsive disorder and major depression: overview of disease circuits and therapeutic targeting for the clinician. Psychiatry5(9), 24–33 (2008).
   PubMedGoogle Scholar
• Rauch SL, Makris N, Cosgrove GR et al. A magnetic resonance imaging study of regional cortical volumes following stereotactic anterior cingulotomy. CNS Spectr.6(3), 214–222 (2001).
   PubMedGoogle Scholar
• Gilbert AR, Mataix-Cols D, Almeida JR et al. Brain structure and symptom dimension relationships in obsessive–compulsive disorder: a voxel-based morphometry study. J. Affect. Disord.109(1–2), 117–126 (2008).
   PubMedGoogle Scholar
• Kang DH, Kim JJ, Choi JS et al. Volumetric investigation of the frontal-subcortical circuitry in patients with obsessive–compulsive disorder. J. Neuropsychiatry Clin. Neurosci.16(3), 342–349 (2004).
   PubMed Web of Science ®Google Scholar
• Choi JS, Kang DH, Kim JJ et al. Left anterior subregion of orbitofrontal cortex volume reduction and impaired organizational strategies in obsessive–compulsive disorder. J. Psychiatr. Res.38(2), 193–199 (2004).
   PubMed Web of Science ®Google Scholar
• Cecconi JP, Lopes AC, Duran FL et al. Gamma ventral capsulotomy for treatment of resistant obsessive–compulsive disorder: a structural MRI pilot prospective study. Neurosci. Lett.447(2–3), 138–142 (2008).
   PubMedGoogle Scholar
• Rotge JY, Langbour N, Guehl D et al. Gray matter alterations in obsessive–compulsive disorder: an anatomic likelihood estimation meta-analysis. Neuropsychopharmacology35(3), 686–691 (2010).
   PubMed Web of Science ®Google Scholar
• Szeszko PR, Christian C, Macmaster F et al. Gray matter structural alterations in psychotropic drug-naive pediatric obsessive–compulsive disorder: an optimized voxel-based morphometry study. Am. J. Psychiatry165(10), 1299–1307 (2008).
   PubMed Web of Science ®Google Scholar
• Valente AA Jr, Miguel EC, Castro CC et al. Regional gray matter abnormalities in obsessive–compulsive disorder: a voxel-based morphometry study. Biol. Psychiatry58(6), 479–487 (2005).
   PubMed Web of Science ®Google Scholar
• Menzies L, Chamberlain SR, Laird AR, Thelen SM, Sahakian BJ, Bullmore ET. Integrating evidence from neuroimaging and neuropsychological studies of obsessive–compulsive disorder: the orbitofronto-striatal model revisited. Beurosci. Biobehav. Rev.32(3), 525–549 (2008).
   PubMed Web of Science ®Google Scholar
• Pujol J, Soriano-Mas C, Alonso P et al. Mapping structural brain alterations in obsessive–compulsive disorder. Arch. Gen. Psychiatry61(7), 720–730 (2004).
   PubMed Web of Science ®Google Scholar
• Szeszko PR, MacMillan S, McMeniman M et al. Brain structural abnormalities in psychotropic drug-naive pediatric patients with obsessive–compulsive disorder. Am. J. Psychiatry161, 1049–1056 (2004).
   PubMed Web of Science ®Google Scholar
• Gilbert AR, Moore GJ, Keshavan MS et al. Decrease in thalamic volumes of pediatric patients with obsessive–compulsive disorder who are taking paroxetine. Arch. Gen. Psychiatry57(5), 449–456 (2000).
   PubMed Web of Science ®Google Scholar
• Goodman WK. Obsessive–compulsive disorder: diagnosis and treatment. J. Clin. Psychiatry60(18), 27–32 (1999).
   PubMed Web of Science ®Google Scholar
• Goodman WK, Price LH, Rasmussen SA et al. The Yale–Brown obsessive compulsive scale. Arch. Gen. Psychiatry46(11), 1012–1016 (1989).
   PubMed Web of Science ®Google Scholar
• Garibotto V, Scifo P, Gorini A et al. Disorganization of anatomical connectivity in obsessive compulsive disorder: a multi-parameter diffusion tensor imaging study in a subpopulation of patients. Neurobiol. Dis.37(2), 468–476 (2010).
   PubMed Web of Science ®Google Scholar
• Nakamae T, Narumoto J, Shibata K et al. Alteration of fractional anisotropy and apparent diffusion coefficient in obsessive–compulsive disorder: a diffusion tensor imaging study. Prog. Neuropsychopharmacol. Biol. Psychiatry32(5), 1221–1226 (2008).
   PubMedGoogle Scholar
• Fontenelle LF, Harrison BJ, Yücel M, Pujol J, Fujiwara H, Pantelis C. Is there evidence of brain white-matter abnormalities in obsessive–compulsive disorder?: a narrative review. Top. Mag. Reson. Imaging20(5), 291–298 (2009).
   PubMedGoogle Scholar
• Ebert D, Speck O, König A, Berger M, Hennig J, Hohagen F. 1H-magnetic resonance spectroscopy in obsessive–compulsive disorder: evidence for neuronal loss in the cingulate gyrus and the right striatum. Psychiatry Res.74(3), 173–176 (1997).
   PubMed Web of Science ®Google Scholar
• Bartha R, Stein MB, Williamson PC. A short echo 1H spectroscopy and volumetric MRI study of the corpus striatum in patients with obsessive–compulsive disorder and comparison subjects. Am. J. Psychiatry155(11), 1584–1591 (1998).
   PubMed Web of Science ®Google Scholar
• Dougherty DD, Greenberg BD. Neurobiology and neurosircuitry of obsessive–compulsive disorder and relevance to its surgical treatment. In: Clinical Obsesstive-Compulsive Disorder is Adults and Children. Hudak R, Dougherty DD (Eds). Cambridge University Press, New York, NY, USA, 20–29 (2011).
   Google Scholar
• Rauch SL, Dougherty DD, Malone D et al. A functional neuroimaging investigation of deep brain stimulation in patients with obsessive–compulsive disorder. J. Neurosurg.104(4), 558–565 (2006).
   PubMed Web of Science ®Google Scholar
• Cosgrove GR. Surgery for psychiatric disorders. CNS Spectr.5(10), 43–52 (2000).
   PubMedGoogle Scholar
• Dougherty DD, Baer L, Cosgrove GR et al. Prospective long-term follow-up of 44 patients who received cingulotomy for treatment-refractory obsessive–compulsive disorder. Am. J. Psychiatry159(2), 269–275 (2002).
   PubMed Web of Science ®Google Scholar
• Liu K, Zhang H, Liu C et al. Stereotactic treatment of refractory obsessive compulsive disorder by bilateral capsulotomy with 3 years follow-up. J. Clin. Neurosci.15(6), 622–629 (2008).
   PubMedGoogle Scholar
• Lopes AC, Greenberg BD, Norén G et al. Treatment of resistant obsessive–compulsive disorder with ventral capsular/ventral striatal gamma capsulotomy: a pilot prospective study. J. Neuropsychiatry Clin. Neurosci.21, 381–392 (2009).
   PubMed Web of Science ®Google Scholar
• Ruck C, Karlsson A, Steele D et al. Capsulotomy for obsessive–compulsive disorder: long-term follow-up of 25 patients. Arch. Gen. Psychiatry65(8), 914–921 (2008).
   PubMedGoogle Scholar
• Greenberg BD, Malone DA, Friehs GM et al. Three-year outcomes in deep brain stimulation for highly resistant obsessive–compulsive disorder. Neuropsychopharmacology31(11), 2384–2393 (2006).
   PubMed Web of Science ®Google Scholar
• Mallet L, Polosan M, Jaafari N et al. Subthalamic nucleus stimulation in severe obsessive–compulsive disorder. N. Engl. J. Med.359(20), 2121–2134 (2008).
   PubMed Web of Science ®Google Scholar
• Denys D, Mantione M, Figee M et al. Deep brain stimulation of the nucleus accumbens for treatment-refractory obsessive–compulsive disorder. Arch. Gen. Psychiatry67(10), 1061–1068 (2010).
   PubMed Web of Science ®Google Scholar
• Aouizerate B, Cuny E, Martin-Guehl C et al. Deep brain stimulation of the ventral caudate nucleus in the treatment of obsessive–compulsive disorder and major depression: case report. J. Neurosurg.101(4), 682–686 (2004).
   PubMed Web of Science ®Google Scholar
• Jiménez-Ponce F, Velasco-Campos F, Castro-Farfán G et al. Preliminary study in patients with obsessive–compulsive disorder treated with electrical stimulation in the inferior thalamic peduncle. Neurosurgery65(6), 203–209 (2009).
   PubMed Web of Science ®Google Scholar
• Abelson JL, Curtis GC, Sagher O et al. Deep brain stimulation for refractory obsessive–compulsive disorder. Biol. Psychiatry57(5), 510–516 (2005).
   PubMed Web of Science ®Google Scholar
• de Koning PP, Figee M, van den Munckhof P, Schuurman PR, Denys D. Current status of deep brain stimulation for obsessive–compulsive disorder: a clinical review of different targets. Curr. Psychiatry. Rep.13(4), 274–282 (2011).
   PubMedGoogle Scholar
• Greenberg BD, Gabriels LA, Malone DA Jr et al. Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive–compulsive disorder: worldwide experience. Mol. Psychiatry15(1), 64–79 (2010).
   PubMed Web of Science ®Google Scholar
• Goodman WK, Foote KD, Greenberg BD et al. Deep brain stimulation for intractable obsessive compulsive disorder: pilot study using a blinded, staggered-onset design. Biol. Psychiatry67(6), 535–542 (2010).
   PubMed Web of Science ®Google Scholar
• Mallet L, Mesnage V, Houeto JL et al. Compulsions, Parkinson’s disease, and stimulation. Lancet360(9342), 1302–1304 (2002).
   PubMed Web of Science ®Google Scholar
• Le Jeune F, Vérin M, N’Diaye K et al. Decrease of prefrontal metabolism after subthalamic stimulation in obsessive–compulsive disorder: a positron emission tomography study. Biol. Psychiatry68(11), 1016–1022 (2010).
   PubMedGoogle Scholar
• Figee M, Vink M, de Geus F et al. Dysfunctional reward circuitry in obsessive–compulsive disorder. Biol. Psychiatry69(9), 867–874 (2011).
   PubMed Web of Science ®Google Scholar
• Lozano AM, Eltahawy H. How does DBS work? Suppl. Clin. Neurophysiol.57, 733–736 (2004).
   PubMedGoogle Scholar
• Brody AL, Saxena S, Schwartz JM et al. FDG-PET predictors of response to behavioral therapy and pharmacotherapy in obsessive compulsive disorder. Psychiatry Res.84(1), 1–6 (1998).
   PubMed Web of Science ®Google Scholar
• Saxena S, Brody AL, Maidment KM et al. Localized orbitofrontal and subcortical metabolic changes and predictors of response to paroxetine treatment in obsessive–compulsive disorder. Neuropsychopharmacology21(6), 683–693 (1999).
   PubMed Web of Science ®Google Scholar
• Rauch SL, Shin LM, Dougherty DD et al. Predictors of fluvoxamine response in contamination-related obsessive compulsive disorder: a PET symptom provocation study. Neuropsychopharmacology27(5), 782–791 (2002).
   PubMed Web of Science ®Google Scholar
• Rauch SL, Dougherty DD, Cosgrove GR et al. Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for obsessive compulsive disorder. Biol. Psychiatry50(9), 659–667 (2001).
   PubMed Web of Science ®Google Scholar
• Van Laere K, Nuttin B, Gabriels L et al. Metabolic imaging of anterior capsular stimulation in refractory obsessive–compulsive disorder: a key role for the subgenual anterior cingulate and ventral striatum. J. Nucl. Med.47(5), 740–747 (2006).
   PubMed Web of Science ®Google Scholar
• Charmichael ST, Price JL. Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys. J. Comp. Neurol.363, 615–641 (2002).
   Google Scholar
• Knight DC, Smith CN, Cheng DT, Stein EA, Helmstetter FJ. Amygdala and hippocampal activity during acquisition and extinction of human fear conditioning. Cogn. Affect. Behav. Neurosci.4(3), 317–325 (2004).
   PubMedGoogle Scholar
• Phelps EA, Delgado MR, Nearing KI, LeDoux JE. Extinction learning in humans: role of the amygdala and vmPFC. Neuron43(6), 897–905 (2004).
   PubMed Web of Science ®Google Scholar
• Alvarez RP, Biggs A, Chen G, Pine DS, Grillon C. Contextual fear conditioning in humans: cortical–hippocampal and amygdala contributions. J. Neurosci.28(24), 6211–6219 (2008).
   PubMed Web of Science ®Google Scholar
• Büchel C, Morris J, Dolan RJ, Friston KJ. Brain systems mediating aversive conditioning: an event-related fMRI study. Neuron20(5), 947–957 (1998).
   PubMed Web of Science ®Google Scholar
• Dunsmoor JE, Bandettini PA, Knight DC. Impact of continuous versus intermittent CS-UCS pairing on human brain activation during Pavlovian fear conditioning. Behav. Neurosci.121(4), 635–642 (2007).
   PubMed Web of Science ®Google Scholar
• Milad MR, Quirk GJ, Pitman RK, Orr SP, Fischl B, Rauch SL. A role for the human dorsal anterior cingulate cortex in fear expression. Biol. Psychiatry62(10), 1191–1194 (2007).
   PubMed Web of Science ®Google Scholar
• Milad MR, Wright CI, Orr SP, Pitman RK, Quirk GJ, Rauch SL. Recall of fear extinction in humans activates the ventromedial prefrontal cortex and hippocampus in concert. Biol. Psychiatry62(5), 446–454 (2007).
   PubMed Web of Science ®Google Scholar
• Furmark T, Fischer H, Wik G, Larsson M, Fredrikson M. The amygdala and individual differences in human fear conditioning. Neuroreport8(18), 3957–3960 (1997).
   PubMedGoogle Scholar
• LaBar KS, Gatenby JC, Gore JC, LeDoux JE, Phelps EA. Human amygdala activation during conditioned fear acquisition and extinction: a mixed-trial fMRI study. Neuron20(5), 937–945 (1998).
   PubMed Web of Science ®Google Scholar
• Phelps EA, O’Connor KJ, Gatenby JC, Gore JC, Grillon C, Davis M. Activation of the left amygdala to a cognitive representation of fear. Nat. Neurosci.4(4), 437–441 (2001).
   PubMed Web of Science ®Google Scholar
• Buchel C, Dolan RJ, Armony JL, Friston KJ. Amygdala–hippocampal involvement in human aversive trace conditioning revealed through event-related functional magnetic resonance imaging. J. Neurosci.19(24), 10869–10876 (1999).
   PubMed Web of Science ®Google Scholar
• Gottfried JA, Dolan RJ. Human orbitofrontal cortex mediates extinction learning while accessing conditioned representations of value. Nat. Neurosci.7(10), 1144–1152 (2004).
   PubMedGoogle Scholar
• Knight DC, Waters NS, Bandettini PA. Neural substrates of explicit and implicit fear memory. Neuroimage45, 208–214 (2009).
   PubMed Web of Science ®Google Scholar
• Barrett J, Armony JL. Influence of trait anxiety on brain activity during the acquisition and extinction of aversive conditioning. Psychol. Med.39(2), 255–265 (2009).
   PubMed Web of Science ®Google Scholar
• Milad MR, Quinn BT, Pitman RK, Orr SP, Fischl B, Rauch SL. Thickness of ventromedial prefrontal cortex in humans is correlated with extinction memory. Proc. Natl Acad. Sci. USA102(30), 10706–10711 (2005).
   PubMedGoogle Scholar
• Zeidan MA, Lebron-Milad Z, Thompson-Hollands J et al. Test–retest reliability during fear acquisition and fear extinction in humans. CNS Neurosci. Ther. doi:10.1111/j.1755-5949.2011.00238.x (2011) (Epub ahead of print).
   PubMedGoogle Scholar
• Bremner JD, Vermetten E, Schmahl C et al. Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder. Psychol. Med.35(6), 791–806 (2005).
   PubMed Web of Science ®Google Scholar
• Milad MR, Pitman RK, Ellis CB et al. Neurobiological basis of failure to recall extinction memory in posttraumatic stress disorder. Biol. Psychiatry66(12), 1075–1082 (2009).
   PubMed Web of Science ®Google Scholar
• Rougemont-Bücking A, Linnman C, Zeffiro TA et al. Altered processing of contextual information during fear extinction in PTSD: an fMRI study. CNS Neurosci. Ther.17(4), 227–236 (2010).
   PubMedGoogle Scholar
• Milad MR, Rauch SL. The role of the orbitofrontal cortex in anxiety disorders. Ann. NY Acad. Sci.1121, 546–561 (2007).
   PubMed Web of Science ®Google Scholar
• Boyden ES. A history of optogenetics: the development of tools for controlling brain circuits with light. F1000 Biol. Rep.3, 11 (2011).
   PubMed Web of Science ®Google Scholar