135
Views
0
CrossRef citations to date
0
Altmetric
Original Research

Cytoprotective effect of selective small-molecule caspase inhibitors against staurosporine-induced apoptosis

, , &
Pages 583-600 | Published online: 24 May 2014

References

  • Pop C Salvesen GS Human caspases: activation, specificity, and regulation J Biol Chem 2009 284 33 21777 21781 19473994
  • Cohen GM Caspases: the executioners of apoptosis Biochem J 1997 326 Pt 1 1 16 9337844
  • Nicholson DW Thornberry NA Caspases: killer proteases Trends Biochem Sci 1997 22 8 299 306 9270303
  • Salvesen GS Dixit VM Caspases: intracellular signaling by proteolysis Cell 1997 91 4 443 446 9390553
  • Nagata S Apoptosis by death factor Cell 1997 88 3 355 365 9039262
  • Green DR Reed JC Mitochondria and apoptosis Science 1998 281 5381 1309 1312 9721092
  • Susin SA Lorenzo HK Zamzami N Molecular characterization of mitochondrial apoptosis-inducing factor Nature 1999 397 6718 441 446 9989411
  • McBride CB McPhail LT Vanderluit JL Tetzlaff W Steeves JD Caspase inhibition attenuates transection-induced oligodendrocyte apoptosis in the developing chick spinal cord Mol Cell Neurosci 2003 23 3 383 397 12837623
  • Papaconstantinou HT Xie C Zhang W The role of caspases in methotrexate-induced gastrointestinal toxicity Surgery 2001 130 5 859 865 11685196
  • Lee ER Kim JH Choi HY Jeon K Cho SG Cytoprotective effect of eriodictyol in UV-irradiated keratinocytes via phosphatase-dependent modulation of both the p38 MAPK and Akt signaling pathways Cell Physiol Biochem 2011 27 5 513 524 21691069
  • Park K Lee JH Protective effects of resveratrol on UVB-irradiated HaCaT cells through attenuation of the caspase pathway Oncol Rep 2008 19 2 413 417 18202789
  • Pauloin T Dutot M Joly F Warnet JM Rat P High molecular weight hyaluronan decreases UVB-induced apoptosis and inflammation in human epithelial corneal cells Mol Vis 2009 15 577 583 19325714
  • Rass K Reichrath J UV damage and DNA repair in malignant melanoma and nonmelanoma skin cancer Adv Exp Med Biol 2008 624 162 178 18348455
  • Smaili S Hirata H Ureshino R Calcium and cell death signaling in neurodegeneration and aging An Acad Bras Cienc 2009 81 3 467 475 19722016
  • GeneChip®expression analysis: data analysis fundamentals [technical manual] Sanra Clara, CA Affymetrix Inc 2004
  • Zhang JH Chung TD Oldenburg KR A simple statistical parameter for use in evaluation and validation of high throughput screening assays J Biomol Screen 1999 4 2 67 73 10838414
  • Okun I Malarchuk S Dubrovskaya E Screening for caspase-3 inhibitors: effect of a reducing agent on identified hit chemotypes J Biomol Screen 2006 11 6 694 703 16844966
  • Tamaoki T Nomoto H Takahashi I Kato Y Morimoto M Tomita F Staurosporine, a potent inhibitor of phospholipid/Ca++ dependent protein kinase Biochem Biophys Res Commun 1986 135 2 397 402 3457562
  • Rüegg UT Burgess GM Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases Trends Pharmacol Sci 1989 10 6 218 220 2672462
  • Belmokhtar CA Torriglia A Counis MF Courtois Y Jacquemin-Sablon A Ségal-Bendirdjian E Nuclear translocation of a leukocyte elastase Inhibitor/Elastase complex during staurosporine-induced apoptosis: role in the generation of nuclear L-DNase II activity Exp Cell Res 2000 254 1 99 109 10623470
  • Yuste VJ Sánchez-López I Solé C The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis J Biol Chem 2005 280 42 35670 35683 16049016
  • Smaili SS Hsu YT Sanders KM Russell JT Youle RJ Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential Cell Death Differ 2001 8 9 909 920 11526446
  • Petit PX Lecoeur H Zorn E Dauguet C Mignotte B Gougeon ML Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis J Cell Biol 1995 130 1 157 167 7790370
  • Zamzami N Marchetti P Castedo M Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death J Exp Med 1995 182 2 367 377 7629499
  • Wang X The expanding role of mitochondria in apoptosis Genes Dev 2001 15 22 2922 2933 11711427
  • Karachitos A García Del Pozo JS de Groot PW Kmita H Jordán J Minocycline mediated mitochondrial cytoprotection: premises for therapy of cerebrovascular and neurodegenerative diseases Curr Drug Targets 2013 14 1 47 55 23170796
  • Brenner C Ventura-Clapier R Jacotot E Mitochondria and cytoprotection Biochem Res Int 2012 2012 351264 22953062
  • Armstrong JS The role of the mitochondrial permeability transition in cell death Mitochondrion 2006 6 5 225 234 16935572
  • Galluzzi L Morselli E Kepp O Kroemer G Targeting post-mitochondrial effectors of apoptosis for neuroprotection Biochim Biophys Acta 2009 1787 5 402 413 18848916
  • Kristián T Metabolic stages, mitochondria and calcium in hypoxic/ischemic brain damage Cell Calcium 2004 36 3–4 221 233 15261478
  • Kumar P Coltas IK Kumar B Chepeha DB Bradford CR Polverini PJ Bcl-2 protects endothelial cells against gamma-radiation via a Raf-MEK-ERK-survivin signaling pathway that is independent of cytochrome c release Cancer Res 2007 67 3 1193 1202 17283155
  • Hoglen NC Chen LS Fisher CD Hirakawa BP Groessl T Contreras PC Characterization of IDN-6556 (3-[2-(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino]-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid): a liver-targeted caspase inhibitor J Pharmacol Exp Ther 2004 309 2 634 640 14742742
  • Weber P Wang P Maddens S VX-166: a novel potent small molecule caspase inhibitor as a potential therapy for sepsis Crit Care 2009 13 5 R146 19740426
  • Méthot N Huang J Coulombe N Differential efficacy of caspase inhibitors on apoptosis markers during sepsis in rats and implication for fractional inhibition requirements for therapeutics J Exp Med 2004 199 2 199 207 14718517
  • Kim KW Moretti L Lu B M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models PLoS One 2008 3 5 e2275 18509530
  • Callus BA Vaux DL Caspase inhibitors: viral, cellular and chemical Cell Death Differ 2007 14 1 73 78 16946729
  • Hyman BT Yuan J Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology Nat Rev Neurosci 2012 13 6 395 406 22595785