A colon-specific prodrug of metoclopramide ameliorates colitis in an experimental rat model

Yejin YangCollege of Pharmacy, Pusan National University, Busan 609-735, South Korea, [email protected]

Wooseong KimCollege of Pharmacy, Pusan National University, Busan 609-735, South Korea, [email protected]

Dayoon KimCollege of Pharmacy, Pusan National University, Busan 609-735, South Korea, [email protected]

Seongkeun JeongCollege of Pharmacy, Pusan National University, Busan 609-735, South Korea, [email protected]

Jin-Wook YooCollege of Pharmacy, Pusan National University, Busan 609-735, South Korea, [email protected]

Yunjin JungCollege of Pharmacy, Pusan National University, Busan 609-735, South Korea, [email protected]Correspondence[email protected]

Pages 231-242 | Published online: 28 Dec 2018

Cite this article
CrossMark

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF View EPUB EPUB

References

BonazBLBernsteinCNBrain-gut interactions in inflammatory bowel diseaseGastroenterology20131441364923063970
PubMed Web of Science ®Google Scholar
Al OmranYAzizQThe brain-gut axis in health and diseaseAdv Exp Med Biol201481713515324997032
PubMed Web of Science ®Google Scholar
OhmanLSimrénMPathogenesis of IBS: role of inflammation, immunity and neuroimmune interactionsNat Rev Gastroenterol Hepatol20107316317320101257
PubMed Web of Science ®Google Scholar
RheeSHPothoulakisCMayerEAPrinciples and clinical implications of the brain-gut-enteric microbiota axisNat Rev Gastroenterol Hepatol20096530631419404271
PubMed Web of Science ®Google Scholar
CamilleriMManagement of the irritable bowel syndromeGastroenterology2001120365266811179242
PubMed Web of Science ®Google Scholar
BrzozowskiBMazur-BialyAPajdoRMechanisms by which stress affects the experimental and clinical inflammatory bowel disease (IBD): role of brain-gut axisCurr Neuropharmacol201614889290027040468
PubMed Web of Science ®Google Scholar
MittalRDebsLHPatelAPNeurotransmitters: the critical modulators regulating gut-brain axisJ Cell Physiol201723292359237227512962
PubMed Web of Science ®Google Scholar
CrowellMDWessingerSB5-HT and the brain–gut axis: opportunities for pharmacologic interventionExpert Opin Investig Drugs2007166761765
PubMed Web of Science ®Google Scholar
MayerEATillischKBradesiSReview article: modulation of the brain-gut axis as a therapeutic approach in gastrointestinal diseaseAliment Pharmacol Ther200624691993316948804
PubMed Web of Science ®Google Scholar
KoJKAuyeungKKInflammatory bowel disease: etiology, pathogenesis and current therapyCurr Pharm Des20142071082109623782147
PubMed Web of Science ®Google Scholar
ScharlMRoglerGInflammatory bowel disease pathogenesis: what is new?Curr Opin Gastroenterol201228430130922573190
PubMed Web of Science ®Google Scholar
CoatesMDTekinIVranaKEMaweGMReview article: the many potential roles of intestinal serotonin (5-hydroxytryptamine, 5-HT) signalling in inflammatory bowel diseaseAliment Pharmacol Ther201746656958028737264
PubMed Web of Science ®Google Scholar
TolstanovaGDengXAhluwaliaARole of dopamine and D2 dopamine receptor in the pathogenesis of inflammatory bowel diseaseDig Dis Sci201560102963297525972152
PubMed Web of Science ®Google Scholar
MagroFVieira-CoelhoMAFragaSImpaired synthesis or cellular storage of norepinephrine, dopamine, and 5-hydroxytryptamine in human inflammatory bowel diseaseDig Dis Sci200247121622411837726
PubMed Web of Science ®Google Scholar
LevinADvan den BrinkGRSelective inhibition of mucosal serotonin as treatment for IBD?Gut201463686686723868328
PubMed Web of Science ®Google Scholar
KawanoMTakagiRKanekoAMatsushitaSBerberine is a dopamine D1- and D2-like receptor antagonist and ameliorates experimentally induced colitis by suppressing innate and adaptive immune responsesJ Neuroimmunol2015289435526616870
PubMed Web of Science ®Google Scholar
StraubRHGrumFStrauchUAnti-inflammatory role of sympathetic nerves in chronic intestinal inflammationGut200857791192118308830
PubMed Web of Science ®Google Scholar
SpohnSNBiancoFScottRBProtective actions of epithelial 5-hydroxytryptamine 4 receptors in normal and inflamed colonGastroenterology2016151593394427480173
PubMed Web of Science ®Google Scholar
UtsumiDMatsumotoKAmagaseKHorieSKatoS5-HT3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitisBr J Pharmacol2016173111835184926990520
PubMed Web of Science ®Google Scholar
AlbibiRMccallumRWMetoclopramide: pharmacology and clinical applicationAnn Intern Med198398186956336644
PubMed Web of Science ®Google Scholar
SangerGJTranslating 5-HT receptor pharmacologyNeurogastroenterol Motil200921121235123819906028
PubMed Web of Science ®Google Scholar
PeppercornMASulfasalazine. Pharmacology, clinical use, toxicity, and related new drug developmentAnn Intern Med198410133773866147110
PubMed Web of Science ®Google Scholar
KimHKongHChoiBMetabolic and pharmacological properties of rutin, a dietary quercetin glycoside, for treatment of inflammatory bowel diseasePharm Res20052291499150916132362
PubMed Web of Science ®Google Scholar
KimWNamJLeeSJeongSJungY5-Aminosalicylic Acid Azo-Linked to Procainamide Acts as an Anticolitic Mutual Prodrug via Additive Inhibition of Nuclear Factor KappaBMol Pharm20161362126213527112518
PubMed Web of Science ®Google Scholar
YanoHHirayamaFKamadaMArimaHUekamaKColon-specific delivery of prednisolone-appended alpha-cyclodextrin conjugate: alleviation of systemic side effect after oral administrationJ Control Release2002791–310311211853922
PubMed Web of Science ®Google Scholar
JungYKimYMWhat should be considered on design of a colon-specific prodrug?Expert Opin Drug Deliv20107224525820095945
PubMed Web of Science ®Google Scholar
ParkmanHPMishraAJacobsMClinical response and side effects of metoclopramide: associations with clinical, demographic, and pharmacogenetic parametersJ Clin Gastroenterol201246649450322688145
PubMed Web of Science ®Google Scholar
LinaresVAlonsoVDomingoJLOxidative stress as a mechanism underlying sulfasalazine-induced toxicityExpert Opin Drug Saf201110225326321219240
PubMed Web of Science ®Google Scholar
GanHTChenYQOuyangQSulfasalazine inhibits activation of nuclear factor-kappaB in patients with ulcerative colitisJ Gastroenterol Hepatol20052071016102415955209
PubMed Web of Science ®Google Scholar
MorissetteGMoreauEC-GaudreaultRMarceauFN-substituted 4-aminobenzamides (procainamide analogs): an assessment of multiple cellular effects concerning ion trappingMol Pharmacol20056861576158916183854
PubMed Web of Science ®Google Scholar

Share icon
Back to Top

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

A colon-specific prodrug of metoclopramide ameliorates colitis in an experimental rat model

References

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

A colon-specific prodrug of metoclopramide ameliorates colitis in an experimental rat model

References

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date