References
- NgLC, LeeYY, LeeCK, WongSM. A retrospective review of methotrexate-induced hepatotoxicity among patients with psoriasis in a tertiary dermatology center in Malaysia. Int J Dermatol. 2013;52(1):102–105. doi:10.1111/j.1365-4632.2011.05436.x23278617
- MillerDW, FeldmanSR. Cost-effectiveness of moderate-to-severe psoriasis treatment. Expert Opin Pharmacother. 2006;7(2):157–167. doi:10.1517/14656566.7.2.15716433581
- MenterA, KormanNJ, ElmetsCA, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: section 4. Guidelines of care for the management and treatment of psoriasis with traditional systemic agents. J Am Acad Dermatol. 2009;61(3):451–485. doi:10.1016/j.jaad.2009.03.02719493586
- PrussickRB, MieleL. Nonalcoholic fatty liver disease in patients with psoriasis: a consequence of systemic inflammatory burden? Br J Dermatol. 2018;179(1):16–29. doi:10.1111/bjd.1623929235656
- LeeCS, LiK. A review of acitretin for the treatment of psoriasis. Expert Opin Drug Saf. 2009;8(6):769–779. doi:10.1517/1474033090339373219998529
- RoenigkHH Jr. Acitretin combination therapy. J Am Acad Dermatol. 1999;41(3 Pt 2):S18–S21. doi:10.1016/S0190-9622(99)70361-010459142
- MenterA, GelfandJM, ConnorC, et al. Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management of psoriasis with systemic nonbiologic therapies. J Am Acad Dermatol. 2020;82(6):1445–1486. doi:10.1016/j.jaad.2020.02.04432119894
- OrmerodAD, CampalaniE, GoodfieldMJ. British Association of Dermatologists guidelines on the efficacy and use of acitretin in dermatology. Br J Dermatol. 2010;162(5):952–963. doi:10.1111/j.1365-2133.2010.09755.x20423353
- NastA, SmithC, SpulsPI, et al. EuroGuiDerm guideline on the systemic treatment of Psoriasis vulgaris - Part 1: treatment and monitoring recommendations. J Eur Acad Dermatol Venereol. 2020;34(11):2461–2498. doi:10.1111/jdv.1691533349983
- NastA, AmelunxenL, AugustinM, et al. S3 guideline for the treatment of psoriasis vulgaris, update - short version part 1 - systemic treatment. J Dtsch Dermatol Ges. 2018;16(5):645–669.
- CarreteroG, RiberaM, BelinchónI, et al. Guidelines for the use of acitretin in psoriasis. Psoriasis Group of the Spanish Academy of Dermatology and Venereology. Actas Dermosifiliogr. 2013;104(7):598–616. doi:10.1016/j.ad.2013.01.00323891453
- ArnoneM, TakahashiMDF, CarvalhoAVE, et al. Diagnostic and therapeutic guidelines for plaque psoriasis - Brazilian Society of Dermatology. An Bras Dermatol. 2019;94(2 Suppl 1):76–107. doi:10.1590/abd1806-4841.2019940211
- LowenthalKE, HornPJ, KalbRE. Concurrent use of methotrexate and acitretin revisited. J Dermatolog Treat. 2008;19(1):22–26. doi:10.1080/0954663070175957918273721
- HodulikSG, ZeichnerJA. Combination therapy with acitretin for psoriasis. J Dermatolog Treat. 2006;17(2):108–111. doi:10.1080/0954663060063298416766335
- AnJ, ZhangD, WuJ, et al. The acitretin and methotrexate combination therapy for psoriasis vulgaris achieves higher effectiveness and less liver fibrosis. Pharmacol Res. 2017;121:158–168. doi:10.1016/j.phrs.2017.04.01428414177
- PinyowiwatP, RattanakaemakornP, IamsumangW. 15111 Incidence of hepatic fibrosis in psoriasis patients receiving methotrexate and acitretin combination therapy in a tertiary-care hospital in Thailand. J Am Acad Dermatol. 2020;83(6):AB141. doi:10.1016/j.jaad.2020.06.654
- KalbRE, StroberB, WeinsteinG, LebwohlM. Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference. J Am Acad Dermatol. 2009;60(5):824–837. doi:10.1016/j.jaad.2008.11.90619389524
- ParkSH, ChoeJY, KimSK. Assessment of liver fibrosis by transient elastography in rheumatoid arthritis patients treated with methotrexate. Joint Bone Spine. 2010;77(6):588–592. doi:10.1016/j.jbspin.2010.02.02420471892
- GengXX, HuangRG, LinJM, JiangN, YangXX. Transient elastography in clinical detection of liver cirrhosis: a systematic review and meta-analysis. Saudi J Gastroenterol. 2016;22(4):294–303. doi:10.4103/1319-3767.18760327488324
- Organization WH. World Health Organization: international guide for monitoring alcohol consumption and related harm; 2000. Available from: https://apps.who.int/iris/bitstream/handle/10665/66529/WHO_MSD_MSB_00.4.pdf?sequence=1&isAllowed=y. Accessed 126, 2021.
- WongVW, VergniolJ, WongGL, et al. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology. 2010;51(2):454–462. doi:10.1002/hep.2331220101745
- MayburyCM, Jabbar-LopezZK, WongT, DhillonAP, BarkerJN, SmithCH. Methotrexate and liver fibrosis in people with psoriasis: a systematic review of observational studies. Br J Dermatol. 2014;171(1):17–29. doi:10.1111/bjd.12941
- BathRK, BrarNK, ForouharFA, WuGY. A review of methotrexate-associated hepatotoxicity. J Dig Dis. 2014;15(10):517–524. doi:10.1111/1751-2980.1218425139707
- ChengHS, RademakerM. Monitoring methotrexate-induced liver fibrosis in patients with psoriasis: utility of transient elastography. Psoriasis. 2018;8:21–29. doi:10.2147/PTT.S14162929785393
- SilvaFS, RibeiroMP, SantosMS, Rocha-PereiraP, Santos-SilvaA, CustódioJB. Acitretin affects bioenergetics of liver mitochondria and promotes mitochondrial permeability transition: potential mechanisms of hepatotoxicity. Toxicology. 2013;306:93–100. doi:10.1016/j.tox.2013.01.02023384448
- BelinskyGS, ParkeAL, HuangQ, et al. The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol Sci. 2007;97(2):582–594. doi:10.1093/toxsci/kfm06717400583
- WestSG. Methotrexate hepatotoxicity. Rheum Dis Clin North Am. 1997;23(4):883–915. doi:10.1016/S0889-857X(05)70365-39361160
- PanebiancoC, ObenJA, VinciguerraM, PazienzaV. Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings. Clin Exp Med. 2017;17(3):269–280. doi:10.1007/s10238-016-0438-x27655446
- SuchonwanitP, HectorCE, Bin SaifGA, McMichaelAJ. Factors affecting the severity of central centrifugal cicatricial alopecia. Int J Dermatol. 2016;55(6):e338–e343. doi:10.1111/ijd.1306126769173
- HarnchoowongS, SuchonwanitP. PPAR-γ agonists and their role in primary cicatricial alopecia. PPAR Res. 2017;2017:2501248. doi:10.1155/2017/250124829333153
- BerendsMA, SnoekJ, de JongEM, et al. Liver injury in long-term methotrexate treatment in psoriasis is relatively infrequent. Aliment Pharmacol Ther. 2006;24(5):805–811. doi:10.1111/j.1365-2036.2006.03047.x16918884
- LindsayK, FraserAD, LaytonA, GoodfieldM, GrussH, GoughA. Liver fibrosis in patients with psoriasis and psoriatic arthritis on long-term, high cumulative dose methotrexate therapy. Rheumatology. 2009;48(5):569–572. doi:10.1093/rheumatology/kep02319273538
- RabinowichL, ShiboletO. Drug induced steatohepatitis: an uncommon culprit of a common disease. Biomed Res Int. 2015;2015:168905. doi:10.1155/2015/16890526273591
- SchmajukG, MiaoY, YazdanyJ, BoscardinWJ, DaikhDI, SteinmanMA. Identification of risk factors for elevated transaminases in methotrexate users through an electronic health record. Arthritis Care Res. 2014;66(8):1159–1166. doi:10.1002/acr.22294
- FromentyB. Drug-induced liver injury in obesity. J Hepatol. 2013;58(4):824–826. doi:10.1016/j.jhep.2012.12.01823298629
- ShettyA, ChoW, AlazawiW, SynWK. Methotrexate hepatotoxicity and the impact of nonalcoholic fatty liver disease. Am J Med Sci. 2017;354(2):172–181. doi:10.1016/j.amjms.2017.03.01428864376
- TalmeT, NikamoP, RosenbergP, StahleM. Transient elastography may improve detection of liver fibrosis in psoriasis patients treated with methotrexate. Acta Derm Venereol. 2017;97(8):952–954. doi:10.2340/00015555-267728422266
- MontaudieH, SbidianE, PaulC, et al. Methotrexate in psoriasis: a systematic review of treatment modalities, incidence, risk factors and monitoring of liver toxicity. J Eur Acad Dermatol Venereol. 2011;25(Suppl 2):12–18. doi:10.1111/j.1468-3083.2011.03991.x
- DawwasMF, AithalGP. End-stage methotrexate-related liver disease is rare and associated with features of the metabolic syndrome. Aliment Pharmacol Ther. 2014;40(8):938–948. doi:10.1111/apt.1291225185870
- ChanprapaphK, PratumchartN, LimtongP, et al. Dipeptidyl peptidase-4 inhibitor-related bullous pemphigoid: a comparative study of 100 patients with bullous pemphigoid and diabetes mellitus. J Dermatol. 2021;48(4):486–496. doi:10.1111/1346-8138.1577833543537
- OgdieA, GrewalSK, NoeMH, et al. Risk of incident liver disease in patients with psoriasis, psoriatic arthritis, and rheumatoid arthritis: a population-based study. J Invest Dermatol. 2018;138(4):760–767. doi:10.1016/j.jid.2017.10.02429104161
- MadanagobalaneS, AnandanS. The increased prevalence of non-alcoholic fatty liver disease in psoriatic patients: a study from South India. Australas J Dermatol. 2012;53(3):190–197. doi:10.1111/j.1440-0960.2012.00905.x22672067
- CandiaR, RuizA, Torres-RoblesR, Chavez-TapiaN, Mendez-SanchezN, ArreseM. Risk of non-alcoholic fatty liver disease in patients with psoriasis: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol. 2015;29(4):656–662. doi:10.1111/jdv.1284725418531
- MantovaniA, GisondiP, LonardoA, TargherG. Relationship between non-alcoholic fatty liver disease and psoriasis: a novel hepato-dermal axis? Int J Mol Sci. 2016;17(2):217. doi:10.3390/ijms1702021726861300
- GisondiP, BarbaE, GirolomoniG. Non-alcoholic fatty liver disease fibrosis score in patients with psoriasis. J Eur Acad Dermatol Venereol. 2016;30(2):282–287. doi:10.1111/jdv.1345626537011
- ChanprapaphK, TubtiengI, PratumchatN, ThadaniponK, RattanakaemakornP, SuchonwanitP. Cutaneous, systemic features and laboratory characteristics of late- versus adult-onset systemic lupus erythematosus in 1006 Thai patients. Lupus. 2021;30(5):785–794. doi:10.1177/096120332199192033554715
- ChanasumonN, SriphojanartT, SuchonwanitP. Therapeutic potential of bimatoprost for the treatment of eyebrow hypotrichosis. Drug Des Devel Ther. 2018;12:365–372. doi:10.2147/DDDT.S156467
- SriphojanartT, KhunkhetS, SuchonwanitP. A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata. Dermatol Rep. 2017;9(2):7399. doi:10.4081/dr.2017.7399
- RattanakaemakornP, PhusuphitchayananP, PakornphadungsitK, ThadaniponK, SuchonwanitP. Efficacy and safety of 308-nm excimer lamp in the treatment of scalp psoriasis: a retrospective study. Photodermatol Photoimmunol Photomed. 2019;35(3):172–177. doi:10.1111/phpp.1244830648290
- AithalGP, HaugkB, DasS, CardT, BurtAD, RecordCO. Monitoring methotrexate-induced hepatic fibrosis in patients with psoriasis: are serial liver biopsies justified? Aliment Pharmacol Ther. 2004;19(4):391–399. doi:10.1046/j.1365-2036.2004.01819.x14871278
- PongpitJ, PorntharukchareonS, KaewduangP, et al. Liver stiffness measurement in psoriasis: do metabolic or disease factors play the important role? Biomed Res Int. 2016;2016:7963972. doi:10.1155/2016/796397227006950
- RosenbergP, UrwitzH, JohannessonA, et al. Psoriasis patients with diabetes type 2 are at high risk of developing liver fibrosis during methotrexate treatment. J Hepatol. 2007;46(6):1111–1118. doi:10.1016/j.jhep.2007.01.02417399848