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Original Research

An Open-Label Single-Arm, Monocentric Study Assessing the Efficacy and Safety of Natural Pterostilbene (Pterocarpus marsupium) for Skin Brightening and Antiaging Effects

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Pages 105-116 | Published online: 31 Jan 2020

References

  • Silva SAME, Michniak-Kohn B, Leonardi GR. An overview about oxidation in clinical practice of skin aging. An Bras Dermatol. 2017;92(3):367–374. doi:10.1590/abd1806-4841.2017548129186250
  • Ganceviciene R, Liakou AI, Theodoridis A, Makrantonaki E, Zouboulis CC. Skin anti-aging strategies. Dermatoendocrinol. 2012;4(3):308–319. doi:10.4161/derm.2280423467476
  • Zhang S, Duan E. Fighting against skin aging: the way from bench to bedside. Cell Transplant. 2018;27(5):729–738. doi:10.1177/096368971772575529692196
  • Campa M, Baron E. Anti-aging effects of select botanicals: scientific evidence and current trends. Cosmetics. 2018;5(3):54. doi:10.3390/cosmetics5030054
  • Kohl E, Steinbauer J, Landthaler M, Szeimies RM. Skin ageing. J Eur Acad Dermatol Venereol. 2011;2:873–884. doi:10.1111/j.1468-3083.2010.03963.x
  • Concepcion P, Mercado-Saenz S, Perez-Davo A, Gilaberte Y, Gonzalez S, Juarranz A. Environmental stressors on skin aging. Mechanistic insights front. Pharmacol. 2019;9. doi:10.3389/fphar.2019.00759.
  • Datta HS, Paramesh R. Trends in aging and skincare: ayurvedic concepts. J Ayurveda Integr Med. 2010;1(2):110–113. doi:10.4103/0975-9476.6508121836797
  • Mohiuddin AK. Skin lightening & management of hyperpigmentation. Pharma Sci Anal Res J. 2019;2(2):180020.
  • Maurya R, Singh R, Deepak M, Handa SS, Yadav PP, Mishra PK. Constituents of Pterocarpus marsupium: an ayurvedic crude drug. Phytochemistry. 2004;65:915–920. doi:10.1016/j.phytochem.2004.01.02115081294
  • Tsai HY, Ho CT, Chen YK. Biological actions and molecular effects of resveratrol, pterostilbene, and 3ʹ-hydroxypterostilbene. J Food Drug Anal. 2017;25:134–147. doi:10.1016/j.jfda.2016.07.00428911531
  • McCormack D, McFadden D. A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev. 2013;2013:575482.23691264
  • Estrela JM, Ortega A, Mena S, Rodriguez ML, Asensi M. Pterostilbene: biomedical applications. Crit Rev Clin Lab Sci. 2013;50(3):65–78. doi:10.3109/10408363.2013.80518223808710
  • Chan EWC, Wong CW, Tan YH, Foo JPY, Wong SK, Chan HT. Resveratrol and pterostilbene: a comparative overview of their chemistry, biosynthesis, plant sources, and pharmacological properties. J Appl Pharm Sci. 2019;9(7):124–129. doi:10.7324/JAPS.2019.90717
  • Tiwari M, Sharma M, Khare HN. Chemical constituents and medicinal uses of Pterocarpus marsupium roxb. Flora Fauna. 2015;21(1):5559.
  • Pinto M, Moraes CT. Mechanisms linking mtDNA damage and aging. Free Radic Biol Med. 2015;85:250–258. doi:10.1016/j.freeradbiomed.2015.05.00525979659
  • Li H, Jiang N, Liang B, et al. Pterostilbene protects against UVB-induced photo-damage through a phosphatidylinositol-3-kinase-dependent Nrf2/ARE pathway in human keratinocytes. Redox Report. 2017;22(6):501–507. doi:10.1080/13510002.2017.132991728532341
  • Sirerol JA, Feddi F, Salvador M, Rodriguez ML. Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis. Free Radical Biol Med. 2015;85:1–11. doi:10.1155/2016/312895125845487
  • Li YR, Li S, Lin C. Effect of resveratrol and pterostilbene on aging and longevity. BioFactors. 2018;44:69–82. doi:10.1002/biof.140029210129
  • Siegrist W, Eberle AN. In situ melanin assay for MSH using mouse B16 melanoma cells in culture. Anal Biochem. 1986;159(1):191–197. doi:10.1016/0003-2697(86)90327-13812999
  • Matsuda H, Nakashima S, Oda Y, Nakamura S, Yoshikawa M. Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cells. Bioorg Med Chem. 2009;17(16):6048–6053. doi:10.1016/j.bmc.2009.06.05719615910
  • Binic V, Lazarevic V, Ljubenovic M, Mojsa J, Sokolovic D. Skin ageing: natural weapons and strategies. Evidence-Based Complementary Altern Med. 2013;2. doi:10.1155/2013/827248
  • Baswan SM, Leverett J, Pawelek J. Clinical evaluation of the lightening effect of cytidine on hyperpigmented skin. J Cosmet Dermatol. 2018;18:1–8. doi:10.1111/jocd.12784
  • Yim S, Lee J, Jo H, Scholten Willingham J, Nicoll R, Baswan SM. Chrysanthemum morifolium extract andascorbic acid-2-glucoside (AA2G) blend inhibits UVA-induced delayed Cyclobutane PyrimidineDimer (CPD) production in melanocytes. Clin Cosmet Investig Dermatol. 2019;12:823–832. doi:10.2147/CCID.S223802
  • Chiou YS1, Tsai ML, Nagabhushanam K, et al. Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM) induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2) mediated antioxidant signaling pathway. J Agric Food Chem. 2011; 23;59(6):2725–2733. doi:10.1021/jf200010321355597
  • Yeo SC, Ho PC, Lin HS. Pharmacokinetics of pterostilbene in Sprague-Dawley rats: the impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability. Mol Nutr Food Res. 2013;57(6):1015–1025. doi:10.1002/mnfr.20120065123417986
  • Yang Y, Fan C, Wang B, et al. Pterostilbene attenuates high glucose-induced oxidative injury in hippocampal neuronal cells by activating nuclear factor erythroid 2-related factor 2. Biochim Biophys Acta. 2017;1863:827–837. doi:10.1016/j.bbadis.2017.01.005
  • Li J, Deng R, Hua ZL, Lu F. Blueberry component pterostilbene protects corneal epithelial cells from inflammation via anti-oxidative pathway. Sci Rep. 2016;6:19408. doi:10.1038/srep1940826762881
  • Choo QY, Yeo SCM, Ho P, Tanaka Y, Lin HS. Pterostilbene surpassed resveratrol for anti-inflammatory application: potencyconsideration and pharmacokinetics perspective. J Funct Foods. 2014;11:352–362. doi:10.1016/j.jff.2014.10.018
  • Xue EX, Lin JP, Zhang Y, et al. Pterostilbene inhibits inflammation and ROS production in chondrocytes by activating Nrf2 pathway. Oncotarget. 2017;8:41988–42000. doi:10.18632/oncotarget.1671628410217
  • Hwang ESY, Park CS, Yin HT, Kim YM, Yi TH. Anti-aging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin. J Ginseng Res. 2016;41(1). doi:10.1016/j.jgr.2016.01.001
  • Pena Ferreira MR, Costa PC, Bahia FM. Efficacy of anti-wrinkle products in skin surface appearance: a comparative study using non-invasive methods. Skin Res Technol. 2010;2:189–194. doi:10.1111/j.1600-0846.2010.00458.x
  • Langton AK, Sherratt MJ, Griffiths C, Watson RE. A new wrinkle on old skin: the role of elastic fibers in skin ageing. Int J Cosmet Sci. 2010;32(5):330–339. doi:10.1111/j.1468-2494.2010.00574.x20572890
  • Poljšak B, Dahmane R. Free radicals and extrinsic skin aging. Dermatol Res Pract. 2012;135206. doi:10.1155/2012/13520622505880
  • Verdier-Sevrain S. Effect of estrogens on skin aging and the potential role of selective estrogen receptor modulators. Climacteric. 2007;10:289–297. doi:10.1080/1369713070146715717653955
  • Linming F, Wei H, Anqi L, et al. Comparison of two skin imaging analysis instruments: the VISIA® from canfield vs the ANTERA3D®CS from Miravex. Skin Res Technol. 2018;24:3–8. doi:10.1111/srt.1238128585335
  • Costin GE. Hearing Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J. 2007;21:976–994. doi:10.1096/fj.06-6649rev17242160