260
Views
9
CrossRef citations to date
0
Altmetric
Review

Ulipristal acetate: a novel pharmacological approach for the treatment of uterine fibroids

, , , , &
Pages 285-292 | Published online: 20 Feb 2014

References

  • Okolo S Incidence, aetiology and epidemiology of uterine fibroids Best Pract Res Clin Obstet Gynaecol 2008 22 4 571 588
  • Marshall LM Spiegelman D Barbieri RL Variation in the incidence of uterine leiomyoma among premenopausal women by age and race Obstet Gynecol 1997 90 6 967 973 9397113
  • Rein MS Barbieri RL Friedman AJ Progesterone: a critical role in the pathogenesis of uterine myomas Am J Obstet Gynecol 1995 172 1 Pt 1 14 18 7847524
  • Andersen J Growth factors and cytokines in uterine leiomyomas Semin Reprod Endocrinol 1996 14 269 282
  • Fields KR Neinstein LS Uterine myomas in adolescents: case reports and a review of the literature J Pediatr Adolesc Gynecol 1996 9 4 195 198
  • Zimmermann A Bernuit D Gerlinger C Schaefers M Geppert K Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women BMC Womens Health 2012 12 6
  • Ke LQ Yang K Li J Li CM Danazol for uterine fibroids [review] Cochrane Database Syst Rev 2009 3 CD007692
  • Murat Naki M Tekcan C Ozcan N Cebi M Levonorgestrel-releasing intrauterine device insertion ameliorates leiomyoma-dependent menorrhagia among women of reproductive age without a significant regression in the uterine and leiomyoma volumes Fertil Steril 2010 94 1 371 374
  • Zapata LB Whiteman MK Tepper NK Jamieson DJ Marchbanks PA Curtis KM Intrauterine device use among women with uterine fibroids: a systematic review Contraception 2010 82 1 41 55 20682142
  • Ikomi A Pepra EF Efficacy of the levonorgestrel intrauterine system in treating menorrhagia: actualities and ambiguities J Fam Plann Reprod Health Care 2002 28 2 99 100 12396783
  • Lethaby AE Vollenhoven BJ An evidence-based approach to hormonal therapies for premenopausal women with fibroids Best Pract Res Clin Obstet Gynaecol 2008 22 2 307 331 17905660
  • Stovall TG Muneyyirci-Delale O Summitt RL Scialli AR GnRH agonist and iron versus placebo and iron in the anemic patient before surgery for leiomyomas: a randomized controlled trial. Leuprolide Acetate Study Group Obstet Gynecol 1995 86 1 65 71
  • Lethaby A Vollenhoven B Sowter MC Preoperative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids [review] Cochrane Database Syst Rev 2001 2 CD000547 11405968
  • Varelas FK Papanicolaou AN Vavatsi-Christaki N Makedos GA Vlassis GD The effect of anastrazole on symptomatic uterine leiomyomata Obstet Gynecol 2007 110 3 643 649
  • Parsanezhad ME Azmoon M Alborzi S A randomized, controlled clinical trial comparing the effects of aromatase inhibitor (letrozole) and gonadotropin-releasing hormone agonist (triptorelin) on uterine leiomyoma volume and hormonal status Fertil Steril 2010 93 1 192 198
  • Tamaya T Fujimoto J Okada H Comparison of cellular levels of steroid receptors in uterine leiomyoma and myometrium Acta Obstet Gynecol Scand 1985 64 4 307 309 4024879
  • Maruo T Matsuo H Samoto T Effects of progesterone on uterine leiomyoma growth and apoptosis Steroids 2000 65 10–11 585 592
  • Chwalisz K Perez MC Demanno D Winkel C Schubert G Elger W Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis Endocr Rev 2005 26 3 423 438
  • Chabbert-Buffet N Meduri G Bouchard P Spitz IM Selective progesterone receptor modulators and progesterone antagonists: mechanisms of action and clinical applications Hum Reprod Update 2005 11 3 293 307
  • Spitz IM Clinical utility of progesterone receptor modulators and their effect on the endometrium Curr Opin Obstet Gynecol 2009 21 4 318 324 19602929
  • Talaulikar VS Manyonda I Progesterone and progesterone receptor modulators in the management of symptomatic uterine fibroids Eur J Obstet Gynecol Reprod Biol 2012 165 2 135 140
  • Donnez J Tatarchuk TF Bouchard P PEARL I Study Group Ulipristal acetate versus placebo for fibroid treatment before surgery N Engl J Med 2012 366 5 409 420 22296075
  • Donnez J Tomaszewski J Vázquez F PEARL II Study Group Ulipristal acetate versus leuprolide acetate for uterine fibroids N Engl J Med 2012 366 5 421 432
  • Higham JM O’Brien PM Shaw RW Assessment of menstrual blood loss using a pictorial chart Br J Obstet Gynaecol 1990 97 8 734 739 2400752
  • Mutter GL Bergeron C Deligdisch L The spectrum of endometrial pathology induced by progesterone receptor modulators Mod Pathol 2008 21 5 591 598
  • Williams AR Bergeron C Barlow DH Ferenczy A Endometrial morphology after treatment of uterine fibroids with the selective progesterone receptor modulator, ulipristal acetate Int J Gynecol Pathol 2012 31 6 556 569 23018219
  • Bläuer M Heinonen PK Rovio P Ylikomi T Effects of tamoxifen and raloxifene on normal human endometrial cells in an organotypic in vitro model Eur J Pharmacol 2008 592 1–3 13 18
  • Noyes RW Hertig AT Rock J Dating the endometrial biopsy Am J Obstet Gynecol 1975 122 2 262 263
  • Hendrickson MR Longacre TA Keempson RL The uterine corpus Sternberg SS Diagnostic Surgical Pathology Philadelphia Lippincott 1999 2203 2204
  • Biron-Shental T Tepper R Fishman A Shapira J Cohen I Recurrent endometrial polyps in postmenopausal breast cancer patients on tamoxifen Gynecol Oncol 2003 90 2 382 386 12893204
  • Frederick J Hardie M Reid M Fletcher H Wynter S Frederick C Operative morbidity and reproductive outcome in secondary myomectomy: a prospective cohort study Hum Reprod 2002 17 11 2967 2971 12407058
  • Friedman AJ Lobel SM Rein MS Barbieri RL Efficacy and safety considerations in women with uterine leiomyomas treated with gonadotropin-releasing hormone agonists: the estrogen threshold hypothesis Am J Obstet Gynecol 1990 163 4 Pt 1 1114 1119
  • Brosens IA Variable response of uterine leiomyomas after GnRH agonist therapy Fertil Steril 1997 68 5 948 949 9389836
  • Maheux R Guilloteau C Lemay A Bastide A Fazekas AT Regression of leiomyomata uteri following hypoestrogenism induced by repetitive luteinizing hormone-releasing hormone agonist treatment: preliminary report Fertil Steril 1984 42 4 644 646