Protective Effects of Rocuronium Bromide on Ischemia-Reperfusion Injury in Skeletal Muscle Induced by Tourniquet in Patients Undergoing Elective Unilateral Total Knee Arthroplasty: A Prospective, Double Blind, Randomized, Controlled Study

References

• WangK, NiS, LiZ, et al. The effects of tourniquet use in total knee arthroplasty: a randomized, controlled trial. Knee Surg Sports Traumatol Arthrosc. 2017;25(9):2849–2857. doi:10.1007/s00167-015-3964-226745962
   PubMed Web of Science ®Google Scholar
• DennisDA, KittelsonAJ, YangCC, MinerTM, KimRH, Stevens-LapsleyJE. Does tourniquet use in TKA affect recovery of lower extremity strength and function? A randomized trial. Clin Orthop Relat Res. 2016;474(1):69–77. doi:10.1007/s11999-015-4393-826100254
   PubMed Web of Science ®Google Scholar
• ParadisS, CharlesAL, MeyerA, et al. Chronology of mitochondrial and cellular events during skeletal muscle ischemia-reperfusion. Am J Physiol Cell Physiol. 2016;310(11):C968–982. doi:10.1152/ajpcell.00356.201527076618
   PubMed Web of Science ®Google Scholar
• OhlendieckK, ErvastiJM, SnookJB, CampbellKP. Dystrophin-glycoprotein complex is highly enriched in isolated skeletal muscle sarcolemma. J Cell Biol. 1991;112(1):135–148. doi:10.1083/jcb.112.1.1351986002
   PubMed Web of Science ®Google Scholar
• KidoM, OtaniH, KyoiS, et al. Ischemic preconditioning-mediated restoration of membrane dystrophin during reperfusion correlates with protection against contraction-induced myocardial injury. Am J Physiol Heart Circ Physiol. 2004;287(1):H81–90. doi:10.1152/ajpheart.01140.200315001448
   PubMed Web of Science ®Google Scholar
• CamposEC, RomanoMM, PradoCM, RossiMA. Isoproterenol induces primary loss of dystrophin in rat hearts: correlation with myocardial injury. Int J Exp Pathol. 2008;89(5):367–381. doi:10.1111/j.1365-2613.2008.00604.x18808529
   PubMed Web of Science ®Google Scholar
• JiangL, LiL, ShenJ, QiZ, GuoL. Effect of dexmedetomidine on lung ischemiareperfusion injury. Mol Med Rep. 2014;9(2):419–426. doi:10.3892/mmr.2013.186724345905
   PubMed Web of Science ®Google Scholar
• LeurcharusmeeP, SawaddirukP, PunjasawadwongY, ChattipakornN, ChattipakornSC. The possible pathophysiological outcomes and mechanisms of tourniquet-induced ischemia-reperfusion injury during total knee arthroplasty. Oxid Med Cell Longev. 2018;2018:8087598. doi:10.1155/2018/808759830524661
   PubMed Web of Science ®Google Scholar
• Garcia-de-la-AsuncionJ, Perez-SolazA, CarrauM, BeldaFJ, Perez-GrieraJ, GarrigesB. Different oxidative stress marker levels in blood from the operated knee or the antecubital vein in patients undergoing knee surgery: a tourniquet-induced ischemia-reperfusion model. Redox Rep. 2012;17(5):194–199. doi:10.1179/1351000212Y.000000002222889454
   PubMed Web of Science ®Google Scholar
• CsonkaC, PaliT, BencsikP, GorbeA, FerdinandyP, CsontT. Measurement of NO in biological samples. Br J Pharmacol. 2015;172(6):1620–1632. doi:10.1111/bph.1283224990201
   PubMed Web of Science ®Google Scholar
• TsuiJC, BakerDM, ShawSG, DashwoodMR. Alterations in nitric oxide synthase isoforms in acute lower limb ischemia and reperfusion. Angiology. 2007;58(5):586–592. doi:10.1177/000331970730546618024942
   PubMed Web of Science ®Google Scholar
• JawharA, PoneliesN, SchildL. Effect of limited ischemia time on the amount and function of mitochondria within human skeletal muscle cells. Eur J Trauma Emerg Surg. 2016;42(6):767–773. doi:10.1007/s00068-015-0600-226608839
   PubMed Web of Science ®Google Scholar
• KimTK, BamneAB, SimJA, ParkJH, NaYG. Is lower tourniquet pressure during total knee arthroplasty effective? A prospective randomized controlled trial. BMC Musculoskelet Disord. 2019;20(1):275. doi:10.1186/s12891-019-2636-731159799
   PubMed Web of Science ®Google Scholar
• HarstenA, BandholmT, KehletH, Toksvig-LarsenS. Tourniquet versus no tourniquet on knee-extension strength early after fast-track total knee arthroplasty; a randomized controlled trial. Knee. 2015;22(2):126–130. doi:10.1016/j.knee.2014.12.01025648580
   PubMed Web of Science ®Google Scholar
• HalladinNL, ZahleFV, RosenbergJ, GogenurI. Interventions to reduce tourniquet-related ischaemic damage in orthopaedic surgery: a qualitative systematic review of randomised trials. Anaesthesia. 2014;69(9):1033–1050. doi:10.1111/anae.1266424800642
   PubMed Web of Science ®Google Scholar
• DongX, XingQ, LiY, HanX, SunL. Dexmedetomidine protects against ischemia-reperfusion injury in rat skeletal muscle. J Surg Res. 2014;186(1):240–245. doi:10.1016/j.jss.2013.07.05224007817
   PubMed Web of Science ®Google Scholar
• OzkanD, AkkayaT, YalcindagA, et al. Propofol sedation in total knee replacement: effects on oxidative stress and ischemia-reperfusion damage. Anaesthesist. 2013;62(7):537–542. doi:10.1007/s00101-013-2192-823812272
   PubMed Web of Science ®Google Scholar
• KosucuM, CoskunI, ErogluA, et al. The effects of spinal, inhalation, and total intravenous anesthetic techniques on ischemia-reperfusion injury in arthroscopic knee surgery. Biomed Res Int. 2014;2014:846570. doi:10.1155/2014/84657024701585
   PubMed Web of Science ®Google Scholar
• LedowskiT, NisslerS, WenkM, Pogatzki-ZahnEM, SegelckeD. Effects of muscle relaxants on ischaemia damage in skeletal muscle. Sci Rep. 2018;8(1):5794. doi:10.1038/s41598-018-24127-229643396
   PubMed Web of Science ®Google Scholar
• SchepensT, CammuG. Neuromuscular blockade: what was, is and will be. Acta Anaesthesiol Belg. 2014;65(4):151–159.25622380
   PubMedGoogle Scholar
• VernonDD, WitteMK. Effect of neuromuscular blockade on oxygen consumption and energy expenditure in sedated, mechanically ventilated children. Crit Care Med. 2000;28(5):1569–1571. doi:10.1097/00003246-200005000-0005110834713
   PubMed Web of Science ®Google Scholar
• MatrePR, MuX, WuJ, et al. CRISPR/Cas9-based dystrophin restoration reveals a novel role for dystrophin in bioenergetics and stress resistance of muscle progenitors. Stem Cells. 2019;37(12):1615–1628. doi:10.1002/stem.309431574188
   PubMed Web of Science ®Google Scholar
• AllenDG, WhiteheadNP, FroehnerSC. Absence of dystrophin disrupts skeletal muscle signaling: roles of Ca2+, reactive oxygen species, and nitric oxide in the development of muscular dystrophy. Physiol Rev. 2016;96(1):253–305. doi:10.1152/physrev.00007.201526676145
   PubMed Web of Science ®Google Scholar
• JeongJS, SuhJK, ChoES, KimDW, JeongMA. Antioxidant effect of muscle relaxants (vecuronium, rocuronium) on the rabbit abdominal aortic endothelial damage induced by reactive oxygen species. Korean J Anesthesiol. 2013;65(6):552–558. doi:10.4097/kjae.2013.65.6.55224427462
   PubMedGoogle Scholar
• JonesSP, GirodWG, HuangPL, LeferDJ. Myocardial reperfusion injury in neuronal nitric oxide synthase deficient mice. Coron Artery Dis. 2000;11(8):593–597. doi:10.1097/00019501-200012000-0000411107506
   PubMed Web of Science ®Google Scholar
• JandaM, BajoratJ, KudlikC, et al. Comparison of heart rate variability response in children undergoing elective endotracheal intubation with and without neuromuscular blockade: a randomized controlled trial. Paediatr Anaesth. 2013;23(12):1153–1159. doi:10.1111/pan.1223623910069
   PubMed Web of Science ®Google Scholar
• JuddDL, EckhoffDG, Stevens-LapsleyJE. Muscle strength loss in the lower limb after total knee arthroplasty. Am J Phys Med Rehabil. 2012;91(3):220–226. doi:10.1097/PHM.0b013e3182411e4922257971
   PubMed Web of Science ®Google Scholar
• BaekSB, ShinMS, HanJH, et al. Rocuronium bromide inhibits inflammation and pain by suppressing nitric oxide production and enhancing prostaglandin E2 synthesis in endothelial cells. Int Neurourol J. 2016;20(4):296–303. doi:10.5213/inj.1632796.39828043117
   PubMed Web of Science ®Google Scholar
• ZhangY, LiD, LiuP, WangX, LiM. Effects of different methods of using pneumatic tourniquet in patients undergoing total knee arthroplasty: a randomized control trial. Ir J Med Sci. 2017;186(4):953–959. doi:10.1007/s11845-017-1585-028260153
   PubMed Web of Science ®Google Scholar