205
Views
20
CrossRef citations to date
0
Altmetric
Hypothesis

A Single Large Dose of Vitamin D Could be Used as a Means of Coronavirus Disease 2019 Prevention and Treatment

ORCID Icon, ORCID Icon & ORCID Icon
Pages 3429-3434 | Published online: 21 Aug 2020

References

  • AlhazzaniW, MøllerMH, ArabiYM, et al. Surviving sepsis campaign: guidelines on the management of critically Ill adults with Coronavirus disease 2019 (COVID-19). Crit Care Med. 2020;48(6):e440–e469. doi:10.1097/CCM.000000000000436332224769
  • ZhangR, LiB, GaoX. Serum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies. Am J Clin Nutr. 2017;105(4):810–819. doi:10.3945/ajcn.116.14039228251933
  • KeumN, GiovannucciE. Vitamin D supplements and cancer incidence and mortality: a meta-analysis. Br J Cancer. 2014;111(5):976–980. doi:10.1038/bjc.2014.29424918818
  • MartineauAR, JolliffeDA, HooperRL. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. doi:10.1136/bmj.i658328202713
  • ZisiD, ChallaA, MakisA. The association between vitamin D status and infectious diseases of the respiratory system in infancy and childhood. Hormones (Athens). 2019;18(4):353–363. doi:10.1007/s42000-019-00155-z31768940
  • MartineauAR, CatesCJ, UrashimaM. Vitamin D for the management of asthma. Cochrane Database Syst Rev. 2016;9(9):CD011511.27595415
  • ChawesBL, BønnelykkeK, StokholmJ. Effect of vitamin D3 supplementation during pregnancy on risk of persistent wheeze in the offspring: a randomized clinical trial. JAMA. 2016;315(4):353–361. doi:10.1001/jama.2015.1831826813208
  • BivonaG, GambinoCM, IacolinoG, et al. Vitamin D and the nervous system. Neurol Res. 2019;41(9):827–835. doi:10.1080/01616412.2019.162287231142227
  • BergqvistC, EzzedineK. Vitamin D and the skin: what should a dermatologist know? G Ital Dermatol Venereol. 2019;154(6):669–680. doi:10.23736/S0392-0488.19.06433-231302984
  • SacerdoteA, DaveP, LokshinV, et al. Type 2 diabetes mellitus, insulin resistance, and vitamin D. Curr Diab Rep. 2019;19(10):101. doi:10.1007/s11892-019-1201-y31506836
  • MurdacaG, TonacciA, NegriniS, et al. Emerging role of vitamin D in autoimmune diseases: an update on evidence and therapeutic implications. Autoimmun Rev. 2019;18(9):102350. doi:10.1016/j.autrev.2019.10235031323357
  • MichaelFH, NeilCB, HeikeAB, et al. Endocrine Society. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96(7):1911–1930. doi:10.1210/jc.2011-038521646368
  • ZhangH, HuangQ, ZhangZ, et al. Vitamin D status of postmenopausal women in winter in Shanghai. Chin J Osteoporosis. 2011;17(1):43–46. (in Chinese).
  • PeiY, LiuY, LuY, et al. The relationship between the nutritional status of vitamin D and bone turnover in males in a community of Beijing. Chin J Osteoporosis Bone Miner Res. 2013;6(4):308–313. (in Chinese).
  • ChawlaD, DanielsJL, Benjamin-NeelonSE, et al. Racial and ethnic differences in predictors of vitamin D among pregnant women in south-eastern USA. J Nutr Sci. 2019;28:e8. doi:10.1017/jns.2019.4
  • MerzonE, TworowskiD, GorohovskiA, et al. Low plasma 25(OH) vitamin D level is associated with increased risk of COVID-19 infection: an Israeli population-based study. FEBS J. 2020. doi:10.1111/febs.15495
  • MattioliAV, SciomerS, CocchiC, et al. Quarantine during COVID-19 outbreak: changes in diet and physical activity increase the risk of cardiovascular disease. Nutr Metab Cardiovasc Dis. 2020. doi:10.1016/j.numecd.2020.05.020
  • HalasaN, WilliamsJ, FaouriS, et al. Natural history and epidemiology of respiratory syncytial virus infection in the Middle East: Hospital surveillance for children under age two in Jordan. Vaccine. 2015;33(47):6479–6487. doi:10.1016/j.vaccine.2015.08.04826314623
  • HurwitzJL, JonesBG, PenkertRR, et al. Retinol-binding protein and vitamin D levels are associated with severe outcomes in children hospitalized with lower respiratory tract infection and respiratory syncytial virus or human metapneumovirus detection. J Pediatr. 2017;187:323–327. doi:10.1016/j.jpeds.2017.04.06128578159
  • EzeamamaAE, GuwatuddeD, WangM, et al. Vitamin-D deficiency impairs CD4+ T-cell count recovery rate in HIV-positive adults on highly active antiretroviral therapy: a longitudinal study. Clin Nutr. 2016;35(5):1110–1117. doi:10.1016/j.clnu.2015.08.00726371397
  • LachmannR, BevanMA, KimS, et al. A comparative phase 1 clinical trial to identify anti-infective mechanisms of vitamin D in people with HIV infection. AIDS. 2015;29(10):1127–1135. doi:10.1097/QAD.000000000000066625870995
  • EckardAR, O’RiordanMA, RosebushJC, et al. A vitamin D supplementation decreases immune activation and exhaustion in HIV-1-infected youth. Antivir Ther. 2018;23(4):315–324. doi:10.3851/IMP319928994661
  • TeixeiraNDSCCA, PereiraBM, OliveiraIKF, et al. Effect of vitamin D3 supplementation on HIV-infected adults: a systematic review vitamin D3 supplementation on HIV-infected adults: a systematic review. Nutr Hosp. 2019;36(5):1205–1212. doi:10.20960/nh.0264731526009
  • MohamedAA, SabryNA, AbbassiMM, et al. Vitamin D levels in Egyptian HCV patients (genotype 4) treated with pegylated interferon. Acta Gastroenterol Belg. 2013;76(1):38–44.23650781
  • EltayebAA, AbdouMA, Abdel-aalAM, et al. Vitamin D status and viral response to therapy in hepatitis C infected children. World J Gastroenterol. 2015;21(4):1284–1291. doi:10.3748/wjg.v21.i4.128425632203
  • GreillerCL, MartineauAR. Modulation of the immune response to respiratory viruses by vitamin D. Nutrients. 2015;7(6):4240–4270. doi:10.3390/nu706424026035247
  • JafarzadehA, ChauhanP, SahaB, et al. Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: lessons from SARS and MERS, and potential therapeutic interventions. Life Sci. 2020;257:118102. doi:10.1016/j.lfs.2020.11810232687918
  • SuainiNH, ZhangY, VuillerminPJ, et al. Immune modulation by vitamin D and its relevance to food allergy. Nutrients. 2015;7(8):6088–6108. doi:10.3390/nu708527126225992
  • KebapcilarAG, KulaksizogluM, IpekciSH, et al. Relationship between mean platelet volume and low-grade systemic coagulation with vitamin D deficiency in primary ovarian insufficiency. Arch Gynecol Obstet. 2013;288(1):207–212. doi:10.1007/s00404-013-2735-x23377179
  • YuH, DaiY, HeY. Effects of vitamin D adjuvant intervention on serum 25(OH)D levels in preeclampsia and blood coagulation. Maternal Child HealthC China. 2019;34(16):3664–3667. (in Chinese).
  • HejaziME, Modarresi-GhazaniF, HamishehkarH, et al. The effect of treatment of vitamin D deficiency on the level of P-selectin and hs-CRP in patients with thromboembolism: a pilot randomized clinical trial. J Clin Pharmacol. 2017;57(1):40–47. doi:10.1002/jcph.77427225617
  • FogartyH, TownsendL, Ni CheallaighC, et al. COVID-19 coagulopathy in caucasian patients. Br J Haematol. 2020;189(6):1044–1049. doi:10.1111/bjh.1674932330308
  • RenB, YanF, DengZ, et al. Extremely high incidence of lower extremity deep venous thrombosis in 48 patients with severe COVID-19 in Wuhan. Circulation. 2020;142(2):181–183. doi:10.1161/CIRCULATIONAHA.120.04740732412320
  • TangN, LiD, WangX, et al. Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia. J Thromb Haemost. 2020;18(5):844–847. doi:10.1111/jth.1476832073213
  • TangN, BaiH, ChenX, et al. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost. 2020;18(5):1094–1099. doi:10.1111/jth.1481732220112
  • HathcockJN, ShaoA, ViethR, et al. Risk assessment for vitamin D. Am J Clin Nutr. 2007;85(1):6–18. doi:10.1093/ajcn/85.1.617209171
  • PisoRJ, RothenM, RothenJP, et al. Per oral substitution with 300,000 IU vitamin D (cholecalciferol) reduces bone turnover markers in HIV-infected patients. BMC Infect Dis. 2013;13:577. doi:10.1186/1471-2334-13-57724314015
  • Von RestorffC, Bischoff-FerrariHA, TheilerR. High-dose oral vitamin D3 supplementation in rheumatology patients with severe vitamin D3 deficiency. Bone. 2009;45(4):747–749. doi:10.1016/j.bone.2009.06.01219539796
  • MiriM, KouchekM, Rahat DahmardehA, et al. Effect of high-dose vitamin D on duration of mechanical ventilation in ICU patients. Iran J Pharm Res. 2019;18(2):1067–1072. doi:10.22037/ijpr.2019.110064731531088