Immunoregulatory Effect of Acanthopanax trifoliatus (L.) Merr. Polysaccharide on T1DM Mice

References

• SteckAK, WinterWE. Review on monogenic diabetes. Curr Opin Endocrinol Diabetes Obes. 2011;18(4):252–258. doi:10.1097/MED.0b013e328348827521844708
   PubMedGoogle Scholar
• International Diabetes Federation. IDF Diabetes Atlas. 8th edition ed. Belgium: International Diabetes Federation; 2017. Available from: http//www.diabetesatlas.org.
   Google Scholar
• ChenX, TangJ, XieW, et al. Protective effect of the polysaccharide from ophiopogon japonicus on streptozotocin-induced diabetic rats. Carbohydr Polym. 2013;94(1):378–385. doi:10.1016/j.carbpol.2013.01.03723544552
   PubMed Web of Science ®Google Scholar
• SætherT, PaulsenSM, TungenJE, et al. Synthesis and biological evaluations of marine oxohexadecenoic acids: pPARα/γ dual agonism and anti-diabetic target gene effects. Eur J Med Chem. 2018;155:736–753. doi:10.1016/j.ejmech.2018.06.03429940464
   PubMed Web of Science ®Google Scholar
• SamedN, SharmaV, SundaramurthyA. Hydrogen bonded niosomes for encapsulation and release of hydrophilic and hydrophobic anti-diabetic drugs: an efficient system for oral anti-diabetic formulation. Appl Surf Sci. 2018;449:567–573. doi:10.1016/j.apsusc.2017.11.055
   Web of Science ®Google Scholar
• WangD, ZhaoY, JiaoY, YuL, YangS, YangX. Antioxidative and hepatoprotective effects of the polysaccharides from Zizyphus jujube cv. Shaanbeitanzao. Carbohydr Polym. 2012;88(4):1453–1459. doi:10.1016/j.carbpol.2012.02.046
   Web of Science ®Google Scholar
• WangD, ZhaoY, SunY, YangX. Protective effects of Ziyang tea polysaccharides on CCl4-induced oxidative liver damage in mice. Food Chem. 2014;143:371–378. doi:10.1016/j.foodchem.2013.08.00524054254
   PubMed Web of Science ®Google Scholar
• FuQY, LiQS, LinXM, et al. Antidiabetic effects of tea. Molecules. 2017;22(5):849. doi:10.3390/molecules22050849
   Web of Science ®Google Scholar
• LiaoCH, LinJY. Lotus (Nelumbo nucifera Gaertn) plumule polysaccharide ameliorates pancreatic islets loss and serum lipid profiles in non-obese diabetic mice. Food Chem Toxicol. 2013;58:416–422. doi:10.1016/j.fct.2013.05.01823707471
   PubMed Web of Science ®Google Scholar
• ZhaoL, WangK, WangK, ZhuJ, HuZY. Nutrient components, health benefits, and safety of litchi (Litchi chinensis Sonn.): a review. Compr Rev Food Sci Food Saf. 2020;19(4):2139–2163. doi:10.1111/1541-4337.1259033337091
   PubMed Web of Science ®Google Scholar
• JiaRB, LiZR, WuJ, et al. Antidiabetic effects and underlying mechanisms of anti-digestive dietary polysaccharides from Sargassum fusiforme in rats. Food Funct. 2020;11(8):7023–7036. doi:10.1039/d0fo01166e32716443
   PubMed Web of Science ®Google Scholar
• BhatejaPK, KajalA, SinghR. Amelioration of Diabetes mellitus by modulation of GLP-1 via targeting alpha-glucosidase using Acacia tortilis polysaccharide in Streptozotocin-Nicotinamide induced diabetes in rats. J Ayurveda Integr Med. 2020;11(4):405–413. doi:10.1016/j.jaim.2019.06.00333153880
   PubMed Web of Science ®Google Scholar
• eFloras. Flora of China, Missouri Botanical Garde. MA: St. Louis, MO & Harvard University Herbaria; 2014.
   Google Scholar
• HuangKC, Michael WilliamsW. The Pharmacology of Chinese Herbs. Vol. 874. New York: CRC Press LLC; 1999.
   Google Scholar
• BucciLR. Selected herbals and human exercise performance. Am J Clin Nutr. 2000;72(2):624S–636S. doi:10.1093/ajcn/72.2.624S10919969
   PubMed Web of Science ®Google Scholar
• SchultesRE. Medicinal plants of east and southeast Asia. MIT Press, Cambridge. J Ethnopharmacol. 1981;4(1):124. doi:10.1016/0378-8741(81)90028-3
   Google Scholar
• LiD-L, ZhengX, ChenY-C, et al. Terpenoid composition and the anticancer activity of Acanthopanax trifoliatus. Arch Pharm Res. 2016;39(1):51–58. doi:10.1007/s12272-015-0655-y26345267
   PubMed Web of Science ®Google Scholar
• WangHQ, LiDL, LuYJ, et al. Anticancer activity of Acanthopanax trifoliatus (L) Merr extracts is associated with inhibition of NF-kB activity and decreased Erk1/2 and Akt phosphorylation. Asian Pac J Cancer Prev. 2014;15(21):9341–9346. doi:10.7314/apjcp.2014.15.21.934125422222
   PubMedGoogle Scholar
• HamidR, KeeT, OthmanF. Anti-inflammatory and anti-hyperalgesic activities of Acanthopanax trifoliatus (L) Merr leaves. Pharmacognosy Res. 2013;5(2):129–133. doi:10.4103/0974-8490.11054423798889
   PubMedGoogle Scholar
• SithisarnP, RojsangaP, JarikasemS, TanakaK, MatsumotoK. Ameliorative effects of acanthopanax trifoliatus on cognitive and emotional deficits in olfactory bulbectomized mice: an animal model of depression and cognitive deficits. Evid Based Complement Alternat Med. 2013;2013:701956. doi:10.1155/2013/70195623573147
   PubMed Web of Science ®Google Scholar
• LoJ, XiaC-Q, PengR, Clare-SalzlerMJ. Immature dendritic cell therapy confers durable immune modulation in an antigen-dependent and antigen-independent manner in nonobese diabetic mice. J Immunol Res. 2018;2018:5463879. doi:10.1155/2018/5463879.29651443
   PubMed Web of Science ®Google Scholar
• KangH, AhnK-S, ChoC, BaeH-S. Immunomodulatory effect of astragali radix extract on murine Th1/Th2 cell lineage development. Biol Pharm Bull. 2004;27(12):1946–1950. doi:10.1248/bpb.27.194615577210
   PubMed Web of Science ®Google Scholar
• ChengXX, ZhangXH, YangHW. Isolation, purification and anti-oxidant activity of polysaccharides from Acanthopanax trifoliatus. Chin Tradit Herb Drugs. 2017;48:4219–4223. doi:10.7501/j.issn.0253-2670.2017.20.015
   Google Scholar
• YaochiteJNU, Caliari-OliveiraC, DavansoMR, et al. Dynamic changes of the Th17/Tc17 and regulatory T cell populations interfere in the experimental autoimmune diabetes pathogenesis. Immunobiology. 2013;218(3):338–352. doi:10.1016/j.imbio.2012.05.01022704522
   PubMed Web of Science ®Google Scholar
• MüllerA, Schott-OhlyP, DohleC, GleichmannH. Differential regulation of Th1-Type and Th2-type cytokine profiles in pancreatic islets of C57BL/6 and BALB/c mice by multiple low doses of streptozotocin. Immunobiology. 2002;205(1):35–50. doi:10.1078/0171-2985-0010911999343
   PubMed Web of Science ®Google Scholar
• Mensah-BrownEPK, Stosic GrujicicS, MaksimovicD, JasimaA, ShahinA, LukicML. Downregulation of apoptosis in the target tissue prevents low-dose streptozotocin-induced autoimmune diabetes. Mol Immunol. 2002;38(12):941–946. doi:10.1016/S0161-5890(02)00021-412009572
   PubMed Web of Science ®Google Scholar
• YangSW, QuYH, ZhangH, et al. Hypoglycemic effects of polysaccharides from Gomphidiaceae rutilus fruiting bodies and their mechanisms. Food Funct. 2020;11(1):424–434. doi:10.1039/c9fo02283j31828269
   PubMed Web of Science ®Google Scholar
• NakayamaM, BeilkeJN, JasinskiJM, et al. Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity. J Clin Invest. 2007;117(7):1835–1843. doi:10.1172/JCI3136817607359
   PubMed Web of Science ®Google Scholar
• RoepBO, ArdenSD, de VriesRRP, HuttonJC. T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins. Nature. 1990;345(6276):632–634. doi:10.1038/345632a02190098
   PubMed Web of Science ®Google Scholar
• YoonJW, YoonCS, LimHW, et al. Control of autoimmune diabetes in NOD Mice by GAD expression or suppression in cells. Science. 1999;284(5417):1183–1187. doi:10.1126/science.284.5417.118310325232
   PubMed Web of Science ®Google Scholar
• LefterovaMI, HaakonssonAK, LazarMA, MandrupS. PPARγ and the global map of adipogenesis and beyond. Trends Endocrinol Metab. 2014;25(6):293–302. doi:10.1016/j.tem.2014.04.00124793638
   PubMed Web of Science ®Google Scholar
• WangS, DoughertyEJ, DannerRL. PPARγ signaling and emerging opportunities for improved therapeutics. Pharmacol Res. 2016;111:76–85. doi:10.1016/j.phrs.2016.02.02827268145
   PubMed Web of Science ®Google Scholar
• MalurA, McCoyAJ, ArceS, et al. Deletion of PPAR gamma in alveolar macrophages is associated with a Th-1 pulmonary inflammatory response. J Immunol. 2009;182(9):5816–5822. doi:10.4049/jimmunol.080350419380830
   PubMed Web of Science ®Google Scholar
• WohlfertEA, NicholsFC, NeviusE, ClarkRB. Peroxisome proliferator-activated receptor gamma (PPARgamma) and immunoregulation: enhancement of regulatory T cells through PPARgamma-dependent and -independent mechanisms. J Immunol. 2007;178(7):4129–4135. doi:10.4049/jimmunol.178.7.412917371968
   PubMed Web of Science ®Google Scholar
• LiR-J, QiuS-D, ChenH-X, TianH, WangH-X. The immunotherapeutic effects of Astragalus polysaccharide in type 1 diabetic mice. Biol Pharm Bull. 2007;30(3):470–476. doi:10.1248/bpb.30.47017329840
   PubMed Web of Science ®Google Scholar
• SaubermannLJ, NakajimaA, WadaK, et al. Peroxisome proliferator-activated receptor gamma agonist ligands stimulate a Th2 cytokine response and prevent acute colitis. Inflamm Bowel Dis. 2002;8(5):330–339. doi:10.1097/00054725-200209000-0000412479648
   PubMed Web of Science ®Google Scholar
• LenschowDJ, HeroldKC, RheeL, et al. CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. Immunity. 1996;5(3):285–293. doi:10.1016/S1074-7613(00)80323-48808683
   PubMed Web of Science ®Google Scholar
• WelchJS, RicoteM, AkiyamaTE, GonzalezFJ, GlassCK. PPARγ and PPARδ negatively regulate specific subsets of lipopolysaccharide and IFN-γ target genes in macrophages. Proc Natl Acad Sci U S A. 2003;100(11):6712. doi:10.1073/pnas.103178910012740443
   PubMed Web of Science ®Google Scholar
• CunardR, RicoteM, DiCampliD, et al. Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors. J Immunol. 2002;168(6):2795. doi:10.4049/jimmunol.168.6.279511884448
   PubMed Web of Science ®Google Scholar
• GorDO, RoseNR, GreenspanNS. TH1-TH2: a Procrustean paradigm. Nat Immunol. 2003;4(6):503–505. doi:10.1038/ni0603-50312774069
   PubMed Web of Science ®Google Scholar