192
Views
9
CrossRef citations to date
0
Altmetric
Original Research

Colon Targeting of Naringin for Enhanced Cytoprotection Against Indomethacin-Induced Colitis in Rabbits

, ORCID Icon, , &
Pages 677-696 | Published online: 19 Feb 2020

References

  • StroberW, LúdvíkssonBR, FussIJ. The pathogenesis of mucosal inflammation in murine models of inflammatory bowel disease and Crohn’s disease. Ann Intern Med. 1998;128:848–856. doi:10.7326/0003-4819-128-10-199805150-000099599198
  • HagarHH, El-MedanyA, El-EterE, ArafaM. Ameliorative effect of pyrrolidinedithiocarbamate on acetic acid-induced colitis in rats. Eur J Pharmacol. 2007;554:69–77. doi:10.1016/j.ejphar.2006.09.06617112501
  • InoueS, MatsumotoT, IidaM, et al. Characterization of cytokine expression in the rectal mucosa of ulcerative colitis: correlation with disease activity. Am J Gastroenterol. 1999;94:2441–2446. doi:10.1111/j.1572-0241.1999.01372.x10484006
  • ShanahanF. Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeutics. Gastroenterology. 2001;120:622–635. doi:10.1053/gast.2001.2212211179240
  • OgataH, HibiT. Cytokine and anti-cytokine therapies for inflammatory bowel disease. Curr Pharm Des. 2003;9:1107–1113. doi:10.2174/138161203345503512769750
  • VanamalaJ, LeonardiT, PatilBS, et al. Suppression of colon carcinogenesis by bioactive compounds in grapefruit. Carcinogenesis. 2006;27:1257–1265. doi:10.1093/carcin/bgi31816387741
  • AmaroMI, RochaJ, Vila-RealH, et al. Anti-inflammatory activity of naringin and the biosynthesised naringenin by naringinase immobilized in microstructured materials in a model of DSS-induced colitis in mice. Food Res Int. 2009;42:1010–1017. doi:10.1016/j.foodres.2009.04.016
  • ChoudhuryR, ChowrimootooG, SraiK, DebnamE, Rice-EvansCA. Interactions of the flavonoid naringenin in the gastrointestinal tract and the influence of glycosylation. Biochem Biophys Res Commun. 1999;265:410–415. doi:10.1006/bbrc.1999.169510558881
  • HsiuSL, HuangTY, HanYC, ChinDH, ChaoPD. Comparison of metabolic pharmacokinetics of naringin and naringenin in rabbits. Life Sci. 2002;70:1481–1489. doi:10.1016/S0024-3205(01)01491-611895099
  • LauroMR, De SimoneF, SansoneF, IannelliP, AquinoRP. Preparations and release characteristics of naringin and naringenin gastro-resistant microparticles by spray-drying. J Drug Del Sci Tech. 2007;17:119–124. doi:10.1016/S1773-2247(07)50018-3
  • RechnerAR, SmithMA, KuhnleG, et al. Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products. Free Radic Biol Med. 2004;36:212–225. doi:10.1016/j.freeradbiomed.2003.09.02214744633
  • SalaritabarA, DarvishiB, HadjiakhoondiF, et al. Therapeutic potential of flavonoids in inflammatory bowel disease: a comprehensive review. World J Gastroenterol. 2017;23(28):5097–5114. doi:10.3748/wjg.v23.i28.509728811706
  • KumarVS, RajmaneAR, AdilM, KandhareAD, GhoshP, BodhankarSL. Naringin ameliorates acetic acid induced colitis through modulation of endogenous oxido-nitrosative balance and DNA damage in rats. J Biomed Res. 2014;28:132–145. doi:10.7555/JBR.27.2012008224683411
  • AkalaEO, ElekwachiO, ChaseV, JohnsonH, LazarreM, ScottK. Organic redox initiated polymerization process for the fabrication of hydrogel for colon specific drug delivery. Drug Dev Ind Pharm. 2003;29:375–386. doi:10.1081/DDC-12001837312737531
  • OrluM, CevherE, AramanA. Design and evaluation of colon specific drug delivery system containing flurbiprofen microsponges. Int J Pharm. 2006;318:103–117. doi:10.1016/j.ijpharm.2006.03.02516687222
  • KarroutY, NeutC, WilsD, et al. Novel polymeric film coatings for colon targeting: how to adjust desired membrane properties. Int J Pharm. 2009;371:64–70. doi:10.1016/j.ijpharm.2008.12.01419135511
  • YangL, ChuJS, FixJA. Colon-specific drug delivery: new approaches and in vitro/in vivo evaluation. Int J Pharm. 2002;235:1–15. doi:10.1016/S0378-5173(02)00004-211879735
  • SinghBN. Modified-release solid formulations for colonic delivery. Recent Pat Drug Deliv Formul. 2007;1:53–63. doi:10.2174/18722110777981412219075874
  • AshfordM, FellJ, AttwoodD, SharmaH, WoodheadP. An evaluation of pectin as a carrier for drug targeting to the colon. J Control Release. 1993;26:213–220. doi:10.1016/0168-3659(93)90188-B
  • KenyonCJ, ColeET, WildingIR. The effect of food on the in vivo behaviour of enteric coated starch capsules. Int J Pharm. 1997;112:207–213.
  • GuptaVK, BeckertTE, PriceJC. A novel pH- and time-based multi-unit potential colonic drug delivery system. I. Development. Int J Pharm. 2001;213:83–91. doi:10.1016/S0378-5173(00)00649-911165096
  • RujivipatS, BodmeierR. Improved drug delivery to the lower intestinal tract with tablets compression-coated with enteric/nonenteric polymer powder blends. Eur J Pharm Biopharm. 2010;76:486–492. doi:10.1016/j.ejpb.2010.09.00420868750
  • VemulaSK, VeerareddyPR, DevadasuVR. Pharmacokinetics of colon-specific pH and time-dependent flurbiprofen tablets. Eur J Drug Metab Pharmacokinet. 2015;40:301–3011. doi:10.1007/s13318-014-0210-024916715
  • EmejeM, NwabunikeP, IsimiY, KunleO, OfoefuleS. Preparation and evaluation of colon targeted drug delivery systems for albendazole using kneading, extrusion and compaction technology. Yao Xue Xue Bao. 2009;44:1152–1158.20055141
  • VemulaSK, VeerareddyPR. Development, evaluation and pharmacokinetics of time-dependent ketorolac tromethamine tablets. Exp Opin Drug Deliv. 2013;10:33–45. doi:10.1517/17425247.2013.743528
  • BorgTM, MohamedEA, El NaggarEE, El-SheakhAR, HamedMF. Colon targeting of naringin for cytoprotection against ulcerative colitis: in vitro-in vivo study. IOSR-JPBS. 2017;12(2):23–29.
  • PagetGE, BarnesJM. Evaluation of drug activities In: LaurenceDR, BacharachAL, editors. Pharmacometrics. London: Academic Press; 1964:1–50.
  • The United States Pharmacopoeial Convention. The United States Pharmacopeia 28th, the National Formulary 23rd. Washington: The United States Pharmacopoeial Convention Inc.; 2005.
  • LateS, BangaA. Thermal and non-thermal methods to evaluate compatibility of granisetron hydrochloride with tablet excipients. Pharmazie. 2008;63:453–458.18604989
  • TadrosMI. Controlled-release effervescent floating matrix tablets of ciprofloxacin hydrochloride: development, optimization and in vitro-in vivo evaluation in healthy human volunteers. Eur J Pharm Biopharm. 2010;74:332–339. doi:10.1016/j.ejpb.2009.11.01019932750
  • YusifRM, Abu HashimII, MohamedEA, BadriaFA. Gastroretentive matrix tablets of Boswellia Oleogum resin: preparation, optimization, in vitro evaluation, and cytoprotective effect on indomethacin-induced gastric ulcer in rabbits. AAPS PharmSciTech. 2016;17:328–338. doi:10.2147/IJN.S15432526092303
  • YehiaSA, ElshafeeyAH, SayedAH. Optimization of budesonide compression-coated tablets for colonic delivery. AAPS PharmSciTech. 2009;10:147–157. doi:10.1208/s12249-009-9188-319199041
  • KrishnaiahYS, Bhaskar ReddyPR, SatyanarayanaV, KarthikeyanRS. Studies on the development of oral colon targeted drug delivery systems for metronidazole in the treatment of amoebiasis. Int J Pharm. 2002;236:43–55. doi:10.1016/S0378-5173(02)00006-611891069
  • AkhgariA, SadeghiF, Afrasiabi GarekaniH. Combination of time-dependent and pH-dependent polymethacrylates as a single coating formulation for colonic delivery of indomethacin pellets. Int J Pharm. 2006;320:137–142. doi:10.1016/j.ijpharm.2006.05.01116782290
  • MartinA, BustamanteP, ChunAHC. Kinetics In: Physical Pharmacy. 4th ed. Philadelphia: Lea and Febiger; 1993:284–323.
  • HiguchiT. Mechanism of rate of sustained-action medication: the theoretical analysis of rate of release of solid drug dispersed in solid matrices. J Pharm Sci. 1963;52:1145–1149. doi:10.1002/jps.260052121014088963
  • RitgerPL, PeppasNA. A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J Control Release. 1987;5:23–36. doi:10.1016/0168-3659(87)90034-4
  • PercyWH, BurtonMB, FallickF, BurakoffRA. comparison in vitro of human and rabbit distal colonic muscle responses to inflammatory mediators. Gastroenterology. 1990;99:1324–1332. doi:10.1016/0016-5085(90)91157-22210241
  • WangaW, LiuQ, WangaC, MengaQ, KakuT, LiuK. Effects of JBP485 on the expression and function of PEPT1 in indomethacin-induced intestinal injury in rats and damage in Caco-2 cells. Peptides. 2011;32:946–955. doi:10.1016/j.peptides.2011.01.03121310202
  • Reagn-shawS, NihalM, AhmadN. Dose translation from animal to human studies revisited. FASEB J. 2007;22:659–661. doi:10.1096/fj.07-9574LSF17942826
  • NairAB, JacobS. A simple practice guide for dose conversion between animals and human. J Basic Clin Pharma. 2016;7:27–31. doi:10.4103/0976-0105.177703
  • SharmaPR, LewisSA. Design and in vitro/in vivo evaluation of extended release matrix tablets of nateglinide. J Young Pharm. 2013;5:167–172. doi:10.1016/j.jyp.2013.11.00324563597
  • ShehatouGS, SuddekGM. Sulforaphane attenuates the development of atherosclerosis and improves endothelial dysfunction in hypercholesterolemic rabbits. Exp Biol Med (Maywood). 2016;241(4):426–436. doi:10.1177/153537021560969526490346
  • OdaT. Role of mast cells in dextran sulfate sodium-induced experimental colitis in rats. J Kyoto Pref Univ Med. 1995;104:1069–1082.
  • ArakiY, AndohA, FujiyamaY, BambaT. Development of dextran sulphate sodium-induced experimental colitis is suppressed in genetically mast cell-deficient Ws/Ws rats. Clin Exp Immunol. 2000;119:264–269. doi:10.1046/j.1365-2249.2000.01094.x10632661
  • AustinGL, HerfarthHH, SandlerRS. A critical evaluation of serologic markers for inflammatory bowel disease. Clin Gastroenterol Hepatol. 2007;5:545–547. doi:10.1016/j.cgh.2007.03.00617433787
  • RuemmeleFM, TarganSR, LevyG, DubinskyM, BraunJ, SeidmanEG. Diagnostic accuracy of serological assays in pediatric inflammatory bowel disease. Gastroenterology. 1998;115:822–829. doi:10.1016/s0016-5085(98)70252-59753483
  • LewisJD. The utility of biomarkers in the diagnosis and therapy of inflammatory bowel disease. Gastroenterology. 2011;140:1817–1826. doi:10.1053/j.gastro.2010.11.05821530748
  • El-SheakhAR, SuddekGM. Ammarel-SM. Antioxidant and anti-inflammatory effects of flavocoxid in high-cholesterol-fed rabbits. Naunyn Schmiedebergs Arch Pharmacol. 2015;388:1333–1344.26341793
  • MohamedEA, Abu HashimII, YusifRM, et al. Polymeric micelles for potentiated antiulcer and anticancer activities of naringin. Int J Nanomedicine. 2018;13:1009–1027.29497294
  • AbdelazizHA, ShakerME, HamedMF, GameilNM. Repression of acetaminophen-induced hepatotoxicity by a combination of celastrol and brilliant blue G. Toxicol Lett. 2017;275:6–18. doi:10.1016/j.toxlet.2017.04.01228435131
  • SahuN, SoniD, ChandrashekharB. Synthesis of silver nanoparticles using flavonoids: hesperidin, naringin and diosmin, and their antibacterial effects and cytotoxicity. Int Nano Lett. 2016;6:173–181.
  • FicarraR, TommasiniS, RaneriD, et al. Study of flavonoids/β-cyclodextrins inclusion complexes by NMR, FT-IR, DSC, X-ray investigation. J Pharm Biomed Anal. 2002;29:1005–1014.12110385
  • CordenonsiLM, SponchiadoRM, CampanharoSC, et al. Study of flavonoids present in Pomelo (Citrus máxima) by DSC, UV-VIS, IR, 1H AND 13C NMR AND MS. Drug Anal. Res. 2017;1:31–37.
  • ShenX, YuD, ZhuL, Branford-WhiteC, WhiteK, ChattertonNP. Electrospun diclofenac sodium loaded Eudragit® L 100-55 nanofibers for colon-targeted drug delivery. Int J Pharm. 2011;408:200–207. doi:10.1016/j.ijpharm.2011.01.05821291969
  • DesaiJ, AlexanderK, RigaA. Characterization of polymeric dispersions of dimenhydrinate in ethyl cellulose for controlled release. Int J Pharm. 2006;308:115–123. doi:10.1016/j.ijpharm.2005.10.03416326055
  • SmithaB, SridharS, KhanAA. Chitosan–sodium alginate polyion complexes as fuel cell membranes. J Eur Polym. 2005;41:1859–1866. doi:10.1016/j.eurpolymj.2005.02.018
  • BaoY, MaJ, LiN. Synthesis and swelling behaviors of sodium carboxymethyl cellulose-g-poly(AA-co-AM-co-AMPS)/MMT superabsorbent hydrogel. Carbohydr Polym. 2011;84:76–82.
  • CuiL, ZhangZH, SunE, JiaXB. Effect of β-cyclodextrin complexation on solubility and enzymatic conversion of naringin. Int J Mol Sci. 2012;13:14251–14261. doi:10.3390/ijms13111425123203062
  • LiuJ, CaoF, ZhangC, PingQ. Use of polymer combinations in the preparation of solid dispersions of a thermally unstable drug by hot-melt extrusion. Acta Pharm Sin B. 2013;3:263–272. doi:10.1016/j.apsb.2013.06.007
  • González-RodríguezM, HolgadoM, Sánchez-LafuenteC, RabascoA, FiniA. Alginate/chitosan particulate systems for sodium diclofenac release. Int J Pharm. 2002;232:225–234. doi:10.1016/S0378-5173(01)00915-211790506
  • SoaresJP, SantosJE, ChiericeGO, CavalheiroETG. Thermal behavior of alginic acid and its sodium salt. Eclética Química. 2004;29:57–64. doi:10.1590/S0100-46702004000200009
  • JanaS, Kumar TrivediM, TallapragadaRM. Characterization of physicochemical and thermal properties of chitosan and sodium alginate after biofield treatment. Pharm Anal Acta. 2015;6:1–9.
  • El-SayedS, MahmoudKH, FatahAA, DSCHA. TGA and dielectric properties of carboxymethyl cellulose/polyvinyl alcohol blends. Physica B Condens Matter. 2011;406:4068–4076. doi:10.1016/j.physb.2011.07.050
  • Abu HashimII, HigashiT, AnnoT, et al. Potential use of gamma-cyclodextrin polypseudorotaxane hydrogels as an injectable sustained release system for insulin. Int J Pharm. 2010;392:83–91. doi:10.1016/j.ijpharm.2010.03.02620298768
  • PrasadYV, KrishnaiahYS, SatyanarayanaS. In vitro evaluation of guar gum as a carrier for colon-specific drug delivery. J Control Release. 1998;51:281–287. doi:10.1016/S0168-3659(97)00181-89685926
  • AsgharLF, ChureCB, ChandranS. Colon specific delivery of indomethacin: effect of incorporating pH sensitive polymers in xanthan gum matrix bases. AAPS PharmSciTech. 2009;10:418–429. doi:10.1208/s12249-009-9223-419381832
  • MirshafieyA, KhodadadiA, RehmBH, et al. Sodium alginate as a novel therapeutic option in experimental colitis. Scand J Immunol. 2005;61:316–321. doi:10.1111/j.1365-3083.2005.01571.x15853913
  • CohavyO, BrucknerD, GordonLK, et al. Colonic bacteria express an ulcerative colitis pANCA-related protein epitope. Infect Immun. 2000;68(3):1542–1548. doi:10.1128/IAI.68.3.1542-1548.200010678972
  • RoglerG, AndusT. Cytokines in inflammatory bowel disease. World J Surg. 1998;22:382–389. doi:10.1007/s0026899004019523521
  • SandsBE, KaplanGG. The role of TNF alpha in ulcerative colitis. J Clin Pharmacol. 2007;47(8):930–941. doi:10.1177/009127000730162317567930