Dual Targeting of Cell Growth and Phagocytosis by Erianin for Human Colorectal Cancer

References

• BermudezM, Aguilar-MedinaM, Lizarraga-VerdugoE, et al. LncRNAs as regulators of autophagy and drug resistance in colorectal cancer. Front Oncol. 2019;9:1008. doi:10.3389/fonc.2019.0100831632922
   PubMed Web of Science ®Google Scholar
• FearonER. Molecular genetics of colorectal cancer. Annu Rev Pathol. 2011;6:479–507. doi:10.1146/annurev-pathol-011110-13023521090969
   PubMed Web of Science ®Google Scholar
• StrumWB. Colorectal Adenomas. N Engl J Med. 2016;375:389–390. doi:10.1056/NEJMc1604867
   PubMedGoogle Scholar
• ThrumurthySG, ThrumurthySS, GilbertCE, RossP, HajiA. Colorectal adenocarcinoma: risks, prevention and diagnosis. BMJ. 2016;354:i3590. doi:10.1136/bmj.i359027418368
   PubMed Web of Science ®Google Scholar
• NordlingerB, SorbyeH, GlimeliusB, et al.;Group EG-ITC, Cancer Research UK, Arbeitsgruppe Lebermetastasen und-tumoren in der Chirurgischen Arbeitsgemeinschaft O, Australasian Gastro-Intestinal Trials G and Federation Francophone de Cancerologie D. Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial. Lancet. 2008;371:1007–1016. doi:10.1016/S0140-6736(08)60455-918358928
   PubMed Web of Science ®Google Scholar
• LongleyDB, HarkinDP, JohnstonPG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003;3:330–338. doi:10.1038/nrc107412724731
   PubMed Web of Science ®Google Scholar
• MeyerhardtJA, MayerRJ. Systemic therapy for colorectal cancer. N Engl J Med. 2005;352:476–487. doi:10.1056/NEJMra04095815689586
   PubMed Web of Science ®Google Scholar
• LukJM, WangX, LiuP, et al. Traditional Chinese herbal medicines for treatment of liver fibrosis and cancer: from laboratory discovery to clinical evaluation. Liver Int. 2007;27:879–890. doi:10.1111/j.1478-3231.2007.01527.x17696925
   PubMed Web of Science ®Google Scholar
• Teixeira da SilvaJA, NgTB. The medicinal and pharmaceutical importance of dendrobium species. Appl Microbiol Biotechnol. 2017;101:2227–2239. doi:10.1007/s00253-017-8169-928197691
   PubMed Web of Science ®Google Scholar
• LiYM, WangHY, LiuGQ. Erianin induces apoptosis in human leukemia HL-60 cells. Acta Pharmacol Sin. 2001;22:1018–1022.11749794
   PubMed Web of Science ®Google Scholar
• GongYQ, FanY, WuDZ, YangH, HuZB, WangZT. In vivo and in vitro evaluation of erianin, a novel anti-angiogenic agent. Eur J Cancer. 2004;40:1554–1565. doi:10.1016/j.ejca.2004.01.04115196540
   PubMed Web of Science ®Google Scholar
• WangH, ZhangT, SunW, et al. Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo. Cell Death Dis. 2016;7:e2247. doi:10.1038/cddis.2016.13827253411
   PubMed Web of Science ®Google Scholar
• ZhuQ, ShengY, LiW, et al. Erianin, a novel dibenzyl compound in Dendrobium extract, inhibits bladder cancer cell growth via the mitochondrial apoptosis and JNK pathways. Toxicol Appl Pharmacol. 2019;371:41–54. doi:10.1016/j.taap.2019.03.02730946863
   PubMed Web of Science ®Google Scholar
• SunJ, FuX, WangY, et al. Erianin inhibits the proliferation of T47D cells by inhibiting cell cycles, inducing apoptosis and suppressing migration. Am J Transl Res. 2016;8:3077–3086.27508028
   PubMed Web of Science ®Google Scholar
• SuC, ZhangP, LiuJ, CaoY. Erianin inhibits indoleamine 2, 3-dioxygenase -induced tumor angiogenesis. Biomed Pharmacother. 2017;88:521–528. doi:10.1016/j.biopha.2017.01.09028129624
   PubMed Web of Science ®Google Scholar
• ZhangX, WangY, LiX, YangA, LiZ, WangD. The anti-carcinogenesis properties of erianin in the modulation of oxidative stress-mediated apoptosis and immune response in liver cancer. Aging (Albany NY). 2019;11:10284–10300. doi:10.18632/aging.10245631754081
   PubMedGoogle Scholar
• GowdaP, PatrickS, SinghA, SheikhT, SenE. Mutant isocitrate dehydrogenase 1 disrupts PKM2-beta-catenin-BRG1 transcriptional network-driven CD47 expression. Mol Cell Biol. 2018;38. doi:10.1128/MCB.00001-18
   PubMed Web of Science ®Google Scholar
• ChibaudelB, TournigandC, AndreT, de GramontA. Therapeutic strategy in unresectable metastatic colorectal cancer. Ther Adv Med Oncol. 2012;4:75–89. doi:10.1177/175883401143159222423266
   PubMed Web of Science ®Google Scholar
• GustavssonB, CarlssonG, MachoverD, et al. A review of the evolution of systemic chemotherapy in the management of colorectal cancer. Clin Colorectal Cancer. 2015;14:1–10. doi:10.1016/j.clcc.2014.11.00225579803
   PubMed Web of Science ®Google Scholar
• LiuZ, YuM, FeiB, SunJ, WangD. Identification of natural compound derivative for inhibition of XLF and overcoming chemoresistance in colorectal cancer cells. Drug Des Devel Ther. 2019;13:3823–3834. doi:10.2147/DDDT.S215967
   PubMed Web of Science ®Google Scholar
• ZhangN, YinY, XuSJ, ChenWS. 5-Fluorouracil: mechanisms of resistance and reversal strategies. Molecules. 2008;13:1551–1569. doi:10.3390/molecules1308155118794772
   PubMed Web of Science ®Google Scholar
• TemrazS, MukherjiD, AlameddineR, ShamseddineA. Methods of overcoming treatment resistance in colorectal cancer. Crit Rev Oncol Hematol. 2014;89:217–230. doi:10.1016/j.critrevonc.2013.08.01524075059
   PubMed Web of Science ®Google Scholar
• KudumelaRG, McGawLJ, MasokoP. Antibacterial interactions, anti-inflammatory and cytotoxic effects of four medicinal plant species. BMC Complement Altern Med. 2018;18:199. doi:10.1186/s12906-018-2264-z29970064
   PubMed Web of Science ®Google Scholar
• BaekJM, KimJY, AhnSJ, et al. Dendrobium moniliforme exerts inhibitory effects on both receptor activator of nuclear factor kappa-B ligand-mediated osteoclast differentiation in vitro and lipopolysaccharide-induced bone erosion in vivo. Molecules. 2016;21:295. doi:10.3390/molecules2103029526938522
   PubMed Web of Science ®Google Scholar
• NgTB, LiuF, WangZT. Antioxidative activity of natural products from plants. Life Sci. 2000;66:709–723. doi:10.1016/S0024-3205(99)00642-610680579
   PubMed Web of Science ®Google Scholar
• KoveitypourZ, PanahiF, VakilianM, et al. Signaling pathways involved in colorectal cancer progression. Cell Biosci. 2019;9:97. doi:10.1186/s13578-019-0361-431827763
   PubMed Web of Science ®Google Scholar
• SchatoffEM, LeachBI, DowLE. Wnt signaling and colorectal cancer. Curr Colorectal Cancer Rep. 2017;13:101–110. doi:10.1007/s11888-017-0354-928413363
   PubMed Web of Science ®Google Scholar
• BasuS, HaaseG, Ben-Ze’evA. Wnt signaling in cancer stem cells and colon cancer metastasis. F1000Res. 2016;5:699. doi:10.12688/f1000research.7579.1
   Google Scholar
• ChengX, XuX, ChenD, ZhaoF, WangW. Therapeutic potential of targeting the Wnt/beta-catenin signaling pathway in colorectal cancer. Biomed Pharmacother. 2019;110:473–481. doi:10.1016/j.biopha.2018.11.08230530050
   PubMed Web of Science ®Google Scholar
• LiQ, LaiQ, HeC, et al. RUNX1 promotes tumour metastasis by activating the Wnt/beta-catenin signalling pathway and EMT in colorectal cancer. J Exp Clin Cancer Res. 2019;38:334. doi:10.1186/s13046-019-1330-931370857
   PubMed Web of Science ®Google Scholar
• WillinghamSB, VolkmerJP, GentlesAJ, et al. The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A. 2012;109:6662–6667. doi:10.1073/pnas.112162310922451913
   PubMed Web of Science ®Google Scholar
• TsengD, VolkmerJP, WillinghamSB, et al. Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response. Proc Natl Acad Sci U S A. 2013;110:11103–11108. doi:10.1073/pnas.130556911023690610
   PubMed Web of Science ®Google Scholar
• ChenJ, ZhongMC, GuoH, et al. SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin. Nature. 2017;544:493–497. doi:10.1038/nature2207628424516
   PubMed Web of Science ®Google Scholar
• ZhangY, SimeW, JuhasM, SjolanderA. Crosstalk between colon cancer cells and macrophages via inflammatory mediators and CD47 promotes tumour cell migration. Eur J Cancer. 2013;49:3320–3334. doi:10.1016/j.ejca.2013.06.00523810249
   PubMed Web of Science ®Google Scholar
• SteinertG, ScholchS, NiemietzT, et al. Immune escape and survival mechanisms in circulating tumor cells of colorectal cancer. Cancer Res. 2014;74:1694–1704. doi:10.1158/0008-5472.CAN-13-188524599131
   PubMed Web of Science ®Google Scholar
• CaseySC, TongL, LiY, et al. MYC regulates the antitumor immune response through CD47 and PD-L1. Science. 2016;352:227–231. doi:10.1126/science.aac993526966191
   PubMed Web of Science ®Google Scholar