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Original Research

Topical pimecrolimus inhibits high-dose UVB irradiation-induced epidermal Langerhans cell migration, via regulation of TNF-α and E-cadherin

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Pages 1817-1825 | Published online: 10 Oct 2014

References

  • Goldstein AT Thaçi D Luger T Topical calcineurin inhibitors for the treatment of vulvar dermatoses Eur J Obstet Gynecol Reprod Biol 2009 146 1 22 29 19631446
  • Martires KJ Domingo DS Hsia A Fu P Cooper KD Baron ED Effects of pimecrolimus versus triamcinolone on Langerhans cells after UV exposure Exp Dermatol 2011 20 3 280 282 21166722
  • Yin Z Xu J Zhang Z Luo D Effects of topical pimecrolimus 1% on high-dose ultraviolet B-irradiated epidermal Langerhans cells Int Immunopharmacol 2012 14 4 635 640 23079131
  • Kölgen W Both H van Weelden H Epidermal Langerhans cell depletion after artificial ultraviolet B irradiation of human skin in vivo: apoptosis versus migration J Invest Dermatol 2002 118 5 812 817 11982758
  • Antonopoulos C Cumberbatch M Mee JB IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis J Leukoc Biol 2008 83 2 361 367 17984289
  • Cumberbatch M Dearman RJ Kimber I Adhesion molecule expression by epidermal Langerhans cells and lymph node dendritic cells: a comparison Arch Dermatol Res 1996 288 12 739 744 8950453
  • Ostberg JR Kabingu E Repasky EA Thermal regulation of dendritic cell activation and migration from skin explants Int J Hyperthermia 2003 19 5 520 533 12944167
  • Bradford MM A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 1976 72 248 254 942051
  • Rowden G Expression of Ia antigens on Langerhans cells in mice, guinea pigs, and man J Invest Dermatol 1980 75 1 22 31 6446583
  • Jakob T Udey MC Regulation of E-cadherin-mediated adhesion in Langerhans cell-like dendritic cells by inflammatory mediators that mobilize Langerhans cells in vivo J Immunol 1998 160 8 4067 4073 9558117
  • Lan CC Yu HS Wu CS Kuo HY Chai CY Chen GS FK506 inhibits tumour necrosis factor-alpha secretion in human keratinocytes via regulation of nuclear factor-kappaB Br J Dermatol 2005 153 4 725 732 16181452
  • Meingassner JG Kowalsky E Schwendinger H Elbe-Bürger A Stütz A Pimecrolimus does not affect Langerhans cells in murine epidermis Br J Dermatol 2003 149 4 853 857 14616380
  • Yamagami S Hamrah P Miyamoto K CCR5 chemokine receptor mediates recruitment of MHC class II-positive Langerhans cells in the mouse corneal epithelium Invest Ophthalmol Vis Sci 2005 46 4 1201 1207 15790880
  • Sato N Ahuja SK Quinones M CC chemokine receptor (CCR)2 is required for Langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokines, b cell outgrowth, and sustained neutrophilic inflammation J Exp Med 2000 192 2 205 218 10899907
  • Matsuzawa T Kawamura T Ogawa Y Oral administration of the CCR5 inhibitor, maraviroc, blocks HIV ex vivo infection of Langerhans cells within the epithelium J Invest Dermatol 2013 133 12 2803 2805 23648547
  • Fleming MD Pinkus JL Fournier MV Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosis Blood 2003 101 7 2473 2475 12642342
  • Stutte S Quast T Gerbitzki N Requirement of CCL17 for CCR7-and CXCR4-dependent migration of cutaneous dendritic cells Proc Natl Acad Sci U S A 2010 107 19 8736 8741 20421491
  • Villablanca EJ Mora JR A two-step model for Langerhans cell migration to skin-draining LN Eur J Immunol 2008 38 11 2975 2980 18991275
  • Ohl L Mohaupt M Czeloth N CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions Immunity 2004 21 2 279 288 15308107
  • Price AA Cumberbatch M Kimber I Ager A Alpha 6 integrins are required for Langerhans cell migration from the epidermis J Exp Med 1997 186 10 1725 1735 9362532
  • Koch S Kohl K Klein E von Bubnoff D Bieber T Skin homing of Langerhans cell precursors: adhesion, chemotaxis, and migration J Allergy Clin Immunol 2006 117 1 163 168 16387601
  • Randolph GJ Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators Semin Immunol 2001 13 5 267 274 11502161