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Review

Profile of paritaprevir/ritonavir/ombitasvir plus dasabuvir in the treatment of chronic hepatitis C virus genotype 1 infection

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Pages 6083-6094 | Published online: 13 Nov 2015

References

  • World Health OrganizationGuidelines for the Screening, Care and Treatment of Persons with Hepatitis C InfectionGenevaWorld Health Organization2014
  • SmithBDMorganRLBeckettGACenters for Disease Control and PreventionRecommendations for the identification of chronic hepatitis C virus infection among persons born during 1945–1965MMWR Recomm Rep201261RR–413222895429
  • Hepatitis C Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C [webpage on the Internet]. American Association for the Study of Liver Diseases (AASLD), Infectious Diseases Society of America (IDSA) Available from: http://www.hcvguidelines.org/Accessed September 10, 2015
  • Viekira Pak (ombitasvir, paritaprevir, and ritonavir tablets; dasabuvir tablets) copackaged for oral use [prescribing information]North ChicagoAbbVie Inc2015
  • Pilot-MatiasTTripathiRCohenDIn vitro and in vivo antiviral activity and resistance profile of the hepatitis C virus NS3/4A protease inhibitor ABT-450Antimicrob Agents Chemother201559298899725451053
  • GentileIBorgiaFBuonomoARZappuloECastaldoGBorgiaGABT-450: a novel protease inhibitor for the treatment of hepatitis C virus infectionCurr Med Chem201421283261327025005190
  • BadriPDuttaSCoakleyEPharmacokinetics and dose recommendations for cyclosporine and tacrolimus when coadministered with ABT-450, ombitasvir, and dasabuvirAm J Transplant20151551313132225708713
  • FridellRAQiuDValeraLWangCRoseREGaoMDistinct functions of NS5A in hepatitis C virus RNA replication uncovered by studies with the NS5A inhibitor BMS-790052J Virol201185147312732021593143
  • DeGoeyDARandolphJTLiuDDiscovery of ABT-267, a pan-genotypic inhibitor of HCV NS5AJ Med Chem20145752047205724400777
  • LeeCDaclatasvir: potential role in hepatitis CDrug Des Devel Ther2013712231233
  • GentileIBuonomoARBorgiaGOmbitasvir: a potent pan-genotypic inhibitor of NS5A for the treatment of hepatitis C virus infectionExpert Rev Anti Infect Ther20141291033104325074011
  • KrishnanPBeyerJMistryNIn vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis C virus NS5AAntimicrob Agents Chemother201559297998725451055
  • KatiWKoevGIrvinMIn vitro activity and resistance profile of dasabuvir, a nonnucleoside hepatitis C virus polymerase inhibitorAntimicrob Agents Chemother20155931505151125534735
  • GentileIBuonomoARBorgiaGDasabuvir: a non-nucleoside inhibitor of NS5B for the treatment of hepatitis C virus infectionRev Recent Clin Trials20149211512324882169
  • KhatriAMenonRMarburyTCPharmacokinetics and safety of coadministered paritaprevir plus ritonavir (paritaprevir/r), ombitasvir, and dasabuvir in hepatic impairmentJ Hepatol Epub2015610
  • FeldJJKowdleyKVCoakleyETreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirinN Engl J Med2014370171594160324720703
  • ZeuzemSJacobsonIMBaykalTRetreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirinN Engl J Med2014370171604161424720679
  • FerenciPBernsteinDLalezariJPEARL-III Study; PEARL-IV StudyABT-450/r-ombitasvir and dasabuvir with or without ribavirin for HCVN Engl J Med2014370211983199224795200
  • AndreonePColomboMGEnejosaJVABT-450, ritonavir, ombitasvir, and dasabuvir achieves 97% and 100% sustained virologic response with or without ribavirin in treatment-experienced patients with HCV genotype 1b infectionGastroenterology20141472359365.e124818763
  • KumadaHChayamaKRodriguesLJrRandomized phase 3 trial of ombitasvir/paritaprevir/ritonavir for hepatitis C virus genotype 1b-infected Japanese patients with or without cirrhosisHepatology Epub201573
  • PoordadFHezodeCTrinhRABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosisN Engl J Med2014370211973198224725237
  • FeldJJMorenoCTrinhRTurquoise-III: safety and efficacy of 12-week ribavirin-free treatment for patients with HCV genotype 1b and cirrhosis[Abstract P226.] 15th Annual International Symposium on Viral Hepatitis and Liver DiseaseJune 26–28 2015Berlin, Germany
  • ChayamaKNotsumataKKurosakiMRandomized trial of interferon- and ribavirin-free ombitasvir/paritaprevir/ritonavir in treatment-experienced hepatitis C virus-infected patientsHepatology20156151523153225644279
  • SulkowskiMSEronJJWylesDOmbitasvir, paritaprevir co-dosed with ritonavir, dasabuvir, and ribavirin for hepatitis C in patients co-infected with HIV-1: a randomized trialJAMA2015313121223123125706092
  • KwoPYMantryPSCoakleyEAn interferon-free antiviral regimen for HCV after liver transplantationN Engl J Med2014371252375238225386767
  • Toussaint-MillerKAAndresJTreatment considerations for unique patient populations with HCV genotype 1 infectionAnn Pharmacother20154991015103026139639
  • GrahamCSBadenLRYuEInfluence of human immunodeficiency virus infection on the course of hepatitis C virus infection: a meta-analysisClin Infect Dis200133456256911462196
  • PockrosPJReddyKRMantryPSL01 : safety of ombitasvir/paritaprevir/ritonavir plus dasabuvir for treating HCV GT1 infection in patients with severe renal impairment or end-stage renal disease: the Ruby-I studyJ Hepatol201562S257S261
  • MenonRMBadriPSWangTDrug-drug interaction profile of the all-oral anti-hepatitis C virus regimen of paritaprevir/ritonavir, ombitasvir, and dasabuvirJ Hepatol2015631202925646891
  • LalezariJSullivanJGVarunokPOmbitasvir/paritaprevir/r and dasabuvir plus ribavirin in HCV genotype 1-infected patients on methadone or buprenorphineJ Hepatol201563236436925839406
  • BurgessSPartoviNYoshidaEMErbSRAzalgaraVMHussainiTDrug interactions with direct-acting antivirals for hepatitis C: implications for HIV and transplant patientsAnn Pharmacother201549667468725770114
  • SorianoVLabargaPBarreiroPDrug interactions with new hepatitis C oral drugsExpert Opin Drug Metab Toxicol201511333334125553890
  • SimmondsPGenetic diversity and evolution of hepatitis C virus – 15 years onJ Gen Virol200485Pt 113173318815483230
  • RongLDahariHRibeiroRMPerelsonASRapid emergence of protease inhibitor resistance in hepatitis C virusSci Transl Med201023030ra32
  • HalfonPLocarniniSHepatitis C virus resistance to protease inhibitorsJ Hepatol201155119220621284949
  • KuntzenTTimmJBericalANaturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patientsHepatology20084861769177819026009
  • WylesDLGutierrezJAImportance of HCV genotype 1 subtypes for drug resistance and response to therapyJ Viral Hepat201421422924024597691
  • LontokEHarringtonPHoweAHepatitis C virus drug resistance-associated substitutions: state of the art summaryHepatology Epub2015610