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Original Research

Inhibition of B7-1 (CD80) by RhuDex® reduces lipopolysaccharide-mediated inflammation in human atherosclerotic lesions

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Pages 447-457 | Published online: 12 May 2014

References

  • Ross R Atherosclerosis – an inflammatory disease N Engl J Med 1999 340 2 115 126 9887164
  • Galkina E Ley K Immune and inflammatory mechanisms of atherosclerosis (*) Annu Rev Immunol 2009 27 165 197 19302038
  • Virmani R Kolodgie FD Burke AP Farb A Schwartz SM Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions Arterioscler Thromb Vasc Biol 2000 20 5 1262 1275 10807742
  • Erbel C Sato K Meyer FB Functional profile of activated dendritic cells in unstable atherosclerotic plaque Basic Res Cardiol 2007 102 2 123 132 17136419
  • Wick G Knoflach M Xu Q Autoimmune and inflammatory mechanisms in atherosclerosis Annu Rev Immunol 2004 22 361 403 15032582
  • Sharpe AH Freeman GJ The B7-CD28 superfamily Nat Rev Immunol 2002 2 2 116 126 11910893
  • Freeman GJ Gribben JG Boussiotis VA Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation Science 1993 262 5135 909 911 7694363
  • Hathcock KS Laszlo G Pucillo C Linsley P Hodes RJ Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function J Exp Med 1994 180 2 631 640 7519245
  • Boulougouris G McLeod JD Patel YI Ellwood CN Walker LS Sansom DM Positive and negative regulation of human T cell activation mediated by the CTLA-4/CD28 ligand CD80 J Immunol 1998 161 8 3919 3924 9780158
  • Inobe M Aoki N Linsley PS The role of the B7-1a molecule, an alternatively spliced form of murine B7-1 (CD80), on T cell activation J Immunol 1996 157 2 582 588 8752905
  • Chai JG Vendetti S Amofah E Dyson J Lechler R CD152 ligation by CD80 on T cells is required for the induction of unresponsiveness by costimulation-deficient antigen presentation J Immunol 2000 165 6 3037 3042 10975813
  • Lanier LL O’Fallon S Somoza C CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL J Immunol 1995 154 1 97 105 7527824
  • Gotsman I Sharpe AH Lichtman AH T-cell costimulation and coinhibition in atherosclerosis Circ Res 2008 103 11 1220 1231 19028921
  • Buono C Pang H Uchida Y Libby P Sharpe AH Lichtman AH B7-1/B7-2 costimulation regulates plaque antigen-specific T-cell responses and atherogenesis in low-density lipoprotein receptor-deficient mice Circulation 2004 109 16 2009 2015 15096453
  • Ait-Oufella H Salomon BL Potteaux S Natural regulatory T cells control the development of atherosclerosis in mice Nat Med 2006 12 2 178 180 16462800
  • de Boer OJ Hirsch F van der Wal AC van der Loos CM Das PK Becker AE Costimulatory molecules in human atherosclerotic plaques: an indication of antigen specific T lymphocyte activation Atherosclerosis 1997 133 2 227 234 9298683
  • Haanstra KG Endell J Estévâo D Kondova I Jonker M Blocking T cell co-stimulation using a CD80 blocking small molecule reduces delayed type hypersensitivity responses in rhesus monkeys Clin Exp Immunol 2009 158 1 91 98 19737235
  • Stary HC Natural history and histological classification of atherosclerotic lesions: an update Arterioscler Thromb Vasc Biol 2000 20 5 1177 1178 10807728
  • Gleissner CA Shaked I Erbel C Böckler D Katus HA Ley K CXCL4 downregulates the atheroprotective hemoglobin receptor CD163 in human macrophages Circ Res 2010 106 1 203 211 19910578
  • Erbel C Chen L Bea F Inhibition of IL-17A attenuates atherosclerotic lesion development in apoE-deficient mice J Immunol 2009 183 12 8167 8175 20007582
  • Stoll G Bendszus M Inflammation and atherosclerosis: novel insights into plaque formation and destabilization Stroke 2006 37 7 1923 1932 16741184
  • Niessner A Shin MS Pryshchep O Goronzy JJ Chaikof EL Weyand CM Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque Circulation 2007 116 18 2043 2052 17938289
  • Lu YC Yeh WC Ohashi PS LPS/TLR4 signal transduction pathway Cytokine 2008 42 2 145 151 18304834
  • Edfeldt K Swedenborg J Hansson GK Yan ZQ Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation Circulation 2002 105 10 1158 1161 11889007
  • Monaco C The tolls and dangers of atherosclerotic disease Curr Pharm Biotechnol 2012 13 1 77 87 21470159
  • Lim W Gee K Mishra S Kumar A Regulation of B7.1 costimulatory molecule is mediated by the IFN regulatory factor-7 through the activation of JNK in lipopolysaccharide-stimulated human monocytic cells J Immunol 2005 175 9 5690 5700 16237059
  • Curiel RE Garcia CS Rottschafer S Bosco MC Espinoza-Delgado I Enhanced B7-2 gene expression by interferon-gamma in human monocytic cells is controlled through transcriptional and posttranscriptional mechanisms Blood 1999 94 5 1782 1789 10477704
  • Creery WD Diaz-Mitoma F Filion L Kumar A Differential modulation of B7-1 and B7-2 isoform expression on human monocytes by cytokines which influence the development of T helper cell phenotype Eur J Immunol 1996 26 6 1273 1277 8647204
  • Mattern T Flad HD Brade L Rietschel ET Ulmer AJ Stimulation of human T lymphocytes by LPS is MHC unrestricted, but strongly dependent on B7 interactions J Immunol 1998 160 7 3412 3418 9531301
  • Andersson J Libby P Hansson GK Adaptive immunity and atherosclerosis Clin Immunol 2010 134 1 33 46 19635683
  • Blankenberg S Barbaux S Tiret L Adhesion molecules and atherosclerosis Atherosclerosis 2003 170 2 191 203 14612198
  • Zhang X Niessner A Nakajima T Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque Circ Res 2006 98 4 524 531 16424368
  • Harvey EJ Ramji DP Interferon-gamma and atherosclerosis: pro- or anti-atherogenic? Cardiovasc Res 2005 67 1 11 20 15907820
  • Luyendyk JP Piper JD Tencati M A novel class of antioxidants inhibit LPS induction of tissue factor by selective inhibition of the activation of ASK1 and MAP kinases Arterioscler Thromb Vasc Biol 2007 27 8 1857 1863 17561491
  • Rus HG Vlaicu R Niculescu F Interleukin-6 and interleukin-8 protein and gene expression in human arterial atherosclerotic wall Atherosclerosis 1996 127 2 263 271 9125317
  • O’Garra A Vieira P T(H)1 cells control themselves by producing interleukin-10 Nat Rev Immunol 2007 7 6 425 428 17525751
  • Mosser DM Zhang X Interleukin-10: new perspectives on an old cytokine Immunol Rev 2008 226 205 218 19161426
  • Gu L Okada Y Clinton SK Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice Mol Cell 1998 2 2 275 281 9734366
  • DeGraba TJ Expression of inflammatory mediators and adhesion molecules in human atherosclerotic plaque Neurology 1997 49 5 Suppl 4 S15 S19 9371143
  • Onishi Y Fehervari Z Yamaguchi T Sakaguchi S Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation Proc Natl Acad Sci U S A 2008 105 29 10113 10118 18635688
  • Couper KN Blount DG Riley EM IL-10: the master regulator of immunity to infection J Immunol 2008 180 9 5771 5777 18424693
  • Cao S Zhang X Edwards JP Mosser DM NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages J Biol Chem 2006 281 36 26041 26050 16835236
  • Zhang X Edwards JP Mosser DM Dynamic and transient remodeling of the macrophage IL-10 promoter during transcription J Immunol 2006 177 2 1282 1288 16818788
  • Hu X Ivashkiv LB Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases Immunity 2009 31 4 539 550 19833085
  • Triantafilou M Triantafilou K Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster Trends Immunol 2002 23 6 301 304 12072369
  • Dobrovolskaia MA Vogel SN Toll receptors, CD14, and macrophage activation and deactivation by LPS Microbes Infect 2002 4 9 903 914 12106783
  • Oberbach A Schlichting N Blüher M Palmitate induced IL-6 and MCP-1 expression in human bladder smooth muscle cells provides a link between diabetes and urinary tract infections PLoS One 2010 5 5 e10882 20526368
  • Kogut MH Genovese KJ He H Kaiser P Flagellin and lipopolysaccharide up-regulation of IL-6 and CXCLi2 gene expression in chicken heterophils is mediated by ERK1/2-dependent activation of AP-1 and NF-kappaB signaling pathways Innate Immun 2008 14 4 213 222 18669607
  • Nakahira M Ahn HJ Park WR Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1 J Immunol 2002 168 3 1146 1153 11801649