H₂O₂-Inactivated Salmonella typhimurium RE88 Strain as a New Cancer Vaccine Carrier: Evaluation in a Mouse Model of Cancer

References

• FrazerIH, LowyDR, SchillerJT. Prevention of cancer through immunization: prospects and challenges for the 21st century. Eur J Immunol. 2007;37(Suppl 1):S148–155. doi:10.1002/eji.20073782017972339
   PubMed Web of Science ®Google Scholar
• AllahverdiyevA, TariG, BagirovaM, AbamorES. Current approaches in development of immunotherapeutic vaccines for breast cancer. J Breast Cancer. 2018;21(4):343–353. doi:10.4048/jbc.2018.21.e4730607155
   PubMed Web of Science ®Google Scholar
• YuYA, ShabahangS, TimiryasovaTM, et al. Visualization of tumors and metastases in live animals with bacteria and vaccinia virus encoding light-emitting proteins. Nat Biotechnol. 2004;22(3):313–320. doi:10.1038/nbt93714990953
   PubMed Web of Science ®Google Scholar
• YiX, ZhouH, ChaoY, et al. Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer. Sci Adv. 2020;6(33):eaba3546.32851163
   PubMed Web of Science ®Google Scholar
• ChowdhuryS, CastroS, CokeretC, et al. Programmable bacteria induce durable tumor regression and systemic antitumor immunity. Nat Med. 2019;25:1057–1063.31270504
   PubMed Web of Science ®Google Scholar
• RizviNA, HellmannMD, SnyderA, et al. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science. 2015;348(6230):124–128.25765070
   PubMed Web of Science ®Google Scholar
• VanAEM, MiaoD, SchillingB, et al. Genomic correlates of response to CTLA-4 blockade in metastatic melanoma. Science. 2015;350(6257):207–211.26359337
   PubMed Web of Science ®Google Scholar
• LeDT, UramJN, WangH, et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med. 2015;372(26):2509–2520.26028255
   PubMed Web of Science ®Google Scholar
• EvansRA, DiamondMS, RechAJ, et al. Lack of immunoediting in murine pancreatic cancer reversed with neoantigen. JCI Insight. 2016;1(14):e88328.
   Web of Science ®Google Scholar
• MougelA, TermeM, TanchotC. Therapeutic cancer vaccine and combinations with antiangiogenic therapies and immune checkpoint blockade. Front Immunol. 2019;10:467. doi:10.3389/fimmu.2019.0046730923527
   PubMed Web of Science ®Google Scholar
• ShenH, MillerJF, FanX, KolwyckD, AhmedR, HartyJT. Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity. Cell. 1998;92(4):535–545. doi:10.1016/S0092-8674(00)80946-09491894
   PubMed Web of Science ®Google Scholar
• SongYC, LiuSJ. A TLR9 agonist enhances the anti-tumor immunity of peptide and lipopeptide vaccines via different mechanisms. Sci Rep. 2015;5:12578. doi:10.1038/srep1257826215533
   PubMed Web of Science ®Google Scholar
• Carretero-IglesiaL, CouturaudB, BaumgaertnerP, et al. High peptide dose vaccination promotes the early selection of tumor antigen-specific CD8 T-cells of enhanced functional competence. Front Immunol. 2019;10:3016. doi:10.3389/fimmu.2019.0301631969886
   PubMed Web of Science ®Google Scholar
• ZhaoZQ, WuB, et al. Subcutaneous vaccination with attenuated Salmonella enterica serovar Choleraesuis C500 expressing recombinant filamentous hemagglutinin and pertactin antigens protects mice against fatal infection with both S. enterica serovar Choleraesuis and Bordetella bronchiseptica. Infect Immun. 2008;76(5):2157–2163. doi:10.1128/IAI.01495-0718268026
   PubMed Web of Science ®Google Scholar
• ZhouS, GravekampC, BermudesD, LiuK. Tumour-targeting bacteria engineered to fight cancer. Nat Rev Cancer. 2018;18(2):727–743.30405213
   PubMed Web of Science ®Google Scholar
• LinIY, VanTT, SmookerPM. Live-attenuated bacterial vectors: tools for vaccine and therapeutic agent delivery. Vaccines. 2015;3(4):940–972. doi:10.3390/vaccines304094026569321
   PubMedGoogle Scholar
• KawaguchiK, IgarashiK, MurakamiT, et al. Salmonella typhimurium A1-R targeting of a chemotherapy-resistant BRAF-V600E melanoma in a patient-derived orthotopic xenograft (PDOX) model is enhanced in combination with either vemurafenib or temozolomide. Cell Cycle. 2017;16(13):1288–1294. doi:10.1080/15384101.2017.131442028622068
   PubMed Web of Science ®Google Scholar
• ChirulloB, AmmendolaS, LeonardiL, et al. Attenuated mutant strain of Salmonella Typhimurium lacking the ZnuABC transporter contrasts tumor growth promoting anti-cancer immune response. Oncotarget. 2015;6(19):17648–17660. doi:10.18632/oncotarget.389326158862
   PubMedGoogle Scholar
• JazayeriSD, IderisA, ZakariaZ, YeapSK, OmarAR. Improved immune responses against avian influenza virus following oral vaccination of chickens with HA DNA vaccine using attenuated Salmonella typhimurium as carrier. Comp Immunol Microbiol Infect Dis. 2012;35(5):417–427. doi:10.1016/j.cimid.2012.03.00722512819
   PubMed Web of Science ®Google Scholar
• MengJZ, DongYJ, HuangH, et al. Oral vaccination with attenuated Salmonella enterica strains encoding T-cell epitopes from tumor antigen NY-ESO-1 induces specific cytotoxic T-lymphocyte responses. Clin Vaccine Immunol. 2010;17(6):889–894. doi:10.1128/CVI.00044-1020375244
   PubMedGoogle Scholar
• WangYJ, HouY, HuangH, LiuGR, WhiteAP, LiuSL. Two oral HBx vaccines delivered by live attenuated Salmonella: both eliciting effective anti-tumor immunity. Cancer Lett. 2008;263(1):67–76. doi:10.1016/j.canlet.2007.12.02218226855
   PubMed Web of Science ®Google Scholar
• TianY, GuoB, JiaH, et al. Targeted therapy via oral administration of attenuated Salmonella expression plasmid-vectored Stat3-shRNA cures orthotopically transplanted mouse HCC. Cancer Gene Ther. 2012;19(6):393–401. doi:10.1038/cgt.2012.1222555509
   PubMed Web of Science ®Google Scholar
• GentschevI, FensterleJ, SchmidtA, et al. Use of a recombinant Salmonella enterica serovar Typhimurium strain expressing C-Raf for protection against C-Raf induced lung adenoma in mice. BMC Cancer. 2005;5:15. doi:10.1186/1471-2407-5-1515703070
   PubMed Web of Science ®Google Scholar
• XiangR, MizutaniN, LuoY, et al. A DNA vaccine targeting survivin combines apoptosis with suppression of angiogenesis in lung tumor eradication. Cancer Res. 2005;65(2):553–561.15695399
   PubMed Web of Science ®Google Scholar
• LeeSH, MizutaniN, MizutaniM, et al. Endoglin (CD105) is a target for an oral DNA vaccine against breast cancer. Cancer Immunol Immunother. 2006;55(12):1565–1574. doi:10.1007/s00262-006-0155-516565828
   PubMed Web of Science ®Google Scholar
• LewenS, ZhouH, HuHD, et al. A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis. Cancer Immunol Immunother. 2008;57(4):507–515. doi:10.1007/s00262-007-0389-x17786443
   PubMed Web of Science ®Google Scholar
• KondouK, SuzukiT, ChangMO, TakakuH. Recombinant baculovirus expressing the FrC-OVA protein induces protective antitumor immunity in an EG7-OVA mouse model. J Biol Eng. 2019;13:77. doi:10.1186/s13036-019-0207-y31649751
   PubMed Web of Science ®Google Scholar
• KimNW, KimSY, LeeJE, et al. Enhanced cancer vaccination by in situ nanomicelle-generating dissolving microneedles. ACS Nano. 2018;12(10):9702–9713. doi:10.1021/acsnano.8b0414630141896
   PubMed Web of Science ®Google Scholar
• UmekiY, SaitoM, TakahashiY, TakakuraY, NishikawaM. Retardation of antigen release from DNA hydrogel using cholesterol-modified DNA for increased antigen-specific immune response. Adv Healthc Mater. 2017;6:20. doi:10.1002/adhm.201700355
   Web of Science ®Google Scholar
• LeeSJ, KimJJ, KangKY, PaikMJ, LeeG, YeeST. Enhanced anti-tumor immunotherapy by silica-coated magnetic nanoparticles conjugated with ovalbumin. Int J Nanomedicine. 2019;14:8235–8249. doi:10.2147/IJN.S19435231802864
   PubMed Web of Science ®Google Scholar
• FanY, MuY, LuL, et al. Hydrogen peroxide-inactivated bacteria induces potent humoral and cellular immune responses and releases nucleic acids. Int Immunopharmacol. 2019;69:389–397. doi:10.1016/j.intimp.2019.01.05530780019
   PubMed Web of Science ®Google Scholar
• StarkFC, SadS, KrishnanL. Intracellular bacterial vectors that induce CD8(+) T cells with similar cytolytic abilities but disparate memory phenotypes provide contrasting tumor protection. Cancer Res. 2009;69(10):4327. doi:10.1158/0008-5472.CAN-08-316019435919
   PubMed Web of Science ®Google Scholar
• JazaniNH, SohrabpourM, MazloomiE, ShahabiS. A novel adjuvant, a mixture of alum and the general opioid antagonist naloxone, elicits both humoral and cellular immune responses for heat-killed Salmonella typhimurium vaccine. FEMS Immunol Med Microbiol. 2011;61(1):54–62. doi:10.1111/j.1574-695X.2010.00747.x21054579
   PubMedGoogle Scholar
• ChristophJ, BinderC, Papac-MilicevicN, JosephL. Witztum, Innate sensing of oxidation-specific epitopes in health and disease. Nat Rev Immunol. 2016;16(8):485–497.27346802
   PubMed Web of Science ®Google Scholar