Breviscapine Pretreatment Inhibits Myocardial Inflammation and Apoptosis in Rats After Coronary Microembolization by Activating the PI3K/Akt/GSK-3β Signaling Pathway

References

• HeuschG, SkyschallyA, KleinbongardP. Coronary microembolization and microvascular dysfunction. Int J Cardiol. 2018;258:17–23. doi:10.1016/j.ijcard.2018.02.01029429637
   PubMed Web of Science ®Google Scholar
• OttoS, SeeberM, FujitaB, et al. Microembolization and myonecrosis during elective percutaneous coronary interventions in diabetic patients: an intracoronary doppler ultrasound study with 2-year clinical follow-up. Basic Res Cardiol. 2012;107(5):289. doi:10.1007/s00395-012-0289-x22850870
   PubMed Web of Science ®Google Scholar
• LiuY, LiuY, HuangX, ZhangJ, YangL. Protective effects and mechanism of curcumin on myocardial injury induced by coronary microembolization. J Cell Biochem. 2019;120(4):5695–5703. doi:10.1002/jcb.2785430324684
   PubMed Web of Science ®Google Scholar
• WangJY, ChenH, SuX, ZhouY, LiL. Atorvastatin pretreatment inhibits myocardial inflammation and apoptosis in swine after coronary microembolization. J Cardiovasc Pharmacol Ther. 2017;22(2):189–195. doi:10.1177/107424841666234827587240
   PubMed Web of Science ®Google Scholar
• LiangJ, LiL, SunY, HeW, WangX, SuQ. The protective effect of activating Nrf2/HO-1 signaling pathway on cardiomyocyte apoptosis after coronary microembolization in rats. BMC Cardiovasc Disord. 2017;17(1):272. doi:10.1186/s12872-017-0704-129065851
   PubMed Web of Science ®Google Scholar
• KongB, QinZ, YeZ, YangX, LiL, SuQ. microRNA-26a-5p affects myocardial injury induced by coronary microembolization by modulating HMGA1. J Cell Biochem. 2019;120(6):10756–10766. doi:10.1002/jcb.2836730652345
   PubMed Web of Science ®Google Scholar
• SuQ, LvX, YeZ. Ligustrazine attenuates myocardial injury induced by coronary microembolization in rats by activating the PI3K/Akt pathway. Oxid Med Cell Longev. 2019;2019:6791457. doi:10.1155/2019/679145731191802
   PubMed Web of Science ®Google Scholar
• GaoJ, ChenG, HeH, et al. Therapeutic effects of breviscapine in cardiovascular diseases: a review. Front Pharmacol. 2017;8:289. doi:10.3389/fphar.2017.0028928588491
   PubMed Web of Science ®Google Scholar
• YanL, HuangH, TangQZ, et al. Breviscapine protects against cardiac hypertrophy through blocking PKC-alpha-dependent signaling. J Cell Biochem. 2010;109(6):1158–1171. doi:10.1002/jcb.2249520127712
   PubMed Web of Science ®Google Scholar
• JiaJH, ChenKP, ChenSX, LiuKZ, FanTL, ChenYC. Breviscapine, a traditional Chinese medicine, alleviates myocardial ischaemia reperfusion injury in diabetic rats. Acta Cardiol. 2008;63(6):757–762. doi:10.2143/AC.63.6.203339419157172
   PubMed Web of Science ®Google Scholar
• LiXL, LiYQ, YanWM, et al. A study of the cardioprotective effect of breviscapine during hypoxia of cardiomyocytes. Planta Med. 2004;70(11):1039–1044. doi:10.1055/s-2004-83264415549659
   PubMed Web of Science ®Google Scholar
• WangM, ZhangWB, SongJL, LuanY, JinCY. Effect of breviscapine on recovery of viable myocardium and left ventricular remodeling in chronic total occlusion patients after revascularization: rationale and design for a randomized controlled trial. Med Sci Monit. 2018;24:4602–4609. doi:10.12659/MSM.90643829970875
   PubMed Web of Science ®Google Scholar
• ZhangH, SongY, LiZ, ZhangT, ZengL. Evaluation of breviscapine on prevention of experimentally induced abdominal adhesions in rats. Am J Surg. 2016;211(6):1143–1152. doi:10.1016/j.amjsurg.2015.05.03726394920
   PubMed Web of Science ®Google Scholar
• WangJ, JiSY, LiuSZ, JingR, LouWJ. Cardioprotective effect of breviscapine: inhibition of apoptosis in H9c2 cardiomyocytes via the PI3K/Akt/eNOS pathway following simulated ischemia/reperfusion injury. Die Pharmazie. 2015;70(9):593–597.26492644
   PubMed Web of Science ®Google Scholar
• ZhongD, YangB, ChenX, LiK, XuJ. Determination of scutellarin in rat plasma by high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2003;796(2):439–444. doi:10.1016/j.jchromb.2003.08.002
   Web of Science ®Google Scholar
• MaoQ, LiangX, WuY, LuY. Resveratrol attenuates cardiomyocyte apoptosis in rats induced by coronary microembolization through SIRT1-mediated deacetylation of p53. J Cardiovasc Pharmacol Ther. 2019;24(6):551–558. doi:10.1177/107424841984591631046448
   PubMed Web of Science ®Google Scholar
• SuQ, LvX, SunY, YeZ, KongB, QinZ. Role of TLR4/MyD88/NF-kappaB signaling pathway in coronary microembolization-induced myocardial injury prevented and treated with nicorandil. Biomed Pharmacother. 2018;106:776–784. doi:10.1016/j.biopha.2018.07.01429990871
   PubMed Web of Science ®Google Scholar
• ZhuHH, WangXT, SunYH, et al. MicroRNA-486-5p targeting PTEN protects against coronary microembolization-induced cardiomyocyte apoptosis in rats by activating the PI3K/AKT pathway. Eur J Pharmacol. 2019;855:244–251. doi:10.1016/j.ejphar.2019.03.04531075240
   PubMed Web of Science ®Google Scholar
• ChenQF, WangW, HuangZ, et al. Role of high-mobility group B1 in myocardial injury induced by coronary microembolization in rats. J Cell Biochem. 2019;120(3):4238–4247. doi:10.1002/jcb.2770930269353
   PubMed Web of Science ®Google Scholar
• BoseD, von BirgelenC, ZhouXY, et al. Impact of atherosclerotic plaque composition on coronary microembolization during percutaneous coronary interventions. Basic Res Cardiol. 2008;103(6):587–597. doi:10.1007/s00395-008-0745-918787802
   PubMed Web of Science ®Google Scholar
• DorgeH, NeumannT, BehrendsM, et al. Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation. Am J Physiol Heart Circ Physiol. 2000;279(6):H2587–H2592. doi:10.1152/ajpheart.2000.279.6.H258711087208
   PubMed Web of Science ®Google Scholar
• SunYH, SuQ, LiL, WangXT, LuYX, LiangJB. Expression of p53 in myocardium following coronary microembolization in rats and its significance. J Geriatr Cardiol. 2017;14(5):292–300. doi:10.11909/j.issn.1671-5411.2017.05.00728630604
   PubMedGoogle Scholar
• SuQ, LvX, SunY, YangH, YeZ, LiL. Role of high mobility group A1/nuclear factor-kappa B signaling in coronary microembolization-induced myocardial injury. Biomed Pharmacother. 2018;105:1164–1171. doi:10.1016/j.biopha.2018.06.09830021353
   PubMed Web of Science ®Google Scholar
• GuanYB, YangDR, NongSJ, et al. Breviscapine (BVP) inhibits prostate cancer progression through damaging DNA by minichromosome maintenance protein-7 (MCM-7) modulation. Biomed Pharmacother. 2017;93:103–116. doi:10.1016/j.biopha.2017.06.02428628830
   PubMed Web of Science ®Google Scholar
• GuoC, ZhuY, WengY, et al. Therapeutic time window and underlying therapeutic mechanism of breviscapine injection against cerebral ischemia/reperfusion injury in rats. J Ethnopharmacol. 2014;151(1):660–666. doi:10.1016/j.jep.2013.11.02624291152
   PubMed Web of Science ®Google Scholar
• HongH, LiuGQ. Scutellarin attenuates oxidative glutamate toxicity in PC12 cells. Planta Med. 2004;70(5):427–431.15124087
   PubMed Web of Science ®Google Scholar
• WuL, LiuM, FangZ. Combined therapy of hypertensive nephropathy with breviscapine injection and antihypertensive drugs: a systematic review and a meta-analysis. Evid Based Complement Alternat Med. 2018;2018:2958717. doi:10.1155/2018/295871730671127
   PubMed Web of Science ®Google Scholar
• JiangL, XiaQJ, DongXJ, et al. Neuroprotective effect of breviscapine on traumatic brain injury in rats associated with the inhibition of GSK3beta signaling pathway. Brain Res. 2017;1660:1–9. doi:10.1016/j.brainres.2017.01.03128143715
   PubMed Web of Science ®Google Scholar
• LiuY, WenPH, ZhangXX, DaiY, HeQ. Breviscapine ameliorates CCl4induced liver injury in mice through inhibiting inflammatory apoptotic response and ROS generation. Int J Mol Med. 2018;42(2):755–768. doi:10.3892/ijmm.2018.365129717768
   PubMed Web of Science ®Google Scholar
• BaoZ, ChenW, PanF, PengB, GongJ. Role of mitofusin 2 in the protective effect of breviscapine against hepatic ischemia/reperfusion injury in rats. Exp Ther Med. 2018;15(4):3582–3588. doi:10.3892/etm.2018.583429545887
   PubMed Web of Science ®Google Scholar
• YimingL, WeiH, AihuaL, FandianZ. Neuroprotective effects of breviscapine against apoptosis induced by transient focal cerebral ischaemia in rats. J Pharm Pharmacol. 2008;60(3):349–355. doi:10.1211/jpp.60.3.001018284815
   PubMed Web of Science ®Google Scholar
• SuQ, LiL, ZhaoJ, SunY, YangH. Effects of nicorandil on PI3K/Akt signaling pathway and its anti-apoptotic mechanisms in coronary microembolization in rats. Oncotarget. 2017;8(59):99347–99358. doi:10.18632/oncotarget.1996629245906
   PubMedGoogle Scholar
• MaoQ, LiangX, WuY, LuY. Nobiletin protects against myocardial injury and myocardial apoptosis following coronary microembolization via activating PI3K/Akt pathway in rats. Naunyn Schmiedebergs Arch Pharmacol. 2019;392(9):1121–1130. doi:10.1007/s00210-019-01661-y31073648
   PubMed Web of Science ®Google Scholar
• KimSA, KangOH, KwonDY. Cryptotanshinone induces cell cycle arrest and apoptosis of NSCLC cells through the PI3K/Akt/GSK-3beta pathway. Int J Mol Sci. 2018;19(9). doi:10.3390/ijms19092739
   Web of Science ®Google Scholar
• ZhangX, ShiM, YeR, et al. Ginsenoside Rd attenuates tau protein phosphorylation via the PI3K/AKT/GSK-3beta pathway after transient forebrain ischemia. Neurochem Res. 2014;39(7):1363–1373. doi:10.1007/s11064-014-1321-324792734
   PubMed Web of Science ®Google Scholar
• ParkSJ, JinML, AnHK, et al. Emodin induces neurite outgrowth through PI3K/Akt/GSK-3beta-mediated signaling pathways in Neuro2a cells. Neurosci Lett. 2015;588:101–107. doi:10.1016/j.neulet.2015.01.00125562207
   PubMed Web of Science ®Google Scholar
• ZhengT, YangX, WuD, et al. Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3beta pathway. Br J Pharmacol. 2015;172(13):3284–3301. doi:10.1111/bph.1312025754463
   PubMed Web of Science ®Google Scholar
• ZhangY, ZhangZ, WangH, et al. Neuroprotective effect of ginsenoside Rg1 prevents cognitive impairment induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3beta pathway. Mol Med Rep. 2016;14(3):2778–2784. doi:10.3892/mmr.2016.555627485139
   PubMed Web of Science ®Google Scholar
• WeiD, XuH, GaiX, JiangY. Astragaloside IV alleviates myocardial ischemia-reperfusion injury in rats through regulating PI3K/AKT/GSK-3beta signaling pathways. Acta Cir Bras. 2019;34(7):e201900708. doi:10.1590/s0102-86502019007000000831531541
   PubMed Web of Science ®Google Scholar
• ZhangL, GuoZ, WangY, GengJ, HanS. The protective effect of kaempferol on heart via the regulation of Nrf2, NF-κβ, and PI3K/Akt/GSK-3β signaling pathways in isoproterenol-induced heart failure in diabetic rats. Drug Dev Res. 2019;80(3):294–309. doi:10.1002/ddr.2149530864233
   PubMed Web of Science ®Google Scholar
• TsukaharaS, YamamotoS, Tin Tin WinS, et al. Inhalation of low-level formaldehyde increases the Bcl-2/Bax expression ratio in the hippocampus of immunologically sensitized mice. Neuroimmunomodulation. 2006;13(2):63–68. doi:10.1159/00009482916888403
   PubMed Web of Science ®Google Scholar