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Review

Update in treatment of uveitic macular edema

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Pages 667-680 | Published online: 19 Feb 2019

References

  • LardenoyeCWvan KooijBRothovaAImpact of macular edema on visual acuity in uveitisOphthalmology200611381446144916877081
  • GritzDCWongIGIncidence and prevalence of uveitis in northern California; the Northern California Epidemiology of Uveitis StudyOphthalmology2004111349150015019324
  • SuhlerEBLloydMJChoiDRosenbaumJTAustinDFIncidence and prevalence of uveitis in Veterans Affairs Medical Centers of the Pacific NorthwestAm J Ophthalmol20081466890.e8896.e819027424
  • AcharyaNRThamVMEsterbergEIncidence and prevalence of uveitis: results from the Pacific ocular inflammation studyJAMA Ophthalmol2013131111405141224008391
  • MiserocchiEFogliatoGModoratiGBandelloFReview on the worldwide epidemiology of uveitisEur J Ophthalmol201323570571723661536
  • de SmetMDTaylorSRBodaghiBUnderstanding uveitis: the impact of research on visual outcomesProg Retin Eye Res201130645247021807112
  • FardeauCChampionEMassambaNLehoangPOEdème maculaire Au cours des uvéites [Uveitic macular edema]J Fr Ophtalmol20153817481 French25547721
  • RothovaASuttorp-van SchultenMSAFrits TreffersWKijlstraACauses and frequency of blindness in patients with intraocular inflammatory diseaseBr J Ophthalmol19968043323368703885
  • Suttorp-SchultenMSARothovaAThe possible impact of uveitis in blindness: a literature surveyBr J Ophthalmol19968098448488962842
  • RothovaAInflammatory cystoid macular edemaCurr Opin Ophthalmol200718648749218163001
  • FardeauCChampionEMassambaNLehoangPUveitic macular edemaEye (Lond)201630101277129227256304
  • DurraniOMTehraniNNMarrJEMoradiPStavrouPMurrayPIDuration, and causes of visual loss in uveitisBr J Ophthalmol20048891159116215317708
  • GassJDNortonEWCystoid macular edema and papilledema following cataract extraction: a fluorescein fundoscopic and angiographic studyArch Ophthalmol19667656466615955948
  • StaurenghiGde PoloLPellegriniMMacular edema. Diagnosis and detectionDev Ophthalmol201047274820703042
  • Ossewaarde-van NorelARothovaAImaging methods for inflammatory macular edemaInt Ophthalmol Clin2012524556622954929
  • SkondraDHunterRPapakostasTDVavvasDGNear infrared autofluorescence imaging of retinal diseasesSemin Ophthalmol2012275–620220823163277
  • KempenJHSugarEAJaffeGJFluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edemaOphthalmology201312091852185923706700
  • KozakIMorrisonVLClarkTMDiscrepancy between fluorescein angiography and optical coherence tomography in detection of macular diseaseRetina200828453854418398354
  • HoweLStanfordMGrahamEMarshallJIndocyanine green angiography in inflammatory eye diseaseEye199812576176710070505
  • RoeselMHeinzCDietzelMSpitalGHenschelAHeiligenhausAFundus autofluorescence and spectral domain optical coherence tomography in uveitic macular edemaGraefes Arch Clin Exp Ophthalmol2009247121685168919669782
  • RoeselMHeimesBHeinzCHenschelASpitalGHeiligenhausAComparison of retinal thickness and fundus-related microperimetry with visual acuity in uveitic macular oedemaActa Ophthalmol201189653353720003108
  • KempenJHAltaweelMMHolbrookJTJabsDALouisTASugarEAThorneJEMulticenter Uveitis Steroid Treatment (MUST) Trial Research Group, Writing CommitteeRandomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: The Multicenter Uveitis Steroid Treatment TrialOphthalmology2011118101916192621840602
  • SenHNVitaleSGangaputraSSPeriocular corticosteroid injections in uveitis: effects and complicationsOphthalmology2014121112275228625017415
  • LowderCBelfortRLightmanSDexamethasone intravitreal implant for noninfectious intermediate or posterior uveitisArch Ophthalmol2011129554510
  • SheppardJDToyosMMKempenJHKaurPFosterCSDifluprednate 0.05% versus prednisolone acetate 1% for endogenous anterior uveitis: a phase III, multicenter, randomized studyInvestig Ophthalmol Vis Sci20145552993300224677110
  • TajikaTWakiMTsuzukiMKidaTSakakiHPharmacokinetic features of difluprednate ophthalmic emulsion in rabbits as determined by glucocorticoid receptor-binding bioassayJ Ocul Pharmacol Ther2011271293421182429
  • SymesRJForooghianFTopical difluprednate monotherapy for uveitic macular edemaCan J Ophthalmol2016511474926874159
  • SchallhornJMNiemeyerKMBrowneENChhetriPAcharyaNRDifluprednate for the treatment of uveitic cystoid macular edemaAm J Ophthalmol2018191142229580977
  • SlabaughMAHerlihyEOngchinSvan GelderRNEfficacy and potential complications of difluprednate use for pediatric uveitisAm J Ophthalmol2012153593293822265149
  • FeilerDLSrivastavaSKPichiFBenaJLowderCYResolution of noninfectious uveitic cystoid macular edema with topical difluprednateRetina201737584485027529841
  • JermakCMDellacroceJTHeffezJPeymanGATriamcinolone acetonide in ocular therapeuticsSurv Ophthalmol200752550352217719372
  • LederHAJabsDAGalorADunnJPThorneJEPeriocular triamcinolone acetonide injections for cystoid macular edema complicating noninfectious uveitisAm J Ophthalmol2011152344144821652023
  • IwaoKInataniMKawajiTKogaTMawatariYTaniharaHFrequency and risk factors for intraocular pressure elevation after posterior sub-Tenon capsule triamcinolone acetonide injectionJ Glaucoma200716225125617473740
  • FerrantePRamseyABunceCLightmanSClinical trial to compare efficacy and side-effects of injection of posterior sub-Tenon triamcinolone versus orbital floor methylprednisolone in the management of posterior uveitisClin Exp Ophthalmol200432656356815575824
  • KokHLauCMaycockNMcCluskeyPLightmanSOutcome of intravitreal triamcinolone in uveitisOphthalmology2005112111916.e11916.e716171868
  • AndroudiSLetkoEMeniconiMPapadakiTAhmedMFosterCSSafety and efficacy of intravitreal triamcinolone acetonide for uveitic macular edemaOcul Immunol Inflamm2005132–320521216019680
  • AngunawelaRIHeatleyCJWilliamsonTHIntravitreal triamcinalone acetonide for refractory uveitic cystoid macular oedema: long-term management and outcomeActa Ophthalmol Scand200583559559916187999
  • YoungSLarkinGBranleyMLightmanSSafety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitisClin Exp Ophthalmol20012912611272779
  • SallamAComerRMChangJHShort-term safety and efficacy of intravitreal triamcinolone acetonide for uveitic macular edema in childrenArch Ophthalmol2008126220018268210
  • SallamATaylorSRJHabot-WilnerZRepeat intravitreal triamcinolone acetonide injections in uveitic macular oedemaActa Ophthalmol2012904e323e32521914149
  • ShinJYYuHGIntravitreal triamcinolone injection for uveitic macular edema: a randomized clinical studyOcul Immunol Inflamm201523643043626308286
  • RoeselMGutfleischMHeinzCHeimesBZurek-ImhoffBHeiligenhausAIntravitreal and orbital floor triamcinolone acetonide injections in noninfectious uveitis: a comparative studyOphthalmic Res2009422818619478546
  • AdánAPelegrínLReyADexamethasone intravitreal implant for treatment of uveitic persistent cystoid macular edema in vitrectomized patientsRetina20133371435144023514796
  • BezatisASpitalGHöhnFFunctional and anatomical results after a single intravitreal Ozurdex injection in retinal vein occlusion: a 6-month follow-up – the solo studyActa Ophthalmol2013915e340e34723638803
  • TsangACVirgiliGAbtahiMGottliebCCIntravitreal dexamethasone implant for the treatment of macular edema in chronic noninfectious uveitisOcul Immunol Inflamm201725568569227191685
  • CaoJHMulvahillMZhangLJoondephBCDaceyMSDexamethasone intravitreal implant in the treatment of persistent uveitic macular edema in the absence of active inflammationOphthalmology2014121101871187624907061
  • LamWCAlbianiDAYoganathanPReal-world assessment of intravitreal dexamethasone implant (0.7 mg) in patients with macular edema: the chrome studyClin Ophthalmol201591255126826203215
  • ChinHSParkTSMoonYSOhJHDifference in clearance of intra-vitreal triamcinolone acetonide between vitrectomized and nonvitrectomized eyesRetina200525555656016077349
  • Chang-LinJEBurkeJAPengQPharmacokinetics of a sustained-release dexamethasone intravitreal implant in vitrectomized and nonvitrectomized eyesInvestig Ophthalmol Vis Sci20115274605460921421864
  • PavesioCZierhutMBairiKComstockTLUsnerDWFluocinolone Acetonide Study GroupEvaluation of an intravitreal fluocinolone acetonide implant versus standard systemic therapy in noninfectious posterior uveitisOphthalmology2010117356757520079922
  • CallananDGJaffeGJMartinDFPearsonPAComstockTLTreatment of posterior uveitis with a fluocinolone acetonide implant: three-year clinical trial resultsArch Ophthalmol200812691191120118779477
  • JaffeGJMartinDCallananDFluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical studyOphthalmology20061136102016690128
  • Tomkins-NetzerOLightmanSDryeLMulticenter Uveitis Steroid Treatment Trial Research GroupOutcome of treatment of uveitic macular edema: The Multicenter Uveitis Steroid Treatment Trial 2-year resultsOphthalmology2015122112351235926359188
  • FonollosaALlorençVArtarazJSafety and efficacy of intravitreal dexamethasone implants in the management of macular edema secondary to infectious uveitisRetina20163691778178527183031
  • AgarwalAHandaSAggarwalKThe role of dexamethasone implant in the management of tubercular uveitisOcul Immunol Inflamm201826688489229190170
  • JabsDARosenbaumJTFosterCSGuidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panelAm J Ophthalmol2000130449251311024423
  • PetrushkinHRogersDPavesioCThe use of topical non-steroidal anti-inflammatory drugs for uveitic cystoid macular edemaOcul Immunol Inflamm201826579579728080174
  • RadwanAEArcinueCAYangPArtornsombudhPAbu Al-FadlEMFosterCSBromfenac alone or with single intravitreal injection of bevacizumab or triamcinolone acetonide for treatment of uveitic macular edemaGraefes Arch Clin Exp Ophthalmol201325171801180623519884
  • AllegriPMurialdoUPeriSRandomized, double-blind, placebo-controlled clinical trial on the efficacy of 0.5% indomethacin eye drops in uveitic macular edemaInvest Ophthalmol Vis Sci2014553146310
  • SoheilianMEskandariARamezaniARabbanikhahZSoheilianRA pilot study of intravitreal diclofenac versus intravitreal triamcinolone for uveitic cystoid macular edemaOcul Immunol Inflamm201321212412923697857
  • KianersiFRezaeian-RamshehAPouraziziMKianersiHIntravitreal diclofenac for treatment of refractory uveitis-associated cystoid macular oedema: a before and after clinical studyActa Ophthalmol2018963e355e36029369543
  • EsmaeilpourNFRabbanikhahZSoheilianRSoheilianMIntravitreal diclofenac for refractory uveitic cystoid macular edemaJ Ophthalmic Vis Res201381475223825712
  • CoxSNHayEBirdACTreatment of chronic macular edema with acetazolamideArch Ophthalmol19881069119011953415543
  • PeppleKLNguyenMHPakzad-VaeziKResponse of inflammatory cystoid macular edema to treatment using oral acetazolamideRetina (Philadelphia, Pa) Epub2018116
  • SchillingHHeiligenhausALaubeTBornfeldNJurkliesBLong-term effect of acetazolamide treatment of patients with uveitic chronic cystoid macular edema is limited by persisting inflammationRetina200525218218815689809
  • FarberMDLamSTesslerHHJenningsTJCrossARusinMMReduction of macular oedema by acetazolamide in patients with chronic iridocyclitis: a randomised prospective crossover studyBr J Ophthalmol1994781478110697
  • WhitcupSMCsakyKGPodgorMJA randomized, masked, crossover trial of acetazolamide for cystoid macular edema in patients with uveitisOphthalmology19961037105410638684794
  • BaconPASalmonMModes of action of second-line agentsScand J Rheumatol198716Suppl 6417243589587
  • PatoEMuñoz-FernándezSFranciscoFSystematic review on the effectiveness of immunosuppressants and biological therapies in the treatment of autoimmune posterior uveitisSemin Arthritis Rheum201140431432320656330
  • MéridaSPalaciosENaveaABosch-MorellFNew immunosuppressive therapies in uveitis treatmentInt J Mol Sci2015168187781879526270662
  • PachecoPATaylorSRCuchacovichMTDiazGVAzathioprine in the management of autoimmune uveitisOcul Immunol Inflamm200816416116518716951
  • ThorneJEJabsDAPetersGBHairDDunnJPKempenJHBird-shot retinochoroidopathy: ocular complications and visual impairmentAm J Ophthalmol20051401455116038650
  • GangaputraSNewcombCWLiesegangTLMethotrexate for ocular inflammatory diseasesOphthalmology2009116112188219819748676
  • TaylorSRHabot-WilnerZPachecoPLightmanSLIntraocular methotrexate in the treatment of uveitis and uveitic cystoid macular edemaOphthalmology2009116479780119344827
  • TaylorSRJBankerASchlaenAIntraocular methotrexate can induce extended remission in some patients in noninfectious uveitisRetina201333102149215423615343
  • ThorneJEJabsDAQaziFANguyenQDKempenJHDunnJPMycophenolate mofetil therapy for inflammatory eye diseaseOphthalmology200511281472147716061096
  • GoldbergNRLyuTMoshierEGodboldJJabsDASuccess with single-agent immunosuppression for multifocal choroidopathiesAm J Ophthalmol201415861310131725194229
  • DoychevaDJägleHZierhutMMycophenolic acid in the treatment of birdshot chorioretinopathy: long-term follow-upBr J Ophthalmol2015991879125061107
  • NeriPMariottiCCiminoLMercantiLGiovanniniALong-term control of cystoid macular oedema in noninfectious uveitis with myco-phenolate mofetilInt Ophthalmol200829312713318297240
  • DoychevaDZierhutMBlumenstockGStuebigerNDeuterCMycophenolate mofetil in the therapy of uveitic macular edema – long-term resultsOcul Immunol Inflamm201220320321122489750
  • MathewsDMathewsJJonesNPLow-dose cyclosporine treatment for sight-threatening uveitis: efficacy, toxicity, and toleranceIndian J Ophthalmol20105815520029146
  • KaçmazROKempenJHNewcombCCyclosporine for ocular inflammatory diseasesOphthalmology2010117357658420031223
  • NussenblattRBPalestineAGChanCCCyclosporin a therapy in the treatment of intraocular inflammatory disease resistant to systemic corticosteroids and cytotoxic agentsAm J Ophthalmol19839632752826614105
  • NussenblattRBPalestineAGChanCCStevensGMellowSDGreenSBRandomized, double-masked study of cyclosporine compared to prednisolone in the treatment of endogenous uveitisAm J Ophthalmol199111221381461867297
  • JeonSLeeWKJungYChanges in the intraocular cytokine levels after intravitreal bevacizumab in uveitic macular edemaOcul Immunol Inflamm201220536036423030355
  • MurphyCCGreinerKPlskovaJCyclosporine vs tacrolimus therapy for posterior and intermediate uveitisArch Ophthalmol2005123563464115883282
  • HoganACMcAvoyCEDickADLeeRWLong-term efficacy and tolerance of tacrolimus for the treatment of uveitisOphthalmology200711451000100617467532
  • AgarwalARajagopalanNHassanMSirolimus for retinal and uveitic diseasesDev Ophthalmol20165527628126501229
  • ShanmuganathanVACaselyEMRajDThe efficacy of sirolimus in the treatment of patients with refractory uveitisBr J Ophthalmol200589666666915923497
  • PhillipsBNWroblewskiKJA retrospective review of oral low-dose sirolimus (rapamycin) for the treatment of active uveitisJ Ophthalmic Inflamm Infect201011293421475659
  • NguyenQDIbrahimMAWattersAOcular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE StudyJ Ophthalmic Inflamm Infect2013313223514595
  • NguyenQDSadiqMASolimanMKAgarwalAdoDVSepahYJThe effect of different dosing schedules of intravitreal sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, in the treatment of non-infectious uveitis (an American Ophthalmological Society thesis)Trans Am Ophthalmol Soc2016114
  • BuhaescuIIzzedineHCovicASirolimus – challenging current perspectivesTher Drug Monit200628557758417038868
  • GilliesMCSuTInterferon-alpha 2B enhances barrier function of bovine retinal microvascular endothelium in vitroMicrovasc Res19954932772887643749
  • TheofilopoulosANBaccalaRBeutlerBKonoDHType I interferons (alpha/beta) in immunity and autoimmunityAnnu Rev Immunol20052330733615771573
  • KötterIEcksteinAKStübigerNZierhutMTreatment of ocular symptoms of Behçet’s disease with interferon alpha 2A: a pilot studyBr J Ophthalmol19988254884949713053
  • FeronEJRothovaAvan HagenPMBaarsmaGSSuttorp-SchultenMSInterferon-alpha 2b for refractory ocular Behçet’s diseaseLancet199434389101428
  • KötterIZierhutMEcksteinAKHuman recombinant interferon alfa-2a for the treatment of Behçet’s disease with sight threatening posterior or panuveitisBr J Ophthalmol200387442343112642304
  • DeuterCMEKoetterINAGuenaydinIStuebigerNZierhutMInterferon alfa-2a: a new treatment option for long lasting refractory cystoid macular edema in uveitis? A pilot studyRetina200626778679116963852
  • BodaghiBGendronGWechslerBEfficacy of interferon alpha in the treatment of refractory and sight threatening uveitis: a retrospective monocentric study of 45 patientsBr J Ophthalmol20079133533917050581
  • DeuterCMKötterIGünaydinIStübigerNDoychevaDGZierhutMEfficacy and tolerability of interferon alpha treatment in patients with chronic cystoid macular oedema due to non-infectious uveitisBr J Ophthalmol200993790691319321469
  • FardeauCSimonARoddeBInterferon-alpha2a and systemic corticosteroid in monotherapy in chronic uveitis: results of the randomized controlled BIRDFERON studyAm J Ophthalmol201717718219428315319
  • DiwoEGueudryJSaadounDWeschlerBLehoangPBodaghiBLong-term efficacy of interferon in severe uveitis associated with Behçet diseaseOcul Immunol Inflamm2017251768427541620
  • PlskovaJGreinerKForresterJVInterferon-alpha as an effective treatment for noninfectious posterior uveitis and panuveitisAm J Ophthalmol20071441556117601428
  • ButlerNJSuhlerEBRosenbaumJTInterferon alpha 2b in the treatment of uveitic cystoid macular edemaOcul Immunol Inflamm2012202869022409560
  • MackensenFJakobESpringerCInterferon versus methotrexate in intermediate uveitis with macular edema: results of a randomized controlled clinical trialAm J Ophthalmol2013156347848623786783
  • MackensenFMaxRBeckerMDInterferons and their potential in the treatment of ocular inflammationClin Ophthalmol2009355919898628
  • DickADForresterJVLiversidgeJCopeAPThe role of tumour necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU)Prog Retin Eye Res200423661763715388077
  • Díaz-LlopisMSalomDGarcia-de-VicuñaCTreatment of refractory uveitis with adalimumab: a prospective multicenter study of 131 patientsOphthalmology201211981575158122525047
  • DobnerBCMaxRBeckerMDA three-centre experience with adalimumab for the treatment of non-infectious uveitisBr J Ophthalmol201297213413823212204
  • Al RashidiSAl FawazAKangaveDAbu El-AsrarAMLong-term clinical outcomes in patients with refractory uveitis associated with Behçet disease treated with infliximabOcul Immunol Inflamm201321646847423734940
  • Schaap-FoglerMAmerRFrilingRPrielEKramerMAnti-TNF-α agents for refractory cystoid macular edema associated with noninfectious uveitisGraefes Arch Clin Exp Ophthalmol2014252463364024366669
  • MarkomichelakisNNTheodossiadisPGPanteliaEPapaefthimiouSTheodossiadisGPSfikakisPPInfliximab for chronic cystoid macular edema associated with uveitisAm J Ophthalmol2004138464865015488796
  • MalekiASahawnehHFMaLMeeseHHeYFosterCSInfliximab therapy in patients with noninfectious intermediate uveitis resistant to conventional immunomodulatory therapyRetina201737583684327681002
  • MarkomichelakisNDelichaEMasselosSFragiadakiKKaklamanisPSfikakisPPA single infliximab infusion vs corticosteroids for acute panuveitis attacks in Behcet’s disease: a comparative 4-week studyRheumatology201150359359721097877
  • FarvardinMAfaridMShahrzadSLong-term effects of intravitreal infliximab for treatment of sight-threatening chronic noninfectious uveitisJ Ocul Pharmacol Ther201228662863122794354
  • AndroudiSTsironiEKalogeropoulosCTheodoridouABrazitikosPIntravitreal adalimumab for refractory uveitis-related macular edemaOphthalmology201011781612161620378179
  • HamamRNBarikianAWAntoniosRSIntravitreal adalimumab in active noninfectious uveitis: a pilot studyOcul Immunol Inflamm201624331932625549063
  • ImrieFRDickADBiologics in the treatment of uveitisCurr Opin Ophthalmol200718648148618163000
  • BamforthSDLightmanSLGreenwoodJUltrastructural analysis of interleukin-1 beta-induced leukocyte recruitment to the rat retinaInvest Ophthalmol Vis Sci199738125359008627
  • Tugal-TutkunIPavesioCde CordoueABernard-PoenaruOGülAUse of gevokizumab in patients with Behçet’s disease uveitis: an international, randomized, double-masked, placebo-controlled study and open-label extension studyOcular Immunol Inflamm201826710231033
  • FabianiCVitaleAEmmiGEfficacy and safety of adalimumab in Behçet’s disease-related uveitis: a multicenter retrospective observational studyClin Rheumatol201636118318927853889
  • TanakaTKishimotoTTargeting interleukin-6: all the way to treat autoimmune and inflammatory diseasesInt J Biol Sci2012891227123623136551
  • DeuterCMEZierhutMIgney-OertelATocilizumab in uveitic macular edema refractory to previous immunomodulatory treatmentOcul Immunol Inflamm201725221522026731514
  • MesquidaMMolinsBLlorençVTwenty-four month follow-up of tocilizumab therapy for refractory uveitis-related macular edemaRetina20183871361137028520640
  • AdánAMesquidaMLlorençVTocilizumab treatment for refractory uveitis-related cystoid macular edemaGraefe’s Arch Clin Exp Ophthalmol2013251112627263223893042
  • Calvo-RíoVSantos-GómezMCalvoIAnti-interleukin-6 receptor tocilizumab for severe juvenile idiopathic arthritis-associated uveitis refractory to anti-tumor necrosis factor therapy: a multicenter study of twenty-five patientsArthritis Rheumatol201769366867527696756
  • NussenblattRBPetersonJSFosterCSInitial evaluation of subcutaneous daclizumab treatments for noninfectious uveitis: a multicenter noncomparative interventional case seriesOphthalmology2005112576477015878055
  • PapaliodisGNChuDFosterCSTreatment of ocular inflammatory disorders with daclizumabOphthalmology2003110478678912689903
  • BhatPCastañeda-CervantesRADoctorPPCsFFosterCSIntravenous daclizumab for recalcitrant ocular inflammatory diseaseGraefe’s Arch Clin Exp Ophthalmol2009247568768919198869
  • WroblewskiKSenHNYehSLong-term daclizumab therapy for the treatment of noninfectious ocular inflammatory diseaseCan J Ophthalmol201146432232821816251
  • SobrinLHuangJJChristenWKafkalaCChoopongPFosterCSDaclizumab for treatment of birdshot chorioretinopathyArch Ophthalmol2008126218618268208
  • BuggageRRLevy-ClarkeGSenHNA double-masked, randomized study to investigate the safety and efficacy of daclizumab to treat the ocular complications related to Behçet’s diseaseOcul Immunol Inflamm2007152637017558830
  • ComynOLightmanSLHykinPGCorticosteroid intravitreal implants vs. ranibizumab for the treatment of vitreoretinal diseaseCurr Opin Ophthalmol201324324825423518614
  • BaeJHLeeCSLeeSCEfficacy and safety of intravitreal bevacizumab compared with intravitreal and posterior sub-tenon triamcinolone acetonide for treatment of uveitic cystoid macular edemaRetina201131111111820856170
  • Cervantes-CastañedaRAGiuliariGPGallagherMJIntravitreal bevacizumab in refractory uveitic macular edema: one-year follow-upEur J Ophthalmol200919462262919551679
  • WeissKSteinbruggerIWegerMIntravitreal VEGF levels in uveitis patients and treatment of uveitic macular oedema with intravitreal bevacizumabEye20092391812181819169227
  • KozakIShoughySSStoneDUIntravitreal antiangiogenic therapy of uveitic macular edema: a reviewJ Ocul Pharmacol Ther201733423523928165851
  • PerosaFFavoinoECaragnanoMAPreteMDammaccoFCD20: a target antigen for immunotherapy of autoimmune diseasesAutoimmun Rev20054852653116214090
  • DavatchiFShamsHRezaipoorMRituximab in intractable ocular lesions of Behcet’s disease; randomized single-blind control study (pilot study)Int J Rheum Dis201013324625220704622
  • TappeinerCHeinzCSpeckerCHeiligenhausARituximab as a treatment option for refractory endogenous anterior uveitisOphthalmic Res200739318418617534119
  • BussoneGKaswinGde MenthonMDelairEBrézinAPGuillevinLMacular oedema following rituximab infusion in two patients with Wegener’s granulomatosisClin Exp Rheumatol2010281 Suppl 57909220412711
  • GilcaMMerrillPTCystoid macular edema secondary to rituximabRetin Cases Brief Rep Epub201736
  • SalliotCDougadosMGossecLRisk of serious infections during rituximab, abatacept and anakinra treatments for rheumatoid arthritis: meta-analyses of randomised placebo-controlled trialsAnn Rheum Dis2009681253218203761
  • MiserocchiEModoratiGRituximab for noninfectious uveitisDev Ophthalmol2012519810922517208
  • FaiaLJNida SenHLiZTreatment of inflammatory macular edema with humanized anti-CD11a antibody therapyInvestig Ophthalmol Vis Sci20115296919692421498606
  • GolanSLoewensteinASurgical treatment for macular edemaSemin Ophthalmol201429424225624409947
  • GutfleischMSpitalGMingelsAPauleikhoffDLommatzschAHeiligenhausAPars plana vitrectomy with intravitreal triamcinolone: effect on uveitic cystoid macular oedema and treatment limitationsBr J Ophthalmol200791334534817005547
  • TranosPScottRZambarakjiHThe effect of pars plana vitrectomy on cystoid macular oedema associated with chronic uveitis: a randomised, controlled pilot studyBr J Ophthalmol20069091107111016723360
  • HenryCRBeckerMDYangYDavisJLPars plana vitrectomy for the treatment of uveitisAm J Ophthalmol201819014214929601822
  • RadetzkySWalterPFauserSKoizumiKKirchhofBVisual outcome of patients with macular edema after pars plana vitrectomy and indocyanine green-assisted peeling of the internal limiting membraneGraefe’s Arch Clin Exp Ophthalmol2004242427327815042375
  • MuhayaMCalderVLTowlerHMJollyGMcLauchlanMLightmanSCharacterization of phenotype and cytokine profiles of T cell lines derived from vitreous humour in ocular inflammation in manClin Exp Immunol1999116341041410361227
  • LiversidgeJDickAChengYFScottGBForresterJVRetinal antigen specific lymphocytes, TCR-gamma delta T cells and CD5+ B cells cultured from the vitreous in acute sympathetic ophthalmitisAutoimmunity19931542572667511004
  • TranosPGTsaousisKTVakalisANAsteriadesSPavesioCELong-term follow-up of inflammatory cystoid macular edemaRetina20123281624162822481481
  • BaughmanRPBarneyJBO’HareLLowerEEA retrospective pilot study examining the use of Acthar gel in sarcoidosis patientsRespir Med2016110667226626451
  • TaylorPCAbdul AzeezMKiriakidisSFilgotinib for the treatment of rheumatoid arthritisExpert Opin Investig Drugs2017261011811187
  • FeaganBGSandbornWJGasinkCUNITI–IM-UNITI Study GroupUstekinumab as induction and maintenance therapy for Crohn’s diseaseN Engl J Med2016375201946196027959607
  • López-FerrerALaizAPuigLThe safety of ustekinumab for the treatment of psoriatic arthritisExp Opin Drug Saf2017166733742
  • The Cleveland Clinic, MallinckrodtOcular Sarcoidosis Open Label Trial of ACTHAR Gel Available from: https://clinicaltrials.gov/ct2/show/NCT02725177?term=macular+edema&cond=Uveitis&rank=58. ClinicalTrials.gov Identifier: NCT02725177Accessed 15 October 2018
  • John HuangMD(ACTH) for the Treatment of Sarcoid Uveitis (ACTH) Available from: https://clinicaltrials.gov/ct2/show/NCT03473964?term=macular+edema&cond=Uveitis&rank=40. ClinicalTrials.gov Identifier: NCT03473964Accessed 15 October 2018
  • Gilead SciencesEfficacy and Safety of Filgotinib in Adults With Active Noninfectious Uveitis (Humboldt) Available from: https://clinicaltrials.gov/ct2/show/NCT03207815?term=macular+edema&cond=Uveitis&rank=45. ClinicalTrials.gov Identifier: NCT03207815Accessed 15 October 2018
  • National Eye Institute (NEI)Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis (STAR Study) Available from: https://clinicaltrials.gov/ct2/show/NCT02911116?term=ustekinumab&cond=uveitis&rank=1. ClinicalTrials.gov Identifier: NCT02911116Accessed 15 October 2018