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Original Research

Resveratrol Pretreatment Inhibits Myocardial Apoptosis in Rats Following Coronary Microembolization via Inducing the PI3K/Akt/GSK-3β Signaling Cascade

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Pages 3821-3834 | Published online: 07 Sep 2021

References

  • HeuschG, KleinbongardP, BoseD, et al. Coronary microembolization: from bedside to bench and back to bedside. Circulation. 2009;120(18):1822–1836. doi:10.1161/CIRCULATIONAHA.109.88878419884481
  • HeuschG, SkyschallyA, KleinbongardP. Coronary microembolization and microvascular dysfunction. Int J Cardiol. 2018;258:17–23. doi:10.1016/j.ijcard.2018.02.01029429637
  • ScarponeM, CenkoE, ManfriniO. Coronary no-reflow phenomenon in clinical practice. Curr Pharm Des. 2018;24(25):2927–2933. doi:10.2174/138161282466618070211253629962336
  • SkyschallyA, GresP, HoffmannS, et al. Bidirectional role of tumor necrosis factor-alpha in coronary microembolization: progressive contractile dysfunction versus delayed protection against infarction. Circ Res. 2007;100(1):140–146. doi:10.1161/01.RES.0000255031.15793.8617170366
  • JaffeR, CharronT, PuleyG, DickA, StraussBH. Microvascular obstruction and the no-reflow phenomenon after percutaneous coronary intervention. Circulation. 2008;117(24):3152–3156. doi:10.1161/CIRCULATIONAHA.107.74231218559715
  • LiuT, ZhouY, WangJY, et al. Coronary microembolization induces cardiomyocyte apoptosis in swine by activating the LOX-I-dependent mitochondrial pathway and caspase-8-dependent pathway. J Cardiovasc Pharmacol Ther. 2016;21(2):209–218. doi:10.1177/107424841559926526275408
  • ChenZW, QianJY, MaJY, et al. TNF-alpha-induced cardiomyocyte apoptosis contributes to cardiac dysfunction after coronary microembolization in mini-pigs. J Cell Mol Med. 2014;18(10):1953–1963. doi:10.1111/jcmm.1234225130514
  • KongB, QinZ, YeZ, YangX, LiL, SuQ. microRNA-26a-5p affects myocardial injury induced by coronary microembolization by modulating HMGA1. J Cell Biochem. 2019;120(6):10756–10766. doi:10.1002/jcb.2836730652345
  • ChenZQ, ZhouY, HuangJW, et al. Puerarin pretreatment attenuates cardiomyocyte apoptosis induced by coronary microembolization in rats by activating the PI3K/Akt/GSK-3beta signaling pathway. Korean J Physiol Pharmacol. 2021;25(2):147–157. doi:10.4196/kjpp.2021.25.2.14733602885
  • WicinskiM, SochaM, WalczakM, et al. Beneficial effects of resveratrol administration-focus on potential biochemical mechanisms in cardiovascular conditions. Nutrients. 2018;10(11):1813. doi:10.3390/nu10111813
  • YangY, WangX, ZhangL, AnH, ZaoZ. Inhibitory effects of resveratrol on platelet activation induced by thromboxane a(2) receptor agonist in human platelets. Am J Chin Med. 2011;39(1):145–159. doi:10.1142/S0192415X1100871321213405
  • AbbasAM. Cardioprotective effect of resveratrol analogue isorhapontigenin versus omega-3 fatty acids in isoproterenol-induced myocardial infarction in rats. J Physiol Biochem. 2016;72(3):469–484. doi:10.1007/s13105-016-0494-427193109
  • UngvariZ, BagiZ, FeherA, et al. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol. 2010;299(1):H18–24. doi:10.1152/ajpheart.00260.201020418481
  • XuK, LiuXF, KeZQ, YaoQ, GuoS, LiuC. Resveratrol modulates apoptosis and autophagy induced by high glucose and palmitate in cardiac cells. Cell Physiol Biochem. 2018;46(5):2031–2040. doi:10.1159/00048944229723857
  • MaoQ, LiangX, WuY, LuY. Resveratrol attenuates cardiomyocyte apoptosis in rats induced by coronary microembolization through SIRT1-mediated deacetylation of p53. J Cardiovasc Pharmacol Ther. 2019;24(6):551–558. doi:10.1177/107424841984591631046448
  • ZhangHH, WuQQ, WanZ, CaoY, ZengZ. Preconditioning but not postconditioning treatment with resveratrol substantially ameliorates post-resuscitation myocardial dysfunction through the PI3K/Akt signaling pathway. Mol Med Rep. 2019;20(2):1250–1258.31173195
  • WilsonDN, SchachtSE, Al-NakkashL, BabuJR, BroderickTL. Resveratrol prevents pulmonary trunk remodeling but not right ventricular hypertrophy in monocrotaline-induced pulmonary hypertension. Pathophysiology. 2016;23(4):243–250. doi:10.1016/j.pathophys.2016.05.00427374951
  • KapetanovicIM, MuzzioM, HuangZ, ThompsonTN, McCormickDL. Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats. Cancer Chemother Pharmacol. 2011;68(3):593–601. doi:10.1007/s00280-010-1525-421116625
  • SuQ, LvX, SunY, YeZ, KongB, QinZ. Role of TLR4/MyD88/NF-kappaB signaling pathway in coronary microembolization-induced myocardial injury prevented and treated with nicorandil. Biomed Pharmacother. 2018;106:776–784. doi:10.1016/j.biopha.2018.07.01429990871
  • ZhuHH, WangXT, SunYH, et al. MicroRNA-486-5p targeting PTEN protects against coronary microembolization-induced cardiomyocyte apoptosis in rats by activating the PI3K/AKT pathway. Eur J Pharmacol. 2019;855:244–251. doi:10.1016/j.ejphar.2019.03.04531075240
  • ChenQF, WangW, HuangZ, et al. Role of high-mobility group B1 in myocardial injury induced by coronary microembolization in rats. J Cell Biochem. 2019;120(3):4238–4247. doi:10.1002/jcb.2770930269353
  • BoseD, von BirgelenC, ZhouXY, et al. Impact of atherosclerotic plaque composition on coronary microembolization during percutaneous coronary interventions. Basic Res Cardiol. 2008;103(6):587–597. doi:10.1007/s00395-008-0745-918787802
  • DorgeH, NeumannT, BehrendsM, et al. Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation. Am J Physiol Heart Circ Physiol. 2000;279(6):H2587–H2592. doi:10.1152/ajpheart.2000.279.6.H258711087208
  • SunYH, SuQ, LiL, WangXT, LuYX, LiangJB. Expression of p53 in myocardium following coronary microembolization in rats and its significance. J Geriatr Cardiol. 2017;14(5):292–300.28630604
  • SuQ, LvX, SunY, YangH, YeZ, LiL. Role of high mobility group A1/nuclear factor-kappa B signaling in coronary microembolization-induced myocardial injury. Biomed Pharmacother. 2018;105:1164–1171. doi:10.1016/j.biopha.2018.06.09830021353
  • NakataR, TakahashiS, InoueH. Recent advances in the study on resveratrol. Biol Pharm Bull. 2012;35(3):273–279. doi:10.1248/bpb.35.27322382311
  • ChenCJ, YuW, FuYC, WangX, LiJL, WangW. Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway. Biochem Biophys Res Commun. 2009;378(3):389–393. doi:10.1016/j.bbrc.2008.11.11019059213
  • XuH, ChengJ, WangX, et al. Resveratrol pretreatment alleviates myocardial ischemia/reperfusion injury by inhibiting STIM1-mediated intracellular calcium accumulation. J Physiol Biochem. 2019;75(4):607–618. doi:10.1007/s13105-019-00704-531786730
  • FrankeTF, HornikCP, SegevL, ShostakGA, SugimotoC. PI3K/Akt and apoptosis: size matters. Oncogene. 2003;22(56):8983–8998. doi:10.1038/sj.onc.120711514663477
  • TsukaharaS, YamamotoS, AhmedS, et al. Inhalation of low-level formaldehyde increases the Bcl-2/Bax expression ratio in the hippocampus of immunologically sensitized mice. Neuroimmunomodulation. 2006;13(2):63–68. doi:10.1159/00009482916888403
  • ZhangX, ShiM, YeR, et al. Ginsenoside Rd attenuates tau protein phosphorylation via the PI3K/AKT/GSK-3beta pathway after transient forebrain ischemia. Neurochem Res. 2014;39(7):1363–1373. doi:10.1007/s11064-014-1321-324792734
  • ParkSJ, JinML, AnHK, et al. Emodin induces neurite outgrowth through PI3K/Akt/GSK-3β-mediated signaling pathways in Neuro2a cells. Neurosci Lett. 2015;588:101–107. doi:10.1016/j.neulet.2015.01.00125562207
  • ZhengT, YangXY, WuD, et al. Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3 pathway. Brit J Pharmacol. 2015;172(13):3284–3301. doi:10.1111/bph.1312025754463
  • ZhangYN, ZhangZ, WangHT, et al. Neuroprotective effect of ginsenoside Rg1 prevents cognitive impairment induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3 pathway. Mol Med Rep. 2016;14(3):2778–2784. doi:10.3892/mmr.2016.555627485139
  • WeiDJ, XuHJ, GaiXD, JiangY. Astragaloside IV alleviates myocardial ischemia-reperfusion injury in rats through regulating PI3K/AKT/GSK-3 beta signaling pathways. Acta Cir Bras. 2019;34(7). doi:10.1590/s0102-865020190070000008
  • ZhangL, GuoZ, WangY, GengJ, HanS. The protective effect of kaempferol on heart via the regulation of Nrf2, NF-κβ, and PI3K/Akt/GSK-3β signaling pathways in isoproterenol-induced heart failure in diabetic rats. Drug Dev Res. 2019;80(3):294–309. doi:10.1002/ddr.2149530864233