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Original Research

A Promising Single Oral Disintegrating Tablet for Co-Delivery of Pitavastatin Calcium and Lornoxicam Using Co-Processed Excipients: Formulation, Characterization and Pharmacokinetic Study

ORCID Icon, , , & ORCID Icon
Pages 4229-4242 | Published online: 07 Oct 2021

References

  • DasariN, MaruvajalaV. Preparation and evaluation of fast dissolving tablets of pitavastatin by 32 full factorial design. Int J App Pharm. 2020;12(1):108–114.
  • NiranjaniS, VenkatachalamK. Method development and validation of pitavastatin calcium and its degradation behavior under varied stress conditions by UV spectrophotometric methods. Dhaka Univ J Pharm Sci. 2019;18(2):159–169. doi:10.3329/dujps.v18i2.43258
  • KumarP, ManglaB, SinghS. Pitavastatin: a potent drug pitavastatin: a potent drug. Int J Pharma Res Health Sci. 2018;6(1):2070–2074.
  • WardNC, WattsGF, EckelRH. Statin toxicity: mechanistic insights and clinical implications. Circ Res. 2019;124(2):328–350. doi:10.1161/CIRCRESAHA.118.31278230653440
  • HattKM, VijapuraA, MaitinIB, CruzE. Safety Considerations in Prescription of NSAIDs for Musculoskeletal Pain: a Narrative Review. PM R. 2018;10(12):1404–1411. doi:10.1016/j.pmrj.2018.06.01129964214
  • TayalS. The role of lornoxicam in pain and inflammation: a review. Curr Res Pharm Sci. 2012;01:1–4.
  • RaiPK, ModiK. Orally disintegrating tablets: a novel approach for medication. Int j Med Health Res. 2019;5(1):84–91.
  • PinhoLA, TemerAC, RibeiroC, Sá-BarretoLL, Cunha-FilhoMSS. the popularization of orodispersible tablets in the pharmaceutical market. Infarma Ciências Farm. 2018;30(2):77–84. doi:10.14450/2318-9312.v30.e2.a2018.pp77-84
  • TawfeekHM, FaisalW, SolimanGM. Enalapril maleate orally disintegrating tablets: tableting and in vivo evaluation in hypertensive rats. Pharm Dev Technol. 2018;23(5):496–503. doi:10.1080/10837450.2017.132931828489472
  • El-NabarawiMA, TeaimaMH, HamidMMA, ShomanNA, MohamedAI, El-SaharA. Formulation, evaluation and antioxidant activity of caffeine fast melt tablets. Res J Pharm Technol. 2018;11(7):3131–3138.
  • El-NabarawiMA, El-MonemRAA; Inas Essam Ibrahim Al-Samadi. Effect of co-process excipients in formulation of ODTs using a model drug. Int J Pharm Sci Res. 2019;10(5):2172–2181.
  • ElmeshadAN, Abdel-HaleemKM, GawadNAA, El-nabarawiMA, ShetaNM. Core in Cup Ethylmorphine Hydrochloride Tablet for Dual Fast and Sustained Pain Relief: formulation, Characterization, and Pharmacokinetic Study. AAPS PharmSciTech. 2020;21(7):1–11. doi:10.1208/s12249-020-01759-0
  • Karsono TanuwijayaJ, FatmaD. Formulation of ibuprofen orally disintegrating tablets (ODTs) by Lyophilization method using gelatin and mannitol. Int J PharmTech Res. 2014;6(3):996–1002.
  • PhulzalkeSB, KateBA, BagadeMY, SheteRV. Formulation development and evaluation of orodispersible tablets of quetiapine fumarate by sublimation method. Asian J Biomed Pharm Sci. 2016;6(57):22–31.
  • PatraCN, KumarAB, PanditHK, SinghSP, DeviMV. Design and evaluation of sustained release bilayer tablets of propranolol hydrochloride. Acta Pharm. 2007;57:479–489. doi:10.2478/v10007-007-0038-018165191
  • PandaN, ReddyAV, ReddyGVS, SultanaA. Formulation design and in vitro evaluation of bilayer sustained release matrix tablets of doxofylline. Int J Pharm Sci. 2015;7(10):74–83.
  • AherSS, SaudagarRB, ShindeMS. Review: fast dissolving tablet. Int J Curr Pharm Res. 2018;10(2):5–12. doi:10.22159/ijcpr.2018v10i2.25876
  • PandaS, HemalathaN, ShankarPU, BaratamSR. Formulation and evaluation of orodispersible tablets (ODTS) of diclofenac sodium by using superdisintegrant from natural origin. Int J App Pharm. 2019;11(6):190–197. doi:10.22159/ijap.2019v11i6.33480
  • MoqbelHA, ElMeshadAN, El-NabarawiMA. A pharmaceutical study on chlorzoxazone orodispersible tablets: formulation, in-vitro and in-vivo evaluation. Drug Deliv. 2016;23(8):2998–3007. doi:10.3109/10717544.2016.113834026828616
  • MoutasimMY, ElMeshadAN, El-NabarawiMA. A pharmaceutical study on lornoxicam fast disintegrating tablets: formulation and in vitro and in vivo evaluation. Drug Deliv Transl Res. 2017;7(3):450–459. doi:10.1007/s13346-017-0367-628283842
  • ShuklaV, ManviFV. Effect of Kollidon Cl on release behavior of isoniazid and rifampicin combination dispersible tablets for oral treatment of tuberculosis. Int J Drug Dev Res. 2010;2(4):892–906.
  • El-NabarawiMA, MakkyAM, El-SetouhyDA, Abd-ElmoniemR, AminMG, JastiBA. Fabrication, evaluation and preliminary clinical study of bi-layer orobuccal devices containing ketorolac tromethamine and chlorhexidine HCL for treatment of oral inflammation. Int J Pharm Sci. 2014;6(2):851–857.
  • MukhtarRYA, ReidJ, RecklessJPD. Statin-induced myositis: a commonly encountered or rare side effect? Drug Focus. 2005;59(2):239–252.
  • AnsariJA, BhandariU, HaqueSE, PillaiKK. Enhancement of antioxidant defense mechanism by pitavastatin and rosuvastatin on obesity-induced oxidative stress in Wistar rats. Toxicol Mech Methods. 2012;22(1):67–73. doi:10.3109/15376516.2011.60339121859367
  • LiF, SongS, GuoY, et al. Preparation and pharmacokinetics evaluation of oral self-emulsifying system for poorly water-soluble drug Lornoxicam. Drug Deliv. 2015;22(4):487–498. doi:10.3109/10717544.2014.88561524524289
  • HabibBA, Abd El-SamiaeAS, El-HoussienyBM, TagR. Formulation, characterization, optimization, and in-vivo performance of febuxostat self-nano-emulsifying system loaded sublingual films. Drug Deliv. 2021;28(1):1321–1333. doi:10.1080/10717544.2021.192724734176376
  • ZimmermannM. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 1983;16(2):109–110. doi:10.1016/0304-3959(83)90201-46877845
  • BaeJ, JohnstonTA, ChaiittiananR, SutthanutK, JayM, MarsonL. Characterization and in vivo efficacy of a heptapeptide ODT formulation for the treatment of neurogenic bladder dysfunction. Int J Pharm. 2018;536(1):397–404. doi:10.1016/j.ijpharm.2017.11.03629195918
  • CocchettoDM, BjornssonTD. Methods for vascular access and collection of body fluids from the laboratory rat. J Pharm Sci. 1983;72(5):465–492.6345750
  • AbdelmonemRA, Abd El GalilRM, El-SetouhyDA, El-MiligiMF, El-NabarawiMA. Dissolution enhancement and formulation of film coated tablets of lornoxicam by phase transition method: in vitro and in vivo evaluation. Int J App Pharm. 2020;12(3):74–85. doi:10.22159/ijap.2020v12i3.36867
  • ZaidAN, MousaA, JaradatN, BustamiR. Lornoxicam Immediate-Release Tablets: formulation and Bioequivalence Study in Healthy Mediterranean Volunteers Using a Validated LC-MS/MS Method. Clin Pharmacol Drug Dev. 2017;6(6):564–569. doi:10.1002/cpdd.33328176487
  • YinT, LiuQ, ZhaoH, et al. LC-MS/MS assay for pitavastatin in human plasma and subsequent application to a clinical study in healthy Chinese volunteers. Asian J Pharm Sci. 2014;9(6):348–355. doi:10.1016/j.ajps.2014.07.002
  • GuptaA, JainAK, PatelNN, ParmarJ, ChaudharyR. Formulation & evaluation of orodispersible tablets of diazepam. Pharm Res. 2002;7(2):23–32.
  • DaveV, YadavRB, AhujaR, YadavS. Formulation design and optimization of novel fast dissolving tablet of chlorpheniramine maleate by using lyophilization techniques. Bull Fac Pharmacy Cairo Univ. 2017;5(1):31–39. doi:10.1016/j.bfopcu.2016.12.001
  • TayelSA, El NabarawiMA, AminMM, AbouGhalyMHH. Comparative Study Between Different Ready-Made Orally Disintegrating Platforms for the Formulation of Sumatriptan Succinate Sublingual Tablets. AAPS PharmSciTech. 2017;18(2):410–423. doi:10.1208/s12249-016-0517-z27038484
  • AhmedIS, ShammaRN, ShoukriRA. Development and optimization of lyophilized orally disintegrating tablets using factorial design. Pharm Dev Technol. 2013;18(4):935–943. doi:10.3109/10837450.2011.61954322107175