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Original Research

Chlorogenic Acid Alleviates Aβ25-35-Induced Autophagy and Cognitive Impairment via the mTOR/TFEB Signaling Pathway

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Pages 1705-1716 | Published online: 04 May 2020

References

  • HuberCM, YeeC, MayT, et al. Cognitive decline in preclinical alzheimer’s disease: amyloid-beta versus tauopathy. J Alzheimers Dis. 2018;61(1):265–281. doi:10.3233/JAD-17049029154274
  • QuerfurthHW, LaFerlaFM. Alzheimer’s disease. N Engl J Med. 2010;362(4):329–344. doi:10.1056/NEJMra090914220107219
  • SelkoeDJ, HardyJ. The amyloid hypothesis of Alzheimer‘s disease at 25 years. EMBO Mol Med. 2016;8(6):595–608. doi:10.15252/emmm.20160621027025652
  • SevignyJ, ChiaoP, BussièreT, et al. The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease. Nature. 2016;537(7618):50–56. doi:10.1038/nature1932327582220
  • MenziesFM, FlemingA, RubinszteinDC. Compromised autophagy and neurodegenerative diseases. Nat Rev Neurosci. 2015;16(6):345–357. doi:10.1038/nrn396125991442
  • LuoR, SuLY, LiG, et al. Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model. Autophagy. 2019;16;1–18.31516068
  • WaniA, GuptaM, AhmadM, et al. Alborixin clears amyloid-β by inducing autophagy through PTEN-mediated inhibition of the AKT pathway. Autophagy. 2019;15;1–19.30354937
  • SettembreC, Di MaltaC, PolitoVA, et al. TFEB links autophagy to lysosomal biogenesis. Science. 2011;332(6036):1429–1433. doi:10.1126/science.120459221617040
  • YamamotoF, TaniguchiK, MamadaN, et al. TFEB-mediated enhancement of the autophagy-lysosomal pathway dually modulates the process of amyloid β-protein generation in neurons. Neuroscience. 2019;402:11–22. doi:10.1016/j.neuroscience.2019.01.01030677488
  • SettembreC, FraldiA, MedinaDL, et al. Signals from the lysosome: a control centre for cellular clearance and energy metabolism. Nat Rev Mol Cell Biol. 2013;14(5):283–296. doi:10.1038/nrm356523609508
  • SongHL, DemirevAV, KimNY, et al. Ouabain activates transcription factor EB and exerts neuroprotection in models of alzheimer’s disease. Mol Cell Neurosci. 2019;95:13–24. doi:10.1016/j.mcn.2018.12.00730594669
  • CortesCJ, La SpadaAR. TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: molecular mechanisms, cellular processes, and emerging therapeutic opportunities. Neurobiol Dis. 2019;122:83–93. doi:10.1016/j.nbd.2018.05.01229852219
  • NaveedM, HejaziV, AbbasM, et al. Chlorogenic acid (CGA): a pharmacological review and call for further research. Biomed Pharmacother. 2018;97:67–74. doi:10.1016/j.biopha.2017.10.06429080460
  • SongJ, ZhouN, MaW, et al. Modulation of gut microbiota by chlorogenic acid pretreatment on rats with adrenocorticotropic hormone induced depression-like behavior. Food Funct. 2019;10(5):2947–2957. doi:10.1039/c8fo02599a31073553
  • RebaiO, AmriM. Chlorogenic acid prevents AMPA-mediated excitotoxicity in optic nerve oligodendrocytes through a PKC and caspase-dependent pathways. Neurotox Res. 2018;34(3):559–573. doi:10.1007/s12640-018-9911-530006682
  • FangSQ, WangYT, WeiJX, et al. Beneficial effects of chlorogenic acid on alcohol-induced damage in PC12 cells. Biomed Pharmacother. 2016;79:254–262. doi:10.1016/j.biopha.2016.02.01827044836
  • IshidaK, YamamotoM, MisawaK, et al. Coffee polyphenols prevent cognitive dysfunction and suppress amyloid β plaques in APP/PS2 transgenic mouse. Neurosci Res. 2019;pii: S0168-0102(18)30575–3.
  • DomitrovićR, CvijanovićO, ŠušnićV, et al. Renoprotective mechanisms of chlorogenic acid in cisplatin-induced kidney injury. Toxicology. 2014;324:98–107. doi:10.1016/j.tox.2014.07.00425043994
  • YanH, GaoYQ, ZhangY, et al. Chlorogenic acid alleviates autophagy and insulin resistance by suppressing JNK pathway in a rat model of nonalcoholic fatty liver disease. J Biosci. 2018;43(2):287–294. doi:10.1007/s12038-018-9746-529872017
  • WengJ, WengJ, RenL, et al. Interactions between gold nanoparticles and amyloidβ 25-35 peptide. Nanobiotechnol Iet. 2014;8(4):295–303. doi:10.1049/iet-nbt.2013.0071
  • OhkawaraT, TakedaH, NishihiraJ.Protective effect of chlorogenic acid on the inflammatory damage of pancreas and lung in mice with, l -arginine-induced pancreatitis[J]. Life Sci.2017;190:91–96. doi:10.1016/j.lfs.2017.09.01528919396
  • FuW, DaiY, MaT, et al. Tongluo Xingnao effervescent tablet reverses memory deficit and reduces plaque load in APPswe/PS1dE9 mice. Exp Ther Med. 2018;15(4):4005–4013. doi:10.3892/etm.2018.589729563991
  • ZhuJ, ChenX, SongY, et al. Deficit of RACK1 contribute to the spatial memory impairment via up regulating BECLIN1 to induce autophagy. Life Sci. 2016;151:115–121. doi:10.1016/j.lfs.2016.02.01426930371
  • JabirNR, KhanFR, TabrezS. Cholinesterase targeting by polyphenols: a therapeutic approach for the treatment of Alzheimer’s disease. CNS Neurosci Ther. 2018;24(9):753–762. doi:10.1111/cns.1297129770579
  • NuzzoD, PrestiG, PiconeP, et al. Effects of the Aphanizomenon flos-aquae Extract (Klamin®) on a neurodegeneration cellular Model. Oxid Med Cell Longev. 2018;2018:1–14. doi:10.1155/2018/9089016
  • NuzzoD, AmatoA, PiconeP, et al. A natural dietary supplement with a combination of nutrients prevents neurodegeneration induced by a high fat diet in mice.[J]. Nutrients. 2018;10(9):1130. doi:10.3390/nu10091130
  • ItoH, SunXL, WatanabeM, et al. Chlorogenic acid and its metabolite m-coumaric acid evoke neurite outgrowth in hippocampal neuronal cells. Biosci Biotechnol Biochem. 2008;72(3):885–888. doi:10.1271/bbb.7067018323641
  • MiyamaeY, KurisuM, MurakamiK, et al. Protective effects of caffeoylquinic acids on the aggregation and neurotoxicity of the 42-residue amyloid β-protein. Bioorg Med Chem. 2012;20(19):5844–5849. doi:10.1016/j.bmc.2012.08.00122921742
  • BlankenAE, HurtzS, ZarowC, et al. Associations between hippocampal morphometry and neuropathologic markers of Alzheimer’s disease using 7 T MRI. Neuroimage Clin. 2017;15:56–61. doi:10.1016/j.nicl.2017.04.02028491492
  • OrrME, OddoS. Autophagic/lysosomal dysfunction in Alzheimer’s disease. Alzheimers Res Ther. 2013;5(5):53. doi:10.1186/alzrt21724171818
  • TungYT, WangBJ, HuMK, et al. Autophagy: a double-edged sword in Alzheimer’s disease. J Biosci. 2012;37(1):157–165. doi:10.1007/s12038-011-9176-022357213
  • LaplanteM, SabatiniDM. mTOR signaling in growth control and disease. Cell. 2012;149(2):274–293. doi:10.1016/j.cell.2012.03.01722500797
  • SancakY, Bar-PeledL, ZoncuR, et al. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010;141(2):290–303. doi:10.1016/j.cell.2010.02.02420381137
  • NezichCL, WangC, FogelAI, et al. MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5[J]. J Cell Biol. 2015;210(3):435–450. doi:10.1083/jcb.20150100226240184
  • Martini-StoicaH, XuY, BallabioA, et al. The autophagy–lysosomal pathway in neurodegeneration: a TFEB perspective[J]. Trends Neurosci. 2016;39:221–234.26968346
  • BradyOA, Martina, JoséA, PuertollanoR. Emerging roles for TFEB in the immune response and inflammation[J]. Autophagy. 2017;14;1–9.28980869
  • WangL, JinG, yuH, et al. Protective effect of Tenuifolin against Alzheimer’s disease. [J]. Neurosci Lett. 2019;705:195–201.31039426
  • DengH, ZhengM, HuZ, ZengX, KuangN, FuY. Effects of daphnetin on the autophagy signaling pathway of fibroblast-like synoviocytes in rats with collagen-induced arthritis (CIA) induced by TNF-alpha. Cytokine. 2019;127:154952. doi:10.1016/j.cyto.2019.15495231865066
  • ZachariM1, GanleyIG2. The mammalian ULK1 complex and autophagy initiation[J]. Essays Biochem. 2017;61(6):585–596. doi:10.1042/EBC2017002129233870
  • YeX, Xu-JieZ, ZhangH. immunology, EXPLORING THE ROLE OF AUTOPHAGY-RELATED GEne 5(ATG5) yields important insights into autophagy in autoimmune/autoinflammatory diseases. Front Immunol. 2018;9:2334. doi:10.3389/fimmu.2018.0233430386331
  • ErbilS, OralO, MitouG, et al. RACK1 is an interaction partner of ATG5 and a novel regulator of autophagy[J]. J Biol Chem. 2016;291(32):16753–16765. doi:10.1074/jbc.M115.70808127325703