313
Views
46
CrossRef citations to date
0
Altmetric
Review

Experimental rabies vaccines for humans

Pages 1177-1186 | Published online: 09 Jan 2014

References

  • Jackson AC. Rabies. Neurolog. Clin.26(3), 717–726 (2008).
  • WHO. Rabies and Envenomings, a Neglected Public Health Issue. Report of a Consultative Meeting. WHO, Geneva, Switzerland (2007).
  • Blanton JD, Palmer D, Christian KA, Rupprecht CE. Rabies surveillance in the United States during 2007. J. Am. Vet. Med. Assoc.233(6), 884–897 (2008).
  • Plotkin SA. Vaccines: correlates of vaccine-induced immunity. Clin. Infect. Dis.47(3), 401–409 (2008).
  • Turner GS. Immunoglobulin (IgG) and (IgM) antibody responses to rabies vaccine. J. Gen. Virol.40, 595–604 (1978).
  • Perry LL, Lodmell DL. Role of CD4+ and CD8+ T cells in murine resistance to street rabies virus. J. Virol.65(7), 3429–3434 (1991).
  • Brinkman DM, Jol-van der Zijde CM, ten Dam MM et al. Vaccination with rabies to study the humoral and cellular immune response to a T-cell dependent neoantigen in man. J. Clin. Immunol.23(6), 528–538 (2003).
  • Perrin P, Joffret ML, Zanetti C et al. Rabies-specific production of interleukin-2 by peripheral blood lymphocytes from human rabies vaccinees. Vaccine9(8), 549–558 (1991).
  • Uytdehaag FG, Osterhaus AD, Loggen HG et al. Induction of antigen-specific antibody response in human peripheral blood lymphocytes in vitro by a dog kidney cell vaccine against rabies virus (DKCV). J. Immunol. (Baltimore)131(3), 1234–1239 (1983).
  • Moore SM, Wilkerson MJ, Davis RD, Wyatt CR, Briggs DJ. Detection of cellular immunity to rabies antigens in human vaccinees. J. Clin. Immunol.26(6), 533–545 (2006).
  • Blanchard-Rohner G, Pulickal AS, Jol-van der Zijde CM, Snape MD, Pollard AJ. Appearance of peripheral blood plasma cells and memory B cells in a primary and secondary immune response in humans. Blood114(24), 4998–5002 (2009).
  • Gulati U, Kumari K, Wu W, Keitel WA, Air GM. Amount and avidity of serum antibodies against native glycoproteins and denatured virus after repeated influenza whole-virus vaccination. Vaccine23(11), 1414–1425 (2005).
  • Otvos L Jr, Hollosi M, Perczel A, Dietzschold B, Fasman GD. Phosphorylation loops in synthetic peptides of the human neurofilament protein middle-sized subunit. J. Protein Chem.7(4), 365–376 (1988).
  • Johnson N, Cunningham AF, Fooks AR. The immune response to rabies virus infection and vaccination. Vaccine28(23), 3896–3901 (2010).
  • WHO. WHO Position Paper on rabies vaccines. Weekly Epidemiol. Record82(49/50), 425–436 (2007).
  • Rupprecht CE, Briggs D, Brown CM et al. Use of a reduced (4-dose) vaccine schedule for postexposure prophylaxis to prevent human rabies: recommendations of the advisory committee on immunization practices. MMWR Morb. Mortal. Weekly Rep.59(RR-2), 1–9 (2010).
  • Warrell MJ, Suntharasamai P, Nicholson KG et al. Multi-site intradermal and multi-site subcutaneous rabies vaccination: improved economical regimens. Lancet1(8382), 874–876 (1984).
  • Suntharasamai P, Warrell MJ, Viravan C et al. Purified chick embryo cell rabies vaccine: economical multisite intradermal regimen for post-exposure prophylaxis. Epidemiol. Infect.99(3), 755–765 (1987).
  • Lang J, Hoa DQ, Gioi NV et al. Immunogenicity and safety of low-dose intradermal rabies vaccination given during an expanded programme on immunization session in Viet Nam: results of a comparative randomized trial. Trans. Royal Soc. Trop. Med. Hygiene93(2), 208–213 (1999).
  • Warrell MJ, Riddell A, Yu LM et al. A simplified 4-site economical intradermal post-exposure rabies vaccine regimen: a randomised controlled comparison with standard methods. PLoS Neglect. Trop. Dis.2(4), e224 (2008).
  • Strady C, Andreoletti L, Baumard S et al. Immunogenicity and booster efficacy of pre-exposure rabies vaccination. Trans. Royal Soc. Trop. Med. Hygiene103(11), 1159–1164 (2009).
  • Cenna J, Tan GS, Papaneri AB et al. Immune modulating effect by a phosphoprotein-deleted rabies virus vaccine vector expressing two copies of the rabies virus glycoprotein gene. Vaccine26(50), 6405–6414 (2008).
  • O’Hagan DT, De Gregorio E. The path to a successful vaccine adjuvant – ‘the long and winding road’. Drug Discov. Today14(11–12), 541–551 (2009).
  • Ertl HC. Novel vaccines to human rabies. PLoS Neglect. Trop. Dis. (Electronic Resource)3(9), e515 (2009).
  • Wang X, Bao M, Wan M et al. A CpG oligodeoxynucleotide acts as a potent adjuvant for inactivated rabies virus vaccine. Vaccine26(15), 1893–1901 (2008).
  • Ramya R, Verma PC, Chaturvedi VK et al. Poly(lactide-co-glycolide) microspheres: a potent oral delivery system to elicit systemic immune response against inactivated rabies virus. Vaccine27(15), 2138–2143 (2009).
  • Chulasugandha P, Khawplod P, Havanond P, Wilde H. Cost comparison of rabies pre-exposure vaccination with post-exposure treatment in Thai children. Vaccine24(9), 1478–1482 (2006).
  • Kamoltham T, Thinyounyong W, Phongchamnaphai P et al. Pre-exposure rabies vaccination using purified chick embryo cell rabies vaccine intradermally is immunogenic and safe. J. Pediatrics151(2), 173–177 (2007).
  • Lang J, Duong GH, Nguyen VG et al. Randomised feasibility trial of pre-exposure rabies vaccination with DTP-IPV in infants. Lancet349(9066), 1663–1665 (1997).
  • Lang J, Feroldi E, Vien NC. Pre-exposure purified vero cell rabies vaccine and concomitant routine childhood vaccinations: 5-year post-vaccination follow-up study of an infant cohort in Vietnam. J. Trop. Pediatrics55(1), 26–31 (2009).
  • Lumbiganon P, Chaiprasithikul P, Sookpranee T, Paholpak S, Wasi C. Pre-exposure vaccination with purified chick embryo cell rabies vaccines in children. Asian Pacif. J. Allergy Immunol.7(2), 99–101 (1989).
  • Pengsaa K, Limkittikul K, Sabchareon A et al. A three-year clinical study on immunogenicity, safety, and booster response of purified chick embryo cell rabies vaccine administered intramuscularly or intradermally to 12- to 18-month-old Thai children, concomitantly with Japanese encephalitis vaccine. Pediatr. Infect. Dis. J.28(4), 335–337 (2009).
  • Shanbag P, Shah N, Kulkarni M et al. Protecting Indian schoolchildren against rabies: pre-exposure vaccination with purified chick embryo cell vaccine (PCECV) or purified verocell rabies vaccine (PVRV). Hum. Vaccines4(5), 365–369 (2008).
  • Dodet B, Asian Rabies Expert B. An important date in rabies history. Vaccine25(52), 8647–8650 (2007).
  • Marciani DJ. Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity. Drug Discov. Today8(20), 934–943 (2003).
  • Weyer J, Rupprecht CE, Nel LH. Poxvirus-vectored vaccines for rabies – a review. Vaccine27(51), 7198–7201 (2009).
  • Ertl HC. Rabies DNA vaccines for protection and therapeutic treatment. Expert Opin. Biol. Ther.3(4), 639–644 (2003).
  • Schnell MJ, McGettigan JP, Wirblich C, Papaneri A. The cell biology of rabies virus: using stealth to reach the brain. Nat. Rev. Microbiol.8(1), 51–61 (2010).
  • Wunner WH. Rabies Virus. Jackson AC, Wunner WH (Eds). Elsevier Science, CA, USA (2007).
  • Schnell MJ, Mebatsion T, Conzelmann KK. Infectious rabies viruses from cloned cDNA. EMBO J.13(18), 4195–4203 (1994).
  • McGettigan JP, Pomerantz RJ, Siler CA et al. Second-generation rabies virus-based vaccine vectors expressing human immunodeficiency virus type 1 gag have greatly reduced pathogenicity but are highly immunogenic. J. Virol.77(1), 237–244 (2003).
  • Faul EJ, Aye PP, Papaneri AB et al. Rabies virus-based vaccines elicit neutralizing antibodies, poly-functional CD8+ T cell, and protect rhesus macaques from AIDS-like disease after SIV(mac251) challenge. Vaccine28(2), 299–308 (2009).
  • McKenna PM, Koser ML, Carlson KR et al. Highly attenuated rabies virus-based vaccine vectors expressing simian-human immunodeficiency virus89.6P Env and simian immunodeficiency virusmac239 Gag are safe in rhesus macaques and protect from an AIDS-like disease. J. Infect. Dis.195(7), 980–988 (2007).
  • Dietzschold B, Fields BN. Rhabdoviruses. In: Fields Virology. Lippincott-Raven Publishers, PA, USA, 1137–1152 (1996).
  • Rose JK, Schubert M. Rhabdovirus Genomes and Their Products. Wagner RR (Ed.). Plenum Publishing Corp., NY, USA (1987).
  • Brzozka K, Finke S, Conzelmann KK. Identification of the rabies virus a/b interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3. J. Virol.7673–7681 (2005).
  • Brzozka K, Finke S, Conzelmann KK. Inhibition of interferon signaling by rabies virus phosphoprotein P: activation-dependent binding of STAT1 and STAT2. J. Virol.80(6), 2675–2683 (2006).
  • Shoji Y, Inoue S, Nakamichi K et al. Generation and characterization of P gene-deficient rabies virus. Virology318(1), 295–305; 295–305 (2004).
  • Faber M, Pulmanausahakul R, Hodawadekar SS et al. Overexpression of the rabies virus glycoprotein results in enhancement of apoptosis and antiviral immune response. J. Virol.76(7), 3374–3381 (2002).
  • Megret F, Prehaud C, Lafage M et al. Immunopotentiation of the antibody response against influenza HA with apoptotic bodies generated by rabies virus G-ERA protein-driven apoptosis. Vaccine16(23), 5342–5350 (2005).
  • Mebatsion T, Weiland F, Conzelmann KK. Matrix protein of rabies virus is responsible for the assembly and budding of bullet-shaped particles and interacts with the transmembrane spike glycoprotein G. J. Virol.73(1), 242–250 (1999).
  • Cenna J, Hunter M, Tan GS et al. Replication-deficient rabies virus-based vaccines are safe and immunogenic in mice and nonhuman primates. J. Infect. Dis.200(8), 1251–1260 (2009).
  • Ito N, Sugiyama M, Yamada K et al. Characterization of M gene-deficient rabies virus with advantages of effective immunization and safety as a vaccine strain. Microbiol. Immunol.49(11), 971–979 (2005).
  • Shearer MH, Dark RD, Chodosh J, Kennedy RC. Comparison and characterization of immunoglobulin G subclasses among primate species. Clin. Diag. Lab. Immunol.6(6), 953–958 (1999).
  • Burton DR. Antibodies, viruses and vaccines. Nat. Rev. Immunol.2(9), 706–713 (2002).
  • Phares TW, Kean RB, Mikheeva T, Hooper DC. Regional differences in blood-brain barrier permeability changes and inflammation in the apathogenic clearance of virus from the central nervous system. J. Immunol. (Baltimore)176(12), 7666–7675 (2006).
  • Mebatsion T, Konig M, Conzelmann KK. Budding of rabies virus particles in the absence of the spike glycoprotein. Cell84(6), 941–951 (1996).
  • Gomme EA, Faul EJ, Flomenberg P, McGettigan JP, Schnell MJ. Characterization of a single-cycle rabies virus-based vaccine vector. J. Virol.84(6), 2820–2831 (2010).
  • Griffin DE. Immune responses to RNA-virus infections of the CNS. Nat. Rev. Immunol.3(6), 493–502 (2003).
  • Hooper DC, Phares TW, Fabis MJ, Roy A. The production of antibody by invading B cells is required for the clearance of rabies virus from the central nervous system. PLoS Neglect. Trop. Dis. (Electronic Resource)3(10), e535 (2009).
  • Baer GM, Shaddock JH, Williams LW. Prolonging morbidity in rabid dogs by intrathecal injection of attenuated rabies vaccine. Infect. Immun.12(1), 98–103 (1975).
  • Faber M, Li J, Kean RB et al. Effective preexposure and postexposure prophylaxis of rabies with a highly attenuated recombinant rabies virus. Proc. Natl Acad. Sci. USA106(27), 11300–11305 (2009).
  • Zhao L, Toriumi H, Kuang Y, Chen H, Fu ZF. The roles of chemokines in rabies virus infection: overexpression may not always be beneficial. J. Virol.83(22), 11808–11818 (2009).
  • Belotto A, Leanes LF, Schneider MC, Tamayo H, Correa E. Overview of rabies in the Americas. Virus Res.111(1), 5–12 (2005).
  • Lembo T, Hampson K, Kaare MT et al. The feasibility of canine rabies elimination in Africa: dispelling doubts with data. PLoS Negl. Trop. Dis.4(2), e626 (2010).
  • Schneider MC, Belotto A, Ade MP et al. Current status of human rabies transmitted by dogs in Latin America. Cad Saude Publica23(9), 2049–2063 (2007).
  • Baer GM. The history of rabies. In: Rabies. Jackson AC, Wunner WH (Eds). Elsevier Science CA, USA, 11–19 (2007).

Websites

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.