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Original Research

Ginkgo biloba extract-761 protects myocardium by regulating Akt/Nrf2 signal pathway

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Pages 647-655 | Published online: 13 Feb 2019

References

  • HausenloyDJYellonDMMyocardial ischemia-reperfusion injury: a neglected therapeutic targetJ Clin Invest201312319210023281415
  • BellRMYellonDMThere is more to life than revascularization: therapeutic targeting of myocardial ischemia/reperfusion injuryCardiovasc Ther2011296e67e7920645988
  • JiLFuFZhangLInsulin attenuates myocardial ischemia/reperfusion injury via reducing oxidative/nitrative stressAm J Physiol Endocrinol Metab20102984E871E88020124508
  • MisraMKSarwatMBhakuniPTutejaRTutejaNOxidative stress and ischemic myocardial syndromesMed Sci Monit20091510RA209RA21919789524
  • HamdulaySSWangBBirdseyGMCelecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endotheliumFree Radic Biol Med20104881013102320083195
  • ArslanFLaiRCSmeetsMBMesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injuryStem Cell Res201310330131223399448
  • SunQShenZYDuanWNMengQTXiaZYMechanism of myocardial ischemia/reperfusion-induced acute kidney injury through DJ-1/Nrf2 pathway in diabetic ratsExp Ther Med20171454201420729104636
  • ErkensRSuvoravaTSuttonTRNrf2 deficiency unmasks the significance of nitric oxide synthase activity for cardioprotectionOxid Med Cell Longev201820183115
  • ShiCLiuJWuFYewDTGinkgo biloba extract in Alzheimer’s disease: from action mechanisms to medical practiceInt J Mol Sci201011110712320162004
  • KanterMProtective effects of Ginkgo biloba (EGb 761) on testicular torsion/detorsion-induced ischemia-reperfusion injury in ratsExp Mol Pathol201191370871321930126
  • ChengLJinZZhaoRRenKDengCYuSResveratrol attenuates inflammation and oxidative stress induced by myocardial ischemia-reperfusion injury: role of Nrf2/ARE pathwayInt J Clin Exp Med201587104201042826379832
  • YangMChenJZhaoJMengMEtanercept attenuates myocardial ischemia/reperfusion injury by decreasing inflammation and oxidative stressPLoS One201499e10802425260027
  • KawaguchiMTakahashiMHataTInflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injuryCirculation2011123659460421282498
  • GargouriBCarstensenJBhatiaHSHuellMDietzGPHFiebichBLAnti-neuroinflammatory effects of Ginkgo biloba extract EGb761 in LPS-activated primary microglial cellsPhytomedicine201844455529895492
  • LiuMYZhangLJRole of Ginkgo biloba extract in regulating 5-hydroxytrytamine and its receptor in heart failure miceZhonghua Yi Xue Za Zhi2018982520242029 Chinese29996605
  • QinYZhangYTomicIGinkgo biloba extract EGb 761 and its specific components elicit protective protein clearance through the autophagy-lysosomal pathway in Tau-Transgenic mice and cultured neuronsJ Alzheimers Dis201865124326330010136
  • MansourSMBahgatAKEl-KhatibASKhayyalMTGinkgo biloba extract (EGb 761) normalizes hypertension in 2K, 1c hypertensive rats: role of antioxidant mechanisms, ACE inhibiting activity and improvement of endothelial dysfunctionPhytomedicine2011188–964164721353510
  • ZhaoZLiuNHuangJLuPHXuXMInhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell deathJ Neurochem201111661057106521182525
  • TangYZhouGYaoLProtective effect of Ginkgo biloba leaves extract, EGb761, on myocardium injury in ischemia reperfusion rats via regulation of TLR-4/NF-κB signaling pathwayOncotarget2017849866718668029156826
  • RanKYangDLChangYTGinkgo biloba extract postconditioning reduces myocardial ischemia reperfusion injuryGenet Mol Res20141322703270824782084
  • ZhangYPengLYuXProtective effect of hydrogen sulfide on rats with myocardial ischemia/reperfusion injury and its mechanismXi Bao Yu Fen Zi Mian Yi Xue Za Zhi2015313316320 Chinese25744834
  • YinXWangXFanZHyperbaric oxygen preconditioning attenuates myocardium ischemia-reperfusion injury through upregulation of heme oxygenase 1 expressionJ Cardiovasc Pharmacol Ther201520442843825604781
  • NguyenCNKimHELeeSGCaffeoylserotonin protects human keratinocyte HaCaT cells against H2O2-induced oxidative stress and apoptosis through upregulation of HO-1 expression via activation of the PI3K/Akt/Nrf2 pathwayPhytother Res201327121810181823418094
  • HuTWeiGXiMSynergistic cardioprotective effects of Danshensu and hydroxysafflor yellow A against myocardial ischemia-reperfusion injury are mediated through the Akt/Nrf2/HO-1 pathwayInt J Mol Med2016381839427176815
  • YanDDongJSulikKKChenSYInduction of the Nrf2-driven antioxidant response by tert-butylhydroquinone prevents ethanol-induced apoptosis in cranial neural crest cellsBiochem Pharmacol201080114414920223225
  • HeMPanHChangRCSoKFBrechaNCPuMActivation of the Nrf2/HO-1 antioxidant pathway contributes to the protective effects of Lycium barbarum polysaccharides in the rodent retina after ischemia-reperfusion-induced damagePLoS One201491e8480024400114