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Original Research

Intermedin Alleviates Renal Ischemia-Reperfusion Injury and Enhances Neovascularization in Wistar Rats

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Pages 4825-4834 | Published online: 10 Nov 2020

References

  • HosteEA, SchurgersM. Epidemiology of acute kidney injury. Contrib Nephrol. 2010;165:1–8.20427949
  • BonventreJV, YangL. Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest. 2011;121(11):21–4210. doi:10.1172/JCI45161
  • MehtaRL, PascualMT, SorokoS, et al. Spectrum of acute renal failure in the intensive care unit: the PICARD experience. Kidney Int. 2004;66(4):1613–1621. doi:10.1111/j.1523-1755.2004.00927.x15458458
  • WhiteLE, HassounHT. Inflammatory mechanisms of organ crosstalk during ischemic acute kidney injury. Int J Nephrol. 2011;2012:505197.21826270
  • RohJ, ChangCL, BhallaA, KleinC, HsuSY. Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes. J Bio Chem. 2004;279(8):7264–7274.14615490
  • TakeiY, HyodoS, KatafuchiT, MinaminoN. Novel fish-derived adrenomedullin in mammals: structure and possible function. Peptides. 2004;25(10):1643–1656. doi:10.1016/j.peptides.2004.06.02615476931
  • BosmanFT, StamenkovicI. Functional structure and composition of the extracellular matrix. J Pathol. 2003;200(4):8–423. doi:10.1002/path.1437
  • DejonckheereE, VandenbrouckeRE, LibertC. Matrix metalloproteinases as drug targets in ischemia/reperfusion injury. Drug Discov Today. 2011;16(17):78–762.
  • CavdarZ, OzbalS, CelikA, et al. The effects of alpha-lipoic acid on MMP-2 and MMP-9 activities in a rat renal ischemia and re-perfusion model. Biotech Histochem. 2014;89(4):304–314.24160412
  • KunugiS, ShimizuA, KuwaharaN, et al. Inhibition of matrix metalloproteinases reduces ischemia-reperfusion acute kidney injury. Lab Invest. 2011;91(2):80–170. doi:10.1038/labinvest.2010.174
  • KanekoT, ShimizuA, MiiA, et al. Role of matrix metalloproteinase-2 in recovery after tubular damage in acute kidney injury in mice. S Karger AG. 2012;122(1):23–35.
  • YanagisawaM, KuriharaH, KimuraS, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332(6163):411–415. doi:10.1038/332411a02451132
  • ArfianN, EmotoN, Vignon-ZellwegerN, NakayamaK, YagiK, HirataK-I. ET-1 deletion from endothelial cells protects the kidney during the extension phase of ischemia/reperfusion injury. Biochem Biophys Res Commun. 2012;425(2):443–449. doi:10.1016/j.bbrc.2012.07.12122846580
  • QiaoX, LiRS, LiH, et al. Intermedin protects against renal ischemia-reperfusion injury by inhibition of oxidative stress. Am J Physiol. 2013;304(1):F112–F119.
  • WangY, TianJ, QiaoX, et al. Intermedin protects against renal ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress. BioMed Central. 2015;16(1):169.
  • SheashaaH, LotfyA, ElhusseiniF, et al. Protective effect of adipose-derived mesenchymal stem cells against acute kidney injury induced by ischemia-reperfusion in Sprague-Dawley rats. Exp Ther Med. 2016;11(5):1573–1580.27168775
  • TianJ, WangY, ZhouX, et al. Rapamycin slows IgA nephropathy progression in the rat. Am J Nephrol. 2014;39(3):29–218. doi:10.1159/000358844
  • SaitoK, MatsuoY, ImafujiH, et al. Xanthohumol inhibits angiogenesis by suppressing nuclear factor-κB activation in pancreatic cancer. Cancer Sci. 2018;109(1):132–140. doi:10.1111/cas.1344129121426
  • HolmesD, CampbellM, HarbinsonM, BellD. Protective effects of intermedin on cardiovascular, pulmonary and renal diseases: comparison with adrenomedullin and CGRP. Curr Protein Pept Sci. 2013;14(4):294–329. doi:10.2174/1389203711314999004923745696
  • WangY, LiR, QiaoX, et al. Intermedin/adrenomedullin 2 protects against tubular cell hypoxia‐reoxygenation injury in vitro by promoting cell proliferation and upregulating cyclin D 1 expression. Nephrology. 2013;18(9):623–632. doi:10.1111/nep.1211423782291
  • BasileD-P. The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function. Kidney Int. 2007;72(2):151–156. doi:10.1038/sj.ki.500231217495858
  • PearsonLJ, YandleTG, NichollsMG, EvansJJ. Intermedin (adrenomedullin-2): a potential protective role in human aortic endothelial cells. Cell Physiol Biochem. 2009;23(1):97–108. doi:10.1159/00020409819255504
  • SmithRS Jr, GaoL, BledsoeG, ChaoL, ChaoJ. Intermedin is a new angiogenic growth factor. Am J Physiol Heart Circ Physiol. 2009;297(3):0–7. doi:10.1152/ajpheart.00404.2009
  • TakeiY, InoueK, OgoshiM, KawaharaT, BannaiH, MiyanoS. Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator. FEBS Lett. 2004;556(1):53–58. doi:10.1016/S0014-5793(03)01368-114706825
  • Kaelin-WilliamG. The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat Rev Cancer. 2008;8(11):73–865.
  • CaiY, XuMJ, TengX, et al. Intermedin inhibits vascular calcification by increasing the level of matrix gamma-carboxyglutamic acid protein. Cardiovasc Res. 2009;85(4):73–864.
  • PalletN, ThervetE, TimsitM-O. Angiogenic response following renal ischemia reperfusion injury: new players. Prog Urol. 2014;24:S20–S25. doi:10.1016/S1166-7087(14)70059-424950928
  • EltzschigHK, EckleT. Ischemia and reperfusion–from mechanism to translation. Nat Med. 2011;17(11):401–1391. doi:10.1038/nm.250721475220
  • BasileDP, FredrichK, WeihrauchD, HattanN, ChilianWM. Angiostatin and matrix metalloprotease expression following ischemic acute renal failure. Am J Physiol Renal Physiol. 2004;286(5):0–902. doi:10.1152/ajprenal.00328.2003
  • BasileDP, FredrichK, ChelladuraiB, LeonardEC, ParrishAR. Renal ischemia reperfusion inhibits VEGF expression and induces ADAMTS-1, a novel VEGF inhibitor. Am J Physiol Renal Physiol. 2008;294(4):0–36. doi:10.1152/ajprenal.00596.2007
  • NagaseH, VisseR, MurphyG. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res. 2006;69(3):562–573. doi:10.1016/j.cardiores.2005.12.00216405877
  • SuttonT-A. Minocycline reduces renal microvascular leakage in a rat model of ischemic renal injury. Am J Physiol Renal Physiol. 2004;288(1).
  • FirthJD, RaineAEG, RatcliffePJ, LedinghamJGG. Endothelin: an important factor in acute renal failure? Lancet. 1988;332(8621):1179–1182.
  • MaczewskiM, BeresewiczA. The role of endothelin, protein Kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig hearts. J Mol Cell Cardiol. 2000;32(2):297–310. doi:10.1006/jmcc.1999.107310722805
  • ZouX, GuD, XingX, et al. Human mesenchymal stromal cell-derived extracellular vesicles alleviate renal ischemic reperfusion injury and enhance angiogenesis in rats. Am J Transl Res. 2016;8(10):4289–4299.27830012