Pregnancy And Neonatal Outcomes Of hMG Stimulation With Or Without Letrozole In Endometrial Preparation For Frozen–Thawed Embryo Transfer In Ovulatory Women: A Large Retrospective Cohort Study

References

• De Neubourg D, Peeraer K, Debrock S, D’Hooghe T. Belgium model of coupling reimbursement of ART costs to restriction in number of embryos transferred. BMJ. 2014;348:g1559. doi:10.1136/bmj.g155924554176
   PubMed Web of Science ®Google Scholar
• Roque M, Lattes K, Serra S, et al. Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles: a systematic review and meta-analysis. Fertil Steril. 2013;99:156–162. doi:10.1016/j.fertnstert.2012.09.00323040524
   PubMed Web of Science ®Google Scholar
• Sirmans SM, Pate KA. Epidemiology, diagnosis, and management of polycystic ovary syndrome. Clin Epidemiol. 2013;6:1–13. doi:10.2147/CLEP.S3755924379699
   PubMed Web of Science ®Google Scholar
• Jensen TK, Scheike T, Keiding N, Schaumburg I, Grandjean P. Fecundability in relation to body mass and menstrual cycle patterns. Epidemiology. 1999;422–428. doi:10.1097/00001648-199907000-0001410401878
   PubMed Web of Science ®Google Scholar
• Rowland AS, Baird DD, Long S, et al. Influence of medical conditions and lifestyle factors on the menstrual cycle. Epidemiology. 2002;13:668–674. doi:10.1097/00001648-200211000-0001112410008
   PubMed Web of Science ®Google Scholar
• Lyngsø J, Toft G, Høyer BB, Guldbrandsen K, Olsen J, Ramlau-Hansen C. Moderate alcohol intake and menstrual cycle characteristics. Hum Reprod. 2014;29:351–358. doi:10.1093/humrep/det41724287817
   PubMed Web of Science ®Google Scholar
• Achache H, Revel A. Endometrial receptivity markers, the journey to successful embryo implantation. Hum Reprod Update. 2006;12:731–746. doi:10.1093/humupd/dml00416982667
   PubMed Web of Science ®Google Scholar
• Peeraer K, Couck I, Debrock S, et al. Frozen–thawed embryo transfer in a natural or mildly hormonally stimulated cycle in women with regular ovulatory cycles: a RCT. Hum Reprod. 2015; dev224.
   Web of Science ®Google Scholar
• Hu YJ, Chen YZ, Zhu YM, Huang HF. Letrozole stimulation in endometrial preparation for cryopreserved–thawed embryo transfer in women with polycystic ovarian syndrome: a pilot study. Clin Endocrinol. 2014;80:283–289. doi:10.1111/cen.12280
   PubMed Web of Science ®Google Scholar
• Cummins J, Breen T, Harrison K, Shaw J, Wilson L, Hennessey J. A formula for scoring human embryo growth rates in in vitro fertilization: its value in predicting pregnancy and in comparison with visual estimates of embryo quality. J In Vitro Fert Embryo Transfer. 1986;3:284–295. doi:10.1007/BF01133388
   PubMedGoogle Scholar
• Liu X, Xue S, Jin W, Lv Q, Peng Q, Cao S. Impact of incubation time of vitrification-warming embryos on frozen-thawed embryo transfer outcomes. J Reprod Med. 2010;19:104–107.
   Google Scholar
• Li S-J, Zhang Y-J, Chai X-S, et al. Letrozole ovulation induction: an effective option in endometrial preparation for frozen–thawed embryo transfer. Arch Gynecol Obstet. 2014;289:687–693. doi:10.1007/s00404-013-3044-024121690
   PubMed Web of Science ®Google Scholar
• Tatsumi T, Jwa SC, Kuwahara A, Irahara M, Kubota T, Saito H. Pregnancy and neonatal outcomes following letrozole use in frozen-thawed single embryo transfer cycles. Hum Reprod. 2017;32:1244–1248. doi:10.1093/humrep/dex06628398491
   PubMed Web of Science ®Google Scholar
• Tatsumi T, Jwa S, Kuwahara A, Irahara M, Kubota T, Saito H. Pregnancy and neonatal outcomes following letrozole use in frozen-thawedsingle embryo transfer cycles. Hum Reprod. 2017;32:1244‐1248. doi:10.1093/humrep/dex066
   Web of Science ®Google Scholar
• Diamond MP, Legro RS, Coutifaris C, et al. Letrozole, gonadotropin, or clomiphene for unexplained infertility. N Engl J Med. 2015;373:1230–1240. doi:10.1056/NEJMoa141482726398071
   PubMed Web of Science ®Google Scholar
• Requena A, Herrero J, Landeras J, et al. Use of letrozole in assisted reproduction: a systematic review and meta-analysis. Hum Reprod Update. 2008;14:571–582. doi:10.1093/humupd/dmn03318812422
   PubMed Web of Science ®Google Scholar
• Ganesh A, Chauhan N, Das S, Chakravarty B, Chaudhury K. Endometrial receptivity markers in infertile women stimulated with letrozole compared with clomiphene citrate and natural cycles. Syst Biol Reprod Med. 2014;60:105–111. doi:10.3109/19396368.2013.86231624304327
   PubMed Web of Science ®Google Scholar
• Miller PB, Parnell BA, Bushnell G, et al. Endometrial receptivity defects during IVF cycles with and without letrozole. Hum Reprod. 2012;27:881–888. doi:10.1093/humrep/der45222246449
   PubMed Web of Science ®Google Scholar
• Siddhartha N, Reddy NS, Pandurangi M, Tamizharasi M, Radha V, Kanimozhi K. Correlation of serum estradiol level on the day of ovulation trigger with the reproductive outcome of intracytoplasmic sperm injection. J Hum Reprod Sci. 2016;9:23. doi:10.4103/0974-1208.17863127110074
   PubMedGoogle Scholar
• Ceydeli N, Kaleli S, Calay Z, Erel CT, Akbas F, Ertungealp E. Difference in αvβ3 integrin expression in endometrial stromal cell in subgroups of women with unexplained infertility. Eur J Obstetrics Gynecol Reprod Biol. 2006;126:206–211. doi:10.1016/j.ejogrb.2005.11.034
   PubMed Web of Science ®Google Scholar
• Nardo LG, Bartoloni G, Di Mercurio S, Nardo F. Expression of αvβ3 and α4β1 integrins throughout the putative window of implantation in a cohort of healthy fertile women. Acta Obstet Gynecol Scand. 2002;81:753–758.12174161
   PubMed Web of Science ®Google Scholar
• Tei C, Maruyama T, Kuji N, Miyazaki T, Mikami M, Yoshimura Y. Reduced expression of αvβ3 integrin in the endometrium of unexplained infertility patients with recurrent IVF-ET failures: improvement by danazol treatment. J Assist Reprod Genet. 2003;20:13–20. doi:10.1023/A:102125462088812645863
   PubMed Web of Science ®Google Scholar
• Kahyaoglu S, Yumusak OH, Ozgu-Erdinc AS, et al. Can serum estradiol levels on the fourth day of IVF/ICSI cycle predict outcome in poor responder women? Syst Biol Reprod Med. 2015;61:233–237. doi:10.3109/19396368.2015.101364525671507
   PubMed Web of Science ®Google Scholar
• Melnick AP, Pereira N, Murphy EM, Rosenwaks Z, Spandorfer SD. How low is too low? Cycle day 28 estradiol levels and pregnancy outcomes. Fertil Steril. 2016;105:905–909. doi:10.1016/j.fertnstert.2015.11.04626707516
   PubMed Web of Science ®Google Scholar
• Kyrou D, Popovic-Todorovic B, Fatemi H, et al. Does the estradiol level on the day of human chorionic gonadotrophin administration have an impact on pregnancy rates in patients treated with rec-FSH/GnRH antagonist? Hum Reprod. 2009;dep290.
   Web of Science ®Google Scholar
• Zavy MT, Craig LB, Wild RA, Kahn SN, O’Leary D, Hansen KR. In high responding patients undergoing an initial IVF cycle, elevated estradiol on the day of hCG has no effect on live birth rate. Reprod Biol Endocrinol. 2014;12:1. doi:10.1186/1477-7827-12-11924383664
   PubMed Web of Science ®Google Scholar
• Anifandis G, Koutselini E, Louridas K, et al. Estradiol and leptin as conditional prognostic IVF markers. Reproduction. 2005;129:531–534. doi:10.1530/rep.1.0056715798029
   PubMed Web of Science ®Google Scholar
• Shapiro BS, Daneshmand ST, Garner FC, Aguirre M, Hudson C, Thomas S. Evidence of impaired endometrial receptivity after ovarian stimulation for in vitro fertilization: a prospective randomized trial comparing fresh and frozen–thawed embryo transfer in normal responders. Fertil Steril. 2011;96:344–348. doi:10.1016/j.fertnstert.2011.05.05021737072
   PubMed Web of Science ®Google Scholar
• Fatemi H, Popovic-Todorovic B. Implantation in assisted reproduction: a look at endometrial receptivity. Reprod biomed. 2013;27:530–538. doi:10.1016/j.rbmo.2013.05.018
   PubMed Web of Science ®Google Scholar
• Montville CP, Khabbaz M, Aubuchon M, Williams DB, Thomas MAJ. Luteal support with intravaginal progesterone increases clinical pregnancy rates in women with polycystic ovary syndrome using letrozole for ovulation induction. Fertil Steril. 2010;94:678–683. doi:10.1016/j.fertnstert.2009.03.08819515366
   PubMed Web of Science ®Google Scholar
• Elsedeek MS-E-A, Elmaghraby HA. Predictors and characteristics of letrozole induced ovulation in comparison with clomiphene induced ovulation in anovulatory PCOS women. Middle East Fert Soc J. 2011;16:125–130.
   Google Scholar
• Wang J, Wei Y, Diao F, et al. The association between polycystic ovary syndrome and ectopic pregnancy after in vitro fertilization and embryo transfer. Am J Obstetrics Gynecol. 2013;209:139.e131–139.e139. doi:10.1016/j.ajog.2013.05.007
   Web of Science ®Google Scholar
• Shao R, Feng Y, Zou S, et al. The role of estrogen in the pathophysiology of tubal ectopic pregnancy. Am J Transl Res. 2012;4:269–278.22937205
   PubMed Web of Science ®Google Scholar