118
Views
4
CrossRef citations to date
0
Altmetric
Original Research

The neuroprotective effect of bisperoxovandium (pyridin-2-squaramide) in intracerebral hemorrhage

, , , , , , , , , , , , & show all
Pages 1957-1967 | Published online: 13 Jun 2019

References

  • Qureshi AI, Mendelow AD, Hanley DF. Intracerebral haemorrhage. Lancet. 2009;373:1632–1644. doi:10.1016/S0140-6736(09)60371-819427958
  • Xiong XY, Wang J, Qian ZM, Yang QW. Iron and intracerebral hemorrhage: from mechanism to translation. Transl Stroke Res. 2014;5:429–441. doi:10.1007/s12975-013-0317-724362931
  • Chang N, El-Hayek YH, Gomez E, Wan Q. Phosphatase PTEN in neuronal injury and brain disorders. Trends Neurosci. 2007;30:581–586. doi:10.1016/j.tins.2007.08.00617959258
  • Jiang B, Li L, Chen Q, et al. Role of glibenclamide in brain injury after intracerebral hemorrhage. Transl Stroke Res. 2017;8:183–193. doi:10.1007/s12975-016-0506-227807801
  • Li Y, Wang H, Muffat J, et al. Global transcriptional and translational repression in human-embryonic-stem-cell-derived rett syndrome neurons. Cell Stem Cell. 2013;13:446–458. doi:10.1016/j.stem.2013.09.00124094325
  • Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science. 2002;298:1911–1912. doi:10.1126/science.107268212471242
  • Sanclemente M, Francoz S, Esteban-Burgos L, et al. c-RAF ablation induces regression of advanced Kras/Trp53 mutant lung adenocarcinomas by a mechanism independent of MAPK Signaling. Cancer Cell. 2018;33:217–228.e214. doi:10.1016/j.ccell.2017.12.01429395869
  • Han J, Feng Z, Xie Y, et al. Oncostatin M-induced upregulation of SDF-1 improves bone marrow stromal cell migration in a rat middle cerebral artery occlusion stroke model. Exp Neurol. 2019;313:49–59. doi:10.1016/j.expneurol.2018.09.00530213507
  • Baumgartner C, Toifl S, Farlik M, et al. An ERK-dependent feedback mechanism prevents hematopoietic stem cell exhaustion. Cell Stem Cell. 2018;22:879–892.e876. doi:10.1016/j.stem.2018.05.00329804890
  • Gwinn DM, Lee AG, Briones-Martin-Del-Campo M, et al. Oncogenic KRAS regulates amino acid homeostasis and asparagine biosynthesis via ATF4 and alters sensitivity to L-Asparaginase. Cancer Cell. 2018;33:91–107.e106. doi:10.1016/j.ccell.2017.12.00329316436
  • Huyer G, Liu S, Kelly J, et al. Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate. J Biol Chem. 1997;272:843–851.8995372
  • Rosivatz E, Matthews JG, McDonald NQ, et al. A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN). ACS Chem Biol. 2006;1:780–790. doi:10.1021/cb600352f17240976
  • Schmid AC, Byrne RD, Vilar R, Woscholski R. Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Lett. 2004;566:35–38. doi:10.1016/j.febslet.2004.03.10215147864
  • Sury MD, Vorlet-Fawer L, Agarinis C, et al. Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis. Neurobiol Dis. 2011;41:201–208. doi:10.1016/j.nbd.2010.09.00720875857
  • Tan L, Chen X, Wang W, et al. Pharmacological inhibition of PTEN attenuates cognitive deficits caused by neonatal repeated exposures to isoflurane via inhibition of NR2B-mediated tau phosphorylation in rats. Neuropharmacology. 2017;114:135–145. doi:10.1016/j.neuropharm.2016.11.00827836791
  • Marin C, Ximenis M, Ramirez-Macias I, et al. Effective anti-leishmanial activity of minimalist squaramide-based compounds. Exp Parasitol. 2016;170:36–49. doi:10.1016/j.exppara.2016.07.01327480054
  • Olmo F, Rotger C, Ramirez-Macias I, et al. Synthesis and biological evaluation of N,N‘-squaramides with high in vivo efficacy and low toxicity: toward a low-cost drug against chagas disease. J Med Chem. 2014;57:987–999. doi:10.1021/jm401701524410674
  • Chan PC, Roon RJ, Koerner JF, Taylor NJ, Honek JF. A 3-amino-4-hydroxy-3-cyclobutene-1,2-dione-containing glutamate analogue exhibiting high affinity to excitatory amino acid receptors. J Med Chem. 1995;38:4433–4438.7473569
  • Hill ND, Bunata K, Hebert AA. Treatment of alopecia areata with squaric acid dibutylester. Clin Dermatol. 2015;33:300–304. doi:10.1016/j.clindermatol.2014.12.00125889130
  • Zhang ZF, Chen J, Han X, et al. Bisperoxovandium (pyridin-2-squaramide) targets both PTEN and ERK1/2 to confer neuroprotection. Br J Pharmacol. 2017;174:641–656. doi:10.1111/bph.1372728127755
  • Mehdi MZ, Pandey SK, Theberge JF, Srivastava AK. Insulin signal mimicry as a mechanism for the insulin-like effects of vanadium. Cell Biochem Biophys. 2006;44:73–81. doi:10.1385/Cbb:44:1:07316456236
  • Mao LL, Hao DL, Mao XW, et al. Neuroprotective effects of bisperoxovanadium on cerebral ischemia by inflammation inhibition. Neurosci Lett. 2015;602:120–125. doi:10.1016/j.neulet.2015.06.04026141612
  • Liu R, Tang JC, Pan MX, et al. ERK 1/2 activation mediates the neuroprotective effect of bpV(pic) in focal cerebral ischemia-reperfusion injury. Neurochem Res. 2018;43:1424–1438. doi:10.1007/s11064-018-2558-z29882124
  • Zhang QG, Wu DN, Han D, Zhang GY. Critical role of PTEN in the coupling between PI3K/Akt and JNK1/2 signaling in ischemic brain injury. FEBS Lett. 2007;581:495–505. doi:10.1016/j.febslet.2006.12.05517239858
  • Chen Y, Zhang Y, Tang J, et al. Norrin protected blood-brain barrier via frizzled-4/beta-catenin pathway after subarachnoid hemorrhage in rats. Stroke. 2015;46:529–536. doi:10.1161/STROKEAHA.114.00726525550365
  • Moisan A, Favre I, Rome C, et al. Intravenous injection of clinical grade human MSCs after experimental stroke: functional benefit and microvascular effect. Cell Transplant. 2016;25:2157–2171. doi:10.3727/096368916X69113226924704
  • Sharma S, Taliyan R. High fat diet feeding induced insulin resistance exacerbates 6-OHDA mediated neurotoxicity and behavioral abnormalities in rats. Behav Brain Res. 2018;351:17–23. doi:10.1016/j.bbr.2018.05.02529842916
  • Yang C, DeMars KM, Alexander JC, Febo M, Candelario-Jalil E. Sustained neurological recovery after stroke in aged rats treated with a novel prostacyclin analog. Stroke. 2017;48:1948–1956. doi:10.1161/STROKEAHA.117.01647428588054
  • Dhar D, Antonucci L, Nakagawa H, et al. Liver cancer initiation requires p53 inhibition by CD44-enhanced growth factor signaling. Cancer Cell. 2018;33:1061–1077.e1066. doi:10.1016/j.ccell.2018.05.00329894692
  • Ning K, Pei L, Liao M, et al. Dual neuroprotective signaling mediated by downregulating two distinct phosphatase activities of PTEN. J Neurosci. 2004;24:4052–4060. doi:10.1523/JNEUROSCI.5449-03.200415102920
  • Gigliozzi A, Alpini G, Baroni GS, et al. Nerve growth factor modulates the proliferative capacity of the intrahepatic biliary epithelium in experimental cholestasis. Gastroenterology. 2004;127:1198–1209.15480997
  • Zheng M, Liao M, Cui T, et al. Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN. J Cell Sci. 2012;125:1556–1567. doi:10.1242/jcs.09572922526419
  • Liu B, Li L, Zhang Q, et al. Preservation of GABAA receptor function by PTEN inhibition protects against neuronal death in ischemic stroke. Stroke. 2010;41:1018–1026. doi:10.1161/STROKEAHA.110.57901120360540
  • Roskoski R Jr. ERK1/2 MAP kinases: structure, function, and regulation. Pharmacol Res. 2012;66:105–143. doi:10.1016/j.phrs.2012.04.00522569528
  • Kwon KJ, Kim JN, Kim MK, et al. Neuroprotective effects of valproic acid against hemin toxicity: possible involvement of the down-regulation of heme oxygenase-1 by regulating ubiquitin-proteasomal pathway. Neurochem Int. 2013;62:240–250. doi:10.1016/j.neuint.2012.12.01923298644
  • Lou N, Takano T, Pei Y, et al. Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier. Proc Natl Acad Sci U S A. 2016;113:1074–1079. doi:10.1073/pnas.152039811326755608
  • Gajera CR, Emich H, Lioubinski O, et al. LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche. J Cell Sci. 2010;123:1922–1930. doi:10.1242/jcs.06591220460439
  • Ihrie RA, Shah JK, Harwell CC, et al. Persistent sonic hedgehog signaling in adult brain determines neural stem cell positional identity. Neuron. 2011;71:250–262. doi:10.1016/j.neuron.2011.05.01821791285
  • Imayoshi I, Kageyama R. The role of Notch signaling in adult neurogenesis. Mol Neurobiol. 2011;44:7–12. doi:10.1007/s12035-011-8186-021541768
  • Gajera CR, Fernandez R, Postupna N, et al. Mass synaptometry: high-dimensional multi parametric assay for single synapses. J Neurosci Methods. 2019;312:73–83. doi:10.1016/j.jneumeth.2018.11.00830465796