Evaluation of a 2-aminoimidazole variant as adjuvant treatment for dermal bacterial infections

References

• LipskyBADiabetic foot infections: current treatment and delaying the ‘post-antibiotic era’Diabetes Metab Res Rev201632Suppl 124625326452233
   PubMed Web of Science ®Google Scholar
• StewartPSCostertonJWAntibiotic resistance of bacteria in biofilmsLancet2001358927613513811463434
   PubMed Web of Science ®Google Scholar
• PercivalSLHillKEMalicSThomasDWWilliamsDWAntimicrobial tolerance and the significance of persister cells in recalcitrant chronic wound biofilmsWound Repair Regen20111911921235682
   PubMed Web of Science ®Google Scholar
• ForemanAHoltappelsGPsaltisAJAdaptive immune responses in Staphylococcus aureus biofilm-associated chronic rhinosinusitisAllergy201166111449145621834937
   PubMed Web of Science ®Google Scholar
• RasmussenTBGivskovMQuorum-sensing inhibitors as anti-pathogenic drugsInt J Med Microbiol20062962–3149161
   PubMed Web of Science ®Google Scholar
• CostertonJWStewartPSGreenbergEPBacterial biofilms: a common cause of persistent infectionsScience199928454181318132210334980
   PubMed Web of Science ®Google Scholar
• DonlanRMCostertonJWBiofilms: survival mechanisms of clinically relevant microorganismsClin Microbiol Rev200215216719311932229
   PubMed Web of Science ®Google Scholar
• MahTFO’TooleGAMechanisms of biofilm resistance to antimicrobial agentsTrends Microbiol200191343911166241
   PubMed Web of Science ®Google Scholar
• BoucherRCNew concepts of the pathogenesis of cystic fibrosis lung diseaseEur Respir J200423114615814738247
   PubMed Web of Science ®Google Scholar
• YoonSSHenniganRFHilliardGMPseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesisDev Cell20023459360312408810
   PubMed Web of Science ®Google Scholar
• CostertonJWCystic fibrosis pathogenesis and the role of biofilms in persistent infectionTrends Microbiol200192505211173226
   PubMed Web of Science ®Google Scholar
• CiofuOTolker-NielsenTJensenPØWangHHøibyNAntimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patientsAdv Drug Deliv Rev20158572325477303
   PubMed Web of Science ®Google Scholar
• BjarnsholtTKirketerp-MøllerKJensenPØWhy chronic wounds will not heal: a novel hypothesisWound Repair Regen200816121018211573
   PubMed Web of Science ®Google Scholar
• BiondaNFleemanRMde la Fuente-NúñezCIdentification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activitiesEur J Med Chem201610835436326703794
   PubMed Web of Science ®Google Scholar
• DowdSESunYSecorPRSurvey of bacterial diversity in chronic wounds using pyrosequencing, DGGE, and full ribosome shotgun sequencingBMC Microbiol200884318325110
   PubMed Web of Science ®Google Scholar
• JamesGASwoggerEWolcottRBiofilms in chronic woundsWound Repair Regen2008161374418086294
   PubMed Web of Science ®Google Scholar
• DantesRMuYBelflowerRNational burden of invasive methicillin-resistant Staphylococcus aureus infections, United States, 2011JAMA Intern Med2013173211970197824043270
   PubMed Web of Science ®Google Scholar
• KochanekKDMurphySLXuJDeaths: final data for 2011Natl Vital Stat Rep20156331120
   Google Scholar
• CowanLJStechmillerJKPhillipsPYangQSchultzGChronic Wounds, Biofilms and Use of Medicinal LarvaeUlcers2013 Article ID 4870247201310.1155/2013/487024
   Google Scholar
• PetersGLocciRPulvererGMicrobial colonization of prosthetic devices. II. Scanning electron microscopy of naturally infected intravenous cathetersZentralbl Bakteriol Mikrobiol Hyg B198117352932996792814
   PubMedGoogle Scholar
• VillersDEspazeECoste-BurelMNosocomial Acinetobacter baumannii infections: microbiological and clinical epidemiologyAnn Intern Med199812931821899696725
   PubMed Web of Science ®Google Scholar
• Hall-StoodleyLCostertonJWStoodleyPBacterial biofilms: from the natural environment to infectious diseasesNat Rev Microbiol2004229510815040259
   PubMed Web of Science ®Google Scholar
• KirkerKRSecorPRJamesGAFleckmanPOlerudJEStewartPSLoss of viability and induction of apoptosis in human keratinocytes exposed to Staphylococcus aureus biofilms in vitroWound Repair Regen200917569069919671124
   PubMed Web of Science ®Google Scholar
• Jeffery MaranoRJane WallaceHWijeratneDWilliam FearMSan WongHO’HandleyRSecreted biofilm factors adversely affect cellular wound healing responses in vitroSci Rep201551329626278131
   PubMed Web of Science ®Google Scholar
• Infectious Diseases Society of AmericaSpellbergBBlaserMCombating antimicrobial resistance: policy recommendations to save livesClin Infect Dis201152Suppl 5S397S42821474585
   PubMed Web of Science ®Google Scholar
• ClatworthyAEPiersonEHungDTTargeting virulence: a new paradigm for antimicrobial therapyNat Chem Biol20073954154817710100
   PubMed Web of Science ®Google Scholar
• NeuHCThe crisis in antibiotic resistanceScience19922575073106410731509257
   PubMed Web of Science ®Google Scholar
• LiuYYWangYWalshTREmergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological studyLancet Infect Dis201616216116826603172
   PubMed Web of Science ®Google Scholar
• LeeJYHowdenBPVancomycin in the treatment of methicillin-resistant Staphylococcus aureus – a clinician’s guide to the science informing current practiceExpert Rev Anti Infect Ther201513785586925947636
   PubMed Web of Science ®Google Scholar
• RogersSAHuigensRWCavanaghJMelanderCSynergistic effects between conventional antibiotics and 2-aminoimidazole-derived antibiofilm agentsAntimicrob Agents Chemother20105452112211820211901
   PubMed Web of Science ®Google Scholar
• BallardTERichardsJJWolfeALMelanderCSynthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: a structure-activity relationship studyChemistry20081434107451076118942682
   PubMed Web of Science ®Google Scholar
• RichardsJJBallardTEMelanderCInhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analoguesOrg Biomol Chem2008681356136318385842
   PubMed Web of Science ®Google Scholar
• RichardsJJHuigensRWIIIBallardTEBassoACavanaghJMelanderCInhibition and dispersion of proteobacterial biofilmsChem Commun20081416981700
   Web of Science ®Google Scholar
• KeiferPASchwartzREKokerMESHughesRGRittschofDRinehartKLBioactive bromopyrrole metabolites from the Caribbean sponge Agelas coniferaJ Org Chem199156929652975
   Web of Science ®Google Scholar
• YamadaAKitamuraHYamaguchiKDevelopment of chemical substances regulating biofilm formationB Chem Soc Japan1997701230613069
   Web of Science ®Google Scholar
• ThompsonRJBobayBGStoweSDIdentification of BfmR, a response regulator involved in biofilm development, as a target for a 2-aminoimidazole-based antibiofilm agentBiochemistry201251499776977823186243
   PubMed Web of Science ®Google Scholar
• WestAHStockAMHistidine kinases and response regulator proteins in two-component signaling systemsTrends Biochem Sci200126636937611406410
   PubMed Web of Science ®Google Scholar
• NarayananAKumarSEvrardANPaulLNYernoolDAAn asymmetric heterodomain interface stabilizes a response regulator-DNA complexNat Commun20145328224526190
   PubMed Web of Science ®Google Scholar
• LouYCWengTHLiYCStructure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNANat Commun20156883826564787
   PubMed Web of Science ®Google Scholar
• MarisAEKaczor-GrzeskowiakMMaZKopkaMLGunsalusRPDickersonREPrimary and secondary modes of DNA recognition by the NarL two-component response regulatorBiochemistry20054444145381455216262254
   PubMed Web of Science ®Google Scholar
• StockAMRobinsonVLGoudreauPNTwo-component signal transductionAnnu Rev Biochem20006918321510966457
   PubMed Web of Science ®Google Scholar
• BeierDGrossRRegulation of bacterial virulence by two-component systemsCurr Opin Microbiol20069214315216481212
   PubMed Web of Science ®Google Scholar
• StephensonKHochJAVirulence- and antibiotic resistance-associated two-component signal transduction systems of Gram-positive pathogenic bacteria as targets for antimicrobial therapyPharmacol Ther2002932–329330512191621
   PubMed Web of Science ®Google Scholar
• KurodaMKuwahara-AraiKHiramatsuKIdentification of the up- and down-regulated genes in vancomycin-resistant Staphylococcus aureus strains Mu3 and Mu50 by cDNA differential hybridization methodBiochem Biophys Res Commun2000269248549010708580
   PubMed Web of Science ®Google Scholar
• BelchevaAGolemi-KotraDA close-up view of the VraSR two-component system. A mediator of Staphylococcus aureus response to cell wall damageJ Biol Chem200828318123541236418326495
   PubMed Web of Science ®Google Scholar
• StephensonKHochJADeveloping inhibitors to selectively target two-component and phosphorelay signal transduction systems of pathogenic microorganismsCurr Med Chem200411676577315032730
   PubMed Web of Science ®Google Scholar
• StephensonKHochJATwo-component and phosphorelay signal-transduction systems as therapeutic targetsCurr Opin Pharmacol20022550751212324251
   PubMed Web of Science ®Google Scholar
• BarrettJFGoldschmidtRMLawrenceLEAntibacterial agents that inhibit two-component signal transduction systemsProc Natl Acad Sci U S A1998959531753229560273
   PubMed Web of Science ®Google Scholar
• StephensonKHochJAHistidine kinase-mediated signal transduction systems of pathogenic microorganisms as targets for therapeutic interventionCurr Drug Targets Infect Disord20022323524612462127
   PubMedGoogle Scholar
• GotohYEguchiYWatanabeTOkamotoSDoiAUtsumiRTwo-component signal transduction as potential drug targets in pathogenic bacteriaCurr Opin Microbiol201013223223920138000
   PubMed Web of Science ®Google Scholar
• MatsushitaMJandaKDHistidine kinases as targets for new antimicrobial agentsBioorg Med Chem200210485586711836091
   PubMed Web of Science ®Google Scholar
• DesrosiersMMynttiMJamesGMethods for removing bacterial biofilms: in vitro study using clinical chronic rhinosinusitis specimensAm J Rhinol200721552753217883887
   PubMedGoogle Scholar
• XuKDStewartPSXiaFHuangCTMcFetersGASpatial physiological heterogeneity in Pseudomonas aeruginosa biofilm is determined by oxygen availabilityAppl Environ Microbiol19986410403540399758837
   PubMed Web of Science ®Google Scholar
• FukanoYKnowlesNGUsuiMLCharacterization of an in vitro model for evaluating the interface between skin and percutaneous biomaterialsWound Repair Regen200614448449116939578
   PubMed Web of Science ®Google Scholar
• DraizeJDermal toxicityAppraisal of the Safety of Chemicals in Foods, Drugs and CosmeticsAustin, TXAssociation of Food and Drug Officials, US, Texas State Department of health19594659
   Google Scholar
• ASTM E2647-08 Standard Test Method for Quantification of a Pseudomonas aeruginosa Biofilm Grown Using a Drip Flow Biofilm Reactor with Low Shear and Continuous flowASTM InternationalWest Conshohocken, PA2008
   Google Scholar
• Buckingham-MeyerKGoeresDMHamiltonMAComparative evaluation of biofilm disinfectant efficacy testsJ Microbiol Methods200770223624417524505
   PubMed Web of Science ®Google Scholar
• GoeresDMHamiltonMABeckNAA method for growing a biofilm under low shear at the air–liquid interface using the drip flow biofilm reactorNat Protoc20094578378819528953
   PubMed Web of Science ®Google Scholar
• CurtinJJDonlanRMUsing bacteriophages to reduce formation of catheter-associated biofilms by Staphylococcus epidermidisAntimicrob Agents Chemother20065041268127516569839
   PubMed Web of Science ®Google Scholar
• Pérez-DíazMAlvarado-GomezEMagaña-AquinoMAnti-biofilm activity of chitosan gels formulated with silver nanoparticles and their cytotoxic effect on human fibroblastsMater Sci Eng C Mater Biol Appl20166031732326706536
   PubMed Web of Science ®Google Scholar
• KirkerKRJamesGAFleckmanPOlerudJEStewartPSDifferential effects of planktonic and biofilm MRSA on human fibroblastsWound Repair Regen201220225326122332802
   PubMed Web of Science ®Google Scholar
• GodinBTouitouETransdermal skin delivery: predictions for humans from in vivo, ex vivo and animal modelsAdv Drug Deliv Rev200759111152116117889400
   PubMed Web of Science ®Google Scholar
• LebeauxDChauhanARenduelesOBeloinCFrom in vitro to in vivo models of bacterial biofilm-related infectionsPathogens20132228835625437038
   PubMedGoogle Scholar