178
Views
32
CrossRef citations to date
0
Altmetric
Original Research

Cathepsin G cleaves and activates IL-36γ and promotes the inflammation of psoriasis

, , , &
Pages 581-588 | Published online: 08 Feb 2019

References

  • BaliwagJBarnesDHJohnstonACytokines in psoriasisCytokine201573234235025585875
  • JohnstonAXingXWolterinkLIL-1 and IL-36 are dominant cytokines in generalized pustular psoriasisJ Allergy Clin Immunol2017140110912028043870
  • GresnigtMSvan de VeerdonkFLBiology of IL-36 cytokines and their role in diseaseSemin Immunol201325645846524355486
  • KumarSMcDonnellPCLehrRIdentification and initial characterization of four novel members of the interleukin-1 familyJ Biol Chem200027514103081031410744718
  • FosterAMBaliwagJChenCSIL-36 promotes myeloid cell infiltration, activation, and inflammatory activity in skinJ Immunol2014192126053606124829417
  • JohnstonAXingXGuzmanAMIL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expressionJ Immunol201118642613262221242515
  • LiBTsoiLCSwindellWRTranscriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanismsJ Invest Dermatol201413471828183824441097
  • D’ErmeAMWilsmann-TheisDWagenpfeilJIL-36γ (IL-1F9) is a biomarker for psoriasis skin lesionsJ Invest Dermatol201513541025103225525775
  • SullivanGPHenryCMClancyDMSuppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteasesCell Death Dis20189337829515113
  • HenryCMSullivanGPClancyDMAfoninaISKulmsDMartinSJNeutrophil-derived proteases escalate inflammation through activation of IL-36 family cytokinesCell Rep201614470872226776523
  • ZhouBRZhangJAZhangQPalmitic acid induces production of proinflammatory cytokines interleukin-6, interleukin-1β, and tumor necrosis factor-α via a NF-κB-dependent mechanism in HaCaT keratinocytesMediators Inflamm2013201353042924078775
  • ClarkRANauseefWMIsolation and functional analysis of neutrophilsCurr Protoc Immunol2001
  • YinLHuYXuJGuoJTuJYinZUltraviolet B inhibits IL-17A/ TNF-α-Stimulated activation of human dermal fibroblasts by decreasing the expression of IL-17RA and IL-17RC on fibroblastsFront Immunol201789128217129
  • BassoyEYTowneJEGabayCRegulation and function of interleukin-36 cytokinesImmunol Rev2018281116917829247994
  • CaponFThe genetic basis of psoriasisInt J Mol Sci201718122526
  • PfaffCMMarquardtYFietkauKBaronJMLüscherBThe psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and functionSci Rep2017711563129142248
  • WangWYuXWuCJinHIL-36γ inhibits differentiation and induces inflammation of keratinocyte via Wnt signaling pathway in psoriasisInt J Med Sci201714101002100728924372
  • TowneJEGarkaKERenshawBRVircaGDSimsJEInterleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKsJ Biol Chem200427914136771368814734551
  • BerekmériALatzkoAAlaseAMacleodTAinscoughJSLawsPDetection of IL-36y via non-invasive tape stripping reliably discriminates psoriasis from atopic eczemaJ Allergy Clin Immunol2018142398899129782895
  • TowneJERenshawBRDouangpanyaJInterleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activityJ Biol Chem201128649425944260221965679
  • AinscoughJSMacleodTMcGonagleDCathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γProc Natl Acad Sci U S A201711413E2748E275728289191
  • SullivanGPDavidovichPBSura-TruebaSIdentification of small-molecule elastase inhibitors as antagonists of IL-36 cytokine activationFEBS Open Bio201885751763
  • SwindellWRMichaelsKASutterAJImiquimod has strain-dependent effects in mice and does not uniquely model human psoriasisGenome Med2017912428279190
  • TortolaLRosenwaldEAbelBPsoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalkJ Clin Invest2012122113965397623064362
  • van der FitsLMouritsSVoermanJSImiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/ IL-17 axisJ Immunol200918295836584519380832
  • FlutterBNestleFOTLRs to cytokines: mechanistic insights from the imiquimod mouse model of psoriasisEur J Immunol201343123138314624254490
  • MiloraKAFuHDubazOJensenLEUnprocessed Interleukin-36α regulates psoriasis-like skin inflammation in cooperation with interleukin-1J Invest Dermatol2015135122992300026203636