Hongjingtian Injection Inhibits Proliferation and Migration and Promotes Apoptosis in High Glucose-Induced Vascular Smooth Muscle Cells

References

• Cho NH, Shaw JE, Karuranga S, et al. IDF diabetes atlas: global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract. 2018;138:271–281. doi:10.1016/j.diabres.2018.02.02329496507
   PubMed Web of Science ®Google Scholar
• Maric-Bilkan C. Sex differences in micro- and macro-vascular complications of diabetes mellitus. Clin Sci (Lond). 2017;131(9):833–846. doi:10.1042/CS2016099828424377
   PubMed Web of Science ®Google Scholar
• Katakami N. Mechanism of development of atherosclerosis and cardiovascular disease in diabetes mellitus. J Atheroscler Thromb. 2018;25(1):27–39. doi:10.5551/jat.RV1701428966336
   PubMed Web of Science ®Google Scholar
• Shi N, Chen SY. Smooth muscle cell differentiation: model systems, regulatory mechanisms, and vascular diseases. J Cell Physiol. 2016;231(4):777–787. doi:10.1002/jcp.2520826425843
   PubMed Web of Science ®Google Scholar
• Allen DA, Yaqoob MM, Harwood SM. Mechanisms of high glucose-induced apoptosis and its relationship to diabetic complications. J Nutr Biochem. 2005;16(12):705–713. doi:10.1016/j.jnutbio.2005.06.00716169208
   PubMed Web of Science ®Google Scholar
• Rudijanto A. The role of vascular smooth muscle cells on the pathogenesis of atherosclerosis. Acta Med Indones. 2007;39(2):7.
   Google Scholar
• Shi H, Wang D, Zhao D, Liu G. Study on the influence of serum hs-CRP and AS in patients with Primary Hypertension with Sofren injection. Cardiovasc Dis J Integr Tradit Chin West Med. 2015;3(10):3.
   Google Scholar
• Zhao J, Liao Y, Chen S. Effect of Dazhu Hongjingtian injection on hemorrheology in type 2 diabetes. Clini J Chin Med. 2016;8:2.
   Google Scholar
• Ma YM, Zhang XZ, Su ZZ, et al. Insight into the molecular mechanism of a herbal injection by integrating network pharmacology and in vitro. J Ethnopharmacol. 2015;173:91–99. doi:10.1016/j.jep.2015.07.01626192807
   PubMed Web of Science ®Google Scholar
• Liu Y, Chen C, Qiu J, et al. Characterization of the chemical constituents in Hongjingtian injection by liquid chromatography quadrupole time-of-flight mass spectrometry. Biomed Chromatogr. 2019;33(3):e4446. doi:10.1002/bmc.v33.330468269
   PubMed Web of Science ®Google Scholar
• Yang S, Zhao G, Wang R, et al. Study on fingerprint of Hongjingtian injection by HPLC. J Tianjin Med Univ. 2016;22:164–167.
   Google Scholar
• Wang L, Zhang Z, Liang L, Wu Y, Zhong J, Sun X. Anti-high mobility group box-1 antibody attenuated vascular smooth muscle cell phenotypic switching and vascular remodelling after subarachnoid haemorrhage in rats. Neurosci Lett. 2019;708:134338. doi:10.1016/j.neulet.2019.13433831226363
   PubMed Web of Science ®Google Scholar
• He X, Jiang H, Gao F, Liang S, Wei M, Chen L. Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-kappaB signaling pathway. Microsc Res Tech. 2019. doi:10.1002/jemt.23369
   PubMed Web of Science ®Google Scholar
• Han Y, Jiang Q, Wang Y, et al. The anti-proliferative effects of oleanolic acid on A7r5 cells-Role of UCP2 and downstream FGF-2/p53/TSP-1. Cell Biol Int. 2017;41(12):1296–1306. doi:10.1002/cbin.v41.1228792088
   PubMed Web of Science ®Google Scholar
• Zhang S, Zhang L, Zhang H, et al. Hongjingtian injection attenuates myocardial oxidative damage via promoting autophagy and inhibiting apoptosis. Oxid Med Cell Longev. 2017;2017:6965739. doi:10.1155/2017/696573928804535
   PubMed Web of Science ®Google Scholar
• Liu Y, Li X, Jiang S, Ge Q. Tetramethylpyrazine protects against high glucose-induced vascular smooth muscle cell injury through inhibiting the phosphorylation of JNK, p38MAPK, and ERK. J Int Med Res. 2018;46(8):3318–3326. doi:10.1177/030006051878170529996693
   PubMed Web of Science ®Google Scholar
• Xing X, Chen S, Li L, et al. The active components of Fuzheng Huayu formula and their potential mechanism of action in inhibiting the hepatic stellate cells viability - a network pharmacology and transcriptomics approach. Front Pharmacol. 2018;9:525. doi:10.3389/fphar.2018.0052529881350
   PubMed Web of Science ®Google Scholar
• Cai W, Zhang J, Yang J, et al. MicroRNA-24 attenuates vascular remodeling in diabetic rats through PI3K/Akt signaling pathway. Nutr Metab Cardiovasc Dis. 2019;29(6):11. doi:10.1016/j.numecd.2019.03.002
   Web of Science ®Google Scholar
• Manfe V, Biskup E, Rosbjerg A, et al. miR-122 regulates p53/Akt signalling and the chemotherapy-induced apoptosis in cutaneous T-cell lymphoma. PLoS One. 2012;7(1):e29541. doi:10.1371/journal.pone.002954122235305
   PubMed Web of Science ®Google Scholar
• Shi L, Ji Y, Jiang X, et al. Liraglutide attenuates high glucose-induced abnormal cell migration, proliferation, and apoptosis of vascular smooth muscle cells by activating the GLP-1 receptor, and inhibiting ERK1/2 and PI3K/Akt signaling pathways. Cardiovasc Diabetol. 2015;14:18. doi:10.1186/s12933-015-0177-425855361
   PubMed Web of Science ®Google Scholar
• Wang K, Deng X, Shen Z, et al. High glucose promotes vascular smooth muscle cell proliferation by upregulating proto-oncogene serine/threonine-protein kinase Pim-1 expression. Oncotarget. 2017;8(51):88320–88331. doi:10.18632/oncotarget.1936829179437
   PubMedGoogle Scholar
• Baumer Y, McCurdy S, Alcala M, et al. CD98 regulates vascular smooth muscle cell proliferation in atherosclerosis. Atherosclerosis. 2017;256:105–114. doi:10.1016/j.atherosclerosis.2016.11.01728012647
   PubMed Web of Science ®Google Scholar
• Sun X, Liu Y, Jiang D, Chen F, Xie Y, Sun Y. Research progress on the pharmacological effects of Rhodiola rosea. Acta Chin Med Pharmacol. 2017;45(6):4.
   Google Scholar
• Zhuang X, Maimaitijiang A, Li Y, Shi H, Jiang X. Salidroside inhibits high-glucose induced proliferation of vascular smooth muscle cells via inhibiting mitochondrial fission and oxidative stress. Exp Ther Med. 2017;14(1):515–524. doi:10.3892/etm.2017.454128672961
   PubMed Web of Science ®Google Scholar
• Yang Z, Xiong K, Qi P, et al. Gallic acid tailoring surface functionalities of plasma-polymerized allylamine-coated 316L SS to selectively direct vascular endothelial and smooth muscle cell fate for enhanced endothelialization. ACS Appl Mater Interfaces. 2014;6(4):2647–2656. doi:10.1021/am405124z24484285
   PubMed Web of Science ®Google Scholar
• Vivancos M, Moreno JJ. Effect of resveratrol, tyrosol and beta-sitosterol on oxidised low-density lipoprotein-stimulated oxidative stress, arachidonic acid release and prostaglandin E2 synthesis by RAW 264.7 macrophages. Br J Nutr. 2008;99(6):1199–1207. doi:10.1017/S000711450787620318081942
   PubMed Web of Science ®Google Scholar
• Behrangi N, Namvar N, Ataei M, Dizaji S, Javdani G, MH S. MMP9 gene expression variation by ingesting tart cherry and P-coumaric acid during remyelination in the cuprizone mouse model. Acta Med Iran. 2017;55(9):10.
   Google Scholar
• Gao L, Wang KX, Zhou YZ, Fang JS, Qin XM, Du GH. Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation. Sci Rep. 2018;8(1):624. doi:10.1038/s41598-017-18325-729330507
   PubMed Web of Science ®Google Scholar
• Lee AY, Park W, Kang TW, Cha MH, Chun JM. Network pharmacology-based prediction of active compounds and molecular targets in Yijin-Tang acting on hyperlipidaemia and atherosclerosis. J Ethnopharmacol. 2018;221:151–159. doi:10.1016/j.jep.2018.04.02729698773
   PubMed Web of Science ®Google Scholar
• Epand RM. Features of the phosphatidylinositol cycle and its role in signal transduction. J Membr Biol. 2017;250(4):353–366. doi:10.1007/s00232-016-9909-y27278236
   PubMed Web of Science ®Google Scholar
• Zhang C-Y, Yu M-S, Li X, Zhang Z, Han C-R, Yan B. Overexpression of long non-coding RNA MEG3 suppresses breast cancer cell proliferation, invasion, and angiogenesis through AKT pathway. Tumor Biol. 2017;39(6):1010428317701311.
   Google Scholar
• Xu W, Gao L, Li T, Zheng J, Shao A, Zhang J. Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) protects against neuronal apoptosis via activation of Akt/MDM2/p53 signaling pathway in a rat model of intracerebral hemorrhage. Front Mol Neurosci. 2018;11. doi:10.3389/fnmol.2018.00176
   Web of Science ®Google Scholar
• Newby AC. Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. Cardiovasc Res. 2006;69(3):614–624. doi:10.1016/j.cardiores.2005.08.00216266693
   PubMed Web of Science ®Google Scholar
• Shankar S, Srivastava RK. Involvement of Bcl-2 family members, phosphatidylinositol 3ʹ-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer. Int J Oncol. 2007;30(4):905–918.17332930
   PubMed Web of Science ®Google Scholar
• Vousden KH, Lu X. Live or let die: the cell’s response to p53. Nat Rev Cancer. 2002;2(8):594–604. doi:10.1038/nrc86412154352
   PubMed Web of Science ®Google Scholar
• Tait SW, Green DR. Mitochondrial regulation of cell death. Cold Spring Harb Perspect Biol. 2013;5(9):a008706–a008706. doi:10.1101/cshperspect.a00870624003207
   PubMed Web of Science ®Google Scholar
• Ashkenazi A, Dixit VM. Death receptors: signaling and modulation. Science. 1998;281(5381):1305–1308. doi:10.1126/science.281.5381.13059721089
   PubMed Web of Science ®Google Scholar