158
Views
6
CrossRef citations to date
0
Altmetric
Review

Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly

, , &
Pages 27-35 | Published online: 22 Dec 2010

References

  • Heart disease and stroke statistics – 2010 update. Available at: http://www.americanheart.org/presenter.jhtml?identifier=3018163. Accessed 2010 Nov 22.
  • GopalABudoffMJCoronary calcium scanning in geriatric cardiologyAm J Geriatr Cardiol20071636937517975335
  • Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)JAMA20012852486249711368702
  • AkosahKOSchaperACogbillCPreventing myocardial infarction in the young adult in the first place: How do the National Cholesterol Education Panel III guidelines performJ Am Coll Cardiol2003411475147912742284
  • MichosEDNasirKBraunsteinJBFramingham risk equation underestimates subclinical atherosclerosis risk in asymptomatic womenAtherosclerosis200618420120615907856
  • DeMazumderDHasanRKBlumenthalRSMichosEDJonesSShould statin therapy be allocated on the basis of global risk or on the basis of randomized trial evidenceAm J Cardiol201010690590920816135
  • AlexanderKPNewbyLKCannonCPAcute coronary care in the elderly, Part I: Non-ST-segment-elevation acute coronary syndromes: A scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology, in collaboration with the Society of Geriatric CardiologyCirculation20071152549256917502590
  • KellerNMFeitFCoronary artery disease in the geriatric populationProg Cardiovasc Dis1996384074188604446
  • HanonOCoronary artery disease in patients 80 years and olderRev Prat200858156170 French.
  • DavidsonMHMakiKCPearsonTAResults of the National Cholesterol Education (NCEP) Program Evaluation ProjecT Utilizing Novel E-Technology (NEPTUNE) II Survey and implications for treatment under the recent NCEP Writing Group recommendationsAm J Cardiol20059655656316098311
  • RidkerPMDanielsonEFonsecaFAfor the JUPITER study groupRosuvastatin to prevent vascular events in men and women with elevated C-reactive proteinN Engl J Med20083592195220718997196
  • KapurNKRosuvastatin: A highly potent statin for the prevention and management of coronary artery diseaseExpert Rev Cardiovasc Ther2007516117517338662
  • YildirirAMuderrisogluHNon-lipid effects of statins: Emerging new indicationsCurr Vasc Pharmacol2004230931815320810
  • JonesPHDavidsonMHSteinEASTELLAR Study GroupComparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR trial)Am J Cardiol20039215216012860216
  • SchusterHBarterPJStenderSEffective Reductions in Cholesterol Using Rosuvastatin Therapy I study groupEffects of switching statins on achievement of lipid goals: Measuring Effective Reductions in Cholesterol Using Rosuvastatin Therapy (MERCURY I)Am Heart J200414770571315077101
  • BallantyneCMBertolamiMHernandez GarciaHRAchieving LDL cholesterol, non-HDL cholesterol, and apolipoprotein B target levels in high-risk patient: Measuring Effective Reductions in Cholesterol Using Rosuvastatin therapy (MERCURY II)Am Heart J2006151975.e1979.e116644314
  • RidkerPMDanielsonEFonsecaFAReduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: A prospective study of the JUPITER trialLancet20093731175118219329177
  • LaRosaJCGrundySMWatersDDfor the Treating to New Targets (TNT) InvestigatorsIntensive lipid lowering with atorvastatin in patients with stable coronary diseaseN Engl J Med20053521425143515755765
  • CannonCPBraunwaldEMcCabeCHfor the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 Investigators (PROVE-IT TIMI 22)Intensive versus moderate lipid lowering with statins after acute coronary syndromesN Engl J Med20043501495150415007110
  • PedersonTRCaterNBFaergemanOComparison of atorvastatin 80 mg/day vs simvastatin 20–40 mg/day on frequency of cardiovascular events late (five years) after acute myocardial infarction (from the Incremental Decrease in End Points through Aggressive Lipid Lowering [IDEAL] trial)Am J Cardiol201010635435920643245
  • TzengTBSchneckDWBirminghamBKPopulation pharmacokinetics of rosuvastatin: Implications of renal impairment, race, and dyslipidaemiaCurr Med Res Opin2008242575258518674408
  • Clofibrate and niacin in coronary heart diseaseJAMA19752313603811088963
  • The Scandinavian Simvastatin Survival Study GroupRandomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)Lancet1994344138313897968073
  • SacksFMPfefferMAMoyeLAThe effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial InvestigatorsN Engl J Med1996335100110098801446
  • The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study GroupPrevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levelsN Engl J Med1998339134913579841303
  • Heart Protection Study Collaborative GroupMRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20536 high-risk individuals a randomized placebo controlled trialLancet200236072212114036
  • SheperdJBlauwGJMurphyMBfor the PROSPER study groupPravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomized controlled trialLancet20023601623163012457784
  • BrugtsJJYetginTHoeksSEThe benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: Meta-analysis of randomized controlled trialsBMJ2009338b237619567909
  • DeedwaniaPStonePHBairey MerzCNEffect of intensive vs moderate lipid-lowering therapy on myocardial ischemia in older patients with coronary heart disease: Results of the Study Assessing Goals in the Elderly (SAGE)Circulation200711670070717664372
  • GransboKMelanderOWallentinLCardiovascular and cancer mortality in very elderly post-myocardial infarction patients receiving statin treatmentJ Am Coll Cardiol2010551362136920338498
  • ShepherdJCobbeSMFordIfor the West of Scotland Coronary Prevention Study Group (WOSCOPS)Prevention of coronary heart disease with pravastatin in men with hypercholesterolemiaN Engl J Med1995333130113077566020
  • NakamuraHArakawaKItakuraHfor the MEGA groupPrimary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): A prospective randomized controlled trialLancet20063681155116317011942
  • DownsJRClearfieldMWeisSPrimary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of (AFCAPS/TexCAPS) Air Force/Texas Coronary Atherosclerosis Prevention StudyJAMA1998279161516229613910
  • SeverPSDahlofBPoulterNRfor the ASCOT investigatorsPrevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial – Lipid Lowering Arm (ASCOT-LLA): A multicenter randomized controlled trialLancet20033611149115812686036
  • GlynnRJDanielsonEFonsecaFAA randomized trial of rosuvastatin in the prevention of venous thromboembolismN Engl J Med20093601851186119329822
  • GlynnRJKoenigWNordestgaardBGSheperdJRidkerPMRosuvastatin for primary prevention in older persons with elevated C-reactive protein and low to average low density lipoprotein cholesterol levels: Exploratory analysis of a randomized trialAnn Intern Med201015248849620404379
  • LewingtonSWhitlockGClarkeRProspective Studies Collaboration. Blood cholesterol and vascular mortality by age, sex, and blood pressure: A meta-analysis of individual data from 61 prospective studies with 55,000 vascular deathsLancet20073701829183918061058
  • NarlaVBlahaMJBlumenthalRSMichosEDThe JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: Perspectives, outcomes, and consequencesVasc Health Risk Manag200951033104220057896
  • BasslerDBrielMMontoriVMStopping randomized trials early for benefit and estimation of treatment effects: Systematic review and meta-regression analysisJAMA20103031180118720332404
  • RidkerPMGlynnRJThe JUPITER trial: Responding to the criticsAm J Cardiol20101061351135621029837
  • MichosEDBlumenthalRSPrevalence of low low-density lipoprotein cholesterol with elevated high sensitivity C-reactive protein in the USJ Am Coll Cardiol20095393193519281922
  • FellströmBCJardineAGSchmiederRERosuvastatin and cardiovascular events in patients undergoing hemodialysisN Engl J Med20093601395140719332456
  • FoleyRNMurrayAMLiSChronic kidney disease and the risk of cardiovascular disease, renal replacement, and death in the United States Medicare population, 1998 to 1999J Am Soc Nephrol20051648949515590763
  • KjekshusJApetreiEBarriosVfor the CORONA GroupRosuvastatin in older patients with systolic heart failureN Engl J Med20073572248226117984166
  • McMurrayJJKjekshusJGullestadLfor the CORONA Study GroupEffects of statin therapy according to plasma high-sensitivity C-reactive protein concentration in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): A retrospective analysisCirculation20091202188219619917888
  • LorgellyPKBriggsAHWedelHfor the CORONA Study GroupAn economic evaluation of rosuvastatin treatment in systolic heart failure: Evidence from the CORONA trialEur J Heart Fail201012667420023047
  • LemaitreRNFurbergCDNewmanABTime trends in the use of cholesterol-lowering agents in older adults: The Cardiovascular Health StudyArch Intern Med1998158176117689738605
  • WhincupPHEmbersonJRLennonLWalkerMPapacostaOThomsonALow prevalence of lipid lowering drug use in older men with established coronary heart diseaseHeart200288252912067936
  • KoDTMamdaniMAlterDALipid-lowering therapy with statins in high risk elderly patients: The treatment-risk paradoxJAMA20042911864187015100205
  • GnaviRMigliardiADemariaMPetrelliACaprioglioACostaGStatins prescribing for the secondary prevention of ischaemic heart disease in Torino, Italy. A case of ageism and social inequalitiesEur J Public Health20071749249617303583
  • NiskaRHanBStatins for secondary cardiovascular disease prevention for older primary care patientsJ Natl Med Assoc200910170571019634592
  • KrumholzHMMurilloJEChenJThrombolytic therapy for eligible elderly patients with acute myocardial infarctionJAMA1997277168316889169894
  • RochonPAAndersonGMTuJVUse of beta-blocker therapy in older patients after acute myocardial infarction in OntarioCMAJ19991611403140810906894
  • SattarNPreissDMurrayHMStatins and the risk of incident diabetes: A collaborative meta-analysis of randomized statin trialsLancet201037573574220167359
  • AthyrosVGTziomalosKKaragiannisAMikhailidisDPLipid-lowering agents and new onset diabetes mellitusExpert Opin Pharmacother2010111965197020486831
  • RobinsonJGBakrisGTornerJStoneNJWallaceRIs it time for a cardiovascular primary prevention trial in the elderlyStroke20073844145017194877