Advanced search
Publication Cover
Drug Design, Development and Therapy Volume 13, 2019 - Issue
Submit an article Journal homepage
160
Views
25
CrossRef citations to date
0
Altmetric
Original Research

Jatrorrhizine inhibits colorectal carcinoma proliferation and metastasis through Wnt/β-catenin signaling pathway and epithelial–mesenchymal transition

Pan Wang1 College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, People’s Republic of China
,
Xiao-Yan Gao1 College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, People’s Republic of China
,
Si-Qian Yang1 College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, People’s Republic of China
,
Zhi-Xin Sun2 College of Life Sciences, Wenzhou Medical University, Wenzhou325035, People’s Republic of China;3 Department of Life Sciences, Zaozhuang No.1 Middle School, Zaozhuang, 277100, People’s Republic of China
,
Lu-Lu Dian1 College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, People’s Republic of China
,
Muhammad Qasim1 College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, People’s Republic of China;4 Institute of Sustainable Halophyte Utilization, University of Karachi, Karachi75270, Pakistan
,
Aung Thu Phyo1 College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, People’s Republic of China;5 Department of Biotechnology, Mandalay Technological University, Mandalay05072, Myanmar
,
Zong-Suo Liang1 College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, People’s Republic of ChinaCorrespondence[email protected] [email protected]
&
Yan-Fang Sun1 College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou310018, People’s Republic of ChinaCorrespondence[email protected] [email protected]
 show all
Pages 2235-2247 | Published online: 08 Jul 2019

References

  • Piyanuch R, Sukhthankar M, Wandee G, Baek SJ. Berberine, a natural isoquinoline alkaloid, induces NAG-1 and ATF3 expression in human colorectal cancer cells. Cancer Lett. 2007;258(2):230–240. doi:10.1016/j.canlet.2007.09.00717964072
  • Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA Cancer J Clin. 2019;69(1):7–34. doi:10.3322/caac.2155130620402
  • Han B, Jiang P, Li Z, et al. Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway. Phytomedicine. 2018;48:152–160. doi:10.1016/j.phymed.2017.12.02730195873
  • Ambrož M, Šmatová M, Šadibolov M, et al. Sesquiterpenes α-humulene and β-caryophyllene oxide enhance the efficacy of 5-fluorouracil and oxaliplatin in colon cancer cells. Acta Pharm. 2019;69:121–128. doi:10.2478/acph-2019-000331259712
  • Peng L, Yuan XQ, Zhang CY, et al. The emergence of long non-coding RNAs in hepatocellular carcinoma: an update. J Cancer. 2018;9(14):2549–2558. doi:10.7150/jca.2456030026854
  • Lee JH, Cho HS, Lee JJ, et al. Plasma glutamate carboxypeptidase is a negative regulator in liver cancer metastasis. Oncotarget. 2016;7(48):79774–79786. doi:10.18632/oncotarget.1296727806330
  • Zhang J, Tian XJ, Xing J. Signal transduction pathways of EMT induced by TGF-beta, SHH, and WNT and their crosstalks. J Clin Med. 2016;5(4). doi:10.3390/jcm5040041
  • Guo YH, Wang LQ, Li B, et al. Wnt/β-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling. Oncotarget. 2016;7(27):42513–42526. doi:10.18632/oncotarget.989327285761
  • Chai FN, Ma WY, Zhang J, et al. Coptisine from Rhizoma coptidis exerts an anti-cancer effect on hepatocellular carcinoma by up-regulating miR-122. Biomed Pharmacother. 2018;103:1002–1011. doi:10.1016/j.biopha.2018.04.05229710498
  • Choi SU, Baek NI, Kim SH, et al. Cytotoxic isoquinoline alkaloids from the aerial parts of corydalis incisa. Arch Pharm Res. 2007;30(2):151–154.17366734
  • Ito C, Itoigawa M, Itoigawa M, Kuchide M, Nishino H, Furukawa H. Chemopreventive activity of isoquinoline alkaloids from corydalis plants. Planta Med. 2001;67(5):473–475. doi:10.1055/s-2001-1581511488467
  • Zhu SL, Lei T, Gao X, Tu J. Jatrorrhizine regulates GLUTs with multiple manners for hypoglycemic effect in insulin-resistance 3T3-L1 adipocytes. Zhongguo Zhong Yao Za Zhi. 2018;43(6):1215–1220. doi:10.19540/j.cnki.cjcmm.20180104.00529676131
  • Wu H, He K, Wang Y, et al. The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma coptidis. Phytomedicine. 2014;21(11):1373–1381. doi:10.1016/j.phymed.2014.05.00224894270
  • Liu X, Ji Q, Ye N, et al. Berberine inhibits invasion and metastasis of colorectal cancer cells via COX-2/PGE2 mediated JAK2/STAT3 signaling pathway. PLoS One. 2015;10(5):e0123478. doi:10.1371/journal.pone.012347825954974
  • Sun Y, Wu P, Sun Y, et al. Lycorine possesses notable anticancer potentials in on-small cell lung carcinoma cells via blocking Wnt/beta-catenin signaling and epithelial-mesenchymal transition (EMT). Biochem Biophys Res Commun. 2018;495(1):911–921. doi:10.1016/j.bbrc.2017.11.03229127013
  • Luo T, Zhang H, Zhang WW, et al. Neuroprotective effect of Jatrorrhizine on hydrogen peroxide-induced cell injury and its potential mechanisms in PC12 cells. Neurosci Lett. 2011;498(3):227–231. doi:10.1016/j.neulet.2011.05.01721605627
  • Tai D, Wells K, Arcaroli J, et al. Targeting the WNT signaling pathway in cancer therapeutics. Oncologist. 2015;20(10):1189–1198. doi:10.1634/theoncologist.2015-005726306903
  • Clevers H, Nusse R. Wnt/beta-catenin signaling and disease. Cell. 2012;149(6):1192–1205. doi:10.1016/j.cell.2012.05.01222682243
  • Tian D, Shi Y, Chen D, Liu Q, Fan F. The Wnt inhibitor LGK-974 enhances radiosensitivity of HepG2 cells by modulating Nrf2 signaling. Int J Oncol. 2017;51(2):545–554. doi:10.3892/ijo.2017.404228627706
  • Yang S, Liu Y, Li MY, et al. FOXP3 promotes tumor growth and metastasis by activating Wnt/beta-catenin signaling pathway and EMT in non-small cell lung cancer. Mol Cancer. 2017;16:124–136. doi:10.1186/s12943-017-0700-128716029

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.