164
Views
105
CrossRef citations to date
0
Altmetric
Original Research

Emodin alleviates myocardial ischemia/reperfusion injury by inhibiting gasdermin D-mediated pyroptosis in cardiomyocytes

, , , , , , , & show all
Pages 975-990 | Published online: 25 Mar 2019

References

  • ReedGWRossiJECannonCPAcute myocardial infarctionLancet20173891006519721027502078
  • IbáñezBHeuschGOvizeMVan de WerfFEvolving therapies for myocardial ischemia/reperfusion injuryJ Am Coll Cardiol201565141454147125857912
  • HausenloyDJYellonDMTime to take myocardial reperfusion injury seriouslyN Engl J Med2008359551852018669431
  • OshiroYShimabukuroMTakasuNAsahiTKomiyaIYoshidaHTri-iodothyronine concomitantly inhibits calcium overload and postischemic myocardial stunning in diabetic ratsLife Sci200169161907191811693271
  • MaczewskiMBeresewiczAThe role of endothelin, protein kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig heartsJ Mol Cell Cardiol200032229731010722805
  • YellonDMHausenloyDJMyocardial reperfusion injuryN Engl J Med2007357111121113517855673
  • KawaguchiMTakahashiMHataTInflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injuryCirculation2011123659460421282498
  • CooksonBTBrennanMAPro-inflammatory programmed cell deathTrends Microbiol20019311311411303500
  • JorgensenIMiaoEAPyroptotic cell death defends against intracellular pathogensImmunol Rev2015265113014225879289
  • FinkSLCooksonBTCaspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophagesCellular Microbiol200681118121825
  • ShiJZhaoYWangKCleavage of GSDMD by inflammatory caspases determines pyroptotic cell deathNature2015526757566066526375003
  • DingJWangKLiuWPore-forming activity and structural auto-inhibition of the gasdermin familyNature2016535761011111627281216
  • WoodallMCWoodallBPGaoEYuanAKochWJCardiac fibroblast GRK2 deletion enhances contractility and remodeling following ischemia/reperfusion injuryCirc Res2016119101116112727601479
  • OngSBHernández-ReséndizSCrespo-AvilanGEInflammation following acute myocardial infarction: multiple players, dynamic roles, and novel therapeutic opportunitiesPharmacol Ther2018186738729330085
  • OyamaJBlaisCJrLiuXReduced myocardial ischemia-reperfusion injury in Toll-like receptor 4-deficient miceCirculation2004109678478914970116
  • ShibataMEndoSInadaKElevated plasma levels of interleukin-1 receptor antagonist and interleukin-10 in patients with acute myocardial infarctionJ Interferon Cytokine Res19971731451509085939
  • SuzukiKMurtuzaBSmolenskiRTOverexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosisCirculation2001104suppl 1I-308I-31311568074
  • WuZChenQKeDLiGDengWEmodin protects against diabetic cardiomyopathy by regulating the Akt/GSK-3β signaling pathway in the rat modelMolecules2014199147821479325232702
  • LiHYangTZhouHDuJZhuBSunZEmodin combined with Nanosilver inhibited sepsis by anti-inflammatory protectionFront Pharmacol2016753628119611
  • XueJChenFWangJEmodin protects against concanavalin A-induced hepatitis in mice through inhibiting activation of the p38 MAPK-NF-kappaB signaling pathwayCell Physiol Biochem20153541557157025792514
  • DuYKoKMEffects of pharmacological preconditioning by emodin/oleanolic acid treatment and/or ischemic preconditioning on mitochondrial antioxidant components as well as the susceptibility to ischemia-reperfusion injury in rat heartsMol Cell Biochem20062881–213514216583138
  • de CoutoGGalletRCambierLExosomal microRNA transfer into macrophages mediates cellular postconditioningCirculation2017136220021428411247
  • IzumiTSaitoYKishimotoIBlockade of the natriuretic peptide receptor guanylyl cyclase-A inhibits NF-kappaB activation and alleviates myocardial ischemia/reperfusion injuryJ Clin Invest2001108220321311457873
  • BauernfeindFGHorvathGStutzACutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expressionJ Immunol2009183278779119570822
  • ManSMKannegantiTDGasdermin D: the long-awaited executioner of pyroptosisCell Research201525111183118426482951
  • VeTVajjhalaPRHedgerAStructural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signalingNat Struct Mol Biol201724974375128759049
  • DingYLiuPChenZLEmodin attenuates lipopolysaccharide-induced acute liver injury via inhibiting the TLR4 signaling pathway in vitro and in vivoFront Pharmacol2018996230186181
  • LiangWChenMZhengDThe opening of ATP-sensitive K+ channels protects H9c2 cardiac cells against the high glucose-induced injury and inflammation by inhibiting the ROS-TLR4-necroptosis pathwayCell Physiol Biochem20174131020103428291959
  • WeiMLiZXiaoLYangZEffects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injuryMol Immunol2015682 Pt A26127126364141
  • YangZDayYJToufektsianMCInfarct-sparing effect of A2A-adenosine receptor activation is due primarily to its action on lymphocytesCirculation2005111172190219715851591
  • De MeyerSFSavchenkoASHaasMSProtective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/ reperfusion injury in miceBlood2012120265217522322915644
  • AfoninaISZhongZKarinMBeyaertRLimiting inflammation-the negative regulation of NF-κB and the NLRP3 inflammasomeNat Immunol201718886186928722711
  • Munoz-PlanilloRKuffaPMartinez-ColonGSmithBLRajendiranTMNunezGK(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matterImmunity20133861142115323809161
  • CompanVBaroja-MazoALópez-CastejónGCell volume regulation modulates NLRP3 inflammasome activationImmunity201237348750022981536
  • ShimadaKCrotherTRKarlinJOxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosisImmunity201236340141422342844
  • IvesANomuraJMartinonFXanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activationNat Commun201561655525800347
  • SborgiLRühlSMulvihillEGSDMD membrane pore formation constitutes the mechanism of pyroptotic cell deathEMBO J201635161766177827418190
  • ShiJGaoWShaoFPyroptosis: Gasdermin-Mediated programmed necrotic cell deathTrends Biochem Sci201742424525427932073
  • XuBJiangMChuYGasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and miceJ Hepatol201868477378229273476
  • ChengKTXiongSYeZCaspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injuryJ Clin Invest2017127114124413528990935
  • WuXZhangHQiWNicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosisCell Death Dis20189217129416034
  • XiaoMZhuTZhangWEmodin ameliorates LPS-induced acute lung injury, involving the inactivation of NF-κB in miceInt J Mol Sci20141511193551936825347274
  • LiuZGanLXuYMelatonin alleviates inflammasome-induced pyroptosis through inhibiting NF-κB/GSDMD signal in mice adipose tissueJ Pineal Res2017631e12414
  • CumminsEPBerraEComerfordKMProlyl hydroxylase-1 negatively regulates I B kinase-beta, giving insight into hypoxia-induced NF B activityProc Natl Acad Sci U S A200610348181541815917114296
  • LorneEDupontHAbrahamEToll-like receptors 2 and 4: initiators of non-septic inflammation in critical care medicine?Intensive Care Med201036111826183520689929