Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway

References

• Castillo-GalvánMLMartínez-RuizFMde La Garza-CastroOElizondo-OmañaREGuzmán-LópezSStudy of peripheral nerve injury in trauma patientsGac Med Mex2014150652753225375283
   PubMed Web of Science ®Google Scholar
• LadSPNathanJKSchubertRDBoakyeMTrends in median, ulnar, radial, and brachioplexus nerve injuries in the United StatesNeurosurgery201066595396020414978
   PubMed Web of Science ®Google Scholar
• CiaramitaroPMondelliMLogulloFTraumatic peripheral nerve injuries: epidemiological findings, neuropathic pain and quality of life in 158 patientsJ Peripher Nerv Syst201015212012720626775
   PubMed Web of Science ®Google Scholar
• GrumatiPBonaldoPAutophagy in skeletal muscle homeostasis and in muscular dystrophiesCells20121332534524710479
   PubMedGoogle Scholar
• StaMCappaertNLRamekersDBaasFWadmanWJThe functional and morphological characteristics of sciatic nerve degeneration and regeneration after crush injury in ratsJ Neurosci Methods201422218919824286698
   PubMed Web of Science ®Google Scholar
• HuangHCChenLZhangHXAutophagy Promotes Peripheral Nerve Regeneration and Motor Recovery Following Sciatic Nerve Crush Injury in RatsJ Mol Neurosci201658441642326738732
   PubMed Web of Science ®Google Scholar
• SulaimanWGordonTNeurobiology of peripheral nerve injury, regeneration, and functional recovery: from bench top research to bedside applicationOchsner J201313110010823531634
   PubMedGoogle Scholar
• BargielaACerro-HerrerosEFernandez-CostaJMVilchezJJLlamusiBArteroRIncreased autophagy and apoptosis contribute to muscle atrophy in a myotonic dystrophy type 1 Drosophila modelDis Model Mech20158767969026092529
   PubMed Web of Science ®Google Scholar
• NingLXuZFuruyaNNonakaRYamadaYArikawa-HirasawaEPerlecan inhibits autophagy to maintain muscle homeostasis in mouse soleus muscleMatrix Biol201548263526319110
   PubMed Web of Science ®Google Scholar
• ZhangRXLiMXJiaZPRehmannia glutinosa: review of botany, chemistry and pharmacologyJ Ethnopharmacol2008117219921418407446
   PubMed Web of Science ®Google Scholar
• LiuYRLeiRYWangCEEffects of catalpol on ATPase and amino acids in gerbils with cerebral ischemia/reperfusion injuryNeurol Sci20143581229123324584634
   PubMed Web of Science ®Google Scholar
• CaiQYChenXSZhanXLYaoZXProtective effects of catalpol on oligodendrocyte death and myelin breakdown in a rat model of chronic cerebral hypoperfusionNeurosci Lett20114971222621524686
   PubMed Web of Science ®Google Scholar
• WangYZhangRXieJLuJYueZAnalgesic activity of catalpol in rodent models of neuropathic pain, and its spinal mechanismCell Biochem Biophys20147031565157124980862
   PubMed Web of Science ®Google Scholar
• WangCFLiDQXueHYHuBOral supplementation of catalpol ameliorates diabetic encephalopathy in ratsBrain Res2010130715816519852947
   PubMed Web of Science ®Google Scholar
• ZhuHFWanDLuoYZhouJLChenLXuXYCatalpol increases brain angiogenesis and up-regulates VEGF and EPO in the rat after permanent middle cerebral artery occlusionInt J Biol Sci20106544345320827397
   PubMed Web of Science ®Google Scholar
• AhnSMKimYRKimHNNeuroprotection and spatial memory enhancement of four herbal mixture extract in HT22 hippocampal cells and a mouse model of focal cerebral ischemiaBMC Complement Altern Med20151520226122524
   PubMed Web of Science ®Google Scholar
• ZhouHLiuJRenLRelationship between [corrected] spatial memory in diabetic rats and protein kinase Cγ, caveolin-1 in the hippocampus and neuroprotective effect of catalpolChin Med J2014127591692324571888
   PubMed Web of Science ®Google Scholar
• WanDXueLZhuHLuoYCatalpol Induces Neuroprotection and Prevents Memory Dysfunction through the Cholinergic System and BDNFEvid Based Complement Alternat Med2013201319
   Web of Science ®Google Scholar
• XiaZZhangRWuPXiaZHuYMemory defect induced by β-amyloid plus glutamate receptor agonist is alleviated by catalpol and donepezil through different mechanismsBrain Res20121441273722305339
   PubMed Web of Science ®Google Scholar
• ZhangAHaoSBiJEffects of catalpol on mitochondrial function and working memory in mice after lipopolysaccharide-induced acute systemic inflammationExp Toxicol Pathol200961546146919081713
   PubMedGoogle Scholar
• ZhangXLAnLJBaoYMWangJYJiangBd-galactose administration induces memory loss and energy metabolism disturbance in mice: protective effects of catalpolFood Chem Toxicol20084682888289418573305
   PubMed Web of Science ®Google Scholar
• Abo-GrishaNEssawySAbo-ElmattyDMAbdel-HadyZEffects of intravenous human umbilical cord blood CD34+ stem cell therapy versus levodopa in experimentally induced Parkinsonism in miceArch Med Sci2013961138115124482663
   PubMed Web of Science ®Google Scholar
• MenetVPrietoMPrivatAGiménezYRibottaMAxonal plasticity and functional recovery after spinal cord injury in mice deficient in both glial fibrillary acidic protein and vimentin genesProc Natl Acad Sci U S A2003100158999900412861073
   PubMed Web of Science ®Google Scholar
• GuJLiuHZhangNEffect of transgenic human insulin-like growth factor-1 on spinal motor neurons following peripheral nerve injuryExp Ther Med2015101192426170906
   PubMed Web of Science ®Google Scholar
• WuRYanYYaoJLiuYZhaoJLiuMCalpain 3 Expression Pattern during Gastrocnemius Muscle Atrophy and Regeneration Following Sciatic Nerve Injury in RatsInt J Mol Sci20151611269272693526569227
   PubMed Web of Science ®Google Scholar
• TanabeFYoneKKawabataNAccumulation of p62 in degenerated spinal cord under chronic mechanical compression: functional analysis of p62 and autophagy in hypoxic neuronal cellsAutophagy20117121462147122082874
   PubMed Web of Science ®Google Scholar
• GurkarAUChuKRajLIdentification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stressNat Commun20134218923877263
   PubMed Web of Science ®Google Scholar
• HeCZhuHLiHZouMHXieZDissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetesDiabetes20136241270128123223177
   PubMed Web of Science ®Google Scholar
• MaejimaYKyoiSZhaiPMst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2Nat Med201319111478148824141421
   PubMed Web of Science ®Google Scholar
• WohlgemuthSESeoAYMarzettiELeesHALeeuwenburghCSkeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exerciseExp Gerontol201045213814819903516
   PubMed Web of Science ®Google Scholar
• de PalmaCPerrottaCPellegrinoPClementiECerviaDSkeletal muscle homeostasis in duchenne muscular dystrophy: modulating autophagy as a promising therapeutic strategyFront Aging Neurosci2014618825104934
   PubMed Web of Science ®Google Scholar
• MasieroESandriMAutophagy inhibition induces atrophy and myopathy in adult skeletal musclesAutophagy20106230730920104028
   PubMed Web of Science ®Google Scholar
• GrumatiPColettoLSabatelliPAutophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degenerationNat Med201016111313132021037586
   PubMed Web of Science ®Google Scholar
• ChoiMHOwJRYangNDTanejaROxidative Stress-Mediated Skeletal Muscle Degeneration: Molecules, Mechanisms, and TherapiesOxid Med Cell Longev20162016113
   Web of Science ®Google Scholar
• SalucciSBurattiniSBaldassarriVThe peculiar apoptotic behavior of skeletal muscle cellsHistol Histopathol20132881073108723400589
   PubMed Web of Science ®Google Scholar
• BonaldoPSandriMCellular and molecular mechanisms of muscle atrophyDis Model Mech201361253923268536
   PubMed Web of Science ®Google Scholar
• ZhuHWangYLiuZAntidiabetic and antioxidant effects of catalpol extracted from Rehmannia glutinosa (Di Huang) on rat diabetes induced by streptozotocin and high-fat, high-sugar feedChin Med2016112527175212
   PubMed Web of Science ®Google Scholar
• LiDQBaoYMLiYWangCFLiuYAnLJCatalpol modulates the expressions of Bcl-2 and Bax and attenuates apoptosis in gerbils after ischemic injuryBrain Res20061115117918516928364
   PubMed Web of Science ®Google Scholar
• BaljetBDrukkerJAn acetylcholinesterase method for in toto staining of peripheral nervesStain Technol1975501313646634
   PubMed Web of Science ®Google Scholar
• BellingerDLLortonDHamillRWFeltenSYFeltenDLAcetylcho-linesterase staining and choline acetyltransferase activity in the young adult rat spleen: lack of evidence for cholinergic innervationBrain Behav Immun1993731912048219410
   PubMed Web of Science ®Google Scholar