P-glycoprotein- and organic anion-transporting polypeptide-mediated transport of periplocin may lead to drug–herb/drug–drug interactions

References

• Zhang J Shan BE Liu GS Zhao XT Chen SH Anti-tumor activity of extract from Periploca sepium Bge Teratog Carcinog Mutagen 2006 18 2 108 111
   Google Scholar
• Li YH Gao XM Zhang BL Xu Q Liu H Pan GX Effect of the Chinese medicine xiangjiapi on cardiac function of isolated hearts J Liaoning Coll Tradit Chin Med 2005 7 4 396 397
   Google Scholar
• Xu LQ Lu HZ Zhang YL Clinical observation on treatment of 147 cases of chronic congestive heart-failure by bei wujiapi mixture Yunnan J Tradit Chin Med Mater Med 1998 19 4 29 31
   Google Scholar
• Egawa K Kurihara Y Ito T Matsumoto M Nose K Induction of p16 INK4a transcription and of cellular senescence by aclacinomycin-derivatives and cardiac glycosides Biol Pharm Bull 2002 25 4 461 465 11995925
   PubMed Web of Science ®Google Scholar
• Shugarts S Benet LZ The role of transporters in the pharmacokinetics of orally administered drugs Pharm Res 2009 26 9 2039 2054 19568696
   PubMed Web of Science ®Google Scholar
• Giacomini KM Huang SM Transporters in drug development and clinical pharmacology Clin Pharmacol Ther 2013 94 1 3 9 23778703
   PubMed Web of Science ®Google Scholar
• Ye L Yang X Yang Z The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells Toxicol Lett 2012 216 2–3 86 99 23200901
   PubMed Web of Science ®Google Scholar
• Liu CX Yi XL Si DY Xiao XF He X Li YZ Herb-drug interactions involving drug metabolizing enzymes and transporters Curr Drug Metab 2011 12 9 835 849 21619518
   PubMed Web of Science ®Google Scholar
• Wang Q Ren XL Wang Y Study on excretion of periplocin in rats J Tianjin Univ Tradit Chin Med 2008 27 1 29 32
   Google Scholar
• Shitara Y Sugiyama D Kusuhara H Comparative inhibitory effects of different compounds on rat Oatp1 (Slc21a1)-and Oatp2 (Slc21a5)-mediated transport Pharm Res 2002 19 2 147 153 11883641
   PubMed Web of Science ®Google Scholar
• Irvine JD Takahashi L Lockhart K MDCK (Madin-Darby canine kidney) cells: a tool for membrane permeability screening J Pharm Sci 1999 88 1 28 33 9874698
   PubMed Web of Science ®Google Scholar
• Mahar Dohan KM Humphreys JE Webster LO Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs J Pharmacol Exp Ther 2002 303 3 1029 1037 12438524
   PubMed Web of Science ®Google Scholar
• Keogh JP Kunta JR Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein Eur J Pharm Sci 2006 27 5 543 554 16406207
   PubMed Web of Science ®Google Scholar
• Dahan A Altman H Food-drug interaction: grapefruit juice augments drug bioavailability – mechanism, extent and relevance Eur J Clin Nutr 2004 58 1 1 9 14679360
   PubMed Web of Science ®Google Scholar
• Kim JS Mitchell S Kijek P Tsume Y Hilfinger J Amidon GL The suitability of an in situ perfusion model for permeability determinations: utility for BCS class I biowaiver requests Mol Pharm 2006 3 6 686 694 17140256
   PubMed Web of Science ®Google Scholar
• Dahan A Amidon GL MRP2 mediated drug drug interaction: indomethacin increases sulfasalazine absorption in the small intestine, potentially decreasing its colonic targeting Int J Pharm 2010 386 1 216 220 19944137
   PubMed Web of Science ®Google Scholar
• Rabba AK Si L Xue K Li M Li G In situ intestinal perfusion of irinotecan: application to P-gp mediated drug interaction and introduction of an improved HPLC assay J Pharm Pharm Sci 2011 14 2 138 147 21733405
   PubMed Web of Science ®Google Scholar
• Lindahl A Frid S Ungell AL Lennernäs H No evidence for the involvement of the multidrug resistance-associated protein and/or the monocarboxylic acid transporter in the intestinal transport of fluvastatin in rats AAPS PharmSci 2000 2 3 62 68
   Google Scholar
• Inoue H Yokota H Makino T Yuasa A Kato S Bisphenol A glucuronide, a major metabolite in rat bile after liver perfusion Drug Metab Dispos 2001 29 8 1084 1087 11454725
   PubMed Web of Science ®Google Scholar
• Lau YY Wu CY Okochi H Benet LZ Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay J Pharmacol Exp Ther 2004 308 3 1040 1045 14634033
   PubMed Web of Science ®Google Scholar
• Wen X Walle T Methylated flavonoids have greatly improved intestinal absorption and metabolic stability Drug Metab Dispos 2006 34 10 1786 1792 16868069
   PubMed Web of Science ®Google Scholar
• Fagerholm U Johansson M Lennernäs H Comparison between permeability coefficients in rat and human jejunum Pharm Res 1996 13 9 1336 1342 8893271
   PubMed Web of Science ®Google Scholar
• Noé B Hagenbuch B Stieger B Meier PJ Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain Proc Natl Acad Sci U S A 1997 94 19 10346 10350 9294213
   PubMed Web of Science ®Google Scholar
• Funakoshi S Murakami T Yumoto R Kiribayashi Y Takano M Role of organic anion transporting polypeptide 2 in pharmacokinetics of digoxin and β-methyldigoxin in rats J Pharm Sci 2005 94 6 1196 1203 15858844
   PubMed Web of Science ®Google Scholar
• Ren XL Xie YS Pan GX Gao XM Wang Z Zuo QA Research of periplocin on the intestinal bacterium metabolism in vitro Tianjin J Tradit Chin Med 2007 6 515 518
   Google Scholar
• Mir O Dessard-Diana B Louet AL Severe toxicity related to a pharmacokinetic interaction between docetaxel and ritonavir in HIV-infected patients Br J Clin Pharmacol 2010 69 1 99 101 20078618
   PubMed Web of Science ®Google Scholar
• Daniel WA Wójcikowski J Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressants Eur Neuropsychopharmacol 1999 9 6 483 491 10625116
   PubMed Web of Science ®Google Scholar
• Varma MV Panchagnula R Prediction of in vivo intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability J Pharm Sci 2005 94 8 1694 1704 15986467
   PubMed Web of Science ®Google Scholar
• US Food and Drug Administration Guidance for industry: Drug interaction studies – study design, data analysis, implications for dosing, and labeling recommendations 2012 Available from: http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm292362.pdf Accessed April 4, 2014
   Google Scholar
• Meier J Pharmacokinetic comparison of pindolol with other beta-adrenoceptor-blocking agents Am Heart J 1982 104 2 Pt 2 364 373 6125095
   PubMed Web of Science ®Google Scholar
• Tuncok Y Hazan E Oto O Guven H Catalyurek H Kalkan S Relationship between high serum digoxin levels and toxicity Int J Clin Pharmacol Ther 1997 35 9 366 368 9314088
   PubMed Web of Science ®Google Scholar
• Mao XQ Jia XF Zhang Y Monitoring the blood concentration of digoxin and its efficacy and toxicity 2013 40 20 3813 3814 Chinese
   Google Scholar
• Pei G Yishi L Donghua C Study on relationship between serum digoxin concentration and digoxin toxicity Chin J Hosp Pharm 2000 20 3 137 138
   Google Scholar
• Dias C Testa B Soveral G Dias M Constantino L Screening of the inhibitory effect of xenobiotics on alcohol metabolism using S9 rat liver fractions Toxicol In Vitro 2012 26 7 1177 1180 22766508
   PubMed Web of Science ®Google Scholar
• Tang L Zhou J Yang CH Xia BJ Hu M Liu ZQ Systematic studies of sulfation and glucuronidation of 12 flavonoids in the mouse liver S9 fraction reveal both unique and shared positional preferences J Agric Food Chem 2012 60 12 3223 3233 22352802
   PubMed Web of Science ®Google Scholar