Lyme disease: the promise of Big Data, companion diagnostics and precision medicine

References

• StrickerRBJohnsonLLyme disease: the next decadeInfect Drug Resist201141921694904
   PubMedGoogle Scholar
• StrickerRBJohnsonLLyme disease diagnosis and treatment: lessons from the AIDS epidemicMinerva Med2010101641942521196901
   PubMed Web of Science ®Google Scholar
• de la Torre DíezICosgayaHMGarcia-ZapirainBLópez-CoronadoMBig Data in health: a literature review from the year 2005J Med Syst20164020927520614
   PubMed Web of Science ®Google Scholar
• FederHMJrJohnsonBJO’ConnellSA critical appraisal of ‘chronic Lyme disease’N Engl J Med2007357141422143017914043
   PubMed Web of Science ®Google Scholar
• StrickerRBJohnsonLLyme disease: call for a “Manhattan Project” to combat the epidemicPLoS Pathog2014101e100379624391491
   PubMed Web of Science ®Google Scholar
• StrickerRBJohnsonLThe pain of chronic Lyme disease: moving the discourse backward?FASEB J201125124085408722131364
   PubMed Web of Science ®Google Scholar
• KullbergBJBerendeAvan der MeerJWThe challenge of lyme disease: tired of the Lyme warsNeth J Med20116939810021444933
   PubMed Web of Science ®Google Scholar
• CameronDJJohnsonLBMaloneyELEvidence assessments and guideline recommendations in Lyme disease: the clinical management of known tick bites, erythema migrans rashes and persistent diseaseExpert Rev Anti Infect Ther20141291103113525077519
   PubMed Web of Science ®Google Scholar
• DelongAKBlossomBMaloneyELPhillipsSEAntibiotic retreatment of Lyme disease in patients with persistent symptoms: a biostatistical review of randomized, placebo-controlled, clinical trialsContemp Clin Trials20123361132114222922244
   PubMed Web of Science ®Google Scholar
• JohnsonLAylwardAStrickerRBHealth care access and burden of care for patients with Lyme disease: a large United States surveyHealth Policy20111021647121676482
   PubMed Web of Science ®Google Scholar
• JohnsonLWilcoxSMankoffJStrickerRBSeverity of chronic Lyme disease compared to other chronic conditions: a quality of life surveyPeer J20142e32224749006
   PubMed Web of Science ®Google Scholar
• CDCCDC provides estimate of Americans diagnosed with Lyme disease each year [press release]Atlanta, GACenters for Disease Control and Prevention2013819 Available from: http://www.cdc.gov/media/releases/2013/p0819-lyme-disease.htmlAccessed July 9, 2016
   Google Scholar
• NelsonCASahaSKugelerKJDeloreyMJShankarMBHinckleyAFMeadPSIncidence of clinician-diagnosed Lyme disease, United States 2005–2010Emerg Infect Dis20152191625163126291194
   PubMed Web of Science ®Google Scholar
• SalinasJLMindraGHaddadMBPrattRPriceSFLangerAJLeveling of tuberculosis incidence—United States, 2013–2015MMWR Morb Mortal Wkly Rep2016651127327827010173
   PubMed Web of Science ®Google Scholar
• AdrionERAucottJLemkeKWWeinerJPHealth care costs, utilization and patterns of care following Lyme diseasePLoS One2015102e011676725650808
   PubMed Web of Science ®Google Scholar
• WormserGPDattwylerRJShapiroEDThe clinical assessment, treatment, and prevention of Lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of AmericaClin Infect Dis20064391089113417029130
   PubMed Web of Science ®Google Scholar
• KumsaBSocolovschiCRaoultDParolaPNew Borrelia species detected in ixodid ticks in Oromia, EthiopiaTicks Tick Borne Dis20156340140725843811
   PubMed Web of Science ®Google Scholar
• HvidstenDStordalFLagerMBorrelia burgdorferi sensu lato-infected Ixodes ricinus collected from vegetation near the Arctic CircleTicks Tick Borne Dis20156676877326187417
   PubMed Web of Science ®Google Scholar
• EhounoudCBYaoKPDahmaniMMultiple pathogens including potential new species in tick vectors in Côte d’IvoirePLoS Negl Trop Dis2016101e000436726771308
   PubMed Web of Science ®Google Scholar
• MiddelveenMJBurkeJSapiECulture and identification of Borrelia spirochetes in human vaginal and seminal secretions [version 1; referees: 1 not approved]F1000Research20143309
   Google Scholar
• WrightSDNielsenSWExperimental infection of the white-footed mouse with Borrelia burgdorferiAm J Vet Res19905112198019872085225
   PubMed Web of Science ®Google Scholar
• GustafsonJMThe in utero and seminal transmission of Borrelia burgdorferi in Canidae [PhD thesis]Madison, WIUniversity of Wisconsin1993 Available from: http://search.library.wisc.edu/catalog/ocm29551629Accessed July 9, 2016
   Google Scholar
• AlekseevANDubininaHVExchange of Borrelia burgdorferi between Ixodes persulcatus (Ixodidae: Acarina) sexual partnersJ Med Entomol19963333513548667380
   PubMed Web of Science ®Google Scholar
• StrickerRBMiddelveenMJSexual transmission of Lyme disease: challenging the tickborne disease paradigmExpert Rev Anti-Infect Ther2015131303130626489537
   PubMed Web of Science ®Google Scholar
• CDC2015Lyme disease: two step laboratory testing process Available from: http://www.cdc.gov/lyme/diagnosistesting/labtest/twostep/index.htmlAccessed July 9, 2016
   Google Scholar
• ShahJSDu CruzINarcisoWLoWHarrisNSImproved sensitivity of Lyme disease Western blots prepared with a mixture of Borrelia burgdorferi strains 297 and B31Chronic Dis Int201417
   Google Scholar
• MaBChristenBLeungDVigo-PelfreyCSerodiagnosis of Lyme borreliosis by Western immunoblot: reactivity of various significant antibodies against Borrelia burgdorferiJ Clin Microbiol19923023703761537905
   PubMed Web of Science ®Google Scholar
• EngstromSMShoopEJohnsonRCImmunoblot interpretation criteria for serodiagnosis of early Lyme diseaseJ Clin Microbiol19953324194277714202
   PubMed Web of Science ®Google Scholar
• BrorsonOBrorsonSHTransformation of cystic forms of Borrelia burgdorferi to normal mobile spirochetesInfection19972542402469266264
   PubMed Web of Science ®Google Scholar
• MurgiaRCincoMInduction of cystic forms by different stress conditions in Borrelia burgdorferiAPMIS20041121576214961976
   PubMed Web of Science ®Google Scholar
• MacDonaldABBorrelia burgdorferi tissue morphologies and imaging methodologiesEur J Clin Microbiol Infect Dis20133281077108223479042
   PubMed Web of Science ®Google Scholar
• StrickerRBJohnsonLBorrelia burgdorferi aggrecanase activity: more evidence for persistent infection in Lyme diseaseFront Cell Infect Microbiol201334023967405
   PubMed Web of Science ®Google Scholar
• MeriläinenLHerranenASchwarzbachAGilbertLMorphological and biochemical features of Borrelia burgdorferi pleomorphic formsMicrobiology2015161Pt 351652725564498
   PubMed Web of Science ®Google Scholar
• TimmarajuVATheophilusPABalasubramanianKShakihSLueckeDFSapiEBiofilm formation by Borrelia burgdorferi sensu latoFEMS Microbiol Lett201536215fnv12026208529
   PubMed Web of Science ®Google Scholar
• SharmaBBrownAVMatluckNEHuLTLewisKBorrelia burgdorferi, the causative agent of Lyme disease, forms drug-tolerant persister cellsAntimicrob Agents Chemother20155984616462426014929
   PubMed Web of Science ®Google Scholar
• FengJWangTShiWZhangSSullivanDAuwaerterPGZhangYIdentification of novel activity against Borrelia burgdorferi persisters using an FDA approved drug libraryEmerg Microbes Infect201437e4926038747
   PubMed Web of Science ®Google Scholar
• Wikipedia2015Antibiotic timeline Available from: https://en.wikipedia.org/wiki/Timeline_of_antibioticsAccessed July 9, 2016
   Google Scholar
• SloanDJLewisJMManagement of multidrug-resistant TB: novel treatments and their expansion to low resource settingsTrans R Soc Trop Med Hyg2016110316317226884496
   PubMed Web of Science ®Google Scholar
• GhoshAKOsswaldHLPratoGRecent progress in the development of HIV-1 protease inhibitors for the treatment of HIV/AIDSJ Med Chem201659115172520826799988
   PubMed Web of Science ®Google Scholar
• ZhangXDirect anti-HCV agentsActa Pharm Sin B201661263126904396
   PubMed Web of Science ®Google Scholar
• SteimerLKlostermeierDRNA helicases in infection and diseaseRNA Biol20129275177122699555
   PubMed Web of Science ®Google Scholar
• LeitãoALCostaMCEnguitaFJUnzippers, resolvers and sensors: a structural and functional biochemistry tale of RNA helicasesInt J Mol Sci20151622269229325622248
   PubMed Web of Science ®Google Scholar
• FengJShiWZhangSZhangYPersister mechanisms in Borrelia burgdorferi: implications for improved interventionEmerg Microbes Infect201548e5126421273
   PubMed Web of Science ®Google Scholar
• GherardiniFCBorrelia burgdorferi HtrA may promote dissemination and irritationMol Microbiol201390220921323998919
   PubMed Web of Science ®Google Scholar
• RussellTMTangXGoldsteinJMBagarozziDJohnsonBJThe salt-sensitive structure and zinc inhibition of Borrelia burgdorferi protease BbHtrAMol Microbiol201699358659626480895
   PubMed Web of Science ®Google Scholar
• ColemanJLKatonaLIKuhlowCToledoAOkanNATokarzRBenachJLEvidence that two ATP-dependent (Lon) proteases in Borrelia burgdorferi serve different functionsPLoS Pathog2009511e100067619956677
   PubMed Web of Science ®Google Scholar
• KumruOSBunikisISorokinaIBergstromSZuckertWRSpecificity and role of the Borrelia burgdorferi CtpA protease in outer membrane protein processingJ Bacteriol2011193205759576521856844
   PubMed Web of Science ®Google Scholar
• Salman-DilgimenAHardyP-ORadolfJDCaimanoMJChaconasGHrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochetePLoS Pathog2013912e100384124367266
   PubMed Web of Science ®Google Scholar
• ArnoldWKSavageCRAntonicelloADStevensonBApparent role for Borrelia burgdorferi LuxS during mammalian infectionInfect Immun20158341347135325605770
   PubMed Web of Science ®Google Scholar
• ChuC-YStewartPEBestorAFunction of the Borrelia burgdorferi FtsH homolog is essential for viability both in vitro and in vivo and independent of HflK/CmBio201672e004041627094329
   PubMed Web of Science ®Google Scholar
• KhouryJDThe evolving potential of companion diagnosticsScand J Clin Lab Invest Suppl2016245S22S5427433788
   PubMedGoogle Scholar