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Biologics: Targets and Therapy

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Cover image for Biologics: Targets and Therapy, Volume 8, 2014

Biologics: Targets and Therapy, Volume 8, Issue (2014)

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Biologics: Targets and Therapy, Volume 8, Issue (2014)

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Review

Review Article

Non-tumor necrosis factor-based biologic therapies for rheumatoid arthritis: present, future, and insights into pathogenesis

Filipe Seguro Paula & José Delgado Alves

Pages: 1-12

Published online: 07 Dec 2022

AbstractforNon-tumor necrosis factor-based biologic therapies for rheumatoid arthritis: present, future, and insights into pathogenesis | Full Text | References | PDF (260.9 KB)

83 Views
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Open Access

Review Article

Ziv-aflibercept in metastatic colorectal cancer

Anuj Patel & Weijing Sun

Pages: 13-25

Published online: 16 Dec 2013

AbstractforZiv-aflibercept in metastatic colorectal cancer | Full Text | References | PDF (291.7 KB)

127 Views
11 CrossRef citations
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Open Access

Review Article

Therapeutic vaccines and cancer: focus on DPX-0907

Mohan Karkada, Neil L Berinstein & Marc Mansour

Pages: 27-38

Published online: 10 Feb 2014

AbstractforTherapeutic vaccines and cancer: focus on DPX-0907 | Full Text | References | PDF (422.3 KB)

91 Views
21 CrossRef citations
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Open Access

Retraction

Biologic targeting in the treatment of inflammatory bowel diseases [Retraction]

Page: 39

Published online: 31 Jan 2014

CitationforBiologic targeting in the treatment of inflammatory bowel diseases [Retraction] | Full Text | PDF (108.8 KB)

56 Views
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Open Access

Review

Review Article

A critical evaluation of the role of subcutaneous abatacept in the treatment of rheumatoid arthritis: patient considerations

Alvin F Wells, Nicole Jodat & Michael Schiff

Pages: 41-55

Published online: 17 Feb 2014

AbstractforA critical evaluation of the role of subcutaneous abatacept in the treatment of rheumatoid arthritis: patient considerations | Full Text | References | PDF (889.9 KB)

80 Views
1 CrossRef citations
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Open Access

Corrigendum

Correction

Anti-tumor necrosis factor (TNF) drugs for the treatment of psoriatic arthritis: an indirect comparison meta-analysis [Corrigendum]

Pages: 57-58

Published online: 07 Feb 2014

CitationforAnti-tumor necrosis factor (TNF) drugs for the treatment of psoriatic arthritis: an indirect comparison meta-analysis [Corrigendum] | Full Text | PDF (139.2 KB)

82 Views
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Open Access

Hypothesis

Article

Does the cis/trans configuration of peptide bonds in bioactive tripeptides play a role in ACE-1 enzyme inhibition?

Aino Siltari, Riikka Viitanen, Sampo Kukkurainen, Heikki Vapaatalo & Jarkko Valjakka

Pages: 59-65

Published online: 11 Feb 2014

AbstractforDoes the cis/trans configuration of peptide bonds in bioactive tripeptides play a role in ACE-1 enzyme inhibition? | Full Text | References | PDF (878.7 KB)

75 Views
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Open Access

Review

Review Article

Update on the use of systemic biologic agents in the treatment of noninfectious uveitis

Sirichai Pasadhika & James T Rosenbaum

Pages: 67-81

Published online: 15 Feb 2014

AbstractforUpdate on the use of systemic biologic agents in the treatment of noninfectious uveitis | Full Text | References | PDF (324.8 KB)

198 Views
35 CrossRef citations
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Open Access

Review Article

Porcine dermis implants in soft-tissue reconstruction: current status

Neil J Smart, Nicholas Bryan, John A Hunt & Ian R Daniels

Pages: 83-90

Published online: 10 Mar 2014

AbstractforPorcine dermis implants in soft-tissue reconstruction: current status | Full Text | References | PDF (1.6 MB)

89 Views
9 CrossRef citations
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Open Access

Review Article

Targeted therapy for sarcomas

Charles Forscher, Monica Mita & Robert Figlin

Pages: 91-105

Published online: 17 Mar 2014

AbstractforTargeted therapy for sarcomas | Full Text | References | PDF (299 KB)

99 Views
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Open Access

Review Article

Biologics: the role of delivery systems in improved therapy

Nataša Škalko-Basnet

Pages: 107-114

Published online: 19 Mar 2014

AbstractforBiologics: the role of delivery systems in improved therapy | Full Text | References | PDF (192 KB)

402 Views
34 CrossRef citations
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Open Access

Review Article

Advancing personalized care in hemophilia A: ten years’ experience with an advanced category antihemophilic factor prepared using a plasma/albumin-free method

Erik Berntorp, Gerald Spotts, Lisa Patrone & Bruce M Ewenstein

Pages: 115-127

Published online: 05 Apr 2014

AbstractforAdvancing personalized care in hemophilia A: ten years’ experience with an advanced category antihemophilic factor prepared using a plasma/albumin-free method | Full Text | References | PDF (408.4 KB)

82 Views
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Open Access

Review Article

Multikinase inhibitors in the treatment of thyroid cancer: specific role of lenvatinib

Neda Stjepanovic & Jaume Capdevila

Pages: 129-139

Published online: 10 Apr 2014

AbstractforMultikinase inhibitors in the treatment of thyroid cancer: specific role of lenvatinib | Full Text | References | PDF (1.3 MB)

185 Views
19 CrossRef citations
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Open Access

Review Article

Monoclonal antibodies in rheumatoid arthritis: comparative effectiveness of tocilizumab with tumor necrosis factor inhibitors

Toshio Tanaka, Yoshihiro Hishitani & Atsushi Ogata

Pages: 141-153

Published online: 07 Apr 2014

AbstractforMonoclonal antibodies in rheumatoid arthritis: comparative effectiveness of tocilizumab with tumor necrosis factor inhibitors | Full Text | References | PDF (613.1 KB)

170 Views
22 CrossRef citations
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Open Access

Review Article

Epoetin zeta in the management of anemia associated with chronic kidney disease, differential pharmacology and clinical utility

Mary Lynn Davis-Ajami, Jun Wu, Katherine Downton, Emilie Ludeman & Virginia Noxon

Pages: 155-167

Published online: 16 Apr 2014

AbstractforEpoetin zeta in the management of anemia associated with chronic kidney disease, differential pharmacology and clinical utility | Full Text | References | PDF (388.1 KB)

102 Views
4 CrossRef citations
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Open Access

Review Article

Long term efficacy and safety of etanercept in the treatment of psoriasis and psoriatic arthritis

Dario Kivelevitch, Bobbak Mansouri & Alan Menter

Pages: 169-182

Published online: 17 Apr 2014

AbstractforLong term efficacy and safety of etanercept in the treatment of psoriasis and psoriatic arthritis | Full Text | References | PDF (1.1 MB)

171 Views
10 CrossRef citations
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Open Access

Review Article

Clinical and comparative utility of afatinib in non-small cell lung cancer

Manolo D’Arcangelo & Fred R Hirsch

Pages: 183-192

Published online: 23 Apr 2014

AbstractforClinical and comparative utility of afatinib in non-small cell lung cancer | Full Text | References | PDF (273 KB)

93 Views
7 CrossRef citations
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Open Access

Original Research

Article

Anti-TNF therapy in Jordan: a focus on severe infections and tuberculosis

Khaldoon M Alawneh, Mahmoud H Ayesh, Basheer Y Khassawneh, Salwa Shihadeh Saadeh, Mahmoud Smadi & Khaldoun Bashaireh

Pages: 193-198

Published online: 22 Apr 2014

AbstractforAnti-TNF therapy in Jordan: a focus on severe infections and tuberculosis | Full Text | References | PDF (194.8 KB)

65 Views
4 CrossRef citations
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Open Access

Review

Review Article

Plasma membrane coenzyme Q: evidence for a role in autism

Frederick L Crane, Hans Löw, Iris Sun, Placido Navas & Anna Gvozdjáková

Pages: 199-205

Published online: 29 May 2014

AbstractforPlasma membrane coenzyme Q: evidence for a role in autism | Full Text | References | PDF (263.8 KB)

119 Views
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Open Access

Review Article

Golimumab in unresponsive ulcerative colitis

Elisabeth Lippert, Martina Müller & Claudia Ott

Pages: 207-210

Published online: 27 May 2014

AbstractforGolimumab in unresponsive ulcerative colitis | Full Text | References | PDF (262.9 KB)

53 Views
1 CrossRef citations
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Open Access

Review Article

Apoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists

Paulo César Martins Urbano, Vanete Thomaz Soccol & Valderilio Feijó Azevedo

Pages: 211-220

Published online: 31 Jul 2014

AbstractforApoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists | Full Text | References | PDF (605 KB)

74 Views
4 CrossRef citations
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Open Access

Review Article

New product development with the innovative biomolecular sublingual immunotherapy formulations for the management of allergic rhinitis

Franco Frati, Lorenzo Cecchi, Enrico Scala, Erminia Ridolo, Ilaria Dell’Albani, Eleni Makrì, Giovanni Pajno & Cristoforo Incorvaia

Pages: 221-226

Published online: 12 Sep 2014

AbstractforNew product development with the innovative biomolecular sublingual immunotherapy formulations for the management of allergic rhinitis | Full Text | References | PDF (3.3 MB)

82 Views
1 CrossRef citations
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Open Access

Review Article

Botulinum toxin type A products are not interchangeable: a review of the evidence

Mitchell F Brin, Charmaine James & John Maltman

Pages: 227-241

Published online: 06 Oct 2014

AbstractforBotulinum toxin type A products are not interchangeable: a review of the evidence | Full Text | References | PDF (436.3 KB)

740 Views
33 CrossRef citations
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Open Access

Review Article

Resistant mutations in CML and Ph⁺ALL – role of ponatinib

Geoffrey D Miller, Benjamin J Bruno & Carol S Lim

Pages: 243-254

Published online: 20 Oct 2014

AbstractforResistant mutations in CML and Ph⁺ALL – role of ponatinib | Full Text | References | PDF (547 KB)

258 Views
28 CrossRef citations
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Open Access

Review Article

Targeted alpha anticancer therapies: update and future prospects

Barry J Allen, Chen-Yu Huang & Raymond A Clarke

Pages: 255-267

Published online: 10 Nov 2014

AbstractforTargeted alpha anticancer therapies: update and future prospects | Full Text | References | PDF (296.6 KB)

148 Views
18 CrossRef citations
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Open Access

Original Research

Article

Inactivation of chromatin remodeling factors sensitizes cells to selective cytotoxic stress

Miles D Freeman, Tryphon Mazu, Jana S Miles, Selina Darling-Reed & Hernan Flores-Rozas

Pages: 269-280

Published online: 14 Nov 2014

AbstractforInactivation of chromatin remodeling factors sensitizes cells to selective cytotoxic stress | Full Text | References | PDF (2.6 MB)

62 Views
4 CrossRef citations
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Open Access

Review

Review Article

Multikinase inhibitors use in differentiated thyroid carcinoma

Sina Jasim, Levent Ozsari & Mouhammed Amir Habra

Pages: 281-291

Published online: 07 Dec 2022

AbstractforMultikinase inhibitors use in differentiated thyroid carcinoma | Full Text | References | PDF (661.4 KB)

81 Views
8 CrossRef citations
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Open Access

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