Quercetin inhibits transforming growth factor β1-induced epithelial–mesenchymal transition in human retinal pigment epithelial cells via the Smad pathway

References

• SadakaAGiuliariGPProliferative vitreoretinopathy: current and emerging treatmentsClin Ophthalmol201261325133322942638
   PubMedGoogle Scholar
• PastorJCRojasJPastor-IdoateSDi LauroSGonzalez-BuendiaLDelgado-TiradoSProliferative vitreoretinopathy: A new concept of disease pathogenesis and practical consequencesProg Retin Eye Res20165112515526209346
   PubMed Web of Science ®Google Scholar
• ShuDYLovicuFJMyofibroblast transdifferentiation: The dark force in ocular wound healing and fibrosisProg Retin Eye Res201760446528807717
   PubMed Web of Science ®Google Scholar
• MorescalchiFDuseSGambicortiERomanoMRCostagliolaCSemeraroFProliferative vitreoretinopathy after eye injuries: an overexpression of growth factors and cytokines leading to a retinal keloidMediators Inflamm2013201326978724198445
   PubMed Web of Science ®Google Scholar
• CaiWWeiQLiuQEffect of bradykinin on TGF-β1-induced retinal pigment epithelial cell proliferation and extracellular matrix secretionBMC Ophthalmol201616119927832751
   PubMed Web of Science ®Google Scholar
• WeiQLiuQRenCEffects of bradykinin on TGF-β1-induced epithelial-mesenchymal transition in ARPE-19 cellsMol Med Rep20181745878588629436636
   PubMed Web of Science ®Google Scholar
• RenYXMaJXZhaoFAnJBGengYXLiuLYEffects of curcumin on epidermal growth factor in proliferative vitreoretinopathyCell Physiol Biochem20184752136214629975931
   PubMedGoogle Scholar
• QiuSJiangZHuangZMigration of retinal pigment epithelium cells is regulated by protein kinase Cα in vitroInvest Ophthalmol Vis Sci201354107082709024084091
   PubMed Web of Science ®Google Scholar
• González-AvilaGMéndezDLozanoDRamosCDelgadoJIturriaCRole of retinal detachment subretinal fluid on extracellular matrix metabolismOphthalmologica20042181495614688436
   PubMed Web of Science ®Google Scholar
• LinHYChenYSWangKChienHWHsiehYHYangSFFisetin inhibits epidermal growth factor-induced migration of ARPE-19 cells by suppression of AKT activation and Sp1-dependent MMP-9 expressionMol Vis20172390091029296070
   PubMed Web of Science ®Google Scholar
• SrinivasanPVijayakumarSKothandaramanSPalaniMAnti-diabetic activity of quercetin extracted from Phyllanthus emblica L. fruit: In silico and in vivo approachesJ Pharm Anal20188210911829736297
   PubMed Web of Science ®Google Scholar
• CaiHDSuSLQianDWRenal protective effect and action mechanism of Huangkui capsule and its main five flavonoidsJ Ethnopharmacol201720615215928408246
   PubMed Web of Science ®Google Scholar
• WangJQianXGaoQQuercetin increases the antioxidant capacity of the ovary in menopausal rats and in ovarian granulosa cell culture in vitroJ Ovarian Res20181115129929541
   PubMed Web of Science ®Google Scholar
• MengLQYangFYWangMSQuercetin protects against chronic prostatitis in rat model through NF-κB and MAPK signaling pathwaysProstate2018781179080029654614
   PubMed Web of Science ®Google Scholar
• Şeker KaratoprakGAydinGAltinsoyBAltinkaynakCKoşarMOcsoyIThe effect of pelargonium endlicherianum Fenzl. root extracts on formation of nanoparticles and their antimicrobial activitiesEnzyme Microb Technol201797212628010769
   PubMed Web of Science ®Google Scholar
• BalakrishnanSBhatFARaja SinghPGold nanoparticle-conjugated quercetin inhibits epithelial-mesenchymal transition, angiogenesis and invasiveness via EGFR/VEGFR-2-mediated pathway in breast cancerCell Prolif201649667869727641938
   PubMed Web of Science ®Google Scholar
• SongWZhaoXXuJZhangHQuercetin inhibits angiogenesis-mediated human retinoblastoma growth by targeting vascular endothelial growth factor receptorOncol Lett20171433343334828927086
   PubMed Web of Science ®Google Scholar
• YuDYeTXiangYQuercetin inhibits epithelial-mesenchymal transition, decreases invasiveness and metastasis, and reverses IL-6 induced epithelial-mesenchymal transition, expression of MMP by inhibiting STAT3 signaling in pancreatic cancer cellsOnco Targets Ther2017104719472929026320
   PubMed Web of Science ®Google Scholar
• PatelDHSharmaNInhibitory effect of quercetin on epithelial to mesenchymal transition in SK-MEL-28 human melanoma cells defined by in vitro analysis on 3D collagen gelsOnco Targets Ther201696445645927799792
   PubMed Web of Science ®Google Scholar
• KookDWolfAHYuALThe protective effect of quercetin against oxidative stress in the human RPE in vitroInvest Ophthalmol Vis Sci20084941712172018385095
   PubMed Web of Science ®Google Scholar
• DuLHaoMLiCQuercetin inhibited epithelial mesenchymal transition in diabetic rats, high-glucose-cultured lens, and SRA01/04 cells through transforming growth factor-β2/phosphoinositide 3-kinase/Akt pathwayMol Cell Endocrinol2017452445628501572
   PubMed Web of Science ®Google Scholar
• OhHNKimCELeeJHYangJWEffects of Quercetin in a Mouse Model of Experimental Dry EyeCornea20153491130113626203745
   PubMed Web of Science ®Google Scholar
• XuXRYuHTYangYHangLYangXWDingSHQuercetin phospholipid complex significantly protects against oxidative injury in ARPE-19 cells associated with activation of Nrf2 pathwayEur J Pharmacol20167701826643168
   PubMed Web of Science ®Google Scholar
• StoddardARKoetjeLRMitchellAKSchotanusMPUbelsJLBioavailability of antioxidants applied to stratified human corneal epithelial cellsJ Ocul Pharmacol Ther201329768168723634787
   PubMed Web of Science ®Google Scholar
• YuJLiuFCuiSJVitreous proteomic analysis of proliferative vitreoretinopathyProteomics20088173667367818752205
   PubMed Web of Science ®Google Scholar
• SuCCChanCMChenHMLutein inhibits the migration of retinal pigment epithelial cells via cytosolic and mitochondrial Akt pathways (lutein inhibits RPE cells migration)Int J Mol Sci2014158137551376725110866
   PubMed Web of Science ®Google Scholar
• KhanMABradyCJKaiserRSClinical management of proliferative vitreoretinopathy: an updateRetina201535216517525602631
   PubMed Web of Science ®Google Scholar
• EastlakeKBanerjeePJAngbohangACharterisDGKhawPTLimbGAMüller glia as an important source of cytokines and inflammatory factors present in the gliotic retina during proliferative vitreoretinopathyGlia201664449550626556395
   PubMed Web of Science ®Google Scholar
• MorescalchiFDuseSGambicortiERomanoMRCostagliolaCSemeraroFProliferative vitreoretinopathy after eye injuries: an overexpression of growth factors and cytokines leading to a retinal keloidMediators Inflamm2013201326978724198445
   PubMed Web of Science ®Google Scholar
• GarwegJGTappeinerCHalberstadtMPathophysiology of proliferative vitreoretinopathy in retinal detachmentSurv Ophthalmol201358432132923642514
   PubMed Web of Science ®Google Scholar
• CiprianDThe pathogeny of proliferative vitreoretinopathyRom J Ophthalmol2015592889226978867
   PubMedGoogle Scholar
• HoersterRFauserSCursiefenCKirchhofBHeindlLMThe influence of systemic renin-angiotensin-inhibition on ocular cytokines related to proliferative vitreoretinopathyGraefes Arch Clin Exp Ophthalmol201725591721172528600710
   PubMed Web of Science ®Google Scholar
• SunalpMWiedemannPSorgenteNRyanSJEffects of cytotoxic drugs on proliferative vitreoretinopathy in the rabbit cell injection modelCurr Eye Res1984346196236425019
   PubMed Web of Science ®Google Scholar
• JonasJBKreissigIDegenringRFTreatment of oedematous, proliferative and neovascular diseases by intravitreal triamcinolone acetonideKlin Monbl Augenheilkd20032206384390 German12830391
   PubMed Web of Science ®Google Scholar
• MoysidisSNThanosAVavvasDGMechanisms of inflammation in proliferative vitreoretinopathy: from bench to bedsideMediators Inflamm2012201281593723049173
   PubMed Web of Science ®Google Scholar
• IshikawaKHeSTerasakiHResveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathySci Rep201551638626552368
   PubMed Web of Science ®Google Scholar
• AlexAFSpitznasMTittelAPKurtsCEterNInhibitory effect of epigallocatechin gallate (EGCG), resveratrol, and curcumin on proliferation of human retinal pigment epithelial cells in vitroCurr Eye Res201035111021103320958191
   PubMed Web of Science ®Google Scholar
• ZhouXKuangXLongCCurcumin Inhibits Proliferation and Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells Via Multiple PathwaysCurr Mol Med201717431231929110611
   PubMed Web of Science ®Google Scholar
• KviecinskiMRFelipeKBCorreiaJFBrazilian Bidens pilosa Linné yields fraction containing quercetin-derived flavonoid with free radical scavenger activity and hepatoprotective effectsLibyan J Med201165651
   PubMed Web of Science ®Google Scholar
• FengJSongDJiangSQuercetin restrains TGF-β1-induced epithelial-mesenchymal transition by inhibiting Twist1 and regulating E-cadherin expressionBiochem Biophys Res Commun2018498113213829425820
   PubMed Web of Science ®Google Scholar
• FerlemiAVMakriOEMermigkiPGLamariFNGeorgakopoulosCDQuercetin glycosides and chlorogenic acid in highbush blueberry leaf decoction prevent cataractogenesis in vivo and in vitro: Investigation of the effect on calpains, antioxidant and metal chelating propertiesExp Eye Res201614525826826808488
   PubMed Web of Science ®Google Scholar
• WangZLuYShengBDingYChengXCatalpol inhibits TGF-β1-induced epithelial-mesenchymal transition in human non-small-cell lung cancer cells through the inactivation of Smad2/3 and NF-κB signaling pathwaysJ Cell Biochem Epub2018117
   Google Scholar
• ChenCLChenYHTaiMCLiangCMLuDWChenJTResveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathwayDrug Des Devel Ther201711163173
   PubMed Web of Science ®Google Scholar
• JiXWangHWuZSpecific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor β (TGF-β)/Smad3 SignalingMed Sci Monit2018241633164129555895
   PubMed Web of Science ®Google Scholar
• ZhangZHLiMHLiuDRhubarb Protect Against Tubulointerstitial Fibrosis by Inhibiting TGF-β/Smad Pathway and Improving Abnormal Metabolome in Chronic Kidney DiseaseFront Pharmacol20189102930271345
   PubMed Web of Science ®Google Scholar
• MaLZengYWeiJKnockdown of LOXL1 inhibits TGF-β1-induced proliferation and fibrogenesis of hepatic stellate cells by inhibition of Smad2/3 phosphorylationBiomed Pharmacother20181071728173530257391
   PubMed Web of Science ®Google Scholar
• ZengYZhuJShenDRepression of Smad4 by miR-205 moderates TGF-β-induced epithelial-mesenchymal transition in A549 cell linesInt J Oncol201649270070827279345
   PubMed Web of Science ®Google Scholar
• TaoSLiuMShenDZhangWWangTBaiYTGF-β/Smads Signaling Affects Radiation Response and Prolongs Survival by Regulating DNA Repair Genes in Malignant GliomaDNA Cell Biol Epub2018919
   PubMed Web of Science ®Google Scholar
• WuLZhangQMoWQuercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathwaysSci Rep201771928928839277
   PubMed Web of Science ®Google Scholar
• XinXLiXHWuJZPentamethylquercetin ameliorates fibrosis in diabetic Goto-Kakizaki rat kidneys and mesangial cells with suppression of TGF-β/Smads signalingEur J Pharmacol20137131–361523665496
   PubMed Web of Science ®Google Scholar
• LuHWuLLiuLQuercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarizationBiochem Pharmacol201815420321229753749
   PubMed Web of Science ®Google Scholar