192
Views
36
CrossRef citations to date
0
Altmetric
Original Research

Isobavachalcone isolated from Psoralea corylifolia inhibits cell proliferation and induces apoptosis via inhibiting the AKT/GSK-3β/β-catenin pathway in colorectal cancer cells

, , , , , & show all
Pages 1449-1460 | Published online: 01 May 2019

References

  • Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424. doi:10.3322/caac.2149230207593
  • Chen W, Zheng R, Baade PD. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66(2):115–132. doi:10.3322/caac.2133826808342
  • Van Cutsem E, Cervantes A, Nordlinger B, Arnold D. Metastatic colorectal cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2014;25(Suppl 3):iii1–9. doi:10.1093/annonc/mdu26025190710
  • Carlomagno C, De Stefano A, Rosanova M, et al. Multiple treatment lines and prognosis in metastatic colorectal cancer patients. Cancer Metastasis Rev. 2018. doi:10.1007/s10555-018-9748-7
  • Siegel R, Desantis C, Jemal A. Colorectal cancer statistics, 2014. CA Cancer J Clin. 2014;64(2):104–117. doi:10.3322/caac.2122024639052
  • HemaIswarya S, Doble M. Potential synergism of natural products in the treatment of cancer. Phytother Res. 2006;20(4):239–249. doi:10.1002/ptr.184116557604
  • Kuete V, Sandjo LP. Isobavachalcone: an overview. Chin J Integr Med. 2012;18(7):543–547. doi:10.1007/s11655-012-1142-722772918
  • Jing H, Zhou X, Dong X, et al. Abrogation of Akt signaling by Isobavachalcone contributes to its anti-proliferative effects towards human cancer cells. Cancer Lett. 2010;294(2):167–177. doi:10.1016/j.canlet.2010.01.03520167420
  • Jin X, Shi YI. Isobavachalcone induces the apoptosis of gastric cancer cells via inhibition of the Akt and Erk pathways. Exp Ther Med. 2016;11(2):403–408. doi:10.3892/etm.2015.290426893622
  • Shi Y. Wu WZ1, Huo A, et al. Isobavachalcone inhibits the proliferation and invasion of tongue squamous cell carcinoma cells. Oncol Lett. 2017;14(3):2852–2858. doi:10.3892/ol.2017.651728928824
  • Zhao S, Ma CM, Liu CX, et al. Autophagy inhibition enhances isobavachalcone-induced cell death in multiple myeloma cells. Int J Mol Med. 2012;30(4):939–944. doi:10.3892/ijmm.2012.106622824846
  • Nishimura R, Tabata K, Arakawa M, et al. Isobavachalcone, a chalcone constituent of angelica keiskei, induces apoptosis in neuroblastoma. Biol Pharm Bull. 2007;30(10):1878–1883.17917255
  • Wu D, Wang W, Chen W, et al. Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells. Haematologica. 2018;103(9):1472–1483. doi:10.3324/haematol.2018.18818529880605
  • Han YF, Cao GW. Linking Colorectal cancer to Wnt signaling. World J Gastroenterol. 2012;18(47):6865–6873. doi:10.3748/wjg.v18.i47.686523322982
  • Gupta A, Verma A, Mishra AK, Wadhwa G, Sharma SK, Jain CK. The Wnt pathway: emerging anticancer strategies. Recent Pat Endocr Metab Immune Drug Discov. 2013;7(2):138–147.23432158
  • Rowan AJ, Lamlum H, Ilyas M, et al. APC mutations in sporadic colorectal tumors: a mutational “hotspot” and interdependence of the “two hits”. Proc Natl Acad Sci U S A. 2000;97(7):3352–3357.10737795
  • Nagini S, Sophia J, Mishra R. Glycogen synthase kinases: moonlighting proteins with theranostic potential in cancer. Semin Cancer Biol. 2018;pii: S1044–579X(17)30179–7.
  • Van der Jeught K, Xu HC, Li YJ, et al. Drug resistance and new therapies in colorectal cancer. World J Gastroenterol. 2018;24:3834–3848. doi:10.3748/wjg.v24.i34.383430228778
  • Smith E, Palethorpe HM, Tomita Y, et al. The purified extract from the medicinal plant bacopa monnieri, bacopaside II, inhibits growth of colon cancer cells in vitro by inducing cell cycle arrest and apoptosis. Cells. 2018;7(7):pii:E81. doi:10.3390/cells7070081
  • Ahmad Hidayat AF, Chan CK, Mohamad J, Abdul Kadir H. Dioscorea bulbifera induced apoptosis through inhibition of ERK 1/2 and activation of JNK signaling pathways in HCT116 human colorectal carcinoma cells. Biomed Pharmacother. 2018;104:806–816. doi:10.1016/j.biopha.2018.05.07329860114
  • Buhrmann C, Yazdi M, Popper B, et al. Resveratrol chemosensitizes TNF-beta-induced survival of 5-FU-treated colorectal cancer cells. Nutrients. 2018;10(7):pii:E888. doi:10.3390/nu10070888
  • Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol. 2007;35(4):495–516. doi:10.1080/0192623070132033717562483
  • Prokhorova EA, Zamaraev AV, Kopeina GS, et al. Role of the nucleus in apoptosis: signaling and execution. Cell Mol Life Sci. 2015;72(23):4593–4612. doi:10.1007/s00018-015-2031-y26346492
  • Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer. 2002;2(4):277–288. doi:10.1038/nrc77612001989
  • Jänicke RU, Sprengart ML, Wati MR, et al. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J Biol Chem. 1998;273(16):9357–9360.9545256
  • Schultz DR, Harrington WJ Jr. Apoptosis: programmed cell death at a molecular level. Semin Arthritis Rheum. 2003;32(6):345–369. doi:10.1053/sarh.2003.5000512833244
  • Lessene G, Czabotar PE, Colman PM. BCL-2 family antagonists for cancer therapy. Nat Rev Drug Discov. 2008;7(12):989–1000. doi:10.1038/nrd265819043450
  • Adams JM, Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 1998;281(5381):1322–1326.9735050
  • Pandurangan AK, Divya T, Kumar K, et al. Colorectal carcinogenesis: insights into the cell death and signal transduction pathways: a review. World J Gastrointest Oncol. 2018;10(9):244–259. doi:10.4251/wjgo.v10.i9.24430254720
  • Doerks T, Copley RR, Schultz J, Ponting CP, Bork P. Systematic identification of novel protein domain families associated with nuclear functions. Genome Res. 2002;12(1):47–56.11779830
  • Liu YZ, Wu K, Huang J, et al. The PTEN/PI3K/Akt and Wnt/beta-catenin signaling pathways are involved in the inhibitory effect of resveratrol on human colon cancer cell proliferation. Int J Oncol. 2014;45(1):104–112. doi:10.3892/ijo.2014.239224756222
  • Park CH, Chang JY, Hahm ER, et al. Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells. Biochem Biophys Res Commun. 2005;328(1):227–234. doi:10.1016/j.bbrc.2004.12.15115670774
  • Dou H, Shen R, Tao J, et al. Curcumin suppresses the colon cancer proliferation by inhibiting Wnt/beta-catenin pathways via miR-130a. Front Pharmacol. 2017;8:877. doi:10.3389/fphar.2017.0087729225578
  • MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell. 2009;17(1):9–26. doi:10.1016/j.devcel.2009.06.01619619488
  • Zhuang YW, Wu CE, Zhou JY, et al. Solasodine inhibits human colorectal cancer cells through suppression of the AKT/glycogen synthase kinase-3beta/beta-catenin pathway. Cancer Sci. 2017;108(11):2248–2264. doi:10.1111/cas.1335428803443
  • Guo H, Luo H, Yuan H, et al. Litchi seed extracts diminish prostate cancer progression via induction of apoptosis and attenuation of EMT through Akt/GSK-3beta signaling. Sci Rep. 2017;7:41656. doi:10.1038/srep4165628134352
  • Saiprasad G, Chitra P, Manikandan R, et al. Hesperidin induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated phosphoinositide-3-kinase/Akt/mammalian target of rapamycin and glycogen synthase kinase-3 beta signalling cascades in experimental colon carcinogenesis. Eur J Cancer. 2014;50(14):2489–2507. doi:10.1016/j.ejca.2014.06.01325047426