102
Views
9
CrossRef citations to date
0
Altmetric
Original Research

Muscone Promotes The Adipogenic Differentiation Of Human Gingival Mesenchymal Stem Cells By Inhibiting The Wnt/β-Catenin Signaling Pathway

, , , , , & show all
Pages 3291-3306 | Published online: 18 Sep 2019

References

  • Heo JS, Choi Y, Kim HS, Kim HO. Comparison of molecular profiles of human mesenchymal stem cells derived from bone marrow, umbilical cord blood, placenta and adipose tissue. Int J Mol Med. 2016;37:115–125. doi:10.3892/ijmm.2015.241326719857
  • Inzana JA, Olvera D, Fuller SM, et al. 3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration. Biometerial. 2014;35:4026–4034. doi:10.1016/j.biomaterials.2014.01.064
  • Bartold PM, McCulloch CA, Narayanan AS, Pitaru S. Tissue engineering: A new paradigm for periodontal regeneration based on molecular and cell biology. Periodontol. 2000;253–269. doi:10.1034/j.1600-0757.2000.2240113.x
  • Eid AA, Hussein KA, Niu LN, et al. Effects of tricalcium silicate cements on osteogenic differentiation of human bone marrowderived mesenchymal stem cells in vitro. Acta Biomater. 2014;10:3327–3334. doi:10.1016/j.actbio.2014.04.00624726977
  • Açil Y, Zhang X, Nitsche T, et al. Effects of different scaffolds on rat adipose tissue derived stroma cells. J Craniomaxillofac Surg. 2014;42:825–834. doi:10.1016/j.jcms.2013.11.02024411468
  • De Coppi P, Bartsch G Jr, Siddiqui MM, et al. Isolation of amniotic stem cell lines with potential for therapy. Nat Biotechnol. 2007;25:100–106. doi:10.1038/nbt127417206138
  • Tomar GB, Srivastava RK, Gupta N, et al. Human gingiva-derived mesenchymal stem cells are superior to bone marrow-derived mesenchymal stem cells for cell therapy in regenerative medicine. Biochem Biophys Res Commun. 2010;393:377–383. doi:10.1016/j.bbrc.2010.01.12620138833
  • Zhang Q, Shi S, Liu Y, et al. Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis. J Immunol. 2009;183:7787–7798. doi:10.4049/jimmunol.090083819923445
  • Zhang QZ, Nguyen AL, Yu WH, Le AD. Human oral mucosa and gingiva: a unique reservoir for mesenchymal stem cells. J Dent Res. 2012;91:1011–1018. doi:10.1177/002203451246101622988012
  • Mitrano TI, Grob MS, Carrión F, et al. Culture and characterization of mesenchymal stem cells from human gingival tissue. J Periodontol. 2010;81:917–925. doi:10.1902/jop.2010.09056620450355
  • Fawzy El-Sayed KM, Paris S, Becker ST, et al. Periodontal regeneration employing gingival margin-derived stem/progenitor cells: an animal study. J Clin Peridontol. 2012;39:861–870. doi:10.1111/j.1600-051X.2012.01904.x
  • Ye SQ. Chinese medicine gem-musk. Fam Med. 2005;5:55.
  • Zhang S. Comparative study of cytotoxicity of moschus and muscone on rat retinal neurons in vitro. Nat Prod Res Dev. 2007;19:639–641.
  • Zheng LC. Clinical application and curative effect of musk heart protecting pill. Med Info. 2009;22:2964.
  • Cao XH. Research progress on the anti-inflammatory effect of musk. China Pharmacy. 2007;18:1662–1664.
  • Li BY. Effects of musk on brain injury in mice. Int J Traditional Chin Med. 1996;18B:33–38.
  • Jiang ZY, Li CD, Zhou D, Zhou DR. Protective effect of musk on experimental cerebral ischemic neuron injury in rats. Chin J Traditional Med Sci Technol. 2001;8:96–97.
  • Shen Q, Liu YM. The clinical application and pharmacological effect of musk in nervous system diseases. Chin J Integr Med Cardio Cerebrovascul Dis. 2003;1:217–219.
  • Shun MH, Si LQ, Yin XZ. Advances in new formulations of natural antitumor drugs. China Pharmacist. 2004;7:171–173.
  • Li XT. Gene Engineering Expression of Musk Active Polypeptides [D]. Guangdong province, China: Sun yat-sen university; 2007.
  • Hou FY, Xie XW, Xi FQ, Xu SH, Li SH, Song M. Efects of muscone-containing serum on proliferation and diferentiation of rat mesenchymal stem cells. J Xian Jiaotong Univ. 2013;34:110–114.
  • Xie XW, Hou FY, Li N, Li SH, Song M. Effects of musk ketone at different concentrations on in vivo migration of exogenous rat bone marrow mesenchymal stem cells. Chin J Integr Traditional West Med. 2012;32:980–985.
  • Gruber J, Yee Z, Tolwinski NS. Developmental drift and the role of Wnt signaling in aging. Cancers. 2016;8:73. doi:10.3390/cancers8080073
  • Kaur P, Jin H, Lusk J, Tolwinski N. Modeling the role of wnt signaling in human and drosophila stem cells. Genes. 2018;9:101. doi:10.3390/genes9020101
  • Boland GM, Perkins G, Hall DJ, et al. Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells. J Cell Biochem. 2004;93(6):1210–1230. doi:10.1002/jcb.2028415486964
  • Ross SE, Hemati N, Longo KA, et al. Inhibition of adipogenes is by Wnt signaling. Science. 2000;289(5481):950–953. doi:10.1126/science.289.5481.95010937998
  • Du L, Yang P, Ge S. Isolation and characterization of human gingiva-derived mesenchymal stem cells using limiting dilution method. J Dent Sci. 2016;11:304–314. doi:10.1016/j.jds.2016.03.01030894989
  • Fathi E, FarahzadiID R, Valipour B, et al. Cytokines secreted from bone marrow derived mesenchymal stem cells promote apoptosis and change cell cycle distribution of K562 cell line as clinical agent in cell transplantation. PLoS One. 2019;14(4):e0215678. doi:10.1371/journal.pone.021567831009502
  • Fathia E, Farahzadib R, Sheikhzadehc N. Immunophenotypic characterization, multi-lineage differentiation and aging of zebrafish heart and liver tissue-derived mesenchymal stem cells as a novel approach in stem cell-based therapy. Tissue Cell. 2019;57:15–21. doi:10.1016/j.tice.2019.01.00630947959
  • Farahzadi R, Fathic E, Mesbah-Namin SA, et al. Anti-aging protective effect of L-carnitine as clinical agent in regenerative medicine through increasing telomerase activity and change in the hTERT promoter CpG island methylation status of adipose tissue-derived mesenchymal stem cells. Tissue Cell. 2018;54:105–113. doi:10.1016/j.tice.2018.08.01230309499
  • Du Y, Xin G, Meng H, et al. Muscone improves cardiac function in mice after myocardial infarction by alleviating cardiac macrophage-mediated chronic inflammation through inhibition of NF-κB and NLRP3 inflammasome. Am J Transl Res. 2018;10(12):4235–4246.30662666
  • Guoa Y-J, Luoc S-H, Tanga M-J, et al. Muscone exerts protective roles on alcohol-induced osteonecrosis of the femoral head. Biomed Pharmacother. 2018;97:825–832. doi:10.1016/j.biopha.2017.11.02529136757
  • Fournier BP, Ferre FC, Couty L, et al. Multipotent progenitor cells in gingival connective tissue. Tissue Eng Part A. 2010;16:2891–2899. doi:10.1089/ten.TEA.2009.079620412029
  • Treves-Manusevitz S, Hoz L, Rachima H, et al. Stem cells of the lamina propria of human oral mucosa and gingiva develop into mineralized tissues in vivo. J Clin Periodontol. 2013;40:73–81. doi:10.1111/jcpe.1201623137193
  • Seo BM, Miura M, Gronthos S, et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet. 2004;364:149–155. doi:10.1016/S0140-6736(04)16627-015246727
  • Bm S, Miura M, Sonoyama W, Coppe C, Stanyon R, Shi S. Recovery of stem cells from cryopreserved periodontal ligament. J Dent Res. 2005;84:907–912. doi:10.1177/15440591050840100716183789
  • Dominici M, Le Blanc K, Mueller I, et al. Minimal criteria for defining multipotent mesenchymal stromal cell. The International society for cellular therapy positionstatement. Cytotherapy. 2006;8:315–317. doi:10.1080/1465324060085590516923606
  • Keatinga A. Mesenchymal stromal cells: newdirections. Cell Stem Cell. 2012;10:709–716. doi:10.1016/j.stem.2012.05.01522704511
  • Cho KA, Park M, Kim YH. Th17 cell-mediated immune responses promote mast cell proliferation by triggering stem cell factor in keratinocytes. Biochem Biophys Res Commun. 2017. in press. doi:10.1016/j.bbrc.2017.04.141
  • Zhuo HL, Bai LP, Liu D. Effects of retinol on expressions of epidermal growth factor, stem cell factor, colony-stimulating factor 1 and leukemia inhibitory factor in human umbilical cord-derived mesenchymal stem cells. Nan Fang Yi Ke Da Xue Xue Bao. 2016;37(2):221–225.28219867
  • Yang TY. Correlation of Musk Ketone on Osteogenic Differentiation of Human Periodontal Stem Cells [D]. Jilin province, China: Jilin university; 2015.
  • Aronow MA, Gerstenfeld LC, Owen TA, Tassinari MS, Stein GS, Lian JB. Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cell. J Cell Physiol. 1990;143:213–221. doi:10.1002/jcp.10414302032332447
  • Dereka XE, Markopoulou CE, Mamalis A, Vrotsos IA. Effect of rhBMP-7 combined with two bone grafts on human periodontal ligament cell differentiation. Growth Factor. 2009;27:274–279. doi:10.1080/08977190903112721
  • Garin-Shkolnik T, Rudich A, Hotamisligil GS, Rubinstein M. FABP4 attenuates PPAR-r and adipogenesis and is inversely correlated with PPAR-r in adipose tissues. Diabetes. 2014;63:900–911. doi:10.2337/db13-043624319114
  • Rosen ED, Spiegelman BM. What we talk about when we talk about fat. Cell. 2014;156(1–2):20–44. doi:10.1016/j.cell.2013.12.01224439368
  • Hu L, Yang G, Hägg D, et al. IGF1 promotes adipogenesis by a lineage bias of endogenous adipose stem/progenitor cells. Stem Cells. 2015;33(8):2483–2495.41. doi:10.1002/stem.2052 Logan C, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004; 20: 781⁃810.26010009
  • Walton RL, Beahm EK, Wu L. Denovo adipose formation in a vascularized engineered construct. Microsurgery. 2004;24(5):378–384. doi:10.1002/micr.2005615378584
  • Lee CH, Cook JL, Mendelson A, Moioli EK, Yao H, Mao JJ. Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study. Lancet. 2010;376(9739):440–448. doi:10.1016/S0140-6736(10)60668-X20692530
  • Liu P, Feng Y, Dong C, et al. Administration of BMSCs with muscone in rats with gentamincin-induced AKI improves their therapeutic efficacy. PLoS One. 2013;9:e97123. doi:10.1371/journal.pone.0097123
  • Rao TP, Kuhl M. An updated overview on Wnt signaling pathways: a prelude for more. Circ Res. 1798–1806;106:2010.
  • Bienz M, Clevers H. Armadillo/beta-catenin signals in the nucleus–proof beyond a reasonable doubt? Nat. Cell Biol. 2003;5:179–182.
  • Clevers H, Nusse R. Wnt/beta-catenin signaling and disease. Cell. 2012;149:1192e1205. doi:10.1016/j.cell.2012.05.01222682243
  • Moldes M, Zuo Y, Morrison RF. Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling dur-ing adipogenesis. Biochem J. 2003;376:607–613. doi:10.1042/bj20030426
  • Li PH, Liu YY, Cui L. Regulating effects of Wnt signaling pathway on differentiation of bone marrow mesenchymal stem cells into osteoblasts and adipocytes. Chin J Tiissue Engg Res. 2010;14:1749⁃1754.
  • Gaur T, Lengner CJ, Hovhannisyan H, et al. Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression. J Biol Chem. 2005;280:33132–33140. doi:10.1074/jbc.M50060820016043491
  • Bennett CN, Longo KA, Wright WS, et al. Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci USA. 2005;102:3324–3329. doi:10.1073/pnas.040874210215728361
  • Bennett CN, Longo KA, Wright WS, et al. Regulation of Wnt signaling during adipogenesis. J Biolchem. 2000;277:30998–31004.
  • Stamboloc V, Ruel L, Woodgett JR. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells. Curr Biol. 1996;6:1664–1668. doi:10.1016/s0960-9822(02)70790-28994831