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Expert Review of Respiratory Medicine Volume 6, 2012 - Issue 1
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Letter to the Editor

Are we sure about the evidence for zinc in prophylaxis of the common cold?

Jaime L Peters Peninsula Medical School, University of Exeter, Exeter, UK. [email protected]
,
Santiago G Moreno Department of Evaluation of Innovation and New Technologies, Fundació Clinic, Barcelona, Spain
,
Bob Phillips Centre for Reviews and Dissemination, University of York, York, UK
&
Alex J Sutton Department of Health Sciences, University of Leicester, Leicester, UK
Pages 15-16 | Published online: 09 Jan 2014

References

  • Singh M, Das RR. Clinical potential of zinc in prophylaxis of the common cold. Expert Rev. Respir. Med.5(3), 301–303 (2011).
  • Singh M, Das RR. Zinc for the common cold. Cochrane Database Syst. Rev.2, CD001364 (2011).
  • Kurugol Z, Akilli M, Bayram N, Koturoglu G. The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children. Acta Paediatr.95(10), 1175–1181 (2006).
  • Vakili R, Vahedian M, Khodaei G-H, Mahmoudi M. Effects of zinc supplementation in occurrence and duration of common cold in school aged children during cold season: a double-blind placebo-controlled trial. Iran. J. Pediatr.19(4), 379–380 (2009).
  • McElroy BH, Miller SP. Effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) against the common cold in school-aged subjects: a retrospective chart review. Am. J. Ther.9(6), 472–475 (2002).
  • McElroy BH, Miller SP. An open-label, single-centre, Phase IV clinical study of the effectiveness of zinc gluconate glycine lozenges (Cold-Eeze) in reducing the duration and symptoms of the common cold in school-aged subjects. Am. J. Ther.10(5), 324–329 (2003).
  • Peters JL, Sutton AJ, Jones DR et al. Contour enhanced funnel plots help distinguish publication bias from other causes of asymmetry. J. Clin. Epidemiol.61(10), 991–996 (2008).
  • Chan A-W, Hróbjartsson A, Haahr MT et al. Empirical evidence for selective reporting of outcomes in randomized trials. Comparison of protocols to published articles. J. Am. Med. Assoc.291(20), 2457–2465 (2004).
  • Higgins JPT, Green S. Cochrane Handbook for Systematic Reviews of Interventions. Version 5.0.2. Higgins JPT, Green S (Eds). The Cochrane Collaboration, London, UK (2009).

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