References
- GaurUAggarwalBBRegulation of proliferation, survival and apoptosis by members of the TNF superfamilyBiochem Pharmacol20036681403140814555214
- KaushanskyKBroudyVCHarlanJMAdamsonJWTumor necrosis factor-alpha and tumor necrosis factor-beta (lymphotoxin) stimulate the production of granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and IL-1 in vivoJ Immunol198814110341034152460533
- BrennanFMChantryDJacksonAMainiRFeldmannMInhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritisLancet198928657244247
- ButlerDMMainiRNFeldmannMBrennanFMModulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonistEur Cytokine Netw199564225230
- Van DullemenHMVan DeventerSJHommesDWTreatment of Crohn’s disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)Gastroenterology199510911291357797011
- TraceyDKlareskogLSassoEHSalfeldJGTakPPTumor necrosis factor antagonist mechanisms of action: a comprehensive reviewPharmacol Ther2008117224427918155297
- SchellekensHHow similar do “biosimilars” need to be?Nat Biotechnol2004221113571359
- CatrinaAIUlfgrenAKLindbladSGrondalLKlareskogLLow levels of apoptosis and high FLIP expression in early rheumatoid arthritis synoviumAnn Rheum Dis2002611093493612228167
- MicheauOLensSGaideOAlevizopoulosKTschoppJNF-kappaB signals induce the expression of c-FLIPMol Cell Biol200121165299530511463813
- WangCYMayoMWKornelukRGGoeddelDVBaldwinASJrNF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activationScience19982815383168016839733516
- AzevedoVFAre we prepared to prescribe biosimilars?Rev Bras Reumatol2010503221224
- McCamishMWoollettGThe state of the art in the development of biosimilarsClinical pharmacology and Therapeutics201291340541722318617
- CalvoBZúñigaLMedicamentos Biotecnológicos: Requisitos Exigidos para el Desarrollo y Aprobación de Biosimilares. [Biological Medicinal Products: Requirements for the Development and Approval of Biosimilars]Información tecnológica2010216125132 Spanish
- CaiXYGoutyDBaughmanSRamakrishnanMCullenCRecommendations and requirements for the design of bioanalytical testing used in comparability studies for biosimilar drug developmentBioanalysis20113553554021388266
- FDA Guidance for Industry Scientific Considerations in Demonstrating Biosimilarity to a Reference Product.
- European Medicines AgencyGuideline on similar biological medicinal products containing biotechnology-derived proteins as active substance: quality issues
- PintoVFEstudos clínicos de não-inferioridade: fundamentos e controvérsias. [Non-inferiority clinical trials: concepts and issues]J Vasc Bras201093145151 Portuguese
- MakrygiannakisDCatrinaAIApoptosis as a mechanism of action of tumor necrosis factor antagonists in rheumatoid arthritisJ Rheumatol201239467968522422498
- AtreyaRZimmerMBartschBAntibodies against tumor necrosis factor (TNF) induce T-cell apoptosis in patients with inflammatory bowel diseases via TNF receptor 2 and intestinal CD14+ macrophagesGastroenterology2011141620262038
- CatrinaAITrollmoCaf KlintEEvidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints: extended reportArthritis Rheum20055216172
- LügeringASchmidtMLügeringNPauelsHGDomschkeWKucharzikTInfliximab induces apoptosis in monocytes from patients with chronic active Crohn’s disease by using a caspase-dependent pathwayGastroenterology200112151145115711677207
- MicheauOTschoppJInduction of TNF receptor I-mediated apoptosis via two sequential signaling complexesCell2003114218119012887920
- OttonelloLSynovial fluid from patients with rheumatoid arthritis inhibits neutrophil apoptosis: role of adenosine and proinflammatory cytokinesRheumatology (Oxford)200241111249126012421997
- AngermeierMEckardt-SchuppFMoertlSA novel function of Ubc13 in TNFR1 receptor activationCell Signal20102291388139620472056
- BoglioloBFGPatologia Geral. [General Pathology]4a editionRio de JaneiroGuanabara Koogan2009378 Portuguese
- Enbrel (Etanercept) [prescribing information]Immunex Corporation2007
- Remicade (infliximab) [prescribing information]Centocor I2006
- Humira (adalimumab) [prescribing information]Laboratories A2007
- Cimzia (Certolizumab pegol) [prescribing information]UCB I2009
- Simponi (Golimumab) [prescribing information]Centocor I2009
- SchreiberSKhaliq-KareemiMLawranceICMaintenance therapy with certolizumab pegol for Crohn’s diseaseN Engl J Med2007357323925017634459
- VoulgariPVGolimumab: a new anti-TNF-alpha agent for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitisExpert Rev Clin Immunol20106572173320828280
- GoelNStephensSCertolizumab pegolMAbs20102213714720190560
- PappasDABathonJMHanicqDYasothanUKirkpatrickPGolimumabNature reviews Drug Discovery20098695696
- SchreiberSCertolizumab pegol for the treatment of Crohn’s diseaseTherap Adv Gastroenterol201146375389
- WongMZiringDKorinYTNFalpha blockade in human diseases: mechanisms and future directionsClin Immunol2008126212113617916444
- ShenCVan AsscheGRutgeertsPCeuppensJLCaspase activation and apoptosis induction by adalimumab: demonstration in vitro and in vivo in a chimeric mouse modelInflamm Bowel Dis2006121222816374254
- HoriuchiTMitomaHHarashimaSTsukamotoHShimodaTTransmembrane TNF-alpha: structure, function and interaction with anti-TNF agentsRheumatology (Oxford)20104971215122820194223
- ShealyDCaiAStaquetKCharacterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor alphaMAbs Epub71201024
- Van den BrandeJMHBraatHVan den BrinkGRInfliximab but not etanercept induces apoptosis in lamina propria T- lymphocytes from patients with Crohn’s diseaseGastroenterology200312471774178512806611
- BourneTFossatiGNesbittAA PEGylated Fab’ fragment against tumor necrosis factor for the treatment of Crohn disease: exploring a new mechanism of actionBioDrugs200822533133718778114
- NesbittAFossatiGBerginMMechanism of action of certolizumab pegol (CDP870): in vitro comparison with other anti-tumor necrosis factor alpha agentsInflamm Bowel Dis200713111323133217636564
- Di SabatinoACiccocioppoRCinqueBDefective mucosal T cell death is sustainably reverted by infliximab in a caspase dependent pathway in Crohn’s diseaseGut2004531707714684579
- OhshimaSMimaTSasaiMTumour necrosis factor alpha (TNF-alpha) interferes with Fas-mediated apoptotic cell death on rheumatoid arthritis (RA) synovial cells: a possible mechanism of rheumatoid synovial hyperplasia and a clinical benefit of anti-TNF-alpha therapy for RACytokine200012328128810704256
- MeuschURossolMBaerwaldCHauschildtSWagnerUOutside-to-inside signaling through transmembrane tumor necrosis factor reverses pathologic interleukin-1beta production and deficient apoptosis of rheumatoid arthritis monocytesArthritis Rheum20096092612262119714631
- Van DeventerSJTransmembrane TNF-alpha, induction of apoptosis, and the efficacy of TNF-targeting therapies in Crohn’s diseaseGastroenterology200112151242124611677219
- MitomaHHoriuchiTHattaNInfliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alphaGastroenterology2005128237639215685549
- PattaciniLBoiardiLCasaliBSalvaraniCDifferential effects of anti-TNF-alpha drugs on fibroblast-like synoviocyte apoptosisRheumatology (Oxford)201049348048920040530
- TaylorPCPetersAMPaleologEReduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritisArthritis Rheum2000431384710643698
- HermanSZurgilNMachlavSDistinct effects of anti-tumor necrosis factor combined therapy on TH1/TH2 balance in rheumatoid arthritis patientsClin Vaccine Immunol20111871077108221593236
- AravenaOPesceBSotoLAnti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands IFN-γ-producing NK cell and regulatory T cell subsetsImmunobiology2011216121256126321840621
- VosACWWildenbergMEDuijvesteinMVerhaarAPVan den BrinkGRHommesDWAnti-tumor necrosis factor-α antibodies induce regulatory macrophages in an Fc region-dependent mannerGastroenterology20111401221230
- KaymakcalanZSakorafasPBoseSComparisons of affinities, avidities, and complement activation of adalimumab, infliximab, and etanercept in binding to soluble and membrane tumor necrosis factorClin Immunol20091312308316
- FriesWMujaCCrisafulliCInfliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitisInt J Med Sci20085416918018645606
- EderPLykowska-SzuberLKrela-KazmierczakIStawczyk-EderKZabelMLinkeKThe influence of infliximab and adalimumab on the expression of apoptosis-related proteins in lamina propria mononuclear cells and enterocytes in Crohn’s disease – an immunohistochemical studyJ Crohns Colitis20137970671623021876
- SmithMDWeedonHPapangelisVWalkerJRoberts-ThomsonPJAhernMJApoptosis in the rheumatoid arthritis synovial membrane: modulation by disease-modifying anti-rheumatic drug treatmentRheumatology (Oxford)201049586287520147446
- OakleyFMesoMIredaleJPInhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosisGastroenterology2005128110812015633128
- KimWUYooS-AMinS-YHydroxychloroquine potentiates Fas-mediated apoptosis of rheumatoid synoviocytesClin Exp Immunol2006144350331116734620
- NielsenCHAlbertsenLBendtzenKBaslundBMethotrexate induces poly(ADP-ribose) polymerase-dependent, caspase 3-independent apoptosis in subsets of proliferating CD4+ T cellsClin Exp Immunol2007148228829517286800
- StraussGOsenWDebatinKMInduction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugsClin Exp Immunol2002128225526611985515
- MalaviyaRSunYTanJKEtanercept induces apoptosis of dermal dendritic cells in psoriatic plaques of responding patientsJ Am Acad Dermatol200655459059717010737
- GoedkoopAYKraanMCPicavetDIDeactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre studyArthritis Research and Therapy200464R326R33415225368
- PerlmanHPagliariLJNguyenNBradleyKLiuHPopeRMThe Fas-FasL death receptor and PI3K pathways independently regulate monocyte homeostasisEur J Immunol20013182421243011500826
- PalaoGSantiagoBGalindoMPayáMRamirezJCPablosJLDown-regulation of FLIP sensitizes rheumatoid synovial fibroblasts to Fas-mediated apoptosisArthritis Rheum20045092803281015457448
- SchedelJGayREKuenzlerPFLICE-inhibitory protein expression in synovial fibroblasts and at sites of cartilage and bone erosion in rheumatoid arthritisArthritis Rheum20024661512151812115181
- WuFXWuLJLuoXYExpression of FLICE-inhibitory protein in synovial tissue and its association with synovial inflammation in juvenile idiopathic arthritisChin Med Sci J2010251202620449949
- BaiSLiuHChenK-HNF-kappaB-regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor alpha-mediated apoptosisArthritis Rheum200450123844385515593196
- HammakerDSweeneySFiresteinGSSignal transduction networks in rheumatoid arthritisAnn Rheum Dis200362Suppl 2ii86ii8914532158
- PagliariLJPerlmanHLiuHPopeRMMacrophages require constitutive NF-kappaB activation to maintain A1 expression and mitochondrial homeostasisMol Cell Biol200020238855886511073986
- ZhangHGHydeKPageGPNovel tumor necrosis factor alpha-regulated genes in rheumatoid arthritisArthritis Rheum200450242043114872484
- CollantesEValle BlázquezMMazorraVMachoAArandaEMuñozENuclear factor-kappa B activity in T cells from patients with rheumatic diseases: a preliminary reportAnn Rheum Dis1998571273874110070274
- FujisawaKAonoHHasunumaTYamamotoKMitaSNishiokaKActivation of transcription factor NF-kappa B in human synovial cells in response to tumor necrosis factor alphaArthritis Rheum19963921972038849369