Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins

Maryna PerepelyukDepartment of Pharmaceutical Science, College of Pharmacy, Thomas Jefferson University, Philadelphia, PA, USA

Christina MaherDepartment of Pharmaceutical Science, College of Pharmacy, Thomas Jefferson University, Philadelphia, PA, USA

Ashakumary LakshmikuttyammaDepartment of Pharmaceutical Science, College of Pharmacy, Thomas Jefferson University, Philadelphia, PA, USA

Sunday A ShoyeleDepartment of Pharmaceutical Science, College of Pharmacy, Thomas Jefferson University, Philadelphia, PA, USACorrespondence[email protected]

Pages 3533-3544 | Published online: 28 Jul 2016

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Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins

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Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins

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