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Original Research

MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-κB Signaling Pathway

, , , , , , & show all
Pages 1377-1389 | Published online: 05 Apr 2020

References

  • LoveS. Demyelinating diseases. J Clin Pathol. 2006;59(11):1151–1159. doi:10.1136/jcp.2005.03119517071802
  • PopescuBF, LucchinettiCF. Pathology of demyelinating diseases. Annu Rev Pathol. 2012;7:185–217. doi:10.1146/annurev-pathol-011811-13244322313379
  • WeinshenkerBG, BassB, RiceGP, et al. The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability. Brain. 1989;112(Pt 1):133–146. doi:10.1093/brain/112.1.1332917275
  • WangD, DongX, WangC. Honokiol ameliorates amyloidosis and neuroinflammation and improves cognitive impairment in alzheimer’s disease transgenic mice. J Pharmacol Exp Ther. 2018;366(3):470–478. doi:10.1124/jpet.118.24867429991481
  • YangJY, XueX, TianH, et al. Role of microglia in ethanol-induced neurodegenerative disease: pathological and behavioral dysfunction at different developmental stages. Pharmacol Ther. 2014;144(3):321–337. doi:10.1016/j.pharmthera.2014.07.00225017304
  • ZhangHR, PengJH, ChengXB, et al. Paeoniflorin attenuates amyloidogenesis and the inflammatory responses in a transgenic mouse model of alzheimer’s disease. Neurochem Res. 2015;40(8):1583–1592. doi:10.1007/s11064-015-1632-z26068144
  • Mc GuireC, BeyaertR, van LooG. Death receptor signalling in central nervous system inflammation and demyelination. Trends Neurosci. 2011;34(12):619–628. doi:10.1016/j.tins.2011.09.00221999927
  • RaaschJ, ZellerN, van LooG, et al. IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system. Brain. 2011;134(Pt 4):1184–1198. doi:10.1093/brain/awq35921310728
  • SreekumarPG, HintonDR, KannanR. Methionine sulfoxide reductase a: structure, function and role in ocular pathology. World J Biol Chem. 2011;2(8):184–192. doi:10.4331/wjbc.v2.i8.18421909460
  • WuY, XieG, XuY, et al. PEP-1-MsrA ameliorates inflammation and reduces atherosclerosis in apolipoprotein E deficient mice. J Transl Med. 2015;13:316. doi:10.1186/s12967-015-0677-826410585
  • SorceS, KrauseKH, JaquetV. Targeting NOX enzymes in the central nervous system: therapeutic opportunities. Cell Mol Life Sci. 2012;69(14):2387–2407. doi:10.1007/s00018-012-1014-522643836
  • FanB, WangBF, CheL, et al. Blockage of NOX2/MAPK/NF-kappaB pathway protects photoreceptors against glucose deprivation-induced cell death. Oxid Med Cell Longev. 2017;2017:5093473. doi:10.1155/2017/509347329085555
  • LeungEL, FanXX, WongMP, et al. Targeting tyrosine kinase inhibitor-resistant non-small cell lung cancer by inducing epidermal growth factor receptor degradation via methionine 790 oxidation. Antioxid Redox Signal. 2016;24(5):263–279. doi:10.1089/ars.2015.642026528827
  • YangCM, HsiehHL, YuPH, LinCC, LiuSW. IL-1beta induces MMP-9-dependent brain astrocytic migration via transactivation of PDGF receptor/NADPH oxidase 2-derived reactive oxygen species signals. Mol Neurobiol. 2015;52(1):303–317. doi:10.1007/s12035-014-8838-y25159478
  • FanH, WuPF, ZhangL, et al. Methionine sulfoxide reductase A negatively controls microglia-mediated neuroinflammation via inhibiting ROS/MAPKs/NF-kappaB signaling pathways through a catalytic antioxidant function. Antioxid Redox Signal. 2015;22(10):832–847. doi:10.1089/ars.2014.602225602783
  • YamazakiR, BabaH, YamaguchiY. Unconventional myosin ID is involved in remyelination after cuprizone-induced demyelination. Neurochem Res. 2018;43(1):195–204. doi:10.1007/s11064-017-2413-728986688
  • FanH, ZhaoJG, YanJQ, et al. Effect of notch1 gene on remyelination in multiple sclerosis in mouse models of acute demyelination. J Cell Biochem. 2018;119(11):9284–9294. doi:10.1002/jcb.2719730010211
  • McIntoshA, MelaV, HartyC, et al. Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in app/ps1 mice. Brain Pathol. 2019;29(5):606–621. doi:10.1111/bpa.v29.530661261
  • LiuJ, TianD, MuruganM, et al. Microglial Hv1 proton channel promotes cuprizone-induced demyelination through oxidative damage. J Neurochem. 2015;135(2):347–356. doi:10.1111/jnc.2015.135.issue-226173779
  • MeiF, WangH, LiuS, et al. Stage-specific deletion of olig2 conveys opposing functions on differentiation and maturation of oligodendrocytes. J Neurosci. 2013;33(19):8454–8462. doi:10.1523/JNEUROSCI.2453-12.201323658182
  • WegenerA, DebouxC, BachelinC, et al. Gain of olig2 function in oligodendrocyte progenitors promotes remyelination. Brain. 2015;138(Pt 1):120–135. doi:10.1093/brain/awu37525564492
  • CoprayS, BalasubramaniyanV, LevengaJ, et al. Olig2 overexpression induces the in vitro differentiation of neural stem cells into mature oligodendrocytes. Stem Cells. 2006;24(4):1001–1010. doi:10.1634/stemcells.2005-023916253982
  • GravelM, RobertF, KottisV, et al. 2ʹ,3ʹ-cyclic nucleotide 3ʹ-phosphodiesterase: a novel RNA-binding protein that inhibits protein synthesis. J Neurosci Res. 2009;87(5):1069–1079. doi:10.1002/jnr.v87:519021295
  • LeeJ, GravelM, ZhangR, et al. Process outgrowth in oligodendrocytes is mediated by cnp, a novel microtubule assembly myelin protein. J Cell Biol. 2005;170(4):661–673. doi:10.1083/jcb.20041104716103231
  • KeirsteadHS. Stem cells for the treatment of myelin loss. Trends Neurosci. 2005;28(12):677–683. doi:10.1016/j.tins.2005.09.00816213602
  • MarraliG, SalamoneP, CasaleF, et al. NADPH oxidase 2 (NOX2) enzyme activation in patients with chronic inflammatory demyelinating polyneuropathy. Eur J Neurol. 2016;23(5):958–963. doi:10.1111/ene.2016.23.issue-526924156
  • CarvalhoFB, GutierresJM, BeckmannD, et al. Quercetin treatment regulates the Na(+), K(+)-ATPase activity, peripheral cholinergic enzymes, and oxidative stress in a rat model of demyelination. Nutr Res. 2018;55:45–56. doi:10.1016/j.nutres.2018.04.00429914627
  • GabbitaSP, AksenovMY, LovellMA, MarkesberyWR. Decrease in peptide methionine sulfoxide reductase in Alzheimer’s disease brain. J Neurochem. 1999;73(4):1660–1666. doi:10.1046/j.1471-4159.1999.0731660.x10501213
  • LiuF, HindupurJ, NguyenJL, et al. Methionine sulfoxide reductase a protects dopaminergic cells from parkinson’s disease-related insults. Free Radic Biol Med. 2008;45(3):242–255. doi:10.1016/j.freeradbiomed.2008.03.02218456002
  • PalR, OienDB, ErsenFY, et al. Elevated levels of brain-pathologies associated with neurodegenerative diseases in the methionine sulfoxide reductase a knockout mouse. Exp Brain Res. 2007;180(4):765–774. doi:10.1007/s00221-007-0903-617333008
  • BhatiaHS, BaronJ, HaglS, et al. Rice bran derivatives alleviate microglia activation: possible involvement of MAPK pathway. J Neuroinflammation. 2016;13(1):148. doi:10.1186/s12974-016-0615-627301644
  • LeeJW, GordiyenkoNV, MarchettiM, et al. Gene structure, localization and role in oxidative stress of methionine sulfoxide reductase A (MSRA) in the monkey retina. Exp Eye Res. 2006;82(5):816–827. doi:10.1016/j.exer.2005.10.00316364291
  • MauryaSK, MishraR. Co-localization and interaction of Pax5 with Iba1 in brain of mice. Cell Mol Neurobiol. 2018;38(4):919–927. doi:10.1007/s10571-017-0566-129134420
  • CeramiA. Inflammatory cytokines. Clin Immunol Immunopathol. 1992;62(1 Pt 2):S3–S10. doi:10.1016/0090-1229(92)90035-M1728986
  • SchieberM, ChandelNS. ROS function in redox signaling and oxidative stress. Curr Biol. 2014;24(10):R453–R462. doi:10.1016/j.cub.2014.03.03424845678
  • WangHW, ZhangY, TanPP, et al. Mitochondrial respiratory chain dysfunction mediated by ros is a primary point of fluoride-induced damage in hepa1-6 cells. Environ Pollut. 2019;255(Pt 3):113359. doi:10.1016/j.envpol.2019.11335931614248
  • YermolaievaO, XuR, SchinstockC, et al. Methionine sulfoxide reductase a protects neuronal cells against brief hypoxia/reoxygenation. Proc Natl Acad Sci U S A. 2004;101(5):1159–1164. doi:10.1073/pnas.030821510014745014
  • McCordJM, EdeasMA. SOD, oxidative stress and human pathologies: a brief history and a future vision. Biomed Pharmacother. 2005;59(4):139–142. doi:10.1016/j.biopha.2005.03.00515862706
  • ZhengY, LiuY, GeJ, et al. Resveratrol protects human lens epithelial cells against H2O2-induced oxidative stress by increasing catalase, SOD-1, and HO-1 expression. Mol Vis. 2010;16:1467–1474.20806083
  • LiuL, RezvaniHR, BackJH, et al. Inhibition of p38 MAPK signaling augments skin tumorigenesis via NOX2 driven ROS generation. PLoS One. 2014;9(5):e97245. doi:10.1371/journal.pone.009724524824222
  • MengT, YuJ, LeiZ, et al. Propofol reduces lipopolysaccharide-induced, NADPH oxidase (NOX 2) mediated TNF- alpha and IL-6 production in macrophages. Clin Dev Immunol. 2013;2013:325481. doi:10.1155/2013/32548124371447
  • ChuW, LiM, LiF, et al. Immediate splenectomy down-regulates the MAPK-NF-kappaB signaling pathway in rat brain after severe traumatic brain injury. J Trauma Acute Care Surg. 2013;74(6):1446–1453. doi:10.1097/TA.0b013e31829246ad23694871
  • SunHN, ShenGN, JinYZ, et al. 2-cyclohexylamino-5,8-dimethoxy-1,4-naphthoquinone inhibits lps-induced bv2 microglial activation through MAPK/NF-kB signaling pathways. Heliyon. 2016;2(7):e00132. doi:10.1016/j.heliyon.2016.e0013227512726
  • GuSX, BlokhinIO, WilsonKM, et al. Protein methionine oxidation augments reperfusion injury in acute ischemic stroke. JCI Insight. 2016;1(7). doi:10.1172/jci.insight.86460