International Journal of Nanomedicine, Volume 11, Issue (2016)

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International Journal of Nanomedicine, Volume 11, Issue (2016)

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Review

Review Article
Dendrimers as tunable vectors of drug delivery systems and biomedical and ocular applications
Marina Kalomiraki, Kyriaki Thermos & Nikos A Chaniotakis
Pages: 1-12
Published online: 22 Dec 2015
AbstractforDendrimers as tunable vectors of drug delivery systems and biomedical and ocular applications | Full Text | References | PDF (561.7 KB)
  • 193 Views
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Original Research

Article
In vivo near-infrared imaging for the tracking of systemically delivered mesenchymal stem cells: tropism for brain tumors and biodistribution
Seong Muk Kim, Chang Hyun Jeong, Ji Sun Woo, Chung Heon Ryu, Jeong-Hwa Lee & Sin-Soo Jeun
Pages: 13-23
Published online: 18 Dec 2015
AbstractforIn vivo near-infrared imaging for the tracking of systemically delivered mesenchymal stem cells: tropism for brain tumors and biodistribution | Full Text | References | PDF (2.8 MB)
  • 112 Views
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Open Access
Article
Biodegradable Eri silk nanoparticles as a delivery vehicle for bovine lactoferrin against MDA-MB-231 and MCF-7 breast cancer cells
Kislay Roy, Yogesh S Patel, Rupinder K Kanwar, Rangam Rajkhowa, Xungai Wang & Jagat R Kanwar
Pages: 25-44
Published online: 21 Dec 2015
AbstractforBiodegradable Eri silk nanoparticles as a delivery vehicle for bovine lactoferrin against MDA-MB-231 and MCF-7 breast cancer cells | Full Text | References | PDF (8.2 MB)
  • 116 Views
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Open Access
Article
Improved molecular fingerprint analysis employing multi-branched gold nanoparticles in conjunction with surface-enhanced Raman scattering
Jencilin Johnston, Erik N Taylor, Richard J Gilbert & Thomas J Webster
Pages: 45-53
Published online: 22 Dec 2015
AbstractforImproved molecular fingerprint analysis employing multi-branched gold nanoparticles in conjunction with surface-enhanced Raman scattering | Full Text | References | PDF (2.6 MB)
  • 50 Views
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Open Access
Article
Silver nanoparticles affect glucose metabolism in hepatoma cells through production of reactive oxygen species
Mi Jin Lee, Seung Jun Lee, Su Jin Yun, Ji-Young Jang, Hangoo Kang, Kyongmin Kim, In-Hong Choi & Sun Park
Pages: 55-68
Published online: 22 Dec 2015
AbstractforSilver nanoparticles affect glucose metabolism in hepatoma cells through production of reactive oxygen species | Full Text | References | PDF (1.4 MB)
  • 95 Views
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Open Access
Article
Nanostructured ultra-thin patches for ultrasound-modulated delivery of anti-restenotic drug
Lorenzo Vannozzi, Leonardo Ricotti, Carlo Filippeschi, Stefania Sartini, Vito Coviello, Vincenzo Piazza, Pasqualantonio Pingue, Concettina La Motta, Paolo Dario & Arianna Menciassi
Pages: 69-92
Published online: 23 Dec 2015
AbstractforNanostructured ultra-thin patches for ultrasound-modulated delivery of anti-restenotic drug | Full Text | References | PDF (7 MB)
  • 97 Views
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Open Access
Article
Tumor vascular-targeted co-delivery of anti-angiogenesis and chemotherapeutic agents by mesoporous silica nanoparticle-based drug delivery system for synergetic therapy of tumor
Xiaoyu Li, Meiying Wu, Limin Pan & Jianlin Shi
Pages: 93-105
Published online: 29 Dec 2015
AbstractforTumor vascular-targeted co-delivery of anti-angiogenesis and chemotherapeutic agents by mesoporous silica nanoparticle-based drug delivery system for synergetic therapy of tumor | Full Text | References | PDF (5 MB)
  • 148 Views
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Open Access
Article
Improving cytotoxicity against cancer cells by chemo-photodynamic combined modalities using silver-graphene quantum dots nanocomposites
Khaled Habiba, Joel Encarnacion-Rosado, Kenny Garcia-Pabon, Juan C Villalobos-Santos, Vladimir I Makarov, Javier A Avalos, Brad R Weiner & Gerardo Morell
Pages: 107-119
Published online: 24 Dec 2015
AbstractforImproving cytotoxicity against cancer cells by chemo-photodynamic combined modalities using silver-graphene quantum dots nanocomposites | Full Text | References | PDF (3.6 MB)
  • 130 Views
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Review

Review Article
Recent insights into the biological activities and drug delivery systems of tanshinones
Yuee Cai, Wenji Zhang, Zirong Chen, Zhi Shi, Chengwei He & Meiwan Chen
Pages: 121-130
Published online: 05 Jan 2016
AbstractforRecent insights into the biological activities and drug delivery systems of tanshinones | Full Text | References | PDF (425.9 KB)
  • 128 Views
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Original Research

Article
Injectable, degradable, electroactive nanocomposite hydrogels containing conductive polymer nanoparticles for biomedical applications
Qinmei Wang, Qiong Wang & Wei Teng
Pages: 131-145
Published online: 05 Jan 2016
AbstractforInjectable, degradable, electroactive nanocomposite hydrogels containing conductive polymer nanoparticles for biomedical applications | Full Text | References | PDF (3.4 MB)
  • 134 Views
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Article
Size- and shape-dependent clinical and mycological efficacy of silver nanoparticles on dandruff
Mohammad F Anwar, Deepak Yadav, Swati Jain, Sumeet Kapoor, Shweta Rastogi, Indu Arora & Mohammed Samim
Pages: 147-161
Published online: 06 Jan 2016
AbstractforSize- and shape-dependent clinical and mycological efficacy of silver nanoparticles on dandruff | Full Text | References | PDF (4.1 MB)
  • 112 Views
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Article
Effect of ultrafine poly(ε-caprolactone) fibers on calcium phosphate cement: in vitro degradation and in vivo regeneration
Boyuan Yang, Yi Zuo, Qin Zou, Limei Li, Jidong Li, Yi Man & Yubao Li
Pages: 163-177
Published online: 07 Jan 2016
AbstractforEffect of ultrafine poly(ε-caprolactone) fibers on calcium phosphate cement: in vitro degradation and in vivo regeneration | Full Text | References | PDF (11.4 MB)
  • 56 Views
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Open Access
Article
A combination of sorafenib and nilotinib reduces the growth of castrate-resistant prostate cancer
Monica Archibald, Tara Pritchard, Hayley Nehoff, Rhonda J Rosengren, Khaled Greish & Sebastien Taurin
Pages: 179-201
Published online: 08 Jan 2016
AbstractforA combination of sorafenib and nilotinib reduces the growth of castrate-resistant prostate cancer | Full Text | References | PDF (3.4 MB)
  • 68 Views
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Open Access
Article
A new target ligand Ser–Glu for PEPT1-overexpressing cancer imaging
Tongcheng Dai, Na Li, Lingzhi Zhang, Yuanxing Zhang & Qin Liu
Pages: 203-212
Published online: 11 Jan 2016
AbstractforA new target ligand Ser–Glu for PEPT1-overexpressing cancer imaging | Full Text | References | PDF (2.5 MB)
  • 69 Views
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Open Access
Article
Novel electrosprayed nanospherules for enhanced aqueous solubility and oral bioavailability of poorly water-soluble fenofibrate
Abid Mehmood Yousaf, Omer Mustapha, Dong Wuk Kim, Dong Shik Kim, Kyeong Soo Kim, Sung Giu Jin, Chul Soon Yong, Yu Seok Youn, Yu-Kyoung Oh, Jong Oh Kim & Han-Gon Choi
Pages: 213-221
Published online: 12 Jan 2016
AbstractforNovel electrosprayed nanospherules for enhanced aqueous solubility and oral bioavailability of poorly water-soluble fenofibrate | Full Text | References | PDF (1.5 MB)
  • 107 Views
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Article
UV photofunctionalization promotes nano-biomimetic apatite deposition on titanium
Makiko Saita, Takayuki Ikeda, Masahiro Yamada, Katsuhiko Kimoto, Masaichi Chang-Il Lee & Takahiro Ogawa
Pages: 223-234
Published online: 12 Jan 2016
AbstractforUV photofunctionalization promotes nano-biomimetic apatite deposition on titanium | Full Text | References | PDF (5.3 MB)
  • 59 Views
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Open Access
Article
Quantitative detection of the tumor-associated antigen large external antigen in colorectal cancer tissues and cells using quantum dot probe
Shuo Wang, Wanming Li, Dezheng Yuan, Jindan Song & Jin Fang
Pages: 235-247
Published online: 13 Jan 2016
AbstractforQuantitative detection of the tumor-associated antigen large external antigen in colorectal cancer tissues and cells using quantum dot probe | Full Text | References | PDF (3.4 MB)
  • 250 Views
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Open Access
Article
In vitro apoptotic and DNA damaging potential of nanobarium oxide
Saud Alarifi, Daoud Ali & Widad Al-Bishri
Pages: 249-257
Published online: 13 Jan 2016
AbstractforIn vitro apoptotic and DNA damaging potential of nanobarium oxide | Full Text | References | PDF (2.6 MB)
  • 47 Views
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Open Access
Article
Preparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease
Masoumeh Firouzamandi, Hassan Moeini, Seyed Davood Hosseini, Mohd Hair Bejo, Abdul Rahman Omar, Parvaneh Mehrbod, Mohamed E El Zowalaty, Thomas J Webster & Aini Ideris
Pages: 259-267
Published online: 14 Jan 2016
AbstractforPreparation, characterization, and in ovo vaccination of dextran-spermine nanoparticle DNA vaccine coexpressing the fusion and hemagglutinin genes against Newcastle disease | Full Text | References | PDF (1.2 MB)
  • 69 Views
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Open Access
Article
Fullerene mediates proliferation and cardiomyogenic differentiation of adipose-derived stem cells via modulation of MAPK pathway and cardiac protein expression
Tong Hao, Jin Zhou, Shuanghong Lü, Boguang Yang, Yan Wang, Wancai Fang, Xiaoxia Jiang, Qiuxia Lin, Junjie Li & Changyong Wang
Pages: 269-283
Published online: 18 Jan 2016
AbstractforFullerene mediates proliferation and cardiomyogenic differentiation of adipose-derived stem cells via modulation of MAPK pathway and cardiac protein expression | Full Text | References | PDF (8.3 MB)
  • 66 Views
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Article
Controlled-release of tetracycline and lovastatin by poly(d,l-lactide-co-glycolide acid)-chitosan nanoparticles enhances periodontal regeneration in dogs
Bor-Shiunn Lee, Chien-Chen Lee, Yi-Ping Wang, Hsiao-Jan Chen, Chern-Hsiung Lai, Wan-Ling Hsieh & Yi-Wen Chen
Pages: 285-297
Published online: 18 Jan 2016
AbstractforControlled-release of tetracycline and lovastatin by poly(d,l-lactide-co-glycolide acid)-chitosan nanoparticles enhances periodontal regeneration in dogs | Full Text | References | PDF (2.7 MB)
  • 197 Views
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Article
Targeted modulation of cell differentiation in distinct regions of the gastrointestinal tract via oral administration of differently PEG-PEI functionalized mesoporous silica nanoparticles
Diti Desai, Neeraj Prabhakar, Veronika Mamaeva, Didem Şen Karaman, Iris AK Lähdeniemi, Cecilia Sahlgren, Jessica M Rosenholm & Diana M Toivola
Pages: 299-313
Published online: 18 Jan 2016
AbstractforTargeted modulation of cell differentiation in distinct regions of the gastrointestinal tract via oral administration of differently PEG-PEI functionalized mesoporous silica nanoparticles | Full Text | References | PDF (8.7 MB)
  • 120 Views
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Article
Synthesis of antimicrobial silver nanoparticles through a photomediated reaction in an aqueous environment
Rafał Banasiuk, Joanna E Frackowiak, Marta Krychowiak, Marta Matuszewska, Anna Kawiak, Magdalena Ziabka, Zofia Lendzion-Bielun, Magdalena Narajczyk & Aleksandra Krolicka
Pages: 315-324
Published online: 19 Jan 2016
AbstractforSynthesis of antimicrobial silver nanoparticles through a photomediated reaction in an aqueous environment | Full Text | References | PDF (6.4 MB)
  • 57 Views
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Open Access
Article
Liposomes coated with N-trimethyl chitosan to improve the absorption of harmine in vivo and in vitro
Wei-liang Chen, Zhi-Qiang Yuan, Yang Liu, Shu-di Yang, Chun-ge Zhang, Ji-zhao Li, Wen-jing Zhu, Fang Li, Xiao-feng Zhou, Yi-mei Lin & Xue-nong Zhang
Pages: 325-336
Published online: 19 Jan 2016
AbstractforLiposomes coated with N-trimethyl chitosan to improve the absorption of harmine in vivo and in vitro | Full Text | References | PDF (3.1 MB)
  • 80 Views
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Open Access
Article
Anionic clay as the drug delivery vehicle: tumor targeting function of layered double hydroxide-methotrexate nanohybrid in C33A orthotopic cervical cancer model
Goeun Choi, Huiyan Piao, Zeid A Alothman, Ajayan Vinu, Chae-Ok Yun & Jin-Ho Choy
Pages: 337-348
Published online: 20 Jan 2016
AbstractforAnionic clay as the drug delivery vehicle: tumor targeting function of layered double hydroxide-methotrexate nanohybrid in C33A orthotopic cervical cancer model | Full Text | References | PDF (4.3 MB)
  • 129 Views
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Review

Review Article
Impact of single-walled carbon nanotubes on the embryo: a brief review
Ala-Eddin Al Moustafa, Etienne Mfoumou, Dacian E Roman, Vahe Nerguizian, Anas Alazzam, Ion Stiharu & Amber Yasmeen
Pages: 349-355
Published online: 21 Jan 2016
AbstractforImpact of single-walled carbon nanotubes on the embryo: a brief review | Full Text | References | PDF (759.3 KB)
  • 52 Views
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Original Research

Article
Quantitative [Fe]MRI of PSMA-targeted SPIONs specifically discriminates among prostate tumor cell types based on their PSMA expression levels
Laurel O Sillerud
Pages: 357-372
Published online: 20 Jan 2016
AbstractforQuantitative [Fe]MRI of PSMA-targeted SPIONs specifically discriminates among prostate tumor cell types based on their PSMA expression levels | Full Text | References | PDF (2.6 MB)
  • 50 Views
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Open Access
Article
Silver nanoparticles/chitosan oligosaccharide/poly(vinyl alcohol) nanofiber promotes wound healing by activating TGFβ1/Smad signaling pathway
Chen-wen Li, Qing Wang, Jing Li, Min Hu, San-jun Shi, Zi-wei Li, Guo-lin Wu, Huan-huan Cui, Yuan-yuan Li, Qian Zhang, Xiu-heng Yu & Lai-chun Lu
Pages: 373-387
Published online: 21 Jan 2016
AbstractforSilver nanoparticles/chitosan oligosaccharide/poly(vinyl alcohol) nanofiber promotes wound healing by activating TGFβ1/Smad signaling pathway | Full Text | References | PDF (6.8 MB)
  • 145 Views
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Open Access
Article
Preclinical animal study and human clinical trial data of co-electrospun poly(l-lactide-co-caprolactone) and fibrinogen mesh for anterior pelvic floor reconstruction
Xujun Wu, Yuru Wang, Cancan Zhu, Xiaowen Tong, Ming Yang, Li Yang, Zhang Liu, Weihong Huang, Feng Wu, Honghai Zong, Huaifang Li & Hongbing He
Pages: 389-397
Published online: 04 Feb 2016
AbstractforPreclinical animal study and human clinical trial data of co-electrospun poly(l-lactide-co-caprolactone) and fibrinogen mesh for anterior pelvic floor reconstruction | Full Text | References | PDF (1.9 MB)
  • 73 Views
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Article
A novel type of self-assembled nanoparticles as targeted gene carriers: an application for plasmid DNA and antimicroRNA oligonucleotide delivery
Yanliang Zhu, Gaofeng Liang, Bo Sun, Tian Tian, Feihu Hu & Zhongdang Xiao
Pages: 399-411
Published online: 27 Jan 2016
AbstractforA novel type of self-assembled nanoparticles as targeted gene carriers: an application for plasmid DNA and antimicroRNA oligonucleotide delivery | Full Text | References | PDF (4.2 MB)
  • 51 Views
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Article
Folic acid targeted Mn:ZnS quantum dots for theranostic applications of cancer cell imaging and therapy
Ibrahim Birma Bwatanglang, Faruq Mohammad, Nor Azah Yusof, Jaafar Abdullah, Mohd Zobir Hussein, Noorjahan Banu Alitheen & Nadiah Abu
Pages: 413-428
Published online: 22 Jan 2016
AbstractforFolic acid targeted Mn:ZnS quantum dots for theranostic applications of cancer cell imaging and therapy | Full Text | References | PDF (2.7 MB)
  • 161 Views
  • 19 CrossRef citations
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Article
Enhanced osteogenic activity and anti-inflammatory properties of Lenti-BMP-2-loaded TiO2 nanotube layers fabricated by lyophilization following trehalose addition
Xiaochen Zhang, Zhiyuan Zhang, Gang Shen & Jun Zhao
Pages: 429-439
Published online: 28 Feb 2023
AbstractforEnhanced osteogenic activity and anti-inflammatory properties of Lenti-BMP-2-loaded TiO2 nanotube layers fabricated by lyophilization following trehalose addition | Full Text | References | PDF (3.8 MB)
  • 71 Views
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Article
Miconazole-loaded solid lipid nanoparticles: formulation and evaluation of a novel formula with high bioavailability and antifungal activity
Bader Mubarak Aljaeid & Khaled Mohamed Hosny
Pages: 441-447
Published online: 25 Jan 2016
AbstractforMiconazole-loaded solid lipid nanoparticles: formulation and evaluation of a novel formula with high bioavailability and antifungal activity | Full Text | References | PDF (705.6 KB)
  • 570 Views
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Article
Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy
Qiuchen Chu, Hong Xu, Meng Gao, Xin Guan, Hongyan Liu, Sa Deng, Xiaokui Huo, Kexin Liu, Yan Tian & Xiaochi Ma
Pages: 449-463
Published online: 28 Feb 2023
AbstractforLiver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy | Full Text | References | PDF (5 MB)
  • 52 Views
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Article
Local delivery of controlled-release simvastatin to improve the biocompatibility of polyethylene terephthalate artificial ligaments for reconstruction of the anterior cruciate ligament
Peng Zhang, Fei Han, Yunxia Li, Jiwu Chen, Tianwu Chen, Yunlong Zhi, Jia Jiang, Chao Lin, Shiyi Chen & Peng Zhao
Pages: 465-478
Published online: 27 Jan 2016
AbstractforLocal delivery of controlled-release simvastatin to improve the biocompatibility of polyethylene terephthalate artificial ligaments for reconstruction of the anterior cruciate ligament | Full Text | References | PDF (5.4 MB)
  • 215 Views
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Article
Enhanced chondrocyte culture and growth on biologically inspired nanofibrous cell culture dishes
Garima Bhardwaj & Thomas J Webster
Pages: 479-483
Published online: 28 Feb 2023
AbstractforEnhanced chondrocyte culture and growth on biologically inspired nanofibrous cell culture dishes | Full Text | References | PDF (1.8 MB)
  • 46 Views
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Article
Heterogeneous response of different tumor cell lines to methotrexate-coupled nanoparticles in presence of hyperthermia
Marcus Stapf, Nadine Pömpner, Ulf Teichgräber & Ingrid Hilger
Pages: 485-500
Published online: 04 Feb 2016
AbstractforHeterogeneous response of different tumor cell lines to methotrexate-coupled nanoparticles in presence of hyperthermia | Full Text | References | PDF (1.5 MB)
  • 51 Views
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Article
Efficient inhibition of ovarian cancer by degradable nanoparticle-delivered survivin T34A gene
Li Luo, Ting Du, Jiumeng Zhang, Wei Zhao, Hao Cheng, Yuping Yang, Yujiao Wu, Chunmei Wang, Ke Men & Maling Gou
Pages: 501-513
Published online: 02 Feb 2016
AbstractforEfficient inhibition of ovarian cancer by degradable nanoparticle-delivered survivin T34A gene | Full Text | References | PDF (4.1 MB)
  • 53 Views
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Article
Preparation of finasteride capsules-loaded drug nanoparticles: formulation, optimization, in vitro, and pharmacokinetic evaluation
Tarek A Ahmed
Pages: 515-527
Published online: 28 Feb 2023
AbstractforPreparation of finasteride capsules-loaded drug nanoparticles: formulation, optimization, in vitro, and pharmacokinetic evaluation | Full Text | References | PDF (2.2 MB)
  • 231 Views
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Article
Cytotoxicity of CdTe quantum dots in human umbilical vein endothelial cells: the involvement of cellular uptake and induction of pro-apoptotic endoplasmic reticulum stress
Ming Yan, Yun Zhang, Haiyan Qin, Kezhou Liu, Miao Guo, Yakun Ge, Mingen Xu, Yonghong Sun & Xiaoxiang Zheng
Pages: 529-542
Published online: 02 Feb 2016
AbstractforCytotoxicity of CdTe quantum dots in human umbilical vein endothelial cells: the involvement of cellular uptake and induction of pro-apoptotic endoplasmic reticulum stress | Full Text | References | PDF (4.6 MB)
  • 66 Views
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Article
Mechanistic analysis of Zein nanoparticles/PLGA triblock in situ forming implants for glimepiride
Osama Abdelhakim Aly Ahmed, Ahmed Samir Zidan & Maan Khayat
Pages: 543-555
Published online: 03 Feb 2016
AbstractforMechanistic analysis of Zein nanoparticles/PLGA triblock in situ forming implants for glimepiride | Full Text | References | PDF (1.8 MB)
  • 121 Views
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Article
Nanodiamonds coupled with 5,7-dimethoxycoumarin, a plant bioactive metabolite, interfere with the mitotic process in B16F10 cells altering the actin organization
Angelo Gismondi, Valentina Nanni, Giacomo Reina, Silvia Orlanducci, Maria Letizia Terranova & Antonella Canini
Pages: 557-574
Published online: 03 Feb 2016
AbstractforNanodiamonds coupled with 5,7-dimethoxycoumarin, a plant bioactive metabolite, interfere with the mitotic process in B16F10 cells altering the actin organization | Full Text | References | PDF (5.7 MB)
  • 92 Views
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Article
A blue fluorescent labeling technique utilizing micro- and nanoparticles for tracking in LIVE/DEAD® stained pathogenic biofilms of Staphylococcus aureus and Burkholderia cepacia
Mareike Klinger-Strobel, Julia Ernst, Christian Lautenschläger, Mathias W Pletz, Dagmar Fischer & Oliwia Makarewicz
Pages: 575-583
Published online: 05 Feb 2016
AbstractforA blue fluorescent labeling technique utilizing micro- and nanoparticles for tracking in LIVE/DEAD® stained pathogenic biofilms of Staphylococcus aureus and Burkholderia cepacia | Full Text | References | PDF (3.9 MB)
  • 111 Views
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Article
Peen treatment on a titanium implant: effect of roughness, osteoblast cell functions, and bonding with bone cement
Morshed Khandaker, Shahram Riahinezhad, Fariha Sultana, Melville B Vaughan, Joshua Knight & Tracy L Morris
Pages: 585-595
Published online: 04 Feb 2016
AbstractforPeen treatment on a titanium implant: effect of roughness, osteoblast cell functions, and bonding with bone cement | Full Text | References | PDF (2.8 MB)
  • 66 Views
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Article
Cytoprotective effect of glutaraldehyde erythropoietin on HEK293 kidney cells after silver nanoparticle exposure
Kanidta Sooklert, Supreecha Chattong, Krissanapong Manotham, Chawikan Boonwong, I-yanut Klaharn, Depicha Jindatip & Amornpun Sereemaspun
Pages: 597-605
Published online: 12 Feb 2016
AbstractforCytoprotective effect of glutaraldehyde erythropoietin on HEK293 kidney cells after silver nanoparticle exposure | Full Text | References | PDF (2.1 MB)
  • 103 Views
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Article
A novel redox-sensitive system based on single-walled carbon nanotubes for chemo-photothermal therapy and magnetic resonance imaging
Lin Hou, Xiaomin Yang, Junxiao Ren, Yongchao Wang, Huijuan Zhang, Qianhua Feng, Yuyang Shi, Xiaoning Shan, Yujie Yuan & Zhenzhong Zhang
Pages: 607-624
Published online: 05 Feb 2016
AbstractforA novel redox-sensitive system based on single-walled carbon nanotubes for chemo-photothermal therapy and magnetic resonance imaging | Full Text | References | PDF (6.5 MB)
  • 94 Views
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Article
Toward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles
Ulrika Carlander, Dingsheng Li, Olivier Jolliet, Claude Emond & Gunnar Johanson
Pages: 625-640
Published online: 11 Feb 2016
AbstractforToward a general physiologically-based pharmacokinetic model for intravenously injected nanoparticles | Full Text | References | PDF (2 MB)
  • 118 Views
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Article
Gold nanoparticles enhance the effect of tyrosine kinase inhibitors in acute myeloid leukemia therapy
Bobe Petrushev, Sanda Boca, Timea Simon, Cristian Berce, Ioana Frinc, Delia Dima, Sonia Selicean, Grigore-Aristide Gafencu, Alina Tanase, Mihnea Zdrenghea, Adrian Florea, Sorina Suarasan, Liana Dima, Raluca Stanciu, Ancuta Jurj, Anca Buzoianu, Andrei Cucuianu, Simion Astilean, Alexandru Irimie, Ciprian Tomuleasa & Ioana Berindan-Neagoe
Pages: 641-660
Published online: 15 Feb 2016
AbstractforGold nanoparticles enhance the effect of tyrosine kinase inhibitors in acute myeloid leukemia therapy | Full Text | References | PDF (12.1 MB)
  • 118 Views
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Article
Development of nanoantibiotic delivery system using cockle shell-derived aragonite nanoparticles for treatment of osteomyelitis
Lamin Saidykhan, Md Zuki Bin Abu Bakar, Yaya Rukayadi, Aminu Umar Kura & Saiful Yazan Latifah
Pages: 661-673
Published online: 15 Feb 2016
AbstractforDevelopment of nanoantibiotic delivery system using cockle shell-derived aragonite nanoparticles for treatment of osteomyelitis | Full Text | References | PDF (2.3 MB)
  • 118 Views
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Article
Using basic fibroblast growth factor nanoliposome combined with ultrasound-introduced technology to early intervene the diabetic cardiomyopathy
Ying-Zheng Zhao, Ming Zhang, Xin-Qiao Tian, Lei Zheng & Cui-Tao Lu
Pages: 675-686
Published online: 18 Feb 2016
AbstractforUsing basic fibroblast growth factor nanoliposome combined with ultrasound-introduced technology to early intervene the diabetic cardiomyopathy | Full Text | References | PDF (4.3 MB)
  • 42 Views
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Article
Lysine-functionalized nanodiamonds as gene carriers: development of stable colloidal dispersion for in vitro cellular uptake studies and siRNA delivery application
Saniya Alwani, Randeep Kaur, Deborah Michel, Jackson M Chitanda, Ronald E Verrall, Chithra Karunakaran & Ildiko Badea
Pages: 687-702
Published online: 19 Feb 2016
AbstractforLysine-functionalized nanodiamonds as gene carriers: development of stable colloidal dispersion for in vitro cellular uptake studies and siRNA delivery application | Full Text | References | PDF (4.5 MB)
  • 74 Views
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Article
Development of a robust pH-sensitive polyelectrolyte ionomer complex for anticancer nanocarriers
Chaemin Lim, Yu Seok Youn, Kyung Soo Lee, Ngoc Ha Hoang, Taehoon Sim, Eun Seong Lee & Kyung Taek Oh
Pages: 703-713
Published online: 22 Feb 2016
AbstractforDevelopment of a robust pH-sensitive polyelectrolyte ionomer complex for anticancer nanocarriers | Full Text | References | PDF (1.7 MB)
  • 66 Views
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Article
Thidiazuron-enhanced biosynthesis and antimicrobial efficacy of silver nanoparticles via improving phytochemical reducing potential in callus culture of Linum usitatissimum L.
Sumaira Anjum & Bilal Haider Abbasi
Pages: 715-728
Published online: 22 Feb 2016
AbstractforThidiazuron-enhanced biosynthesis and antimicrobial efficacy of silver nanoparticles via improving phytochemical reducing potential in callus culture of Linum usitatissimum L. | Full Text | References | PDF (3.4 MB)
  • 155 Views
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Article
Degradation of the electrospun silica nanofiber in a biological medium for primary hippocampal neuron – effect of surface modification
Z Vivian Feng, Wen Shuo Chen, Khomson Keratithamkul, Michael Stoick, Brittany Kapala, Eryn Johnson, An-Chi Huang, Ting Yu Chin, Yui Whei Chen-Yang & Mong-Lin Yang
Pages: 729-741
Published online: 26 Feb 2016
AbstractforDegradation of the electrospun silica nanofiber in a biological medium for primary hippocampal neuron – effect of surface modification | Full Text | References | PDF (4.4 MB)
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Article
Pigment epithelial-derived factor gene loaded novel COOH-PEG-PLGA-COOH nanoparticles promoted tumor suppression by systemic administration
Ting Yu, Bei Xu, Lili He, Shan Xia, Yan Chen, Jun Zeng, Yongmei Liu, Shuangzhi Li, Xiaoyue Tan, Ke Ren, Shaohua Yao & Xiangrong Song
Pages: 743-759
Published online: 25 Feb 2016
AbstractforPigment epithelial-derived factor gene loaded novel COOH-PEG-PLGA-COOH nanoparticles promoted tumor suppression by systemic administration | Full Text | References | PDF (4.9 MB)
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Article
Self-assembled lecithin/chitosan nanoparticles for oral insulin delivery: preparation and functional evaluation
Liyao Liu, Cuiping Zhou, Xuejun Xia & Yuling Liu
Pages: 761-769
Published online: 24 Feb 2016
AbstractforSelf-assembled lecithin/chitosan nanoparticles for oral insulin delivery: preparation and functional evaluation | Full Text | References | PDF (1.7 MB)
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Article
The potential applications of fibrin-coated electrospun polylactide nanofibers in skin tissue engineering
Marketa Bacakova, Jana Musilkova, Tomas Riedel, Denisa Stranska, Eduard Brynda, Margit Zaloudkova & Lucie Bacakova
Pages: 771-789
Published online: 25 Feb 2016
AbstractforThe potential applications of fibrin-coated electrospun polylactide nanofibers in skin tissue engineering | Full Text | References | PDF (18 MB)
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Article
Targeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: from synthesis to proof-of-concept in vitro studies
Jolanda Spadavecchia, Dania Movia, Caroline Moore, Ciaran Manus Maguire, Hanane Moustaoui, Sandra Casale, Yuri Volkov & Adriele Prina-Mello
Pages: 791-822
Published online: 26 Feb 2016
AbstractforTargeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: from synthesis to proof-of-concept in vitro studies | Full Text | References | PDF (8.8 MB)
  • 220 Views
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Article
Three-dimensional culture and interaction of cancer cells and dendritic cells in an electrospun nano-submicron hybrid fibrous scaffold
Tae-Eon Kim, Chang Gun Kim, Jin Soo Kim, Songwan Jin, Sik Yoon, Hae-Rahn Bae, Jeong-Hwa Kim, Young Hun Jeong & Jong-Young Kwak
Pages: 823-835
Published online: 02 Mar 2016
AbstractforThree-dimensional culture and interaction of cancer cells and dendritic cells in an electrospun nano-submicron hybrid fibrous scaffold | Full Text | References | PDF (5.4 MB)
  • 119 Views
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Article
Design of a novel theranostic nanomedicine: synthesis and physicochemical properties of a biocompatible polyphosphazene–platinum(II) conjugate
Prakash G Avaji, Jung Hyun Park, Hyun Jeong Lee, Yong Joo Jun, Kyung Su Park, Kyung Eun Lee, Soo-Jin Choi, Hwa Jeong Lee & Youn Soo Sohn
Pages: 837-851
Published online: 02 Mar 2016
AbstractforDesign of a novel theranostic nanomedicine: synthesis and physicochemical properties of a biocompatible polyphosphazene–platinum(II) conjugate | Full Text | References | PDF (3.3 MB)
  • 52 Views
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Article
Liquid crystal nanoparticle formulation as an oral drug delivery system for liver-specific distribution
Dong Ryeol Lee, Ji Su Park, Il Hak Bae, Yan Lee & B Moon Kim
Pages: 853-871
Published online: 03 Mar 2016
AbstractforLiquid crystal nanoparticle formulation as an oral drug delivery system for liver-specific distribution | Full Text | References | PDF (5.2 MB)
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Article
Apoptosis inducing ability of silver decorated highly reduced graphene oxide nanocomposites in A549 lung cancer
Merajuddin Khan, Mujeeb Khan, Abdulhadi H Al-Marri, Abdulrahman Al-Warthan, Hamad Z Alkhathlan, Mohammed Rafiq H Siddiqui, Vadithe Lakshma Nayak, Ahmed Kamal & Syed F Adil
Pages: 873-883
Published online: 07 Mar 2016
AbstractforApoptosis inducing ability of silver decorated highly reduced graphene oxide nanocomposites in A549 lung cancer | Full Text | References | PDF (3.3 MB)
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Article
Simvastatin increases the antineoplastic actions of paclitaxel carried in lipid nanoemulsions in melanoma-bearing mice
Iara F Kretzer, Durvanei A Maria, Maria C Guido, Thaís C Contente & Raul C Maranhão
Pages: 885-904
Published online: 07 Mar 2016
AbstractforSimvastatin increases the antineoplastic actions of paclitaxel carried in lipid nanoemulsions in melanoma-bearing mice | Full Text | References | PDF (7.9 MB)
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Article
Effects of copper oxide nanoparticles on developing zebrafish embryos and larvae
Yan Sun, Gong Zhang, Zizi He, Yajie Wang, Jianlin Cui & Yuhao Li
Pages: 905-918
Published online: 07 Mar 2016
AbstractforEffects of copper oxide nanoparticles on developing zebrafish embryos and larvae | Full Text | References | PDF (4.6 MB)
  • 215 Views
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Article
Oxidative stress, inflammation, and DNA damage in multiple organs of mice acutely exposed to amorphous silica nanoparticles
Abderrahim Nemmar, Priya Yuvaraju, Sumaya Beegam, Javed Yasin, Elsadig E Kazzam & Badreldin H Ali
Pages: 919-928
Published online: 07 Mar 2016
AbstractforOxidative stress, inflammation, and DNA damage in multiple organs of mice acutely exposed to amorphous silica nanoparticles | Full Text | References | PDF (1.1 MB)
  • 124 Views
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Article
Effects of nanoparticle size on antitumor activity of 10-hydroxycamptothecin-conjugated gold nanoparticles: in vitro and in vivo studies
Hanmei Bao, Qing Zhang, Hui Xu & Zhao Yan
Pages: 929-940
Published online: 07 Mar 2016
AbstractforEffects of nanoparticle size on antitumor activity of 10-hydroxycamptothecin-conjugated gold nanoparticles: in vitro and in vivo studies | Full Text | References | PDF (4.4 MB)
  • 89 Views
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Article
A bio-artificial poly([d,l]-lactide-co-glycolide) drug-eluting nanofibrous periosteum for segmental long bone open fractures with significant periosteal stripping injuries
Ying-Chao Chou, Yi-Shiun Cheng, Yung-Heng Hsu, Yi-Hsun Yu & Shih-Jung Liu
Pages: 941-953
Published online: 08 Mar 2016
AbstractforA bio-artificial poly([d,l]-lactide-co-glycolide) drug-eluting nanofibrous periosteum for segmental long bone open fractures with significant periosteal stripping injuries | Full Text | References | PDF (6.2 MB)
  • 79 Views
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Article
Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody
Mesha Saeed, Mandy van Brakel, Sara Zalba, Erik Schooten, Joost AP Rens, Gerben A Koning, Reno Debets & Timo LM ten Hagen
Pages: 955-975
Published online: 08 Mar 2016
AbstractforTargeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody | Full Text | References | PDF (4.9 MB)
  • 69 Views
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Article
Antimicrobial performance of mesoporous titania thin films: role of pore size, hydrophobicity, and antibiotic release
Saba Atefyekta, Batur Ercan, Johan Karlsson, Erik Taylor, Stanley Chung, Thomas J Webster & Martin Andersson
Pages: 977-990
Published online: 10 Mar 2016
AbstractforAntimicrobial performance of mesoporous titania thin films: role of pore size, hydrophobicity, and antibiotic release | Full Text | References | PDF (5 MB)
  • 75 Views
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Article
Insights into the therapeutic potential of hypoxia-inducible factor-1α small interfering RNA in malignant melanoma delivered via folate-decorated cationic liposomes
Zhongjian Chen, Tianpeng Zhang, Baojian Wu & Xingwang Zhang
Pages: 991-1002
Published online: 28 Feb 2023
AbstractforInsights into the therapeutic potential of hypoxia-inducible factor-1α small interfering RNA in malignant melanoma delivered via folate-decorated cationic liposomes | Full Text | References | PDF (4.6 MB)
  • 63 Views
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Article
In vivo osseointegration of Ti implants with a strontium-containing nanotubular coating
Yonggang Dang, Li Zhang, Wen Song, Bei Chang, Tianxiao Han, Yumei Zhang & Lingzhou Zhao
Pages: 1003-1011
Published online: 14 Mar 2016
AbstractforIn vivo osseointegration of Ti implants with a strontium-containing nanotubular coating | Full Text | References | PDF (4.1 MB)
  • 72 Views
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Article
Spermine-modified Antheraea pernyi silk fibroin as a gene delivery carrier
Yanni Yu, Yongpei Hu, Xiufang Li, Yu Liu, Mingzhong Li, Jicheng Yang & Weihua Sheng
Pages: 1013-1023
Published online: 14 Mar 2016
AbstractforSpermine-modified Antheraea pernyi silk fibroin as a gene delivery carrier | Full Text | References | PDF (2.4 MB)
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Corrigendum

Correction
Photothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus–ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor [Corrigendum]
Page: 1025
Published online: 15 Mar 2016
CitationforPhotothermal treatment of liver cancer with albumin-conjugated gold nanoparticles initiates Golgi Apparatus–ER dysfunction and caspase-3 apoptotic pathway activation by selective targeting of Gp60 receptor [Corrigendum] | Full Text | PDF (94.5 KB)
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Original Research

Article
Colloidal nanocarriers for the enhanced cutaneous delivery of naftifine: characterization studies and in vitro and in vivo evaluations
M Sedef Erdal, Gül Özhan, M Cem Mat, Yıldız Özsoy & Sevgi Güngör
Pages: 1027-1037
Published online: 14 Mar 2016
AbstractforColloidal nanocarriers for the enhanced cutaneous delivery of naftifine: characterization studies and in vitro and in vivo evaluations | Full Text | References | PDF (1.4 MB)
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Article
Study of the combined treatment of lung cancer using gene-loaded immunomagnetic albumin nanospheres in vitro and in vivo
Hao Zhang, Chen Liang, Xinxin Hou, Ling Wang & Dongsheng Zhang
Pages: 1039-1050
Published online: 15 Mar 2016
AbstractforStudy of the combined treatment of lung cancer using gene-loaded immunomagnetic albumin nanospheres in vitro and in vivo | Full Text | References | PDF (3.7 MB)
  • 49 Views
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Article
One-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine
Jing-Wen Luo, Zhi-Rong Zhang, Tao Gong & Yao Fu
Pages: 1051-1065
Published online: 15 Mar 2016
AbstractforOne-step self-assembled nanomicelles for improving the oral bioavailability of nimodipine | Full Text | References | PDF (3.6 MB)
  • 59 Views
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Article
Aminoclay–lipid hybrid composite as a novel drug carrier of fenofibrate for the enhancement of drug release and oral absorption
Liang Yang, Yating Shao & Hyo-Kyung Han
Pages: 1067-1076
Published online: 15 Mar 2016
AbstractforAminoclay–lipid hybrid composite as a novel drug carrier of fenofibrate for the enhancement of drug release and oral absorption | Full Text | References | PDF (1.7 MB)
  • 71 Views
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Article
Docetaxel-loaded multilayer nanoparticles with nanodroplets for cancer therapy
Keun Sang Oh, Kyungim Kim, Byeong Deok Yoon, Hye Jin Lee, Dal Yong Park, Eun-yeong Kim, Kiho Lee, Jae Hong Seo & Soon Hong Yuk
Pages: 1077-1087
Published online: 16 Mar 2016
AbstractforDocetaxel-loaded multilayer nanoparticles with nanodroplets for cancer therapy | Full Text | References | PDF (3.2 MB)
  • 84 Views
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Article
A novel dissolution media for testing drug release from a nanostructured polysaccharide-based colon specific drug delivery system: an approach to alternative colon media
Niranjan G Kotla, Sima Singh, Balaji Maddiboyina, Omprakash Sunnapu & Thomas J Webster
Pages: 1089-1095
Published online: 17 Mar 2016
AbstractforA novel dissolution media for testing drug release from a nanostructured polysaccharide-based colon specific drug delivery system: an approach to alternative colon media | Full Text | References | PDF (1.1 MB)
  • 125 Views
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Article
Molecular magnetic resonance imaging of activated hepatic stellate cells with ultrasmall superparamagnetic iron oxide targeting integrin αvβ3 for staging liver fibrosis in rat model
Caiyuan Zhang, Huanhuan Liu, Yanfen Cui, Xiaoming Li, Zhongyang Zhang, Yong Zhang & Dengbin Wang
Pages: 1097-1108
Published online: 18 Mar 2016
AbstractforMolecular magnetic resonance imaging of activated hepatic stellate cells with ultrasmall superparamagnetic iron oxide targeting integrin αvβ3 for staging liver fibrosis in rat model | Full Text | References | PDF (7 MB)
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Article
Enhanced dissolution and oral absorption of tacrolimus by supersaturable self-emulsifying drug delivery system
Dae Ro Lee, Myoung Jin Ho, Hyuck Jun Jung, Ha Ra Cho, Jun Seo Park, Suk-Hyun Yoon, Yong Seok Choi, Young Wook Choi, Chung-Hun Oh & Myung Joo Kang
Pages: 1109-1117
Published online: 18 Mar 2016
AbstractforEnhanced dissolution and oral absorption of tacrolimus by supersaturable self-emulsifying drug delivery system | Full Text | References | PDF (1.2 MB)
  • 130 Views
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Article
Folic acid-targeted disulfide-based cross-linking micelle for enhanced drug encapsulation stability and site-specific drug delivery against tumors
Yumin Zhang, Junhui Zhou, Cuihong Yang, Weiwei Wang, Liping Chu, Fan Huang, Qiang Liu, Liandong Deng, Deling Kong, Jianfeng Liu & Jinjian Liu
Pages: 1119-1130
Published online: 18 Mar 2016
AbstractforFolic acid-targeted disulfide-based cross-linking micelle for enhanced drug encapsulation stability and site-specific drug delivery against tumors | Full Text | References | PDF (3.8 MB)
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Article
Destruction of vasculogenic mimicry channels by targeting epirubicin plus celecoxib liposomes in treatment of brain glioma
Rui-Jun Ju, Fan Zeng, Lei Liu, Li-Min Mu, Hong-Jun Xie, Yao Zhao, Yan Yan, Jia-Shuan Wu, Ying-Jie Hu & Wan-Liang Lu
Pages: 1131-1146
Published online: 21 Mar 2016
AbstractforDestruction of vasculogenic mimicry channels by targeting epirubicin plus celecoxib liposomes in treatment of brain glioma | Full Text | References | PDF (10.7 MB)
  • 73 Views
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Article
Sustained dual release of placental growth factor-2 and bone morphogenic protein-2 from heparin-based nanocomplexes for direct osteogenesis
Yun Liu, Li-Zhi Deng, Hai-Peng Sun, Jia-Yun Xu, Yi-Ming Li, Xin Xie, Li-Ming Zhang & Fei-Long Deng
Pages: 1147-1158
Published online: 22 Mar 2016
AbstractforSustained dual release of placental growth factor-2 and bone morphogenic protein-2 from heparin-based nanocomplexes for direct osteogenesis | Full Text | References | PDF (5.3 MB)
  • 81 Views
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Article
RETRACTED ARTICLE: Cerium oxide nanoparticles promote neurogenesis and abrogate hypoxia-induced memory impairment through AMPK–PKC–CBP signaling cascade
Aditya Arya, Anamika Gangwar, Sushil Kumar Singh, Manas Roy, Mainak Das, Niroj Kumar Sethy & Kalpana Bhargava
Pages: 1159-1173
Published online: 23 Mar 2016
AbstractforRETRACTED ARTICLE: Cerium oxide nanoparticles promote neurogenesis and abrogate hypoxia-induced memory impairment through AMPK–PKC–CBP signaling cascade | PDF (6 MB)
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Article
The efficiency of magnetic hyperthermia and in vivo histocompatibility for human-like collagen protein-coated magnetic nanoparticles
Le Chang, Xiao Li Liu, Dai Di Fan, Yu Qing Miao, Huan Zhang, He Ping Ma, Qiu Ying Liu, Pei Ma, Wei Ming Xue, Yan E Luo & Hai Ming Fan
Pages: 1175-1185
Published online: 23 Mar 2016
AbstractforThe efficiency of magnetic hyperthermia and in vivo histocompatibility for human-like collagen protein-coated magnetic nanoparticles | Full Text | References | PDF (4.5 MB)
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Review

Review Article
The preparation of metal–organic frameworks and their biomedical application
Rong Liu, Tian Yu, Zheng Shi & Zhiyong Wang
Pages: 1187-1200
Published online: 23 Mar 2016
AbstractforThe preparation of metal–organic frameworks and their biomedical application | Full Text | References | PDF (3.1 MB)
  • 391 Views
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Original Research

Article
Development of ibuprofen-loaded nanostructured lipid carrier-based gels: characterization and investigation of in vitro and in vivo penetration through the skin
Blanka Sütő, Szilvia Berkó, Gábor Kozma, Ákos Kukovecz, Mária Budai-Szűcs, Gábor Erős, Lajos Kemény, Anita Sztojkov-Ivanov, Róbert Gáspár & Erzsébet Csányi
Pages: 1201-1212
Published online: 30 Mar 2016
AbstractforDevelopment of ibuprofen-loaded nanostructured lipid carrier-based gels: characterization and investigation of in vitro and in vivo penetration through the skin | Full Text | References | PDF (2.3 MB)
  • 203 Views
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Article
Near-infrared fluorescence imaging platform for quantifying in vivo nanoparticle diffusion from drug loaded implants
Stacey Markovic, Jodi Belz, Rajiv Kumar, Robert A Cormack, Srinivas Sridhar & Mark Niedre
Pages: 1213-1223
Published online: 24 Mar 2016
AbstractforNear-infrared fluorescence imaging platform for quantifying in vivo nanoparticle diffusion from drug loaded implants | Full Text | References | PDF (2.8 MB)
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Review

Review Article
Nanomedicine developments in the treatment of metastatic pancreatic cancer: focus on nanoliposomal irinotecan
Andrew H Ko
Pages: 1225-1235
Published online: 28 Feb 2023
AbstractforNanomedicine developments in the treatment of metastatic pancreatic cancer: focus on nanoliposomal irinotecan | Full Text | References | PDF (238.8 KB)
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Original Research

Article
Improvement and enhancement of antibladder carcinoma cell effects of heteronemin by the nanosized hyaluronan aggregation
Han Hsiang Huang, Shyh Ming Kuo, Yi-Jhen Wu & Jui-Hsin Su
Pages: 1237-1251
Published online: 29 Mar 2016
AbstractforImprovement and enhancement of antibladder carcinoma cell effects of heteronemin by the nanosized hyaluronan aggregation | Full Text | References | PDF (6.5 MB)
  • 346 Views
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Article
Mechanistic investigation of toxicity of chromium oxide nanoparticles in murine fibrosarcoma cells
Saud Alarifi, Daoud Ali & Saad Alkahtani
Pages: 1253-1259
Published online: 29 Mar 2016
AbstractforMechanistic investigation of toxicity of chromium oxide nanoparticles in murine fibrosarcoma cells | Full Text | References | PDF (2.3 MB)
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Article
Novel therapeutic mechanisms determine the effectiveness of lipid-core nanocapsules on melanoma models
Carine C Drewes, Luana A Fiel, Celina G Bexiga, Ana Carolina C Asbahr, Mayara K Uchiyama, Bruno Cogliati, Koiti Araki, Sílvia S Guterres, Adriana R Pohlmann & Sandra P Farsky
Pages: 1261-1279
Published online: 31 Mar 2016
AbstractforNovel therapeutic mechanisms determine the effectiveness of lipid-core nanocapsules on melanoma models | Full Text | References | PDF (4.2 MB)
  • 102 Views
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Article
Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1
Enrique Vacas-Córdoba, Marek Maly, Francisco J De la Mata, Rafael Gómez, Marjorie Pion & Mª Ángeles Muñoz-Fernández
Pages: 1281-1294
Published online: 28 Feb 2023
AbstractforAntiviral mechanism of polyanionic carbosilane dendrimers against HIV-1 | Full Text | References | PDF (3.8 MB)
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Article
Nontoxic hydrophilic polymeric nanocomposites containing silver nanoparticles with strong antimicrobial activity
Alexander S Pozdnyakov, Artem I Emel’yanov, Nadezhda P Kuznetsova, Tamara G Ermakova, Tat’yana V Fadeeva, Larisa M Sosedova & Galina F Prozorova
Pages: 1295-1304
Published online: 31 Mar 2016
AbstractforNontoxic hydrophilic polymeric nanocomposites containing silver nanoparticles with strong antimicrobial activity | Full Text | References | PDF (3.1 MB)
  • 113 Views
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Article
Novel walnut peptide–selenium hybrids with enhanced anticancer synergism: facile synthesis and mechanistic investigation of anticancer activity
Wenzhen Liao, Rong Zhang, Chenbo Dong, Zhiqiang Yu & Jiaoyan Ren
Pages: 1305-1321
Published online: 11 Apr 2016
AbstractforNovel walnut peptide–selenium hybrids with enhanced anticancer synergism: facile synthesis and mechanistic investigation of anticancer activity | Full Text | References | PDF (4.6 MB)
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Article
Hyaluronic acid reagent functional chitosan-PEI conjugate with AQP2-siRNA suppressed endometriotic lesion formation
Meng-Dan Zhao, Jin-Lin Cheng, Jing-Jing Yan, Feng-Ying Chen, Jian-Zhong Sheng, Dong-Li Sun, Jian Chen, Jing Miao, Run-Ju Zhang, Cai-Hong Zheng & He-Feng Huang
Pages: 1323-1336
Published online: 30 Mar 2016
AbstractforHyaluronic acid reagent functional chitosan-PEI conjugate with AQP2-siRNA suppressed endometriotic lesion formation | Full Text | References | PDF (8.2 MB)
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Article
In vivo evaluation of an antibacterial coating containing halogenated furanone compound-loaded poly(l-lactic acid) nanoparticles on microarc-oxidized titanium implants
Yicheng Cheng, Bo Gao, Xianghui Liu, Xianghui Zhao, Weige Sun, Huifang Ren & Jiang Wu
Pages: 1337-1347
Published online: 30 Mar 2016
AbstractforIn vivo evaluation of an antibacterial coating containing halogenated furanone compound-loaded poly(l-lactic acid) nanoparticles on microarc-oxidized titanium implants | Full Text | References | PDF (7.9 MB)
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Article
Theranostic multimodular potential of zinc-doped ferrite-saturated metal-binding protein-loaded novel nanocapsules in cancers
Sishir K Kamalapuram, Rupinder K Kanwar, Kislay Roy, Rajneesh Chaudhary, Rakesh Sehgal & Jagat R Kanwar
Pages: 1349-1366
Published online: 28 Feb 2023
AbstractforTheranostic multimodular potential of zinc-doped ferrite-saturated metal-binding protein-loaded novel nanocapsules in cancers | Full Text | References | PDF (5.1 MB)
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Article
The role of well-defined nanotopography of titanium implants on osseointegration: cellular and molecular events in vivo
Dimitrios Karazisis, Ahmed M Ballo, Sarunas Petronis, Hossein Agheli, Lena Emanuelsson, Peter Thomsen & Omar Omar
Pages: 1367-1382
Published online: 28 Feb 2023
AbstractforThe role of well-defined nanotopography of titanium implants on osseointegration: cellular and molecular events in vivo | Full Text | References | PDF (12.4 MB)
  • 103 Views
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Article
Gelatin-methacrylamide gel loaded with microspheres to deliver GDNF in bilayer collagen conduit promoting sciatic nerve growth
Hai Zhuang, Shoushan Bu, Lei Hua, Mohammad A Darabi, Xiaojian Cao & Malcolm Xing
Pages: 1383-1394
Published online: 01 Apr 2016
AbstractforGelatin-methacrylamide gel loaded with microspheres to deliver GDNF in bilayer collagen conduit promoting sciatic nerve growth | Full Text | References | PDF (7.9 MB)
  • 141 Views
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Article
Folate receptor-targeted liposomes loaded with a diacid metabolite of norcantharidin enhance antitumor potency for H22 hepatocellular carcinoma both in vitro and in vivo
Min-Chen Liu, Lin Liu, Xia-Rong Wang, Wu-Ping Shuai, Ying Hu, Min Han & Jian-Qing Gao
Pages: 1395-1412
Published online: 04 Apr 2016
AbstractforFolate receptor-targeted liposomes loaded with a diacid metabolite of norcantharidin enhance antitumor potency for H22 hepatocellular carcinoma both in vitro and in vivo | Full Text | References | PDF (3.5 MB)
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Article
Hyaluronan-conjugated liposomes encapsulating gemcitabine for breast cancer stem cells
Na-Kyung Han, Dae Hwan Shin, Jung Seok Kim, Kwon Yeon Weon, Chang-Young Jang & Jin-Seok Kim
Pages: 1413-1425
Published online: 05 Apr 2016
AbstractforHyaluronan-conjugated liposomes encapsulating gemcitabine for breast cancer stem cells | Full Text | References | PDF (2.6 MB)
  • 126 Views
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Article
Cytoprotective effects of cerium and selenium nanoparticles on heat-shocked human dermal fibroblasts: an in vitro evaluation
Bo Yuan, Thomas J Webster & Amit K Roy
Pages: 1427-1433
Published online: 07 Apr 2016
AbstractforCytoprotective effects of cerium and selenium nanoparticles on heat-shocked human dermal fibroblasts: an in vitro evaluation | Full Text | References | PDF (5 MB)
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Article
Polyether ether ketone implants achieve increased bone fusion when coated with nano-sized hydroxyapatite: a histomorphometric study in rabbit bone
Pär Johansson, Ryo Jimbo, Yoshihito Naito, Per Kjellin, Fredrik Currie & Ann Wennerberg
Pages: 1435-1442
Published online: 06 Apr 2016
AbstractforPolyether ether ketone implants achieve increased bone fusion when coated with nano-sized hydroxyapatite: a histomorphometric study in rabbit bone | Full Text | References | PDF (5.1 MB)
  • 86 Views
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Article
Probing the nanoadhesion of Streptococcus sanguinis to titanium implant surfaces by atomic force microscopy
Sebastian Aguayo, Nikolaos Donos, Dave Spratt & Laurent Bozec
Pages: 1443-1450
Published online: 06 Apr 2016
AbstractforProbing the nanoadhesion of Streptococcus sanguinis to titanium implant surfaces by atomic force microscopy | Full Text | References | PDF (1.6 MB)
  • 78 Views
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Article
Novel in situ self-assembly nanoparticles for formulating a poorly water-soluble drug in oral solid granules, improving stability, palatability, and bioavailability
Shujie Guo, Kevin Pham, Diana Li, Scott R Penzak & Xiaowei Dong
Pages: 1451-1460
Published online: 07 Apr 2016
AbstractforNovel in situ self-assembly nanoparticles for formulating a poorly water-soluble drug in oral solid granules, improving stability, palatability, and bioavailability | Full Text | References | PDF (1.3 MB)
  • 83 Views
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Article
Evaluation of adipose-derived stem cells for tissue-engineered muscle repair construct-mediated repair of a murine model of volumetric muscle loss injury
Venu Kesireddy
Pages: 1461-1473
Published online: 08 Apr 2016
AbstractforEvaluation of adipose-derived stem cells for tissue-engineered muscle repair construct-mediated repair of a murine model of volumetric muscle loss injury | Full Text | References | PDF (7 MB)
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Article
The role of surfactants in the formulation of elastic liposomal gels containing a synthetic opioid analgesic
Sima Singh, Harsh Vardhan, Niranjan G Kotla, Balaji Maddiboyina, Dinesh Sharma & Thomas J Webster
Pages: 1475-1482
Published online: 08 Apr 2016
AbstractforThe role of surfactants in the formulation of elastic liposomal gels containing a synthetic opioid analgesic | Full Text | References | PDF (2 MB)
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Article
Electrospun silk fibroin/poly(lactide-co-ε-caprolactone) nanofibrous scaffolds for bone regeneration
Zi Wang, Ming Lin, Qing Xie, Hao Sun, Yazhuo Huang, DanDan Zhang, Zhang Yu, Xiaoping Bi, Junzhao Chen, Jing Wang, Wodong Shi, Ping Gu & Xianqun Fan
Pages: 1483-1500
Published online: 28 Feb 2023
AbstractforElectrospun silk fibroin/poly(lactide-co-ε-caprolactone) nanofibrous scaffolds for bone regeneration | Full Text | References | PDF (5.3 MB)
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Article
Nicotinamide polymeric nanoemulsified systems: a quality-by-design case study for a sustained antimicrobial activity
Ahmed S Zidan, Osama AA Ahmed & Bader M Aljaeid
Pages: 1501-1516
Published online: 12 Apr 2016
AbstractforNicotinamide polymeric nanoemulsified systems: a quality-by-design case study for a sustained antimicrobial activity | Full Text | References | PDF (2.2 MB)
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Article
Labeling of mesenchymal stem cells for MRI with single-cell sensitivity
Angela Ariza de Schellenberger, Harald Kratz, Tracy D Farr, Norbert Löwa, Ralf Hauptmann, Susanne Wagner, Matthias Taupitz, Jörg Schnorr & Eyk A Schellenberger
Pages: 1517-1535
Published online: 28 Feb 2023
AbstractforLabeling of mesenchymal stem cells for MRI with single-cell sensitivity | Full Text | References | PDF (6.5 MB)
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Article
A reduced graphene oxide-based fluorescence resonance energy transfer sensor for highly sensitive detection of matrix metalloproteinase 2
Gaina Xi, Xiaoping Wang & Tongsheng Chen
Pages: 1537-1547
Published online: 28 Feb 2023
AbstractforA reduced graphene oxide-based fluorescence resonance energy transfer sensor for highly sensitive detection of matrix metalloproteinase 2 | Full Text | References | PDF (3.2 MB)
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Article
Improving proton therapy by metal-containing nanoparticles: nanoscale insights
Thomas Schlathölter, Pierre Eustache, Erika Porcel, Daniela Salado, Lenka Stefancikova, Olivier Tillement, Francois Lux, Pierre Mowat, Aleksandra K Biegun, Marc-Jan van Goethem, Hynd Remita & Sandrine Lacombe
Pages: 1549-1556
Published online: 28 Feb 2023
AbstractforImproving proton therapy by metal-containing nanoparticles: nanoscale insights | Full Text | References | PDF (798.6 KB)
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Article
Development and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo pharmacokinetic study
Ling-Chun Chen, Ying-Chen Chen, Chia-Yu Su, Chung-Shu Hong, Hsiu-O Ho & Ming-Thau Sheu
Pages: 1557-1566
Published online: 15 Apr 2016
AbstractforDevelopment and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo pharmacokinetic study | Full Text | References | PDF (1.8 MB)
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Article
Engineered metal nanoparticles in the sub-nanomolar levels kill cancer cells
Vitaly Vodyanoy, Yasmine Daniels, Oleg Pustovyy, William A MacCrehan, Shin Muramoto & Gheorghe Stan
Pages: 1567-1576
Published online: 18 Apr 2016
AbstractforEngineered metal nanoparticles in the sub-nanomolar levels kill cancer cells | Full Text | References | PDF (1.7 MB)
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Article
Potential antitumor activity of novel DODAC/PHO-S liposomes
Arthur Cássio de Lima Luna, Greice Kelle Viegas Saraiva, Otaviano Mendonça Ribeiro Filho, Gilberto Orivaldo Chierice, Salvador Claro Neto, Iolanda Midea Cuccovia & Durvanei Augusto Maria
Pages: 1577-1591
Published online: 18 Apr 2016
AbstractforPotential antitumor activity of novel DODAC/PHO-S liposomes | Full Text | References | PDF (4.4 MB)
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Article
Polyacrylate/nanosilica causes pleural and pericardial effusion, and pulmonary fibrosis and granuloma in rats similar to those observed in exposed workers
Xiaoli Zhu, Wen Cao, Bing Chang, Linyuan Zhang, Peihuan Qiao, Xue Li, Lifang Si, Yingmei Niu & Yuguo Song
Pages: 1593-1605
Published online: 18 Apr 2016
AbstractforPolyacrylate/nanosilica causes pleural and pericardial effusion, and pulmonary fibrosis and granuloma in rats similar to those observed in exposed workers | Full Text | References | PDF (5.8 MB)
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Article
Conjugation of insulin onto the sidewalls of single-walled carbon nanotubes through functionalization and diimide-activated amidation
Chee Meng Ng, Hwei-San Loh, Kasturi Muthoosamy, Nanthini Sridewi & Sivakumar Manickam
Pages: 1607-1614
Published online: 18 Apr 2016
AbstractforConjugation of insulin onto the sidewalls of single-walled carbon nanotubes through functionalization and diimide-activated amidation | Full Text | References | PDF (1.8 MB)
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Article
Design of acid-responsive polymeric nanoparticles for 7,3′,4′-trihydroxyisoflavone topical administration
Pao-Hsien Huang, Stephen Chu-Sung Hu, Chiang-Wen Lee, An-Chi Yeh, Chih-Hua Tseng & Feng-Lin Yen
Pages: 1615-1627
Published online: 28 Feb 2023
AbstractforDesign of acid-responsive polymeric nanoparticles for 7,3′,4′-trihydroxyisoflavone topical administration | Full Text | References | PDF (3.6 MB)
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Article
RETRACTED ARTICLE: c(RGDyK)-decorated Pluronic micelles for enhanced doxorubicin and paclitaxel delivery to brain glioma
YuKun Huang, Wenchao Liu, Feng Gao, Xiaoling Fang & Yanzuo Chen
Pages: 1629-1641
Published online: 19 Apr 2016
AbstractforRETRACTED ARTICLE: c(RGDyK)-decorated Pluronic micelles for enhanced doxorubicin and paclitaxel delivery to brain glioma | PDF (4.9 MB)
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Article
Matrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation
Xiaoyan Zhang, Xiaofei Wang, Weitong Zhong, Xiaoqing Ren, Xianyi Sha & Xiaoling Fang
Pages: 1643-1661
Published online: 22 Apr 2016
AbstractforMatrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation | Full Text | References | PDF (2.8 MB)
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Article
Biomimetic synthesis of antimicrobial silver nanoparticles using in vitro-propagated plantlets of a medicinally important endangered species: Phlomis bracteosa
Sumaira Anjum & Bilal Haider Abbasi
Pages: 1663-1675
Published online: 22 Apr 2016
AbstractforBiomimetic synthesis of antimicrobial silver nanoparticles using in vitro-propagated plantlets of a medicinally important endangered species: Phlomis bracteosa | Full Text | References | PDF (4 MB)
  • 154 Views
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Article
Synthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy
Jing Xie, Xiaomin Zhang, Meiyu Teng, Bo Yu, Shuang Yang, Robert J Lee & Lesheng Teng
Pages: 1677-1686
Published online: 26 Apr 2016
AbstractforSynthesis, characterization, and evaluation of mPEG–SN38 and mPEG–PLA–SN38 micelles for cancer therapy | Full Text | References | PDF (3.1 MB)
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Article
Development and evaluation of vitamin E d-α-tocopheryl polyethylene glycol 1000 succinate-mixed polymeric phospholipid micelles of berberine as an anticancer nanopharmaceutical
Roger Shen, Jane J Kim, Mingyi Yao & Tamer A Elbayoumi
Pages: 1687-1700
Published online: 26 Apr 2016
AbstractforDevelopment and evaluation of vitamin E d-α-tocopheryl polyethylene glycol 1000 succinate-mixed polymeric phospholipid micelles of berberine as an anticancer nanopharmaceutical | Full Text | References | PDF (2 MB)
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Article
Oxidative stress response in neural stem cells exposed to different superparamagnetic iron oxide nanoparticles
Igor M Pongrac, Ivan Pavičić, Mirta Milić, Lada Brkić Ahmed, Michal Babič, Daniel Horák, Ivana Vinković Vrček & Srećko Gajović
Pages: 1701-1715
Published online: 26 Apr 2016
AbstractforOxidative stress response in neural stem cells exposed to different superparamagnetic iron oxide nanoparticles | Full Text | References | PDF (2 MB)
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Article
The effect of insulin-loaded linear poly(ethylene glycol)-brush-like poly(l-lysine) block copolymer on renal ischemia/reperfusion-induced lung injury through downregulating hypoxia-inducible factor
Fei Tong, Xiangyuan Tang, Xin Li, Wenquan Xia & Daojun Liu
Pages: 1717-1730
Published online: 27 Apr 2016
AbstractforThe effect of insulin-loaded linear poly(ethylene glycol)-brush-like poly(l-lysine) block copolymer on renal ischemia/reperfusion-induced lung injury through downregulating hypoxia-inducible factor | Full Text | References | PDF (1.4 MB)
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Article
Effects of the iron oxide nanoparticle Molday ION Rhodamine B on the viability and regenerative function of neural stem cells: relevance to clinical translation
Abhishek Umashankar, Mandi J Corenblum, Sneha Ray, Michel Valdez, Eriko S Yoshimaru, Theodore P Trouard & Lalitha Madhavan
Pages: 1731-1748
Published online: 27 Apr 2016
AbstractforEffects of the iron oxide nanoparticle Molday ION Rhodamine B on the viability and regenerative function of neural stem cells: relevance to clinical translation | Full Text | References | PDF (8.3 MB)
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Article
In vitro and in vivo antimicrobial activity of combined therapy of silver nanoparticles and visible blue light against Pseudomonas aeruginosa
Suzanne Nour El Din, Tarek A El-Tayeb, Khaled Abou-Aisha & Mohamed El-Azizi
Pages: 1749-1758
Published online: 27 Apr 2016
AbstractforIn vitro and in vivo antimicrobial activity of combined therapy of silver nanoparticles and visible blue light against Pseudomonas aeruginosa | Full Text | References | PDF (1.8 MB)
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Article
Manganese dioxide nanosheets-based redox/pH-responsive drug delivery system for cancer theranostic application
Yongwei Hao, Lei Wang, Bingxiang Zhang, Dong Li, Dehui Meng, Jinjin Shi, Hongling Zhang, Zhenzhong Zhang & Yun Zhang
Pages: 1759-1778
Published online: 29 Apr 2016
AbstractforManganese dioxide nanosheets-based redox/pH-responsive drug delivery system for cancer theranostic application | Full Text | References | PDF (6.2 MB)
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Article
Hyperthermia mediated by dextran-coated La0.7Sr0.3MnO3 nanoparticles: in vivo studies
Reihaneh Haghniaz, Rinku D Umrani & Kishore M Paknikar
Pages: 1779-1791
Published online: 27 Apr 2016
AbstractforHyperthermia mediated by dextran-coated La0.7Sr0.3MnO3 nanoparticles: in vivo studies | Full Text | References | PDF (4.5 MB)
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Article
Hydrophilic mesoporous carbon nanospheres with high drug-loading efficiency for doxorubicin delivery and cancer therapy
Huan Wang, Xiangui Li, Zhiqiang Ma, Dan Wang, Linzhao Wang, Jieqiong Zhan, Lan She & Feng Yang
Pages: 1793-1806
Published online: 27 Apr 2016
AbstractforHydrophilic mesoporous carbon nanospheres with high drug-loading efficiency for doxorubicin delivery and cancer therapy | Full Text | References | PDF (4.1 MB)
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Article
Initial study of sediment antagonism and characteristics of silver nanoparticle-coated biliary stents in an experimental animal model
Yigeng Tian, Mingfeng Xia, Shuai Zhang, Zhen Fu, Qingbin Wen, Feng Liu, Zongzhen Xu, Tao Li & Hu Tian
Pages: 1807-1817
Published online: 28 Apr 2016
AbstractforInitial study of sediment antagonism and characteristics of silver nanoparticle-coated biliary stents in an experimental animal model | Full Text | References | PDF (5.2 MB)
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Article
Facile synthesis of soybean phospholipid-encapsulated MoS2 nanosheets for efficient in vitro and in vivo photothermal regression of breast tumor
Xiang Li, Yun Gong, Xiaoqian Zhou, Hui Jin, Huanhuan Yan, Shige Wang & Jun Liu
Pages: 1819-1833
Published online: 29 Apr 2016
AbstractforFacile synthesis of soybean phospholipid-encapsulated MoS2 nanosheets for efficient in vitro and in vivo photothermal regression of breast tumor | Full Text | References | PDF (7.7 MB)
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Article
Phytosynthesis of silver nanoparticles using Artemisia marschalliana Sprengel aerial part extract and assessment of their antioxidant, anticancer, and antibacterial properties
Soheil Salehi, Seyed Ataollah Sadat Shandiz, Farinaz Ghanbar, Mohammad Raouf Darvish, Mehdi Shafiee Ardestani, Amir Mirzaie & Mohsen Jafari
Pages: 1835-1846
Published online: 29 Apr 2016
AbstractforPhytosynthesis of silver nanoparticles using Artemisia marschalliana Sprengel aerial part extract and assessment of their antioxidant, anticancer, and antibacterial properties | Full Text | References | PDF (2.8 MB)
  • 238 Views
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Article
Capturing and concentrating adenovirus using magnetic anionic nanobeads
Akikazu Sakudo, Koichi Baba & Kazuyoshi Ikuta
Pages: 1847-1857
Published online: 09 May 2016
AbstractforCapturing and concentrating adenovirus using magnetic anionic nanobeads | Full Text | References | PDF (2.1 MB)
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Article
Voltammetric determination of melatonin using a graphene-based sensor in pharmaceutical products
Irina Mirela Apetrei & Constantin Apetrei
Pages: 1859-1866
Published online: 02 May 2016
AbstractforVoltammetric determination of melatonin using a graphene-based sensor in pharmaceutical products | Full Text | References | PDF (1.5 MB)
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Article
Enhancing the in vivo transdermal delivery of gold nanoparticles using poly(ethylene glycol) and its oleylamine conjugate
Pa Fan Hsiao, Sydney Peng, Ting-Cheng Tang, Shuian-Yin Lin & Hsieh-Chih Tsai
Pages: 1867-1878
Published online: 28 Feb 2023
AbstractforEnhancing the in vivo transdermal delivery of gold nanoparticles using poly(ethylene glycol) and its oleylamine conjugate | Full Text | References | PDF (3.5 MB)
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Article
Effects of green-synthesized silver nanoparticles on lung cancer cells in vitro and grown as xenograft tumors in vivo
Yan He, Zhiyun Du, Shijing Ma, Yue Liu, Dongli Li, Huarong Huang, Sen Jiang, Shupeng Cheng, Wenjing Wu, Kun Zhang & Xi Zheng
Pages: 1879-1887
Published online: 04 May 2016
AbstractforEffects of green-synthesized silver nanoparticles on lung cancer cells in vitro and grown as xenograft tumors in vivo | Full Text | References | PDF (3.4 MB)
  • 413 Views
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Article
Phytogenic silver, gold, and bimetallic nanoparticles as novel antitubercular agents
Richa Singh, Laxman Nawale, Manisha Arkile, Sweety Wadhwani, Utkarsha Shedbalkar, Snehal Chopade, Dhiman Sarkar & Balu Ananda Chopade
Pages: 1889-1897
Published online: 04 May 2016
AbstractforPhytogenic silver, gold, and bimetallic nanoparticles as novel antitubercular agents | Full Text | References | PDF (735 KB)
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Article
Biosynthesis of silver nanoparticles by the fungus Arthroderma fulvum and its antifungal activity against genera of Candida, Aspergillus and Fusarium
Baiji Xue, Dan He, Song Gao, Dongyang Wang, Koji Yokoyama & Li Wang
Pages: 1899-1906
Published online: 04 May 2016
AbstractforBiosynthesis of silver nanoparticles by the fungus Arthroderma fulvum and its antifungal activity against genera of Candida, Aspergillus and Fusarium | Full Text | References | PDF (1.9 MB)
  • 269 Views
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Article
Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3
Yin-Jieh Tsai & Bing-Huei Chen
Pages: 1907-1926
Published online: 06 May 2016
AbstractforPreparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3 | Full Text | References | PDF (1.9 MB)
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Review

Review Article
Synthesis, toxicity, biocompatibility, and biomedical applications of graphene and graphene-related materials
Sangiliyandi Gurunathan & Jin-Hoi Kim
Pages: 1927-1945
Published online: 05 May 2016
AbstractforSynthesis, toxicity, biocompatibility, and biomedical applications of graphene and graphene-related materials | Full Text | References | PDF (2.1 MB)
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Original Research

Article
Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis
Hong Zou, Li Li, Ines Garcia Carcedo, Zhi Ping Xu, Michael Monteiro & Wenyi Gu
Pages: 1947-1958
Published online: 05 May 2016
AbstractforSynergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/mTOR dual inhibitor BEZ235 through apoptosis | Full Text | References | PDF (2.4 MB)
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Article
Downregulation of B-cell lymphoma/leukemia-2 by overexpressed microRNA 34a enhanced titanium dioxide nanoparticle-induced autophagy in BEAS-2B cells
Wenlin Bai, Yujiao Chen, Pengling Sun & Ai Gao
Pages: 1959-1971
Published online: 06 May 2016
AbstractforDownregulation of B-cell lymphoma/leukemia-2 by overexpressed microRNA 34a enhanced titanium dioxide nanoparticle-induced autophagy in BEAS-2B cells | Full Text | References | PDF (6.3 MB)
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Article
Hyperthermia treatment of tumors by mesenchymal stem cell-delivered superparamagnetic iron oxide nanoparticles
Tammy L Kalber, Katherine L Ordidge, Paul Southern, Michael R Loebinger, Panagiotis G Kyrtatos, Quentin A Pankhurst, Mark F Lythgoe & Sam M Janes
Pages: 1973-1983
Published online: 09 May 2016
AbstractforHyperthermia treatment of tumors by mesenchymal stem cell-delivered superparamagnetic iron oxide nanoparticles | Full Text | References | PDF (2.3 MB)
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Corrigendum

Correction
Enhanced detection of single-cell-secreted proteins using a fluorescent immunoassay on the protein-G-terminated glass substrate [Corrigendum]
Page: 1985
Published online: 11 May 2016
CitationforEnhanced detection of single-cell-secreted proteins using a fluorescent immunoassay on the protein-G-terminated glass substrate [Corrigendum] | Full Text | PDF (144 KB)
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Review

Review Article
Current application of phytocompound-based nanocosmeceuticals for beauty and skin therapy
Palanivel Ganesan & Dong-Kug Choi
Pages: 1987-2007
Published online: 11 May 2016
AbstractforCurrent application of phytocompound-based nanocosmeceuticals for beauty and skin therapy | Full Text | References | PDF (678.7 KB)
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Original Research

Article
Transportan in nanocarriers improves skin localization and antitumor activity of paclitaxel
Dominique Pepe, Vanessa FM Carvalho, Melissa McCall, Débora P de Lemos & Luciana B Lopes
Pages: 2009-2019
Published online: 11 May 2016
AbstractforTransportan in nanocarriers improves skin localization and antitumor activity of paclitaxel | Full Text | References | PDF (1,016.9 KB)
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Article
Doxorubicin-modified magnetic nanoparticles as a drug delivery system for magnetic resonance imaging-monitoring magnet-enhancing tumor chemotherapy
Po-Chin Liang, Yung-Chu Chen, Chi-Feng Chiang, Lein-Ray Mo, Shwu-Yuan Wei, Wen-Yuan Hsieh & Win-Li Lin
Pages: 2021-2037
Published online: 12 May 2016
AbstractforDoxorubicin-modified magnetic nanoparticles as a drug delivery system for magnetic resonance imaging-monitoring magnet-enhancing tumor chemotherapy | Full Text | References | PDF (4.2 MB)
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Article
Carbon nanospheres mediated delivery of nuclear matrix protein SMAR1 to direct experimental autoimmune encephalomyelitis in mice
Sijo V Chemmannur, Prasad Bhagat, Bhalchandra Mirlekar, Kishore M Paknikar & Samit Chattopadhyay
Pages: 2039-2051
Published online: 12 May 2016
AbstractforCarbon nanospheres mediated delivery of nuclear matrix protein SMAR1 to direct experimental autoimmune encephalomyelitis in mice | Full Text | References | PDF (2.4 MB)
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Article
Synergistic intrafibrillar/extrafibrillar mineralization of collagen scaffolds based on a biomimetic strategy to promote the regeneration of bone defects
Yao Wang, Ngo Van Manh, Haorong Wang, Xue Zhong, Xu Zhang & Changyi Li
Pages: 2053-2067
Published online: 12 May 2016
AbstractforSynergistic intrafibrillar/extrafibrillar mineralization of collagen scaffolds based on a biomimetic strategy to promote the regeneration of bone defects | Full Text | References | PDF (8.8 MB)
  • 112 Views
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Article
Cellular uptake and fate of fibroin microspheres loaded with randomly fragmented DNA in 3T3 cells
Jin Sil Lee & Won Hur
Pages: 2069-2079
Published online: 13 May 2016
AbstractforCellular uptake and fate of fibroin microspheres loaded with randomly fragmented DNA in 3T3 cells | Full Text | References | PDF (4.1 MB)
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Article
Long-term effect of ropivacaine nanoparticles for sciatic nerve block on postoperative pain in rats
Zi Wang, Haizhen Huang, Shaozhong Yang, Shanshan Huang, Jingxuan Guo, Qi Tang & Feng Qi
Pages: 2081-2090
Published online: 17 May 2016
AbstractforLong-term effect of ropivacaine nanoparticles for sciatic nerve block on postoperative pain in rats | Full Text | References | PDF (10.8 MB)
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Article
Improving the osteogenesis of human bone marrow mesenchymal stem cell sheets by microRNA-21-loaded chitosan/hyaluronic acid nanoparticles via reverse transfection
Zhongshan Wang, Guangsheng Wu, Mengying Wei, Qian Liu, Jian Zhou, Tian Qin, Xiaoke Feng, Huan Liu, Zhihong Feng & Yimin Zhao
Pages: 2091-2105
Published online: 17 May 2016
AbstractforImproving the osteogenesis of human bone marrow mesenchymal stem cell sheets by microRNA-21-loaded chitosan/hyaluronic acid nanoparticles via reverse transfection | Full Text | References | PDF (8.4 MB)
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Review

Review Article
Current status and perspectives in atomic force microscopy-based identification of cellular transformation
Chenbo Dong, Xiao Hu & Cerasela Zoica Dinu
Pages: 2107-2118
Published online: 28 Feb 2023
AbstractforCurrent status and perspectives in atomic force microscopy-based identification of cellular transformation | Full Text | References | PDF (3.5 MB)
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Original Research

Article
A novel paclitaxel-loaded poly(d,l-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment
Xun Yuan, Wenxiang Ji, Si Chen, Yuling Bao, Songwei Tan, Shun Lu, Kongming Wu & Qian Chu
Pages: 2119-2131
Published online: 25 May 2016
AbstractforA novel paclitaxel-loaded poly(d,l-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment | Full Text | References | PDF (5.1 MB)
  • 124 Views
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Article
Aptamer–polymer functionalized silicon nanosubstrates for enhanced recovered circulating tumor cell viability and in vitro chemosensitivity testing
Qinglin Shen, Caixia Peng, Yan Zhan, Liang Fan, Mengyi Wang, Qing Zhou, Jue Liu, Xiaojuan Lv, Qiu Tang, Jun Li, Xiaodong Huang & Jiahong Xia
Pages: 2133-2146
Published online: 18 May 2016
AbstractforAptamer–polymer functionalized silicon nanosubstrates for enhanced recovered circulating tumor cell viability and in vitro chemosensitivity testing | Full Text | References | PDF (5.3 MB)
  • 58 Views
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Article
Prevention of vaginal and rectal herpes simplex virus type 2 transmission in mice: mechanism of antiviral action
Rafael Ceña-Diez, Enrique Vacas-Córdoba, Pilar García-Broncano, FJ de la Mata, Rafael Gómez, Marek Maly & Mª Ángeles Muñoz-Fernández
Pages: 2147-2162
Published online: 19 May 2016
AbstractforPrevention of vaginal and rectal herpes simplex virus type 2 transmission in mice: mechanism of antiviral action | Full Text | References | PDF (2 MB)
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Article
Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions
Ryan A Ortega, Whitney Barham, Kavya Sharman, Oleg Tikhomirov, Todd D Giorgio & Fiona E Yull
Pages: 2163-2177
Published online: 18 May 2016
AbstractforManipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions | Full Text | References | PDF (1.3 MB)
  • 93 Views
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Article
Vesicular (liposomal and nanoparticulated) delivery of curcumin: a comparative study on carbon tetrachloride–mediated oxidative hepatocellular damage in rat model
Somsubhra Thakur Choudhury, Nirmalendu Das, Swarupa Ghosh, Debasree Ghosh, Somsuta Chakraborty & Nahid Ali
Pages: 2179-2193
Published online: 18 May 2016
AbstractforVesicular (liposomal and nanoparticulated) delivery of curcumin: a comparative study on carbon tetrachloride–mediated oxidative hepatocellular damage in rat model | Full Text | References | PDF (5.4 MB)
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Article
In vitro and in vivo targeting imaging of pancreatic cancer using a Fe3O4@SiO2 nanoprobe modified with anti-mesothelin antibody
Fang Liu, Wenjun Le, Tianxiao Mei, Tiegong Wang, Luguang Chen, Yi Lei, Shaobin Cui, Bingdi Chen, Zheng Cui & Chengwei Shao
Pages: 2195-2207
Published online: 19 May 2016
AbstractforIn vitro and in vivo targeting imaging of pancreatic cancer using a Fe3O4@SiO2 nanoprobe modified with anti-mesothelin antibody | Full Text | References | PDF (4.3 MB)
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Article
The relevancy of controlled nanocrystallization on rifampicin characteristics and cytotoxicity
Salma M Mohyeldin, Mohammed M Mehanna & Nazik A Elgindy
Pages: 2209-2222
Published online: 19 May 2016
AbstractforThe relevancy of controlled nanocrystallization on rifampicin characteristics and cytotoxicity | Full Text | References | PDF (1.1 MB)
  • 112 Views
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Article
In vivo evaluation of the anti-infection potential of gentamicin-loaded nanotubes on titania implants
Ying Yang, Hai-yong Ao, Sheng-bing Yang, Yu-gang Wang, Wen-tao Lin, Zhi-feng Yu & Ting-ting Tang
Pages: 2223-2234
Published online: 19 May 2016
AbstractforIn vivo evaluation of the anti-infection potential of gentamicin-loaded nanotubes on titania implants | Full Text | References | PDF (5.5 MB)
  • 113 Views
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Article
Development of octreotide-conjugated polymeric prodrug of bufalin for targeted delivery to somatostatin receptor 2 overexpressing breast cancer in vitro and in vivo
Tao Liu, Tingting Jia, Xia Yuan, Cheng Liu, Jian Sun, Zhenhua Ni, Jian Xu, Xuhui Wang & Yi Yuan
Pages: 2235-2250
Published online: 23 May 2016
AbstractforDevelopment of octreotide-conjugated polymeric prodrug of bufalin for targeted delivery to somatostatin receptor 2 overexpressing breast cancer in vitro and in vivo | Full Text | References | PDF (3.1 MB)
  • 66 Views
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Article
Silica nanoparticles induce reversible damage of spermatogenic cells via RIPK1 signal pathways in C57 mice
Lihua Ren, Jin Zhang, Yang Zou, Lianshuang Zhang, Jialiu Wei, Zhixiong Shi, Yanbo Li, Caixia Guo, Zhiwei Sun & Xianqing Zhou
Pages: 2251-2264
Published online: 24 May 2016
AbstractforSilica nanoparticles induce reversible damage of spermatogenic cells via RIPK1 signal pathways in C57 mice | Full Text | References | PDF (7.2 MB)
  • 79 Views
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Article
Graphene oxide scaffold accelerates cellular proliferative response and alveolar bone healing of tooth extraction socket
Erika Nishida, Hirofumi Miyaji, Akihito Kato, Hiroko Takita, Toshihiko Iwanaga, Takehito Momose, Kosuke Ogawa, Shusuke Murakami, Tsutomu Sugaya & Masamitsu Kawanami
Pages: 2265-2277
Published online: 24 May 2016
AbstractforGraphene oxide scaffold accelerates cellular proliferative response and alveolar bone healing of tooth extraction socket | Full Text | References | PDF (5.7 MB)
  • 134 Views
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Review

Review Article
Ethosomal nanocarriers: the impact of constituents and formulation techniques on ethosomal properties, in vivo studies, and clinical trials
Ibrahim M Abdulbaqi, Yusrida Darwis, Nurzalina Abdul Karim Khan, Reem Abou Assi & Arshad A Khan
Pages: 2279-2304
Published online: 25 May 2016
AbstractforEthosomal nanocarriers: the impact of constituents and formulation techniques on ethosomal properties, in vivo studies, and clinical trials | Full Text | References | PDF (3.6 MB)
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Original Research

Article
Polarity-sensitive nanocarrier for oral delivery of Sb(V) and treatment of cutaneous leishmaniasis
Juliane S Lanza, Flaviana R Fernandes, José D Corrêa-Júnior, José MC Vilela, Rogério Magalhães-Paniago, Lucas AM Ferreira, Margareth S Andrade, Cynthia Demicheli, Maria N Melo & Frédéric Frézard
Pages: 2305-2318
Published online: 25 May 2016
AbstractforPolarity-sensitive nanocarrier for oral delivery of Sb(V) and treatment of cutaneous leishmaniasis | Full Text | References | PDF (3.5 MB)
  • 49 Views
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Article
Time-dependent toxicity of cadmium telluride quantum dots on liver and kidneys in mice: histopathological changes with elevated free cadmium ions and hydroxyl radicals
Mengmeng Wang, Jilong Wang, Hubo Sun, Sihai Han, Shuai Feng, Lu Shi, Peijun Meng, Jiayi Li, Peili Huang & Zhiwei Sun
Pages: 2319-2328
Published online: 25 May 2016
AbstractforTime-dependent toxicity of cadmium telluride quantum dots on liver and kidneys in mice: histopathological changes with elevated free cadmium ions and hydroxyl radicals | Full Text | References | PDF (2.7 MB)
  • 72 Views
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Article
In vivo biodistribution, biocompatibility, and efficacy of sorafenib-loaded lipid-based nanosuspensions evaluated experimentally in cancer
Shaomei Yang, Bo Zhang, Xiaowei Gong, Tianqi Wang, Yongjun Liu & Na Zhang
Pages: 2329-2343
Published online: 25 May 2016
AbstractforIn vivo biodistribution, biocompatibility, and efficacy of sorafenib-loaded lipid-based nanosuspensions evaluated experimentally in cancer | Full Text | References | PDF (5.2 MB)
  • 153 Views
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Article
Rationally designed nanocarriers for intranasaltherapy of allergic rhinitis: influence of carrier type on in vivo nasal deposition
Marwa Ahmed Sallam, Hala Mahmoud Helal & Sana Mohamed Mortada
Pages: 2345-2357
Published online: 25 May 2016
AbstractforRationally designed nanocarriers for intranasaltherapy of allergic rhinitis: influence of carrier type on in vivo nasal deposition | Full Text | References | PDF (3 MB)
  • 88 Views
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Article
Preparation of liposomal amiodarone and investigation of its cardiomyocyte-targeting ability in cardiac radiofrequency ablation rat model
Ying Zhuge, Zhi-Feng Zheng, Mu-Qing Xie, Lin Li, Fang Wang & Feng Gao
Pages: 2359-2367
Published online: 28 Feb 2023
AbstractforPreparation of liposomal amiodarone and investigation of its cardiomyocyte-targeting ability in cardiac radiofrequency ablation rat model | Full Text | References | PDF (1.5 MB)
  • 77 Views
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Article
Ethyl cellulose nanoparticles as a platform to decrease ulcerogenic potential of piroxicam: formulation and in vitro/in vivo evaluation
Salma E El-Habashy, Ahmed N Allam & Amal H El-Kamel
Pages: 2369-2380
Published online: 26 May 2016
AbstractforEthyl cellulose nanoparticles as a platform to decrease ulcerogenic potential of piroxicam: formulation and in vitro/in vivo evaluation | Full Text | References | PDF (3.8 MB)
  • 151 Views
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Article
Comprehensive evaluation of carboxylated nanodiamond as a topical drug delivery system
Dae Gon Lim, Ki Hyun Kim, Eunah Kang, Sun Hee Lim, Jeremy Ricci, Si Kwon Sung, Myoung Taek Kwon & Seong Hoon Jeong
Pages: 2381-2395
Published online: 26 May 2016
AbstractforComprehensive evaluation of carboxylated nanodiamond as a topical drug delivery system | Full Text | References | PDF (3.8 MB)
  • 163 Views
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Review

Review Article
Pericyte-targeting drug delivery and tissue engineering
Eunah Kang & Jong Wook Shin
Pages: 2397-2406
Published online: 27 May 2016
AbstractforPericyte-targeting drug delivery and tissue engineering | Full Text | References | PDF (1.4 MB)
  • 76 Views
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Original Research

Article
Schisandrae fructus enhances myogenic differentiation and inhibits atrophy through protein synthesis in human myotubes
Cy Hyun Kim, Jin-Hong Shin, Sung Jun Hwang, Yung Hyun Choi, Dae-Seong Kim & Cheol Min Kim
Pages: 2407-2415
Published online: 31 May 2016
AbstractforSchisandrae fructus enhances myogenic differentiation and inhibits atrophy through protein synthesis in human myotubes | Full Text | References | PDF (2.7 MB)
  • 81 Views
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Article
Chimeric HBcAg virus-like particles presenting a HPV 16 E7 epitope significantly suppressed tumor progression through preventive or therapeutic immunization in a TC-1-grafted mouse model
Xiaojie Chu, Yang Li, Qiong Long, Ye Xia, Yufeng Yao, Wenjia Sun, Weiwei Huang, Xu Yang, Cunbao Liu & Yanbing Ma
Pages: 2417-2429
Published online: 27 May 2016
AbstractforChimeric HBcAg virus-like particles presenting a HPV 16 E7 epitope significantly suppressed tumor progression through preventive or therapeutic immunization in a TC-1-grafted mouse model | Full Text | References | PDF (4.3 MB)
  • 101 Views
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Article
Bone regenerating effect of surface-functionalized titanium implants with sustained-release characteristics of strontium in ovariectomized rats
Vincent Offermanns, Ole Zoffmann Andersen, Gregor Riede, Inge Hald Andersen, Klaus Pagh Almtoft, Søren Sørensen, Michael Sillassen, Christian Sloth Jeppesen, Michael Rasse, Morten Foss & Frank Kloss
Pages: 2431-2442
Published online: 30 May 2016
AbstractforBone regenerating effect of surface-functionalized titanium implants with sustained-release characteristics of strontium in ovariectomized rats | Full Text | References | PDF (5.8 MB)
  • 75 Views
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Article
Efficacy of HIV antiviral polyanionic carbosilane dendrimer G2-S16 in the presence of semen
Rafael Ceña-Diez, Pilar García-Broncano, Francisco Javier de la Mata, Rafael Gómez & Mª Ángeles Muñoz-Fernández
Pages: 2443-2450
Published online: 30 May 2016
AbstractforEfficacy of HIV antiviral polyanionic carbosilane dendrimer G2-S16 in the presence of semen | Full Text | References | PDF (441.6 KB)
  • 58 Views
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Article
Annihilation of Leishmania by daylight responsive ZnO nanoparticles: a temporal relationship of reactive oxygen species-induced lipid and protein oxidation
Akhtar Nadhman, Malik Ihsanullah Khan, Samina Nazir, Momin Khan, Gul Shahnaz, Abida Raza, Dilawar Farhan Shams & Masoom Yasinzai
Pages: 2451-2461
Published online: 31 May 2016
AbstractforAnnihilation of Leishmania by daylight responsive ZnO nanoparticles: a temporal relationship of reactive oxygen species-induced lipid and protein oxidation | Full Text | References | PDF (3.3 MB)
  • 72 Views
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Article
Duality of β-glucan microparticles: antigen carrier and immunostimulants
Kim Baert, Bruno G De Geest, Henri De Greve, Eric Cox & Bert Devriendt
Pages: 2463-2469
Published online: 31 May 2016
AbstractforDuality of β-glucan microparticles: antigen carrier and immunostimulants | Full Text | References | PDF (734 KB)
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Article
The spherical nanoparticle-encapsulated chlorhexidine enhances anti-biofilm efficiency through an effective releasing mode and close microbial interactions
Xuan Li, Chi-Hin Wong, Tsz-Wing Ng, Cheng-Fei Zhang, Ken Cham-Fai Leung & Lijian Jin
Pages: 2471-2480
Published online: 31 May 2016
AbstractforThe spherical nanoparticle-encapsulated chlorhexidine enhances anti-biofilm efficiency through an effective releasing mode and close microbial interactions | Full Text | References | PDF (6.4 MB)
  • 91 Views
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Article
Magnetic resonance imaging of ultrasmall superparamagnetic iron oxide-labeled exosomes from stem cells: a new method to obtain labeled exosomes
Alice Busato, Roberta Bonafede, Pietro Bontempi, Ilaria Scambi, Lorenzo Schiaffino, Donatella Benati, Manuela Malatesta, Andrea Sbarbati, Pasquina Marzola & Raffaella Mariotti
Pages: 2481-2490
Published online: 01 Jun 2016
AbstractforMagnetic resonance imaging of ultrasmall superparamagnetic iron oxide-labeled exosomes from stem cells: a new method to obtain labeled exosomes | Full Text | References | PDF (2.7 MB)
  • 218 Views
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Review

Review Article
Recent insights into nanotechnology development for detection and treatment of colorectal cancer
Buddolla Viswanath, Sanghyo Kim & Kiyoung Lee
Pages: 2491-2504
Published online: 02 Jun 2016
AbstractforRecent insights into nanotechnology development for detection and treatment of colorectal cancer | Full Text | References | PDF (599.7 KB)
  • 255 Views
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Original Research

Article
Acute hematologic, hepatologic, and nephrologic changes after intraperitoneal injections of 18 nm gold nanoparticles in hamsters
Hazem Mohamed Saleh, Omar A Soliman, Mohamed Osama Elshazly, Alaa Raafat, Adel K Gohar & Taher A Salaheldin
Pages: 2505-2513
Published online: 03 Jun 2016
AbstractforAcute hematologic, hepatologic, and nephrologic changes after intraperitoneal injections of 18 nm gold nanoparticles in hamsters | Full Text | References | PDF (2.6 MB)
  • 58 Views
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Article
Preparation, characterization, and evaluation of antitumor effect of Brucea javanica oil cationic nanoemulsions
Ting-ting Liu, Li-Qiu Mu, Wei Dai, Chuan-bang Wang, Xin-Yi Liu & Da-Xiong Xiang
Pages: 2515-2529
Published online: 02 Jun 2016
AbstractforPreparation, characterization, and evaluation of antitumor effect of Brucea javanica oil cationic nanoemulsions | Full Text | References | PDF (7.5 MB)
  • 92 Views
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Article
Disinfection effects of undoped and silver-doped ceria powders of nanometer crystallite size
Dah-Shyang Tsai, Tzu-Sen Yang, Yu-Sheng Huang, Pei-Wen Peng & Keng-Liang Ou
Pages: 2531-2542
Published online: 02 Jun 2016
AbstractforDisinfection effects of undoped and silver-doped ceria powders of nanometer crystallite size | Full Text | References | PDF (8.3 MB)
  • 73 Views
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Article
Fast and safe fabrication of a free-standing chitosan/alginate nanomembrane to promote stem cell delivery and wound healing
Yi Kong, Rui Xu, Mohammad Ali Darabi, Wen Zhong, Gaoxing Luo, Malcolm MQ Xing & Jun Wu
Pages: 2543-2555
Published online: 03 Jun 2016
AbstractforFast and safe fabrication of a free-standing chitosan/alginate nanomembrane to promote stem cell delivery and wound healing | Full Text | References | PDF (5.1 MB)
  • 114 Views
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Article
Delivery of dexamethasone from bioactive nanofiber matrices stimulates odontogenesis of human dental pulp cells through integrin/BMP/mTOR signaling pathways
Hyun-Chang Lim, Ok Hyung Nam, Mi-joo Kim, Ahmed El-Fiqi, Hyung-Mun Yun, Yoo-Mi Lee, Guang-Zhen Jin, Hae-Hyoung Lee, Hae-Won Kim & Eun-Cheol Kim
Pages: 2557-2567
Published online: 03 Jun 2016
AbstractforDelivery of dexamethasone from bioactive nanofiber matrices stimulates odontogenesis of human dental pulp cells through integrin/BMP/mTOR signaling pathways | Full Text | References | PDF (2.2 MB)
  • 117 Views
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Article
Graphene oxide/multi-walled carbon nanotubes as nanofeatured scaffolds for the assisted deposition of nanohydroxyapatite: characterization and biological evaluation
Bruno VM Rodrigues, Nelly CS Leite, Bruno das Neves Cavalcanti, Newton S da Silva, Fernanda R Marciano, Evaldo J Corat, Thomas J Webster & Anderson O Lobo
Pages: 2569-2585
Published online: 13 Jun 2016
AbstractforGraphene oxide/multi-walled carbon nanotubes as nanofeatured scaffolds for the assisted deposition of nanohydroxyapatite: characterization and biological evaluation | Full Text | References | PDF (6.6 MB)
  • 99 Views
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Article
Intratracheal instillation of ethyl pyruvate nanoparticles prevents the development of shunt-flow-induced pulmonary arterial hypertension in a rat model
Kai Liu, Xiquan Zhang, Guangqing Cao, Yongjun Liu, Chuanzhen Liu, Hourong Sun & Xinyan Pang
Pages: 2587-2599
Published online: 03 Jun 2016
AbstractforIntratracheal instillation of ethyl pyruvate nanoparticles prevents the development of shunt-flow-induced pulmonary arterial hypertension in a rat model | Full Text | References | PDF (4.5 MB)
  • 46 Views
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Article
Design and statistical modeling of mannose-decorated dapsone-containing nanoparticles as a strategy of targeting intestinal M-cells
Alexandre CC Vieira, Luíse L Chaves, Marina Pinheiro, Domingos Ferreira, Bruno Sarmento & Salette Reis
Pages: 2601-2617
Published online: 03 Jun 2016
AbstractforDesign and statistical modeling of mannose-decorated dapsone-containing nanoparticles as a strategy of targeting intestinal M-cells | Full Text | References | PDF (4.6 MB)
  • 117 Views
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Article
Magnetic micro/nanoparticle flocculation-based signal amplification for biosensing
Omary Mzava, Zehra Taş & Kutay İçöz
Pages: 2619-2631
Published online: 28 Feb 2023
AbstractforMagnetic micro/nanoparticle flocculation-based signal amplification for biosensing | Full Text | References | PDF (2.1 MB)
  • 64 Views
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Article
Peptide-coated gold nanoparticles for modulation of angiogenesis in vivo
Catarina Roma-Rodrigues, Amelie Heuer-Jungemann, Alexandra R Fernandes, Antonios G Kanaras & Pedro V Baptista
Pages: 2633-2639
Published online: 07 Jun 2016
AbstractforPeptide-coated gold nanoparticles for modulation of angiogenesis in vivo | Full Text | References | PDF (1.4 MB)
  • 146 Views
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Article
Development, characterization, and in vivo assessment of mucoadhesive nanoparticles containing fluconazole for the local treatment of oral candidiasis
Seda Rençber, Sinem Yaprak Karavana, Fethiye Ferda Yılmaz, Bayri Eraç, Merve Nenni, Seda Özbal, Çetin Pekçetin, Hande Gurer-Orhan, Mine Hoşgör-Limoncu, Pelin Güneri & Gökhan Ertan
Pages: 2641-2653
Published online: 10 Jun 2016
AbstractforDevelopment, characterization, and in vivo assessment of mucoadhesive nanoparticles containing fluconazole for the local treatment of oral candidiasis | Full Text | References | PDF (3.2 MB)
  • 396 Views
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Article
XanoMatrix surfaces as scaffolds for mesenchymal stem cell culture and growth
Garima Bhardwaj & Thomas J Webster
Pages: 2655-2661
Published online: 07 Jun 2016
AbstractforXanoMatrix surfaces as scaffolds for mesenchymal stem cell culture and growth | Full Text | References | PDF (2.2 MB)
  • 50 Views
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Article
Fabrication of novel vesicles of triptolide for antirheumatoid activity with reduced toxicity in vitro and in vivo
Li Zhang, Tengteng Wang, Qiang Li, Jing Huang, Hao Xu, Jinlong Li, Yongjun Wang & Qianqian Liang
Pages: 2663-2673
Published online: 08 Jun 2016
AbstractforFabrication of novel vesicles of triptolide for antirheumatoid activity with reduced toxicity in vitro and in vivo | Full Text | References | PDF (4.4 MB)
  • 74 Views
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Article
In vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles
Cátia DF Lopes, Hugo Oliveira, Inês Estevão, Liliana Raquel Pires & Ana Paula Pêgo
Pages: 2675-2683
Published online: 28 Feb 2023
AbstractforIn vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles | Full Text | References | PDF (3.6 MB)
  • 78 Views
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Article
Elimination of the biphasic pharmacodynamics of 15d-PGJ2 by controlling its release from a nanoemulsion
Saed Abbasi, Kazuaki Kajimoto & Hideyoshi Harashima
Pages: 2685-2694
Published online: 08 Jun 2016
AbstractforElimination of the biphasic pharmacodynamics of 15d-PGJ2 by controlling its release from a nanoemulsion | Full Text | References | PDF (1.4 MB)
  • 52 Views
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Review

Review Article
From micro- to nanostructured implantable device for local anesthetic delivery
Laura Zorzetto, Paola Brambilla, Elena Marcello, Nora Bloise, Manuela De Gregori, Lorenzo Cobianchi, Andrea Peloso, Massimo Allegri, Livia Visai & Paola Petrini
Pages: 2695-2709
Published online: 08 Jun 2016
AbstractforFrom micro- to nanostructured implantable device for local anesthetic delivery | Full Text | References | PDF (1.8 MB)
  • 107 Views
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Original Research

Article
Evaluation of oxidative response and tissular damage in rat lungs exposed to silica-coated gold nanoparticles under static magnetic fields
Soumaya Ferchichi, Hamdi Trabelsi, Inès Azzouz, Amel Hanini, Ahmed Rejeb, Olfa Tebourbi, Mohsen Sakly & Hafedh Abdelmelek
Pages: 2711-2719
Published online: 08 Jun 2016
AbstractforEvaluation of oxidative response and tissular damage in rat lungs exposed to silica-coated gold nanoparticles under static magnetic fields | Full Text | References | PDF (3.9 MB)
  • 58 Views
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Article
Biodegradable micelles enhance the antiglioma activity of curcumin in vitro and in vivo
Songping Zheng, Xiang Gao, Xiaoxiao Liu, Ting Yu, Tianying Zheng, Yi Wang & Chao You
Pages: 2721-2736
Published online: 09 Jun 2016
AbstractforBiodegradable micelles enhance the antiglioma activity of curcumin in vitro and in vivo | Full Text | References | PDF (6 MB)
  • 68 Views
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Article
Impairments of spatial learning and memory following intrahippocampal injection in rats of 3-mercaptopropionic acid-modified CdTe quantum dots and molecular mechanisms
Tianshu Wu, Keyu He, Shengjun Ang, Jiali Ying, Shihan Zhang, Ting Zhang, Yuying Xue & Meng Tang
Pages: 2737-2755
Published online: 10 Jun 2016
AbstractforImpairments of spatial learning and memory following intrahippocampal injection in rats of 3-mercaptopropionic acid-modified CdTe quantum dots and molecular mechanisms | Full Text | References | PDF (5.2 MB)
  • 73 Views
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Article
Symbiosis theory-directed green synthesis of silver nanoparticles and their application in infected wound healing
Lu Wen, Pei Zeng, Liping Zhang, Wenli Huang, Hui Wang & Gang Chen
Pages: 2757-2767
Published online: 10 Jun 2016
AbstractforSymbiosis theory-directed green synthesis of silver nanoparticles and their application in infected wound healing | Full Text | References | PDF (2.5 MB)
  • 185 Views
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Article
Biocompatible nanocarriers that respond to oxidative environments via interactions between chitosan and multiple metal ions
Shichang Zhang, Liye Xia, Chenchen Ding, Lu Wen, Weihua Wan & Gang Chen
Pages: 2769-2784
Published online: 13 Jun 2016
AbstractforBiocompatible nanocarriers that respond to oxidative environments via interactions between chitosan and multiple metal ions | Full Text | References | PDF (6.8 MB)
  • 49 Views
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Article
Amphiphilic core–shell nanoparticles containing dense polyethyleneimine shells for efficient delivery of microRNA to Kupffer cells
Zuojin Liu, Dechao Niu, Junyong Zhang, Wenfeng Zhang, Yuan Yao, Pei Li & Jianping Gong
Pages: 2785-2797
Published online: 28 Feb 2023
AbstractforAmphiphilic core–shell nanoparticles containing dense polyethyleneimine shells for efficient delivery of microRNA to Kupffer cells | Full Text | References | PDF (4.5 MB)
  • 69 Views
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Article
Receptor-targeted, drug-loaded, functionalized graphene oxides for chemotherapy and photothermal therapy
Raj Kumar Thapa, Ju Yeon Choi, Bijay Kumar Poudel, Han-Gon Choi, Chul Soon Yong & Jong Oh Kim
Pages: 2799-2813
Published online: 13 Jun 2016
AbstractforReceptor-targeted, drug-loaded, functionalized graphene oxides for chemotherapy and photothermal therapy | Full Text | References | PDF (3 MB)
  • 64 Views
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Article
Phytosome-hyaluronic acid systems for ocular delivery of L-carnosine
Hamdy Abdelkader, Michael R Longman, Raid G Alany & Barbara Pierscionek
Pages: 2815-2827
Published online: 28 Feb 2023
AbstractforPhytosome-hyaluronic acid systems for ocular delivery of L-carnosine | Full Text | References | PDF (2.5 MB)
  • 159 Views
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Article
Development of self-nanoemulsifying drug delivery systems for the enhancement of solubility and oral bioavailability of fenofibrate, a poorly water-soluble drug
Kazi Mohsin, Rayan Alamri, Ajaz Ahmad, Mohammad Raish, Fars K Alanazi & Muhammad Delwar Hussain
Pages: 2829-2838
Published online: 14 Jun 2016
AbstractforDevelopment of self-nanoemulsifying drug delivery systems for the enhancement of solubility and oral bioavailability of fenofibrate, a poorly water-soluble drug | Full Text | References | PDF (636.4 KB)
  • 244 Views
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Article
Reinjury risk of nano-calcium oxalate monohydrate and calcium oxalate dihydrate crystals on injured renal epithelial cells: aggravation of crystal adhesion and aggregation
Qiong-Zhi Gan, Xin-Yuan Sun, Poonam Bhadja, Xiu-Qiong Yao & Jian-Ming Ouyang
Pages: 2839-2854
Published online: 28 Feb 2023
AbstractforReinjury risk of nano-calcium oxalate monohydrate and calcium oxalate dihydrate crystals on injured renal epithelial cells: aggravation of crystal adhesion and aggregation | Full Text | References | PDF (7.6 MB)
  • 106 Views
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Article
Transformation of eutectic emulsion to nanosuspension fabricating with solvent evaporation and ultrasonication technique
Thawatchai Phaechamud & Sarun Tuntarawongsa
Pages: 2855-2865
Published online: 14 Jun 2016
AbstractforTransformation of eutectic emulsion to nanosuspension fabricating with solvent evaporation and ultrasonication technique | Full Text | References | PDF (3.2 MB)
  • 101 Views
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Perspectives

Article
A brief perspective on the diverging theories of lymphatic targeting with colloids
Karthik Siram, Gregory Marslin, Chellan Vijaya Raghavan, Krishnamoorthy Balakumar, Habibur Rahman & Gregory Franklin
Pages: 2867-2872
Published online: 15 Jun 2016
AbstractforA brief perspective on the diverging theories of lymphatic targeting with colloids | Full Text | References | PDF (916 KB)
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Original Research

Article
Controlled release of curcumin from curcumin-loaded nanomicelles to prevent peritendinous adhesion during Achilles tendon healing in rats
Weizhong Zhang, Xuanyi Li, Mauro Comes Franchini, Ke Xu, Erica Locatelli, Robert C Martin, Ilaria Monaco, Yan Li & Shusen Cui
Pages: 2873-2881
Published online: 28 Feb 2023
AbstractforControlled release of curcumin from curcumin-loaded nanomicelles to prevent peritendinous adhesion during Achilles tendon healing in rats | Full Text | References | PDF (1.8 MB)
  • 114 Views
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Article
Comparative toxicity and biodistribution of copper nanoparticles and cupric ions in rats
In-Chul Lee, Je-Won Ko, Sung-Hyeuk Park, Je-Oh Lim, In-Sik Shin, Changjong Moon, Sung-Hwan Kim, Jeong-Doo Heo & Jong-Choon Kim
Pages: 2883-2900
Published online: 16 Jun 2016
AbstractforComparative toxicity and biodistribution of copper nanoparticles and cupric ions in rats | Full Text | References | PDF (3.2 MB)
  • 240 Views
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Article
Development of transmucosal patch loaded with anesthetic and analgesic for dental procedures and in vivo evaluation
Malviya Nidhi, M Nagaraju Patro, Somisetty Kusumvalli & Vemula Kusumdevi
Pages: 2901-2920
Published online: 20 Jun 2016
AbstractforDevelopment of transmucosal patch loaded with anesthetic and analgesic for dental procedures and in vivo evaluation | Full Text | References | PDF (5.8 MB)
  • 135 Views
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Article
Cyclosporine Amicellar delivery system for dry eyes
Han Kang, Kwang-Ho Cha, Wonkyung Cho, Junsung Park, Hee Jun Park, Bo Kyung Sun, Sang-Min Hyun & Sung-Joo Hwang
Pages: 2921-2933
Published online: 21 Jun 2016
AbstractforCyclosporine Amicellar delivery system for dry eyes | Full Text | References | PDF (1.3 MB)
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Review Article
A comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements
Christina Giannakou, Margriet VDZ Park, Wim H de Jong, Henk van Loveren, Rob J Vandebriel & Robert E Geertsma
Pages: 2935-2952
Published online: 22 Jun 2016
AbstractforA comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements | Full Text | References | PDF (3.7 MB)
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Article
Robust aptamer–polydopamine-functionalized M-PLGA–TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy
Guojun Xu, Xinghua Yu, Jinxie Zhang, Yingchao Sheng, Gan Liu, Wei Tao & Lin Mei
Pages: 2953-2965
Published online: 22 Jun 2016
AbstractforRobust aptamer–polydopamine-functionalized M-PLGA–TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy | Full Text | References | PDF (3.8 MB)
  • 144 Views
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Article
Chemically cross-linked silk fibroin hydrogel with enhanced elastic properties, biodegradability, and biocompatibility
Min Hee Kim & Won Ho Park
Pages: 2967-2978
Published online: 23 Jun 2016
AbstractforChemically cross-linked silk fibroin hydrogel with enhanced elastic properties, biodegradability, and biocompatibility | Full Text | References | PDF (5.4 MB)
  • 295 Views
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Article
A stabilizer-free and organic solvent-free method to prepare 10-hydroxycamptothecin nanocrystals: in vitro and in vivo evaluation
Xiaofeng Yang, Yingying Liu, Yanna Zhao, Meihua Han, Yifei Guo, Haixue Kuang & Xiangtao Wang
Pages: 2979-2994
Published online: 23 Jun 2016
AbstractforA stabilizer-free and organic solvent-free method to prepare 10-hydroxycamptothecin nanocrystals: in vitro and in vivo evaluation | Full Text | References | PDF (7.3 MB)
  • 65 Views
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Article
Increased cutaneous wound healing effect of biodegradable liposomes containing madecassoside: preparation optimization, in vitro dermal permeation, and in vivo bioevaluation
Zehao Li, Meifeng Liu, Huijuan Wang & Song Du
Pages: 2995-3007
Published online: 30 Jun 2016
AbstractforIncreased cutaneous wound healing effect of biodegradable liposomes containing madecassoside: preparation optimization, in vitro dermal permeation, and in vivo bioevaluation | Full Text | References | PDF (3.4 MB)
  • 190 Views
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Article
Metabolic fate of poly-(lactic-co-glycolic acid)-based curcumin nanoparticles following oral administration
Takahiro Harigae, Kiyotaka Nakagawa, Taiki Miyazawa, Nao Inoue, Fumiko Kimura, Ikuo Ikeda & Teruo Miyazawa
Pages: 3009-3022
Published online: 28 Jun 2016
AbstractforMetabolic fate of poly-(lactic-co-glycolic acid)-based curcumin nanoparticles following oral administration | Full Text | References | PDF (1.7 MB)
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Article
Cerium oxide nanoparticles inhibit the migration and proliferation of gastric cancer by increasing DHX15 expression
Yu-Feng Xiao, Jian-Mei Li, Su-Min Wang, Xin Yong, Bo Tang, Meng-Meng Jie, Hui Dong, Xiao-Chao Yang & Shi-Ming Yang
Pages: 3023-3034
Published online: 28 Feb 2023
AbstractforCerium oxide nanoparticles inhibit the migration and proliferation of gastric cancer by increasing DHX15 expression | Full Text | References | PDF (9 MB)
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Article
Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats
Mireia Campos-Martorell, Mary Cano-Sarabia, Alba Simats, Mar Hernández-Guillamon, Anna Rosell, Daniel Maspoch & Joan Montaner
Pages: 3035-3048
Published online: 29 Jun 2016
AbstractforCharge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats | Full Text | References | PDF (2.2 MB)
  • 109 Views
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Article
Effects of the protein corona on liposome–liposome and liposome–cell interactions
Claudia Corbo, Roberto Molinaro, Francesca Taraballi, Naama E Toledano Furman, Michael B Sherman, Alessandro Parodi, Francesco Salvatore & Ennio Tasciotti
Pages: 3049-3063
Published online: 04 Jul 2016
AbstractforEffects of the protein corona on liposome–liposome and liposome–cell interactions | Full Text | References | PDF (4.6 MB)
  • 226 Views
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Article
Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells
Yinghua Li, Zhengfang Lin, Mingqi Zhao, Tiantian Xu, Changbing Wang, Huimin Xia, Hanzhong Wang & Bing Zhu
Pages: 3065-3076
Published online: 05 Jul 2016
AbstractforMultifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells | Full Text | References | PDF (3.1 MB)
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Review Article
Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside
Timofei S Zatsepin, Yuri V Kotelevtsev & Victor Koteliansky
Pages: 3077-3086
Published online: 05 Jul 2016
AbstractforLipid nanoparticles for targeted siRNA delivery – going from bench to bedside | Full Text | References | PDF (591.8 KB)
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Article
Functionalized milk-protein-coated magnetic nanoparticles for MRI-monitored targeted therapy of pancreatic cancer
Jing Huang, Weiping Qian, Liya Wang, Hui Wu, Hongyu Zhou, Andrew Yongqiang Wang, Hongbo Chen, Lily Yang & Hui Mao
Pages: 3087-3099
Published online: 07 Jul 2016
AbstractforFunctionalized milk-protein-coated magnetic nanoparticles for MRI-monitored targeted therapy of pancreatic cancer | Full Text | References | PDF (7.9 MB)
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Article
Therapeutic effect of apatinib-loaded nanoparticles on diabetes-induced retinal vascular leakage
Ji Hoon Jeong, Hong Khanh Nguyen, Jung Eun Lee & Wonhee Suh
Pages: 3101-3109
Published online: 07 Jul 2016
AbstractforTherapeutic effect of apatinib-loaded nanoparticles on diabetes-induced retinal vascular leakage | Full Text | References | PDF (2.9 MB)
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Article
Effect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo
Yuling Luo, Zhongbing Liu, Xiaoqin Zhang, Juan Huang, Xin Yu, Jinwei Li, Dan Xiong, Xiaoduan Sun & Zhirong Zhong
Pages: 3111-3129
Published online: 12 Jul 2016
AbstractforEffect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo | Full Text | References | PDF (8.6 MB)
  • 149 Views
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Article
Green synthesis of multifunctional silver and gold nanoparticles from the oriental herbal adaptogen: Siberian ginseng
Ragavendran Abbai, Ramya Mathiyalagan, Josua Markus, Yeon-Ju Kim, Chao Wang, Priyanka Singh, Sungeun Ahn, Mohamed El-Agamy Farh & Deok Chun Yang
Pages: 3131-3143
Published online: 11 Jul 2016
AbstractforGreen synthesis of multifunctional silver and gold nanoparticles from the oriental herbal adaptogen: Siberian ginseng | Full Text | References | PDF (2.7 MB)
  • 188 Views
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Article
Controlled release of recombinant human cementum protein 1 from electrospun multiphasic scaffold for cementum regeneration
Xiaofeng Chen, Yu Liu, Leiying Miao, Yangyang Wang, Shuangshuang Ren, Xuebin Yang, Yong Hu & Weibin Sun
Pages: 3145-3158
Published online: 12 Jul 2016
AbstractforControlled release of recombinant human cementum protein 1 from electrospun multiphasic scaffold for cementum regeneration | Full Text | References | PDF (5.2 MB)
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Article
“Smart” nickel oxide based core–shell nanoparticles for combined chemo and photodynamic cancer therapy
Shazia Bano, Samina Nazir, Saeeda Munir, Mohamed Fahad AlAjmi, Muhammad Afzal & Kehkashan Mazhar
Pages: 3159-3166
Published online: 12 Jul 2016
Abstractfor“Smart” nickel oxide based core–shell nanoparticles for combined chemo and photodynamic cancer therapy | Full Text | References | PDF (1.2 MB)
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Article
Vitamin E succinate-conjugated F68 micelles for mitoxantrone delivery in enhancing anticancer activity
Yuling Liu, Yingqi Xu, Minghui Wu, Lijiao Fan, Chengwei He, Jian-Bo Wan, Peng Li, Meiwan Chen & Hui Li
Pages: 3167-3178
Published online: 12 Jul 2016
AbstractforVitamin E succinate-conjugated F68 micelles for mitoxantrone delivery in enhancing anticancer activity | Full Text | References | PDF (2.9 MB)
  • 85 Views
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Article
In vitro and in vivo biocompatibility and osteogenesis of graphene-reinforced nanohydroxyapatite polyamide66 ternary biocomposite as orthopedic implant material
Shiyang Zhang, Qiming Yang, Weikang Zhao, Bo Qiao, Hongwang Cui, Jianjun Fan, Hong Li, Xiaolin Tu & Dianming Jiang
Pages: 3179-3189
Published online: 13 Jul 2016
AbstractforIn vitro and in vivo biocompatibility and osteogenesis of graphene-reinforced nanohydroxyapatite polyamide66 ternary biocomposite as orthopedic implant material | Full Text | References | PDF (5 MB)
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Review Article
Remote magnetic targeting of iron oxide nanoparticles for cardiovascular diagnosis and therapeutic drug delivery: where are we now?
Michael Bietenbeck, Anca Florian, Cornelius Faber, Udo Sechtem & Ali Yilmaz
Pages: 3191-3203
Published online: 28 Feb 2023
AbstractforRemote magnetic targeting of iron oxide nanoparticles for cardiovascular diagnosis and therapeutic drug delivery: where are we now? | Full Text | References | PDF (2.8 MB)
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Article
Silencing tumor necrosis factor-alpha in vitro from small interfering RNA-decorated titanium nanotube array can facilitate osteogenic differentiation of mesenchymal stem cells
Zhenlin Wang, Zhiqiang Hu, Dawei Zhang, Mengchuan Zhuo, Jiwei Cheng, Xingping Xu, Yongming Xing & Jie Fan
Pages: 3205-3214
Published online: 14 Jul 2016
AbstractforSilencing tumor necrosis factor-alpha in vitro from small interfering RNA-decorated titanium nanotube array can facilitate osteogenic differentiation of mesenchymal stem cells | Full Text | References | PDF (3.8 MB)
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Article
Sol–gel dip coating of yttria-stabilized tetragonal zirconia dental ceramic by aluminosilicate nanocomposite as a novel technique to improve the bonding of veneering porcelain
Azamsadat Madani, Mohammadreza Nakhaei, Parisa Karami, Ghadir Rajabzadeh, Sahar Salehi & Hossein Bagheri
Pages: 3215-3223
Published online: 14 Jul 2016
AbstractforSol–gel dip coating of yttria-stabilized tetragonal zirconia dental ceramic by aluminosilicate nanocomposite as a novel technique to improve the bonding of veneering porcelain | Full Text | References | PDF (5.3 MB)
  • 96 Views
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Article
Synthesis, characterization, and efficacy of antituberculosis isoniazid zinc aluminum-layered double hydroxide based nanocomposites
Bullo Saifullah, Mohamed Ezzat El Zowalaty, Palanisamy Arulselvan, Sharida Fakurazi, Thomas J Webster, Benjamin Mahler Geilich & Mohd Zobir Hussein
Pages: 3225-3237
Published online: 28 Feb 2023
AbstractforSynthesis, characterization, and efficacy of antituberculosis isoniazid zinc aluminum-layered double hydroxide based nanocomposites | Full Text | References | PDF (1.6 MB)
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Article
Annonaceous acetogenins nanosuspensions stabilized by PCL-PEG block polymer: significantly improved antitumor efficacy
Jingyi Hong, Yanhong Li, Yijing Li, Yao Xiao, Haixue Kuang & Xiangtao Wang
Pages: 3239-3253
Published online: 28 Feb 2023
AbstractforAnnonaceous acetogenins nanosuspensions stabilized by PCL-PEG block polymer: significantly improved antitumor efficacy | Full Text | References | PDF (3.7 MB)
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Article
Controlled release hydrogen sulfide delivery system based on mesoporous silica nanoparticles protects graft endothelium from ischemia–reperfusion injury
Wenshuo Wang, Xiaotian Sun, Huili Zhang, Cheng Yang, Ye Liu, Wuli Yang, Changfa Guo & Chunsheng Wang
Pages: 3255-3263
Published online: 28 Feb 2023
AbstractforControlled release hydrogen sulfide delivery system based on mesoporous silica nanoparticles protects graft endothelium from ischemia–reperfusion injury | Full Text | References | PDF (4.8 MB)
  • 60 Views
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Article
Preclinical systemic toxicity evaluation of chitosan-solid lipid nanoparticle-encapsulated aspirin and curcumin in combination with free sulforaphane in BALB/c mice
Arvind Thakkar, Sushma Chenreddy, Astrid Thio, Wael Khamas, Jeffrey Wang & Sunil Prabhu
Pages: 3265-3276
Published online: 28 Feb 2023
AbstractforPreclinical systemic toxicity evaluation of chitosan-solid lipid nanoparticle-encapsulated aspirin and curcumin in combination with free sulforaphane in BALB/c mice | Full Text | References | PDF (2.7 MB)
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Article
Proretinal nanoparticles: stability, release, efficacy, and irritation
Pimolphan Pisetpackdeekul, Piyapan Supmuang, Porntip Pan-In, Wijit Banlunara, Benchaphorn Limcharoen, Chayada Kokpol & Supason Wanichwecharungruang
Pages: 3277-3286
Published online: 28 Feb 2023
AbstractforProretinal nanoparticles: stability, release, efficacy, and irritation | Full Text | References | PDF (2.5 MB)
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Review Article
Nanobody-derived nanobiotechnology tool kits for diverse biomedical and biotechnology applications
Yongzhong Wang, Zhen Fan, Lei Shao, Xiaowei Kong, Xianjuan Hou, Dongrui Tian, Ying Sun, Yazhong Xiao & Li Yu
Pages: 3287-3303
Published online: 21 Jul 2016
AbstractforNanobody-derived nanobiotechnology tool kits for diverse biomedical and biotechnology applications | Full Text | References | PDF (3.3 MB)
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Article
Endothelial glycocalyx conditions influence nanoparticle uptake for passive targeting
Ming J Cheng, Rajiv Kumar, Srinivas Sridhar, Thomas J Webster & Eno E Ebong
Pages: 3305-3315
Published online: 21 Jul 2016
AbstractforEndothelial glycocalyx conditions influence nanoparticle uptake for passive targeting | Full Text | References | PDF (2.1 MB)
  • 91 Views
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Article
Radiolabeling, whole-body single photon emission computed tomography/computed tomography imaging, and pharmacokinetics of carbon nanohorns in mice
Minfang Zhang, Dhifaf A Jasim, Cécilia Ménard-Moyon, Antonio Nunes, Sumio Iijima, Alberto Bianco, Masako Yudasaka & Kostas Kostarelos
Pages: 3317-3330
Published online: 22 Jul 2016
AbstractforRadiolabeling, whole-body single photon emission computed tomography/computed tomography imaging, and pharmacokinetics of carbon nanohorns in mice | Full Text | References | PDF (3.7 MB)
  • 54 Views
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Article
Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NLRP3 inflammasome activation in rats
Zhengwang Cao, Yiliang Fang, Yonghui Lu, Fenghua Qian, Qinglong Ma, Mingdi He, Huifeng Pi, Zhengping Yu & Zhou Zhou
Pages: 3331-3346
Published online: 22 Jul 2016
AbstractforExposure to nickel oxide nanoparticles induces pulmonary inflammation through NLRP3 inflammasome activation in rats | Full Text | References | PDF (5.1 MB)
  • 59 Views
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Article
Gallic acid conjugated with gold nanoparticles: antibacterial activity and mechanism of action on foodborne pathogens
Narintorn Rattanata, Sompong Klaynongsruang, Chanvit Leelayuwat, Temduang Limpaiboon, Aroonlug Lulitanond, Patcharee Boonsiri, Sirinart Chio-Srichan, Siriwat Soontaranon, Supagorn Rugmai & Jureerut Daduang
Pages: 3347-3356
Published online: 27 Jul 2016
AbstractforGallic acid conjugated with gold nanoparticles: antibacterial activity and mechanism of action on foodborne pathogens | Full Text | References | PDF (2.8 MB)
  • 187 Views
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Article
A novel temperature-responsive micelle for enhancing combination therapy
Cheng-Liang Peng, Yuan-I Chen, Hung-Jen Liu, Pei-Chi Lee, Tsai-Yueh Luo & Ming-Jium Shieh
Pages: 3357-3369
Published online: 25 Jul 2016
AbstractforA novel temperature-responsive micelle for enhancing combination therapy | Full Text | References | PDF (3.2 MB)
  • 66 Views
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Article
Inhibition of autophagy contributes to the toxicity of cadmium telluride quantum dots in Saccharomyces cerevisiae
Junpeng Fan, Ming Shao, Lu Lai, Yi Liu & Zhixiong Xie
Pages: 3371-3383
Published online: 25 Jul 2016
AbstractforInhibition of autophagy contributes to the toxicity of cadmium telluride quantum dots in Saccharomyces cerevisiae | Full Text | References | PDF (6.3 MB)
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Article
Augmenting regional and targeted delivery in the pulmonary acinus using magnetic particles
Yan Ostrovski, Philipp Hofemeier & Josué Sznitman
Pages: 3385-3395
Published online: 26 Jul 2016
AbstractforAugmenting regional and targeted delivery in the pulmonary acinus using magnetic particles | Full Text | References | PDF (2.5 MB)
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Article
Continuous synthesis of drug-loaded nanoparticles using microchannel emulsification and numerical modeling: effect of passive mixing
Isabel Ortiz de Solorzano, Laura Uson, Ane Larrea, Mario Miana, Victor Sebastian & Manuel Arruebo
Pages: 3397-3416
Published online: 25 Jul 2016
AbstractforContinuous synthesis of drug-loaded nanoparticles using microchannel emulsification and numerical modeling: effect of passive mixing | Full Text | References | PDF (14.9 MB)
  • 220 Views
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Article
Optimization, formulation, and characterization of multiflavonoids-loaded flavanosome by bulk or sequential technique
Govindarajan Karthivashan, Mas Jaffri Masarudin, Aminu Umar Kura, Faridah Abas & Sharida Fakurazi
Pages: 3417-3434
Published online: 27 Jul 2016
AbstractforOptimization, formulation, and characterization of multiflavonoids-loaded flavanosome by bulk or sequential technique | Full Text | References | PDF (5.5 MB)
  • 138 Views
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Article
Degradability, biocompatibility, and osteogenesis of biocomposite scaffolds containing nano magnesium phosphate and wheat protein both in vitro and in vivo for bone regeneration
Yan Xia, Panyu Zhou, Fei Wang, Chao Qiu, Panfeng Wang, Yuntong Zhang, Liming Zhao & Shuogui Xu
Pages: 3435-3449
Published online: 26 Jul 2016
AbstractforDegradability, biocompatibility, and osteogenesis of biocomposite scaffolds containing nano magnesium phosphate and wheat protein both in vitro and in vivo for bone regeneration | Full Text | References | PDF (10.3 MB)
  • 59 Views
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Article
Cabazitaxel-loaded human serum albumin nanoparticles as a therapeutic agent against prostate cancer
Na Qu, Robert J Lee, Yating Sun, Guangsheng Cai, Junyang Wang, Mengqiao Wang, Jiahui Lu, Qingfan Meng, Lirong Teng, Di Wang & Lesheng Teng
Pages: 3451-3459
Published online: 26 Jul 2016
AbstractforCabazitaxel-loaded human serum albumin nanoparticles as a therapeutic agent against prostate cancer | Full Text | References | PDF (2.9 MB)
  • 194 Views
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Article
Photothermal effects of laser-activated surface plasmonic gold nanoparticles on the apoptosis and osteogenesis of osteoblast-like cells
Lih-Rou Rau, Wan-Yu Huang, Jiunn-Woei Liaw & Shiao-Wen Tsai
Pages: 3461-3473
Published online: 27 Jul 2016
AbstractforPhotothermal effects of laser-activated surface plasmonic gold nanoparticles on the apoptosis and osteogenesis of osteoblast-like cells | Full Text | References | PDF (5.3 MB)
  • 87 Views
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Article
Effects of surface charges of gold nanoclusters on long-term in vivo biodistribution, toxicity, and cancer radiation therapy
Jun-Ying Wang, Jie Chen, Jiang Yang, Hao Wang, Xiu Shen, Yuan-Ming Sun, Meili Guo & Xiao-Dong Zhang
Pages: 3475-3485
Published online: 27 Jul 2016
AbstractforEffects of surface charges of gold nanoclusters on long-term in vivo biodistribution, toxicity, and cancer radiation therapy | Full Text | References | PDF (3.7 MB)
  • 119 Views
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Article
A nano-sandwich construct built with graphene nanosheets and carbon nanotubes enhances mechanical properties of hydroxyapatite–polyetheretherketone scaffolds
Pei Feng, Shuping Peng, Ping Wu, Chengde Gao, Wei Huang, Youwen Deng, Tao Xiao & Cijun Shuai
Pages: 3487-3500
Published online: 28 Jul 2016
AbstractforA nano-sandwich construct built with graphene nanosheets and carbon nanotubes enhances mechanical properties of hydroxyapatite–polyetheretherketone scaffolds | Full Text | References | PDF (5.5 MB)
  • 120 Views
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Article
Nanostructured lipid carriers loaded with resveratrol modulate human dendritic cells
João P Barbosa, Ana R Neves, Andreia M Silva, Mário A Barbosa, M Salette Reis & Susana G Santos
Pages: 3501-3516
Published online: 28 Jul 2016
AbstractforNanostructured lipid carriers loaded with resveratrol modulate human dendritic cells | Full Text | References | PDF (3.5 MB)
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Article
The synergistic radiosensitizing effect of tirapazamine-conjugated gold nanoparticles on human hepatoma HepG2 cells under X-ray irradiation
Xi Liu, Yan Liu, Pengcheng Zhang, Xiaodong Jin, Xiaogang Zheng, Fei Ye, Weiqiang Chen & Qiang Li
Pages: 3517-3531
Published online: 28 Feb 2023
AbstractforThe synergistic radiosensitizing effect of tirapazamine-conjugated gold nanoparticles on human hepatoma HepG2 cells under X-ray irradiation | Full Text | References | PDF (3.7 MB)
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Article
Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins
Maryna Perepelyuk, Christina Maher, Ashakumary Lakshmikuttyamma & Sunday A Shoyele
Pages: 3533-3544
Published online: 28 Jul 2016
AbstractforAptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins | Full Text | References | PDF (1.4 MB)
  • 106 Views
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Article
Degradability, cytocompatibility, and osteogenesis of porous scaffolds of nanobredigite and PCL–PEG–PCL composite
Jun Hou, Donghui Fan, Lingming Zhao, Baoqin Yu, Jiacan Su, Jie Wei & Jung-Woog Shin
Pages: 3545-3555
Published online: 28 Jul 2016
AbstractforDegradability, cytocompatibility, and osteogenesis of porous scaffolds of nanobredigite and PCL–PEG–PCL composite | Full Text | References | PDF (3.9 MB)
  • 79 Views
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Article
Size-dependent cytotoxicity of Fe3O4 nanoparticles induced by biphasic regulation of oxidative stress in different human hepatoma cells
Yuexia Xie, Dejun Liu, Chenlei Cai, Xiaojing Chen, Yan Zhou, Liangliang Wu, Yongwei Sun, Huili Dai, Xianming Kong & Peifeng Liu
Pages: 3557-3570
Published online: 28 Feb 2023
AbstractforSize-dependent cytotoxicity of Fe3O4 nanoparticles induced by biphasic regulation of oxidative stress in different human hepatoma cells | Full Text | References | PDF (6.2 MB)
  • 86 Views
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Article
Cubosome nanoparticles potentiate immune properties of immunostimulants
Zhenguang Liu, Li Luo, Sisi Zheng, Yale Niu, Ruonan Bo, Yee Huang, Jie Xing, Zhihua Li & Deyun Wang
Pages: 3571-3583
Published online: 29 Jul 2016
AbstractforCubosome nanoparticles potentiate immune properties of immunostimulants | Full Text | References | PDF (3.8 MB)
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Article
Inhibition of prostate cancer growth using doxorubicin assisted by ultrasound-targeted nanobubble destruction
Xiaozhou Fan, Luofu Wang, Yanli Guo, Xingyu Xiong, Lianhua Zhu & Kejing Fang
Pages: 3585-3596
Published online: 29 Jul 2016
AbstractforInhibition of prostate cancer growth using doxorubicin assisted by ultrasound-targeted nanobubble destruction | Full Text | References | PDF (6.8 MB)
  • 81 Views
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Article
Green synthesis and evaluation of silver nanoparticles as adjuvant in rabies veterinary vaccine
Vahid Asgary, Alireza Shoari, Fahimeh Baghbani-Arani, Seyed Ataollah Sadat Shandiz, Mohammad Sadeq Khosravy, Alireza Janani, Razieh Bigdeli, Rouzbeh Bashar & Reza Ahangari Cohan
Pages: 3597-3605
Published online: 28 Feb 2023
AbstractforGreen synthesis and evaluation of silver nanoparticles as adjuvant in rabies veterinary vaccine | Full Text | References | PDF (1.7 MB)
  • 476 Views
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Article
Bolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile
John P Hegarty, Jacek Krzeminski, Arun K Sharma, Diana Guzman-Villanueva, Volkmar Weissig & David B Stewart Sr
Pages: 3607-3619
Published online: 28 Feb 2023
AbstractforBolaamphiphile-based nanocomplex delivery of phosphorothioate gapmer antisense oligonucleotides as a treatment for Clostridium difficile | Full Text | References | PDF (1.4 MB)
  • 90 Views
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Article
Safety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approaches
Ana Raquel Madureira, Sara Nunes, Débora A Campos, João C Fernandes, Cláudia Marques, Monica Zuzarte, Beatriz Gullón, Luís M Rodríguez-Alcalá, Conceição Calhau, Bruno Sarmento, Ana Maria Gomes, Maria Manuela Pintado & Flávio Reis
Pages: 3621-3640
Published online: 28 Feb 2023
AbstractforSafety profile of solid lipid nanoparticles loaded with rosmarinic acid for oral use: in vitro and animal approaches | Full Text | References | PDF (2.7 MB)
  • 172 Views
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Article
The effect of red-allotrope selenium nanoparticles on head and neck squamous cell viability and growth
Christopher E Hassan & Thomas J Webster
Pages: 3641-3654
Published online: 01 Aug 2016
AbstractforThe effect of red-allotrope selenium nanoparticles on head and neck squamous cell viability and growth | Full Text | References | PDF (6.1 MB)
  • 75 Views
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Article
Combination of salinomycin and silver nanoparticles enhances apoptosis and autophagy in human ovarian cancer cells: an effective anticancer therapy
Xi-Feng Zhang & Sangiliyandi Gurunathan
Pages: 3655-3675
Published online: 02 Aug 2016
AbstractforCombination of salinomycin and silver nanoparticles enhances apoptosis and autophagy in human ovarian cancer cells: an effective anticancer therapy | Full Text | References | PDF (3.6 MB)
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Article
The cellular uptake mechanism, intracellular transportation, and exocytosis of polyamidoamine dendrimers in multidrug-resistant breast cancer cells
Jie Zhang, Dan Liu, Mengjun Zhang, Yuqi Sun, Xiaojun Zhang, Guannan Guan, Xiuli Zhao, Mingxi Qiao, Dawei Chen & Haiyang Hu
Pages: 3677-3690
Published online: 03 Aug 2016
AbstractforThe cellular uptake mechanism, intracellular transportation, and exocytosis of polyamidoamine dendrimers in multidrug-resistant breast cancer cells | Full Text | References | PDF (2.8 MB)
  • 128 Views
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Article
Rapid green synthesis of silver and gold nanoparticles using Dendropanax morbifera leaf extract and their anticancer activities
Chao Wang, Ramya Mathiyalagan, Yeon Ju Kim, Veronica Castro-Aceituno, Priyanka Singh, Sungeun Ahn, Dandan Wang & Deok Chun Yang
Pages: 3691-3701
Published online: 10 Aug 2016
AbstractforRapid green synthesis of silver and gold nanoparticles using Dendropanax morbifera leaf extract and their anticancer activities | Full Text | References | PDF (5.1 MB)
  • 325 Views
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Article
Development of nanostars as a biocompatible tumor contrast agent: toward in vivo SERS imaging
Antoine D’Hollander, Evelien Mathieu, Hilde Jans, Greetje Vande Velde, Tim Stakenborg, Pol Van Dorpe, Uwe Himmelreich & Liesbet Lagae
Pages: 3703-3714
Published online: 04 Aug 2016
AbstractforDevelopment of nanostars as a biocompatible tumor contrast agent: toward in vivo SERS imaging | Full Text | References | PDF (4.4 MB)
  • 124 Views
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Review

Review Article
Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?
Aline Raquel Voltan, Guillermo Quindós, Kaila P Medina Alarcón, Ana Marisa Fusco-Almeida, Maria José Soares Mendes-Giannini & Marlus Chorilli
Pages: 3715-3730
Published online: 08 Aug 2016
AbstractforFungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy? | Full Text | References | PDF (933.6 KB)
  • 258 Views
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Original Research

Article
Inhibition of E. coli and S. aureus with selenium nanoparticles synthesized by pulsed laser ablation in deionized water
G Guisbiers, Q Wang, E Khachatryan, LC Mimun, R Mendoza-Cruz, P Larese-Casanova, TJ Webster & KL Nash
Pages: 3731-3736
Published online: 08 Aug 2016
AbstractforInhibition of E. coli and S. aureus with selenium nanoparticles synthesized by pulsed laser ablation in deionized water | Full Text | References | PDF (1.1 MB)
  • 213 Views
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Article
Development of a bone-targeted pH-sensitive liposomal formulation containing doxorubicin: physicochemical characterization, cytotoxicity, and biodistribution evaluation in a mouse model of bone metastasis
Diêgo dos Santos Ferreira, Samilla Dornelas Faria, Sávia Caldeira de Araújo Lopes, Cláudia Salviano Teixeira, Angelo Malachias, Rogério Magalhães-Paniago, José Dias de Souza Filho, Bruno Luis de Jesus Pinto Oliveira, Alexander Ramos Guimarães, Peter Caravan, Lucas Antônio Miranda Ferreira, Ricardo José Alves & Mônica Cristina Oliveira
Pages: 3737-3751
Published online: 28 Feb 2023
AbstractforDevelopment of a bone-targeted pH-sensitive liposomal formulation containing doxorubicin: physicochemical characterization, cytotoxicity, and biodistribution evaluation in a mouse model of bone metastasis | Full Text | References | PDF (1 MB)
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Article
Polymer nanoparticles for cross-presentation of exogenous antigens and enhanced cytotoxic T-lymphocyte immune response
Chanyoung Song, Young-Woock Noh & Yong Taik Lim
Pages: 3753-3764
Published online: 05 Aug 2016
AbstractforPolymer nanoparticles for cross-presentation of exogenous antigens and enhanced cytotoxic T-lymphocyte immune response | Full Text | References | PDF (2.5 MB)
  • 84 Views
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Article
A dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-β1–42-injected mice
Tingting Jia, Zhiguo Sun, Ying Lu, Jie Gao, Hao Zou, Fangyuan Xie, Guoqing Zhang, Hao Xu, Duxin Sun, Yuan Yu & Yanqiang Zhong
Pages: 3765-3775
Published online: 05 Aug 2016
AbstractforA dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-β1–42-injected mice | Full Text | References | PDF (2.7 MB)
  • 123 Views
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Article
Improved oral bioavailability of poorly water-soluble glimepiride by utilizing microemulsion technique
Haiying Li, Tingting Pan, Ying Cui, Xiaxia Li, Jiefang Gao, Wenzhi Yang & Shigang Shen
Pages: 3777-3788
Published online: 05 Aug 2016
AbstractforImproved oral bioavailability of poorly water-soluble glimepiride by utilizing microemulsion technique | Full Text | References | PDF (2.6 MB)
  • 193 Views
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Article
Effects of silver nanoparticles in combination with antibiotics on the resistant bacteria Acinetobacter baumannii
Guoqing Wan, Lingao Ruan, Yu Yin, Tian Yang, Mei Ge & Xiaodong Cheng
Pages: 3789-3800
Published online: 28 Feb 2023
AbstractforEffects of silver nanoparticles in combination with antibiotics on the resistant bacteria Acinetobacter baumannii | Full Text | References | PDF (2.4 MB)
  • 420 Views
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Article
Using ferromagnetic nanoparticles with low Curie temperature for magnetic resonance imaging-guided thermoablation
Vít Herynek, Karolína Turnovcová, Pavel Veverka, Tereza Dědourková, Pavel Žvátora, Pavla Jendelová, Andrea Gálisová, Lucie Kosinová, Klára Jiráková & Eva Syková
Pages: 3801-3811
Published online: 08 Aug 2016
AbstractforUsing ferromagnetic nanoparticles with low Curie temperature for magnetic resonance imaging-guided thermoablation | Full Text | References | PDF (4.9 MB)
  • 73 Views
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Article
Improved skin permeation of methotrexate via nanosized ultradeformable liposomes
Alam Zeb, Omer Salman Qureshi, Hyung-Seo Kim, Ji-Hye Cha, Hoo-Seong Kim & Jin-Ki Kim
Pages: 3813-3824
Published online: 08 Aug 2016
AbstractforImproved skin permeation of methotrexate via nanosized ultradeformable liposomes | Full Text | References | PDF (2 MB)
  • 253 Views
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Article
Decreased Pseudomonas aeruginosa biofilm formation on nanomodified endotracheal tubes: a dynamic lung model
Mary C Machado & Thomas J Webster
Pages: 3825-3831
Published online: 09 Aug 2016
AbstractforDecreased Pseudomonas aeruginosa biofilm formation on nanomodified endotracheal tubes: a dynamic lung model | Full Text | References | PDF (1.7 MB)
  • 77 Views
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Article
Microwave-assisted green synthesis of superparamagnetic nanoparticles using fruit peel extracts: surface engineering, T2 relaxometry, and photodynamic treatment potential
Shazia Bano, Samina Nazir, Alia Nazir, Saeeda Munir, Tariq Mahmood, Muhammad Afzal, Farzana Latif Ansari & Kehkashan Mazhar
Pages: 3833-3848
Published online: 28 Feb 2023
AbstractforMicrowave-assisted green synthesis of superparamagnetic nanoparticles using fruit peel extracts: surface engineering, T2 relaxometry, and photodynamic treatment potential | Full Text | References | PDF (4.7 MB)
  • 157 Views
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Article
The intrinsic antimicrobial activity of citric acid-coated manganese ferrite nanoparticles is enhanced after conjugation with the antifungal peptide Cm-p5
Carlos Lopez-Abarrategui, Viviana Figueroa-Espi, Maria B Lugo-Alvarez, Caroline D Pereira, Hilda Garay, João ARG Barbosa, Rosana Falcão, Linnavel Jiménez-Hernández, Osvaldo Estévez-Hernández, Edilso Reguera, Octavio L Franco, Simoni C Dias & Anselmo J Otero-Gonzalez
Pages: 3849-3857
Published online: 28 Feb 2023
AbstractforThe intrinsic antimicrobial activity of citric acid-coated manganese ferrite nanoparticles is enhanced after conjugation with the antifungal peptide Cm-p5 | Full Text | References | PDF (1.2 MB)
  • 203 Views
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Article
Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes
Fei Gao, Ningjie Ma, Hong Zhou, Qing Wang, Hao Zhang, Pu Wang, Haoli Hou, Huan Wen & Lijia Li
Pages: 3859-3874
Published online: 28 Feb 2023
AbstractforZinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes | Full Text | References | PDF (3.6 MB)
  • 93 Views
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Article
Enhanced tumor delivery and antitumor response of doxorubicin-loaded albumin nanoparticles formulated based on a Schiff base
Fang Li, Chunli Zheng, Junbo Xin, Fangcheng Chen, Hua Ling, Linlin Sun, Thomas J Webster, Xin Ming & Jianping Liu
Pages: 3875-3890
Published online: 28 Feb 2023
AbstractforEnhanced tumor delivery and antitumor response of doxorubicin-loaded albumin nanoparticles formulated based on a Schiff base | Full Text | References | PDF (5.8 MB)
  • 137 Views
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Article
Aptamer-functionalized peptide H3CR5C as a novel nanovehicle for codelivery of fasudil and miRNA-195 targeting hepatocellular carcinoma
Ying Liu, Xin Wu, Yuan Gao, Jigang Zhang, Dandan Zhang, Shengying Gu, Guanhua Zhu, Gaolin Liu & Xiaoyu Li
Pages: 3891-3905
Published online: 28 Feb 2023
AbstractforAptamer-functionalized peptide H3CR5C as a novel nanovehicle for codelivery of fasudil and miRNA-195 targeting hepatocellular carcinoma | Full Text | References | PDF (3.6 MB)
  • 63 Views
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Article
Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress
Zih-Chan Lin, Chiang-Wen Lee, Ming-Horng Tsai, Horng-Huey Ko, Jia-You Fang, Yao-Chang Chiang, Chan-Jung Liang, Lee-Fen Hsu, Stephen Chu-Sung Hu & Feng-Lin Yen
Pages: 3907-3926
Published online: 28 Feb 2023
AbstractforEupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress | Full Text | References | PDF (4.7 MB)
  • 127 Views
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Article
Dual delivery of active antibactericidal agents and bone morphogenetic protein at sustainable high concentrations using biodegradable sheath-core-structured drug-eluting nanofibers
Yung-Hen Hsu, Chang-Tun Lin, Yi-Hsun Yu, Ying-Chao Chou, Shih-Jung Liu & Err-Cheng Chan
Pages: 3927-3937
Published online: 28 Feb 2023
AbstractforDual delivery of active antibactericidal agents and bone morphogenetic protein at sustainable high concentrations using biodegradable sheath-core-structured drug-eluting nanofibers | Full Text | References | PDF (2.9 MB)
  • 68 Views
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Article
Diagnosis of prostate cancer using anti-PSMA aptamer A10-3.2-oriented lipid nanobubbles
Xiaozhou Fan, Yanli Guo, Luofu Wang, Xingyu Xiong, Lianhua Zhu & Kejing Fang
Pages: 3939-3950
Published online: 28 Feb 2023
AbstractforDiagnosis of prostate cancer using anti-PSMA aptamer A10-3.2-oriented lipid nanobubbles | Full Text | References | PDF (3.2 MB)
  • 97 Views
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Article
Anti-EphA10 antibody-conjugated pH-sensitive liposomes for specific intracellular delivery of siRNA
Xinlong Zang, Huaiwei Ding, Xiufeng Zhao, Xiaowei Li, Zhouqi Du, Haiyang Hu, Mingxi Qiao, Dawei Chen, Yuihui Deng & Xiuli Zhao
Pages: 3951-3967
Published online: 28 Feb 2023
AbstractforAnti-EphA10 antibody-conjugated pH-sensitive liposomes for specific intracellular delivery of siRNA | Full Text | References | PDF (4 MB)
  • 91 Views
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Article
Synthesis, characterization, and performance evaluation of multilayered photoanodes by introducing mesoporous carbon and TiO2 for humic acid adsorption
Soraya Hosseini, Hossein Jahangirian, Thomas J Webster, Salman Masoudi Soltani & Mohamed Kheireddine Aroua
Pages: 3969-3978
Published online: 28 Feb 2023
AbstractforSynthesis, characterization, and performance evaluation of multilayered photoanodes by introducing mesoporous carbon and TiO2 for humic acid adsorption | Full Text | References | PDF (4.1 MB)
  • 49 Views
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Article
Styrene maleic acid-encapsulated paclitaxel micelles: antitumor activity and toxicity studies following oral administration in a murine orthotopic colon cancer model
Neha N Parayath, Hayley Nehoff, Samuel E Norton, Andrew J Highton, Sebastien Taurin, Roslyn A Kemp & Khaled Greish
Pages: 3979-3991
Published online: 28 Feb 2023
AbstractforStyrene maleic acid-encapsulated paclitaxel micelles: antitumor activity and toxicity studies following oral administration in a murine orthotopic colon cancer model | Full Text | References | PDF (3 MB)
  • 82 Views
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Article
EGF and curcumin co-encapsulated nanoparticle/hydrogel system as potent skin regeneration agent
Xiaoling Li, Xianlong Ye, Jianying Qi, Rangrang Fan, Xiang Gao, Yunzhou Wu, Liangxue Zhou, Aiping Tong & Gang Guo
Pages: 3993-4009
Published online: 28 Feb 2023
AbstractforEGF and curcumin co-encapsulated nanoparticle/hydrogel system as potent skin regeneration agent | Full Text | References | PDF (7.7 MB)
  • 205 Views
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Article
Guanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery
Jiankun Yu, Jinmin Zhang, Haonan Xing, Zhen Yang, Cuifang Cai, Conglu Zhang, Xiaoyun Zhao, Minjie Wei, Li Yang & Pingtian Ding
Pages: 4011-4024
Published online: 28 Feb 2023
AbstractforGuanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery | Full Text | References | PDF (6.2 MB)
  • 65 Views
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Article
Fusion between fluid liposomes and intact bacteria: study of driving parameters and in vitro bactericidal efficacy
Zhao Wang, Yufan Ma, Hayssam Khalil, Rutao Wang, Tingli Lu, Wen Zhao, Yang Zhang, Jamin Chen & Tao Chen
Pages: 4025-4036
Published online: 28 Feb 2023
AbstractforFusion between fluid liposomes and intact bacteria: study of driving parameters and in vitro bactericidal efficacy | Full Text | References | PDF (2.2 MB)
  • 140 Views
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Article
Combination of hydrotropic nicotinamide with nanoparticles for enhancing tacrolimus percutaneous delivery
Wenhui Pan, Mengyao Qin, Guoguang Zhang, Yueming Long, Wenyi Ruan, Jingtong Pan, Zushuai Wu, Tao Wan, Chuanbin Wu & Yuehong Xu
Pages: 4037-4050
Published online: 28 Feb 2023
AbstractforCombination of hydrotropic nicotinamide with nanoparticles for enhancing tacrolimus percutaneous delivery | Full Text | References | PDF (3.3 MB)
  • 83 Views
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Article
Targeting T1 and T2 dual modality enhanced magnetic resonance imaging of tumor vascular endothelial cells based on peptides-conjugated manganese ferrite nanomicelles
Mingfu Gong, Hua Yang, Song Zhang, Yan Yang, Dong Zhang, Zhaohui Li & Liguang Zou
Pages: 4051-4063
Published online: 28 Feb 2023
AbstractforTargeting T1 and T2 dual modality enhanced magnetic resonance imaging of tumor vascular endothelial cells based on peptides-conjugated manganese ferrite nanomicelles | Full Text | References | PDF (4.3 MB)
  • 58 Views
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Article
1,3-Bis(2-chloroethyl)-1-nitrosourea-loaded bovine serum albumin nanoparticles with dual magnetic resonance–fluorescence imaging for tracking of chemotherapeutic agents
Kuo-Chen Wei, Feng-Wei Lin, Chiung-Yin Huang, Chen-Chi M Ma, Ju-Yu Chen, Li-Ying Feng & Hung-Wei Yang
Pages: 4065-4075
Published online: 23 Aug 2016
Abstractfor1,3-Bis(2-chloroethyl)-1-nitrosourea-loaded bovine serum albumin nanoparticles with dual magnetic resonance–fluorescence imaging for tracking of chemotherapeutic agents | Full Text | References | PDF (2.2 MB)
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Article
Synergistic and complete reversal of the multidrug resistance of mitoxantrone hydrochloride by three-in-one multifunctional lipid-sodium glycocholate nanocarriers based on simultaneous BCRP and Bcl-2 inhibition
Guixia Ling, Tianhong Zhang, Peng Zhang, Jin Sun & Zhonggui He
Pages: 4077-4091
Published online: 23 Aug 2016
AbstractforSynergistic and complete reversal of the multidrug resistance of mitoxantrone hydrochloride by three-in-one multifunctional lipid-sodium glycocholate nanocarriers based on simultaneous BCRP and Bcl-2 inhibition | Full Text | References | PDF (1.7 MB)
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Article
Influence of freeze-drying and γ-irradiation in preclinical studies of flurbiprofen polymeric nanoparticles for ocular delivery using d-(+)-trehalose and polyethylene glycol
Gladys Rosario Ramos Yacasi, María Luisa García López, Marta Espina García, Alexander Parra Coca & Ana Cristina Calpena Campmany
Pages: 4093-4106
Published online: 28 Feb 2023
AbstractforInfluence of freeze-drying and γ-irradiation in preclinical studies of flurbiprofen polymeric nanoparticles for ocular delivery using d-(+)-trehalose and polyethylene glycol | Full Text | References | PDF (1.1 MB)
  • 82 Views
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Article
Nanomedicine engulfed by macrophages for targeted tumor therapy
Siwen Li, Song Feng, Li Ding, Yuxi Liu, Qiuyun Zhu, Zhiyu Qian & Yueqing Gu
Pages: 4107-4124
Published online: 28 Feb 2023
AbstractforNanomedicine engulfed by macrophages for targeted tumor therapy | Full Text | References | PDF (4.7 MB)
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Article
Cellular uptake mechanism and comparative evaluation of antineoplastic effects of paclitaxel–cholesterol lipid emulsion on triple-negative and non-triple-negative breast cancer cell lines
Jun Ye, Xuejun Xia, Wujun Dong, Huazhen Hao, Luhua Meng, Yanfang Yang, Renyun Wang, Yuanfeng Lyu & Yuling Liu
Pages: 4125-4140
Published online: 24 Aug 2016
AbstractforCellular uptake mechanism and comparative evaluation of antineoplastic effects of paclitaxel–cholesterol lipid emulsion on triple-negative and non-triple-negative breast cancer cell lines | Full Text | References | PDF (6.6 MB)
  • 82 Views
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Article
Multicomponent, peptide-targeted glycol chitosan nanoparticles containing ferrimagnetic iron oxide nanocubes for bladder cancer multimodal imaging
Jaehong Key, Deepika Dhawan, Christy L Cooper, Deborah W Knapp, Kwangmeyung Kim, Ick Chan Kwon, Kuiwon Choi, Kinam Park, Paolo Decuzzi & James F Leary
Pages: 4141-4155
Published online: 29 Aug 2016
AbstractforMulticomponent, peptide-targeted glycol chitosan nanoparticles containing ferrimagnetic iron oxide nanocubes for bladder cancer multimodal imaging | Full Text | References | PDF (3.2 MB)
  • 88 Views
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Article
The preosteoblast response of electrospinning PLGA/PCL nanofibers: effects of biomimetic architecture and collagen I
Yunzhu Qian, Hanbang Chen, Yang Xu, Jianxin Yang, Xuefeng Zhou, Feimin Zhang & Ning Gu
Pages: 4157-4171
Published online: 25 Aug 2016
AbstractforThe preosteoblast response of electrospinning PLGA/PCL nanofibers: effects of biomimetic architecture and collagen I | Full Text | References | PDF (5.8 MB)
  • 134 Views
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Article
Enhancement of tendon–bone healing via the combination of biodegradable collagen-loaded nanofibrous membranes and a three-dimensional printed bone-anchoring bolt
Ying-Chao Chou, Wen-Lin Yeh, Chien-Lin Chao, Yung-Heng Hsu, Yi-Hsun Yu, Jan-Kan Chen & Shih-Jung Liu
Pages: 4173-4186
Published online: 25 Aug 2016
AbstractforEnhancement of tendon–bone healing via the combination of biodegradable collagen-loaded nanofibrous membranes and a three-dimensional printed bone-anchoring bolt | Full Text | References | PDF (4.8 MB)
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Article
The influence of different long-circulating materials on the pharmacokinetics of liposomal vincristine sulfate
Jing Zhang, Yingchong Chen, Xiang Li, Xinli Liang & Xiaojian Luo
Pages: 4187-4197
Published online: 26 Aug 2016
AbstractforThe influence of different long-circulating materials on the pharmacokinetics of liposomal vincristine sulfate | Full Text | References | PDF (2.5 MB)
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Article
An integrated study on antimicrobial activity and ecotoxicity of quantum dots and quantum dots coated with the antimicrobial peptide indolicidin
Emilia Galdiero, Antonietta Siciliano, Valeria Maselli, Renato Gesuele, Marco Guida, Domenico Fulgione, Stefania Galdiero, Lucia Lombardi & Annarita Falanga
Pages: 4199-4211
Published online: 26 Aug 2016
AbstractforAn integrated study on antimicrobial activity and ecotoxicity of quantum dots and quantum dots coated with the antimicrobial peptide indolicidin | Full Text | References | PDF (1.2 MB)
  • 132 Views
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Article
In situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility
Fu-Yan Lv, Rui-Hua Dong, Zhao-Jian Li, Chong-Chong Qin, Xu Yan, Xiao-Xiao He, Yu Zhou, Shi-Ying Yan & Yun-Ze Long
Pages: 4213-4220
Published online: 29 Aug 2016
AbstractforIn situ precise electrospinning of medical glue fibers as nonsuture dural repair with high sealing capability and flexibility | Full Text | References | PDF (1.9 MB)
  • 75 Views
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Article
MDM2–MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance
Ilaria Moscetti, Emanuela Teveroni, Fabiola Moretti, Anna Rita Bizzarri & Salvatore Cannistraro
Pages: 4221-4229
Published online: 30 Aug 2016
AbstractforMDM2–MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance | Full Text | References | PDF (930 KB)
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Article
Preparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex
Seung Rim Hwang, Dong-Hyun Seo, Youngro Byun & Jin Woo Park
Pages: 4231-4246
Published online: 31 Aug 2016
AbstractforPreparation and in vivo evaluation of an orally available enteric-microencapsulated parathyroid hormone (1-34)-deoxycholic acid nanocomplex | Full Text | References | PDF (3.4 MB)
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Article
Arginine–glycine–aspartic acid–polyethylene glycol–polyamidoamine dendrimer conjugate improves liver-cell aggregation and function in 3-D spheroid culture
Zhanfei Chen, Fen Lian, Xiaoqian Wang, Yanling Chen & Nanhong Tang
Pages: 4247-4259
Published online: 31 Aug 2016
AbstractforArginine–glycine–aspartic acid–polyethylene glycol–polyamidoamine dendrimer conjugate improves liver-cell aggregation and function in 3-D spheroid culture | Full Text | References | PDF (3.2 MB)
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Article
In vivo assessment of bone marrow toxicity by gold nanoparticle-based bioconjugates in Crl:CD1(ICR) mice
Cristian Berce, Ciprian Lucan, Bobe Petrushev, Sanda Boca, Mirela Miclean, Orsolya Sarpataki, Simion Astilean, Anca Buzoianu, Ciprian Tomuleasa & Anca Bojan
Pages: 4261-4273
Published online: 01 Sep 2016
AbstractforIn vivo assessment of bone marrow toxicity by gold nanoparticle-based bioconjugates in Crl:CD1(ICR) mice | Full Text | References | PDF (9 MB)
  • 181 Views
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Article
The effect of ZnO nanoparticles on liver function in rats
Hua-Qiao Tang, Min Xu, Qian Rong, Ru-Wen Jin, Qi-Ji Liu & Ying-Lun Li
Pages: 4275-4285
Published online: 31 Aug 2016
AbstractforThe effect of ZnO nanoparticles on liver function in rats | Full Text | References | PDF (2.6 MB)
  • 247 Views
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Article
Development of TIMP1 magnetic nanoformulation for regulation of synaptic plasticity in HIV-1 infection
Venkata Subba Rao Atluri, Rahul Dev Jayant, Sudheesh Pilakka-Kanthikeel, Gabriella Garcia, Thangavel Samikkannu, Adriana Yndart, Ajeet Kaushik & Madhavan Nair
Pages: 4287-4298
Published online: 31 Aug 2016
AbstractforDevelopment of TIMP1 magnetic nanoformulation for regulation of synaptic plasticity in HIV-1 infection | Full Text | References | PDF (2.3 MB)
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Article
Systemic distribution of single-walled carbon nanotubes in a novel model: alteration of biochemical parameters, metabolic functions, liver accumulation, and inflammation in vivo
Elisa Principi, Rossana Girardello, Antonino Bruno, Isabella Manni, Elisabetta Gini, Arianna Pagani, Annalisa Grimaldi, Federico Ivaldi, Terenzio Congiu, Daniela De Stefano, Giulia Piaggio, Magda de Eguileor, Douglas M Noonan & Adriana Albini
Pages: 4299-4316
Published online: 01 Sep 2016
AbstractforSystemic distribution of single-walled carbon nanotubes in a novel model: alteration of biochemical parameters, metabolic functions, liver accumulation, and inflammation in vivo | Full Text | References | PDF (20.7 MB)
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Perspectives

Article
Advancements in nano-enabled therapeutics for neuroHIV management
Ajeet Kaushik, Rahul Dev Jayant & Madhavan Nair
Pages: 4317-4325
Published online: 01 Sep 2016
AbstractforAdvancements in nano-enabled therapeutics for neuroHIV management | Full Text | References | PDF (2.1 MB)
  • 70 Views
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Original Research

Article
Polyaniline-coated upconversion nanoparticles with upconverting luminescent and photothermal conversion properties for photothermal cancer therapy
Yadong Xing, Luoyuan Li, Xicheng Ai & Limin Fu
Pages: 4327-4338
Published online: 02 Sep 2016
AbstractforPolyaniline-coated upconversion nanoparticles with upconverting luminescent and photothermal conversion properties for photothermal cancer therapy | Full Text | References | PDF (3.8 MB)
  • 102 Views
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Article
Fabrication and hemocompatibility assessment of novel polyurethane-based bio-nanofibrous dressing loaded with honey and Carica papaya extract for the management of burn injuries
Arunpandian Balaji, Saravana Kumar Jaganathan, Ahmad Fauzi Ismail & Rathanasamy Rajasekar
Pages: 4339-4355
Published online: 02 Sep 2016
AbstractforFabrication and hemocompatibility assessment of novel polyurethane-based bio-nanofibrous dressing loaded with honey and Carica papaya extract for the management of burn injuries | Full Text | References | PDF (3.8 MB)
  • 180 Views
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Article
Defect density in multiwalled carbon nanotubes influences ovalbumin adsorption and promotes macrophage activation and CD4+ T-cell proliferation
Wei Bai, Achyut Raghavendra, Ramakrishna Podila & Jared M Brown
Pages: 4357-4371
Published online: 02 Sep 2016
AbstractforDefect density in multiwalled carbon nanotubes influences ovalbumin adsorption and promotes macrophage activation and CD4+ T-cell proliferation | Full Text | References | PDF (3.3 MB)
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Article
Self-assembled silk fibroin nanoparticles loaded with binary drugs in the treatment of breast carcinoma
Hui Li, Jian Tian, Anqing Wu, Jiamin Wang, Cuicui Ge & Ziling Sun
Pages: 4373-4380
Published online: 02 Sep 2016
AbstractforSelf-assembled silk fibroin nanoparticles loaded with binary drugs in the treatment of breast carcinoma | Full Text | References | PDF (2.7 MB)
  • 159 Views
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Article
Carbon nanotube-based substrates promote cardiogenesis in brown adipose-derived stem cells via β1-integrin-dependent TGF-β1 signaling pathway
Hongyu Sun, Yongchao Mou, Yi Li, Xia Li, Zi Chen, Kayla Duval, Zhu Huang, Ruiwu Dai, Lijun Tang & Fuzhou Tian
Pages: 4381-4395
Published online: 06 Sep 2016
AbstractforCarbon nanotube-based substrates promote cardiogenesis in brown adipose-derived stem cells via β1-integrin-dependent TGF-β1 signaling pathway | Full Text | References | PDF (4.1 MB)
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Article
Self-assembled nanoparticles based on amphiphilic chitosan derivative and arginine for oral curcumin delivery
Mazhar Ali Raja, Shah Zeenat, Muhammad Arif & Chenguang Liu
Pages: 4397-4412
Published online: 06 Sep 2016
AbstractforSelf-assembled nanoparticles based on amphiphilic chitosan derivative and arginine for oral curcumin delivery | Full Text | References | PDF (2.6 MB)
  • 141 Views
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Article
Inhibitory effect of magnetic Fe3O4 nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro
Meiyu Chen, Fei Xiong, Liang Ma, Hong Yao, Qinrong Wang, Lijun Wen, Qian Wang, Ning Gu & Suning Chen
Pages: 4413-4422
Published online: 06 Sep 2016
AbstractforInhibitory effect of magnetic Fe3O4 nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro | Full Text | References | PDF (2.8 MB)
  • 57 Views
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Article
Construction of magnetic-carbon-quantum-dots-probe-labeled apoferritin nanocages for bioimaging and targeted therapy
Hanchun Yao, Li Su, Man Zeng, Li Cao, Weiwei Zhao, Chengqun Chen, Bin Du & Jie Zhou
Pages: 4423-4438
Published online: 28 Feb 2023
AbstractforConstruction of magnetic-carbon-quantum-dots-probe-labeled apoferritin nanocages for bioimaging and targeted therapy | Full Text | References | PDF (4.1 MB)
  • 151 Views
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Article
Green synthesis of silver nanoparticles using Pimpinella anisum seeds: antimicrobial activity and cytotoxicity on human neonatal skin stromal cells and colon cancer cells
Mohamad S Alsalhi, Sandhanasamy Devanesan, Akram A Alfuraydi, Radhakrishnan Vishnubalaji, Murugan A Munusamy, Kadarkarai Murugan, Marcello Nicoletti & Giovanni Benelli
Pages: 4439-4449
Published online: 06 Sep 2016
AbstractforGreen synthesis of silver nanoparticles using Pimpinella anisum seeds: antimicrobial activity and cytotoxicity on human neonatal skin stromal cells and colon cancer cells | Full Text | References | PDF (4.8 MB)
  • 303 Views
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Article
3-Aminopropylsilane-modified iron oxide nanoparticles for contrast-enhanced magnetic resonance imaging of liver lesions induced by Opisthorchis felineus
Alexander M Demin, Alexandra G Pershina, Vladimir V Ivanov, Kseniya V Nevskaya, Oleg B Shevelev, Artyom S Minin, Iliya V Byzov, Alexey E Sazonov, Victor P Krasnov & Ludmila M Ogorodova
Pages: 4451-4463
Published online: 06 Sep 2016
Abstractfor3-Aminopropylsilane-modified iron oxide nanoparticles for contrast-enhanced magnetic resonance imaging of liver lesions induced by Opisthorchis felineus | Full Text | References | PDF (4 MB)
  • 64 Views
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Article
Development of paclitaxel-loaded liposomal nanocarrier stabilized by triglyceride incorporation
Soon-Seok Hong, Ju Yeon Choi, Jong Oh Kim, Mi-Kyung Lee, So Hee Kim & Soo-Jeong Lim
Pages: 4465-4477
Published online: 06 Sep 2016
AbstractforDevelopment of paclitaxel-loaded liposomal nanocarrier stabilized by triglyceride incorporation | Full Text | References | PDF (2 MB)
  • 128 Views
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Article
Pluronic® P123/F127 mixed micelles delivering sorafenib and its combination with verteporfin in cancer cells
Diogo Silva Pellosi, Francesca Moret, Aurore Fraix, Nino Marino, Sara Maiolino, Elisa Gaio, Noboru Hioka, Elena Reddi, Salvatore Sortino & Fabiana Quaglia
Pages: 4479-4494
Published online: 06 Sep 2016
AbstractforPluronic® P123/F127 mixed micelles delivering sorafenib and its combination with verteporfin in cancer cells | Full Text | References | PDF (1.8 MB)
  • 159 Views
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Article
Nanoemulsion as a carrier to improve the topical anti-inflammatory activity of stem bark extract of Rapanea ferruginea
Juarana Dal Mas, Tailyn Zermiani, Liliani C Thiesen, Joana LM Silveira, Kathryn ABS da Silva, Márcia M de Souza, Angela Malheiros, Tania MB Bresolin & Ruth M Lucinda-Silva
Pages: 4495-4507
Published online: 06 Sep 2016
AbstractforNanoemulsion as a carrier to improve the topical anti-inflammatory activity of stem bark extract of Rapanea ferruginea | Full Text | References | PDF (2.5 MB)
  • 159 Views
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Article
Epigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation
Nayana A Patil, WN Gade & Deepti D Deobagkar
Pages: 4509-4519
Published online: 07 Sep 2016
AbstractforEpigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation | Full Text | References | PDF (839.1 KB)
  • 153 Views
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Article
Experimental bladder regeneration using a poly-l-lactide/silk fibroin scaffold seeded with nanoparticle-labeled allogenic bone marrow stromal cells
Natalia M Yudintceva, Yulia A Nashchekina, Miralda I Blinova, Nadezhda V Orlova, Alexandr N Muraviov, Tatiana I Vinogradova, Magomed G Sheykhov, Elena Y Shapkova, Dmitriy V Emeljannikov, Petr K Yablonskii, Igor A Samusenko, Anastasiya L Mikhrina, Artem V Pakhomov & Maxim A Shevtsov
Pages: 4521-4533
Published online: 28 Feb 2023
AbstractforExperimental bladder regeneration using a poly-l-lactide/silk fibroin scaffold seeded with nanoparticle-labeled allogenic bone marrow stromal cells | Full Text | References | PDF (5.9 MB)
  • 77 Views
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Article
Efficient intravesical therapy of bladder cancer with cationic doxorubicin nanoassemblies
Xun Jin, Peilan Zhang, Li Luo, Hao Cheng, Yunzu Li, Ting Du, Bingwen Zou & Maling Gou
Pages: 4535-4544
Published online: 08 Sep 2016
AbstractforEfficient intravesical therapy of bladder cancer with cationic doxorubicin nanoassemblies | Full Text | References | PDF (2.9 MB)
  • 70 Views
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Article
Codelivery of thioridazine and doxorubicin using nanoparticles for effective breast cancer therapy
Xun Jin, Bingwen Zou, Li Luo, Chuanhong Zhong, Peilan Zhang, Hao Cheng, Yanfang Guo & Maling Gou
Pages: 4545-4552
Published online: 08 Sep 2016
AbstractforCodelivery of thioridazine and doxorubicin using nanoparticles for effective breast cancer therapy | Full Text | References | PDF (1.4 MB)
  • 80 Views
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Article
Design, characterization, and biological evaluation of curcumin-loaded surfactant-based systems for topical drug delivery
Bruno Fonseca-Santos, Aline Martins dos Santos, Camila Fernanda Rodero, Maria Palmira Daflon Gremião & Marlus Chorilli
Pages: 4553-4562
Published online: 28 Feb 2023
AbstractforDesign, characterization, and biological evaluation of curcumin-loaded surfactant-based systems for topical drug delivery | Full Text | References | PDF (779.9 KB)
  • 175 Views
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Article
d-α-Tocopheryl polyethylene glycol succinate/Solutol HS 15 mixed micelles for the delivery of baohuoside I against non-small-cell lung cancer: optimization and in vitro, in vivo evaluation
Hongmei Yan, Zhenhai Zhang, Xiaobin Jia & Jie Song
Pages: 4563-4571
Published online: 08 Sep 2016
Abstractford-α-Tocopheryl polyethylene glycol succinate/Solutol HS 15 mixed micelles for the delivery of baohuoside I against non-small-cell lung cancer: optimization and in vitro, in vivo evaluation | Full Text | References | PDF (1.2 MB)
  • 86 Views
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Article
Folate-conjugated boron nitride nanospheres for targeted delivery of anticancer drugs
Shini Feng, Huijie Zhang, Ting Yan, Dandi Huang, Chunyi Zhi, Hideki Nakanishi & Xiao-Dong Gao
Pages: 4573-4582
Published online: 28 Feb 2023
AbstractforFolate-conjugated boron nitride nanospheres for targeted delivery of anticancer drugs | Full Text | References | PDF (2.1 MB)
  • 93 Views
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Article
Synthesis of composite magnetic nanoparticles Fe3O4 with alendronate for osteoporosis treatment
Ming-Song Lee, Chao-Ming Su, Jih-Chao Yeh, Pei-Ru Wu, Tien-Yao Tsai & Shyh-Liang Lou
Pages: 4583-4594
Published online: 12 Sep 2016
AbstractforSynthesis of composite magnetic nanoparticles Fe3O4 with alendronate for osteoporosis treatment | Full Text | References | PDF (4 MB)
  • 119 Views
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Article
The effect of neutral-surface iron oxide nanoparticles on cellular uptake and signaling pathways
Eunjoo Kim, Joon Mee Kim, Lucia Kim, Suk Jin Choi, In Suh Park, Jee Young Han, Young Chae Chu, Eun Sook Choi, Kun Na & Soon-Sun Hong
Pages: 4595-4607
Published online: 13 Sep 2016
AbstractforThe effect of neutral-surface iron oxide nanoparticles on cellular uptake and signaling pathways | Full Text | References | PDF (3.5 MB)
  • 73 Views
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Article
Effective combination treatment of lung cancer cells by single vehicular delivery of siRNA and different anticancer drugs
Jinming Li, Yuanyuan Wang, Shanshan Xue, Jinghua Sun, Wei Zhang, Ping Hu, Liangnian Ji & Zongwan Mao
Pages: 4609-4624
Published online: 28 Feb 2023
AbstractforEffective combination treatment of lung cancer cells by single vehicular delivery of siRNA and different anticancer drugs | Full Text | References | PDF (3.5 MB)
  • 57 Views
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Article
Iron oxide nanoparticles modulate lipopolysaccharide-induced inflammatory responses in primary human monocytes
Susann Grosse, Jørgen Stenvik & Asbjørn M Nilsen
Pages: 4625-4642
Published online: 13 Sep 2016
AbstractforIron oxide nanoparticles modulate lipopolysaccharide-induced inflammatory responses in primary human monocytes | Full Text | References | PDF (8.8 MB)
  • 95 Views
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Article
Dual-function synthetic peptide derived from BMP4 for highly efficient tumor targeting and antiangiogenesis
Suk Hyun Choi, Jue Yeon Lee, Jin Sook Suh, Yoon Shin Park, Chong Pyoung Chung & Yoon Jeong Park
Pages: 4643-4656
Published online: 13 Sep 2016
AbstractforDual-function synthetic peptide derived from BMP4 for highly efficient tumor targeting and antiangiogenesis | Full Text | References | PDF (4.6 MB)
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Article
Metal oxide nanoparticles interact with immune cells and activate different cellular responses
Rosana Simón-Vázquez, Tamara Lozano-Fernández, Angela Dávila-Grana & Africa González-Fernández
Pages: 4657-4668
Published online: 14 Sep 2016
AbstractforMetal oxide nanoparticles interact with immune cells and activate different cellular responses | Full Text | References | PDF (2.7 MB)
  • 64 Views
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Article
Surface biofunctionalized CdS and ZnS quantum dot nanoconjugates for nanomedicine and oncology: to be or not to be nanotoxic?
Alexandra AP Mansur, Herman S Mansur, Sandhra M de Carvalho, Zélia IP Lobato, Maria IMC Guedes & Maria F Leite
Pages: 4669-4690
Published online: 14 Sep 2016
AbstractforSurface biofunctionalized CdS and ZnS quantum dot nanoconjugates for nanomedicine and oncology: to be or not to be nanotoxic? | Full Text | References | PDF (6.6 MB)
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Article
Comparative study of proteasome inhibitory, synergistic antibacterial, synergistic anticandidal, and antioxidant activities of gold nanoparticles biosynthesized using fruit waste materials
Jayanta Kumar Patra & Kwang-Hyun Baek
Pages: 4691-4705
Published online: 14 Sep 2016
AbstractforComparative study of proteasome inhibitory, synergistic antibacterial, synergistic anticandidal, and antioxidant activities of gold nanoparticles biosynthesized using fruit waste materials | Full Text | References | PDF (2.8 MB)
  • 123 Views
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Article
Fabrication of gelatin methacrylate/nanohydroxyapatite microgel arrays for periodontal tissue regeneration
Xi Chen, Shizhu Bai, Bei Li, Huan Liu, Guofeng Wu, Sha Liu & Yimin Zhao
Pages: 4707-4718
Published online: 14 Sep 2016
AbstractforFabrication of gelatin methacrylate/nanohydroxyapatite microgel arrays for periodontal tissue regeneration | Full Text | References | PDF (5.2 MB)
  • 194 Views
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Article
The synergistic effect of TiO2 nanoporous modification and platelet-rich plasma treatment on titanium-implant stability in ovariectomized rats
Nan Jiang, Pinggong Du, Weidong Qu, Lin Li, Zhonghao Liu & Songsong Zhu
Pages: 4719-4733
Published online: 28 Feb 2023
AbstractforThe synergistic effect of TiO2 nanoporous modification and platelet-rich plasma treatment on titanium-implant stability in ovariectomized rats | Full Text | References | PDF (12.3 MB)
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Article
Monte Carlo and analytic simulations in nanoparticle-enhanced radiation therapy
Autumn D Paro, Mainul Hossain, Thomas J Webster & Ming Su
Pages: 4735-4741
Published online: 16 Sep 2016
AbstractforMonte Carlo and analytic simulations in nanoparticle-enhanced radiation therapy | Full Text | References | PDF (1.1 MB)
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Review

Review Article
Demineralization–remineralization dynamics in teeth and bone
Ensanya Ali Abou Neel, Anas Aljabo, Adam Strange, Salwa Ibrahim, Melanie Coathup, Anne M Young, Laurent Bozec & Vivek Mudera
Pages: 4743-4763
Published online: 28 Feb 2023
AbstractforDemineralization–remineralization dynamics in teeth and bone | Full Text | References | PDF (729 KB)
  • 1648 Views
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Original Research

Article
Multifunctional nanocomposite based on halloysite nanotubes for efficient luminescent bioimaging and magnetic resonance imaging
Tao Zhou, Lei Jia, Yi-Feng Luo, Jun Xu, Ru-Hua Chen, Zhi-Jun Ge, Tie-Liang Ma, Hong Chen & Tao-Feng Zhu
Pages: 4765-4776
Published online: 19 Sep 2016
AbstractforMultifunctional nanocomposite based on halloysite nanotubes for efficient luminescent bioimaging and magnetic resonance imaging | Full Text | References | PDF (4.1 MB)
  • 61 Views
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Article
Functionalized immunostimulating complexes with protein A via lipid vinyl sulfones to deliver cancer drugs to trastuzumab-resistant HER2-overexpressing breast cancer cells
Fernando Rodríguez-Serrano, Nuria Mut-Salud, Teresa Cruz-Bustos, Mercedes Gomez-Samblas, Esther Carrasco, Jose Manuel Garrido, F Javier López-Jaramillo, Francisco Santoyo-Gonzalez & Antonio Osuna
Pages: 4777-4785
Published online: 28 Feb 2023
AbstractforFunctionalized immunostimulating complexes with protein A via lipid vinyl sulfones to deliver cancer drugs to trastuzumab-resistant HER2-overexpressing breast cancer cells | Full Text | References | PDF (2 MB)
  • 62 Views
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Article
Microstructural, spectroscopic, and antibacterial properties of silver-based hybrid nanostructures biosynthesized using extracts of coriander leaves and seeds
Carlos Luna, Enrique Díaz Barriga-Castro, Alberto Gómez-Treviño, Nuria O Núñez & Raquel Mendoza-Reséndez
Pages: 4787-4798
Published online: 20 Sep 2016
AbstractforMicrostructural, spectroscopic, and antibacterial properties of silver-based hybrid nanostructures biosynthesized using extracts of coriander leaves and seeds | Full Text | References | PDF (3.3 MB)
  • 108 Views
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Article
Stealth, biocompatible monoolein-based lyotropic liquid crystalline nanoparticles for enhanced aloe-emodin delivery to breast cancer cells: in vitro and in vivo studies
May S Freag, Yosra SR Elnaggar, Doaa A Abdelmonsif & Ossama Y Abdallah
Pages: 4799-4818
Published online: 20 Sep 2016
AbstractforStealth, biocompatible monoolein-based lyotropic liquid crystalline nanoparticles for enhanced aloe-emodin delivery to breast cancer cells: in vitro and in vivo studies | Full Text | References | PDF (2.6 MB)
  • 137 Views
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Review

Review Article
TiO2 nanotube platforms for smart drug delivery: a review
Qun Wang, Jian-Ying Huang, Hua-Qiong Li, Zhong Chen, Allan Zi-Jian Zhao, Yi Wang, Ke-Qin Zhang, Hong-Tao Sun, Salem S Al-Deyab & Yue-Kun Lai
Pages: 4819-4834
Published online: 21 Sep 2016
AbstractforTiO2 nanotube platforms for smart drug delivery: a review | Full Text | References | PDF (3.4 MB)
  • 323 Views
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Review Article
Viruses as nanomedicine for cancer
Narayanasamy Badrinath, Jeong Heo & So Young Yoo
Pages: 4835-4847
Published online: 21 Sep 2016
AbstractforViruses as nanomedicine for cancer | Full Text | References | PDF (1.8 MB)
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Original Research

Article
Treatment of natural mammary gland tumors in canines and felines using gold nanorods-assisted plasmonic photothermal therapy to induce tumor apoptosis
Moustafa R K Ali, Ibrahim M Ibrahim, Hala R Ali, Salah A Selim & Mostafa A El-Sayed
Pages: 4849-4863
Published online: 22 Sep 2016
AbstractforTreatment of natural mammary gland tumors in canines and felines using gold nanorods-assisted plasmonic photothermal therapy to induce tumor apoptosis | Full Text | References | PDF (4.6 MB)
  • 128 Views
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Article
Multimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities
Stefania Biffi, Luca Petrizza, Chiara Garrovo, Enrico Rampazzo, Laura Andolfi, Pierangela Giustetto, Ivaylo Nikolov, Gabor Kurdi, Miltcho Boyanov Danailov, Giorgio Zauli, Paola Secchiero & Luca Prodi
Pages: 4865-4874
Published online: 22 Sep 2016
AbstractforMultimodal near-infrared-emitting PluS Silica nanoparticles with fluorescent, photoacoustic, and photothermal capabilities | Full Text | References | PDF (1.7 MB)
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Article
Sustained release of hepatocyte growth factor by cationic self-assembling peptide/heparin hybrid hydrogel improves β-cell survival and function through modulating inflammatory response
Shuyun Liu, Lanlan Zhang, Jingqiu Cheng, Yanrong Lu & Jingping Liu
Pages: 4875-4890
Published online: 28 Feb 2023
AbstractforSustained release of hepatocyte growth factor by cationic self-assembling peptide/heparin hybrid hydrogel improves β-cell survival and function through modulating inflammatory response | Full Text | References | PDF (6 MB)
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Article
Evaluation of optimum conditions for pachyman encapsulated in poly(d,l-lactic acid) nanospheres by response surface methodology and results of a related in vitro study
Sisi Zheng, Li Luo, Ruonan Bo, Zhenguang Liu, Jie Xing, Yale Niu, Yuanliang Hu, Jiaguo Liu & Deyun Wang
Pages: 4891-4904
Published online: 28 Feb 2023
AbstractforEvaluation of optimum conditions for pachyman encapsulated in poly(d,l-lactic acid) nanospheres by response surface methodology and results of a related in vitro study | Full Text | References | PDF (3.3 MB)
  • 38 Views
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Article
Photodynamic therapy of tumors with pyropheophorbide-a-loaded polyethylene glycol–poly(lactic-co-glycolic acid) nanoparticles
Hui Liu, Mei Zhao, Jin Wang, Mingpei Pang, Zhenzhou Wu, Liqing Zhao, Zhinan Yin & Zhangyong Hong
Pages: 4905-4918
Published online: 27 Sep 2016
AbstractforPhotodynamic therapy of tumors with pyropheophorbide-a-loaded polyethylene glycol–poly(lactic-co-glycolic acid) nanoparticles | Full Text | References | PDF (7.5 MB)
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Article
Preparation and evaluation of a self-nanoemulsifying drug delivery system loaded with Akebia saponin D–phospholipid complex
Jinyang Shen, Jianping Bi, Hongli Tian, Ye Jin, Yuan Wang, Xiaolin Yang, Zhonglin Yang, Junping Kou & Fei Li
Pages: 4919-4929
Published online: 28 Feb 2023
AbstractforPreparation and evaluation of a self-nanoemulsifying drug delivery system loaded with Akebia saponin D–phospholipid complex | Full Text | References | PDF (2.3 MB)
  • 129 Views
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Article
Chitosan-based nanoparticles for survivin targeted siRNA delivery in breast tumor therapy and preventing its metastasis
Ping Sun, Wei Huang, Mingji Jin, Qiming Wang, Bo Fan, Lin Kang & Zhonggao Gao
Pages: 4931-4945
Published online: 27 Sep 2016
AbstractforChitosan-based nanoparticles for survivin targeted siRNA delivery in breast tumor therapy and preventing its metastasis | Full Text | References | PDF (3.3 MB)
  • 108 Views
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Article
Suppression of synaptic plasticity by fullerenol in rat hippocampus in vitro
Xin-Xing Wang, Ying-Ying Zha, Bo Yang, Lin Chen & Ming Wang
Pages: 4947-4955
Published online: 28 Feb 2023
AbstractforSuppression of synaptic plasticity by fullerenol in rat hippocampus in vitro | Full Text | References | PDF (2.1 MB)
  • 48 Views
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Article
A nanoporous surface is essential for glomerular podocyte differentiation in three-dimensional culture
Cristina Zennaro, Maria Pia Rastaldi, Gerald James Bakeine, Riccarda Delfino, Federica Tonon, Rossella Farra, Gabriele Grassi, Mary Artero, Massimo Tormen & Michele Carraro
Pages: 4957-4973
Published online: 30 Sep 2016
AbstractforA nanoporous surface is essential for glomerular podocyte differentiation in three-dimensional culture | Full Text | References | PDF (8 MB)
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Article
Antidepressant effects of curcumin and HU-211 coencapsulated solid lipid nanoparticles against corticosterone-induced cellular and animal models of major depression
Xiaolie He, Yanjing Zhu, Mei Wang, Guoxin Jing, Rongrong Zhu & Shilong Wang
Pages: 4975-4990
Published online: 28 Feb 2023
AbstractforAntidepressant effects of curcumin and HU-211 coencapsulated solid lipid nanoparticles against corticosterone-induced cellular and animal models of major depression | Full Text | References | PDF (3 MB)
  • 118 Views
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Article
Pluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells
Xiang-Jun Tang, Kuan-Ming Huang, Hui Gui, Jun-Jie Wang, Jun-Ti Lu, Long-Jun Dai, Li Zhang & Gang Wang
Pages: 4991-5002
Published online: 28 Feb 2023
AbstractforPluronic-based micelle encapsulation potentiates myricetin-induced cytotoxicity in human glioblastoma cells | Full Text | References | PDF (1.7 MB)
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Article
Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma
Peidang Liu, Haizhen Jin, Zhirui Guo, Jun Ma, Jing Zhao, Dongdong Li, Hao Wu & Ning Gu
Pages: 5003-5014
Published online: 03 Oct 2016
AbstractforSilver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma | Full Text | References | PDF (6.3 MB)
  • 183 Views
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Article
Antimicrobial potential of green synthesized CeO2 nanoparticles from Olea europaea leaf extract
Qaisar Maqbool, Mudassar Nazar, Sania Naz, Talib Hussain, Nyla Jabeen, Rizwan Kausar, Sadaf Anwaar, Fazal Abbas & Tariq Jan
Pages: 5015-5025
Published online: 04 Oct 2016
AbstractforAntimicrobial potential of green synthesized CeO2 nanoparticles from Olea europaea leaf extract | Full Text | References | PDF (3.8 MB)
  • 472 Views
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Article
Docosahexaenoic acid liposomes for targeting chronic inflammatory diseases and cancer: an in vitro assessment
Amr Alaarg, Nan Yeun Jordan, Johan JF Verhoef, Josbert M Metselaar, Gert Storm & Robbert J Kok
Pages: 5027-5040
Published online: 05 Oct 2016
AbstractforDocosahexaenoic acid liposomes for targeting chronic inflammatory diseases and cancer: an in vitro assessment | Full Text | References | PDF (2.7 MB)
  • 112 Views
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Article
Nanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells
Rosa Di Liddo, Paola Aguiari, Silvia Barbon, Thomas Bertalot, Amit Mandoli, Alessia Tasso, Sandra Schrenk, Laura Iop, Alessandro Gandaglia, Pier Paolo Parnigotto, Maria Teresa Conconi & Gino Gerosa
Pages: 5041-5055
Published online: 12 Oct 2016
AbstractforNanopatterned acellular valve conduits drive the commitment of blood-derived multipotent cells | Full Text | References | PDF (4.4 MB)
  • 66 Views
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Article
Alkaline nanoparticle coatings improve resin bonding of 10-methacryloyloxydecyldihydrogenphosphate-conditioned zirconia
Mengke Qian, Zhicen Lu, Chen Chen, Huaiqin Zhang & Haifeng Xie
Pages: 5057-5066
Published online: 28 Feb 2023
AbstractforAlkaline nanoparticle coatings improve resin bonding of 10-methacryloyloxydecyldihydrogenphosphate-conditioned zirconia | Full Text | References | PDF (3.2 MB)
  • 61 Views
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Article
Development and evaluation of nanostructured lipid carrier-based hydrogel for topical delivery of 5-fluorouracil
Paruvathanahalli Siddalingam Rajinikanth & Jestin Chellian
Pages: 5067-5077
Published online: 05 Oct 2016
AbstractforDevelopment and evaluation of nanostructured lipid carrier-based hydrogel for topical delivery of 5-fluorouracil | Full Text | References | PDF (805.5 KB)
  • 264 Views
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Article
Visual tracing of diffusion and biodistribution for amphiphilic cationic nanoparticles using photoacoustic imaging after ex vivo intravitreal injections
Xu Xu, Zhaokang Xu, Junyi Liu, Zhaoliang Zhang, Hao Chen, Xingyi Li & Shuai Shi
Pages: 5079-5086
Published online: 05 Oct 2016
AbstractforVisual tracing of diffusion and biodistribution for amphiphilic cationic nanoparticles using photoacoustic imaging after ex vivo intravitreal injections | Full Text | References | PDF (2.9 MB)
  • 60 Views
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Article
Electrospinning of calcium phosphate-poly (d,l-lactic acid) nanofibers for sustained release of water-soluble drug and fast mineralization
Qi-Wei Fu, Yun-Peng Zi, Wei Xu, Rong Zhou, Zhu-Yun Cai, Wei-Jie Zheng, Feng Chen & Qi-Rong Qian
Pages: 5087-5097
Published online: 06 Oct 2016
AbstractforElectrospinning of calcium phosphate-poly (d,l-lactic acid) nanofibers for sustained release of water-soluble drug and fast mineralization | Full Text | References | PDF (9.1 MB)
  • 72 Views
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Article
Recombinant epidermal growth factor-like domain-1 from coagulation factor VII functionalized iron oxide nanoparticles for targeted glioma magnetic resonance imaging
Heng Liu, Xiao Chen, Wei Xue, Chengchao Chu, Yu Liu, Haipeng Tong, Xuesong Du, Tian Xie, Gang Liu & Weiguo Zhang
Pages: 5099-5108
Published online: 06 Oct 2016
AbstractforRecombinant epidermal growth factor-like domain-1 from coagulation factor VII functionalized iron oxide nanoparticles for targeted glioma magnetic resonance imaging | Full Text | References | PDF (2.7 MB)
  • 50 Views
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Article
Biodegradable mixed MPEG-SS-2SA/TPGS micelles for triggered intracellular release of paclitaxel and reversing multidrug resistance
Kai Dong, Yan Yan, Pengchong Wang, Xianpeng Shi, Lu Zhang, Ke Wang, Jianfeng Xing & Yalin Dong
Pages: 5109-5123
Published online: 06 Oct 2016
AbstractforBiodegradable mixed MPEG-SS-2SA/TPGS micelles for triggered intracellular release of paclitaxel and reversing multidrug resistance | Full Text | References | PDF (2.3 MB)
  • 56 Views
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Article
GE11 peptide modified and reduction-responsive hyaluronic acid-based nanoparticles induced higher efficacy of doxorubicin for breast carcinoma therapy
Danrong Hu, Omar Mezghrani, Lei Zhang, Yi Chen, Xue Ke & Tianyuan Ci
Pages: 5125-5147
Published online: 07 Oct 2016
AbstractforGE11 peptide modified and reduction-responsive hyaluronic acid-based nanoparticles induced higher efficacy of doxorubicin for breast carcinoma therapy | Full Text | References | PDF (4.9 MB)
  • 121 Views
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Article
Increasing roughness of the human breast cancer cell membrane through incorporation of gold nanoparticles
C Lara-Cruz, JE Jiménez-Salazar, E Ramón-Gallegos, P Damian-Matsumura & N Batina
Pages: 5149-5161
Published online: 07 Oct 2016
AbstractforIncreasing roughness of the human breast cancer cell membrane through incorporation of gold nanoparticles | Full Text | References | PDF (4.6 MB)
  • 90 Views
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Review

Review Article
Carbon nanotubes as cancer therapeutic carriers and mediators
Kuk Hui Son, Jeong Hee Hong & Jin Woo Lee
Pages: 5163-5185
Published online: 07 Oct 2016
AbstractforCarbon nanotubes as cancer therapeutic carriers and mediators | Full Text | References | PDF (2.4 MB)
  • 229 Views
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Original Research

Article
Cytotoxic effects of ZnO nanoparticles on mouse testicular cells
Zhe Han, Qi Yan, Wei Ge, Zhi-Guo Liu, Sangiliyandi Gurunathan, Massimo De Felici, Wei Shen & Xi-Feng Zhang
Pages: 5187-5203
Published online: 11 Oct 2016
AbstractforCytotoxic effects of ZnO nanoparticles on mouse testicular cells | Full Text | References | PDF (3.8 MB)
  • 130 Views
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Article
Synergistic effects of A-B-C-type amphiphilic copolymer on reversal of drug resistance in MCF-7/ADR breast carcinoma
Lu Zhang, Jiafei Lu & Liyan Qiu
Pages: 5205-5220
Published online: 11 Oct 2016
AbstractforSynergistic effects of A-B-C-type amphiphilic copolymer on reversal of drug resistance in MCF-7/ADR breast carcinoma | Full Text | References | PDF (1.6 MB)
  • 66 Views
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Article
Comparison of cellular effects of starch-coated SPIONs and poly(lactic-co-glycolic acid) matrix nanoparticles on human monocytes
Dominik Gonnissen, Ying Qu, Klaus Langer, Cengiz Öztürk, Yuliang Zhao, Chunying Chen, Guiscard Seebohm, Martina Düfer, Harald Fuchs, Hans-Joachim Galla & Kristina Riehemann
Pages: 5221-5236
Published online: 14 Oct 2016
AbstractforComparison of cellular effects of starch-coated SPIONs and poly(lactic-co-glycolic acid) matrix nanoparticles on human monocytes | Full Text | References | PDF (3.2 MB)
  • 59 Views
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Article
New optical sensing technique of tissue viability and blood flow based on nanophotonic iterative multi-plane reflectance measurements
Inbar Yariv, Menashe Haddad, Hamootal Duadi, Menachem Motiei & Dror Fixler
Pages: 5237-5244
Published online: 28 Feb 2023
AbstractforNew optical sensing technique of tissue viability and blood flow based on nanophotonic iterative multi-plane reflectance measurements | Full Text | References | PDF (1.3 MB)
  • 45 Views
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Article
Intracellular redox-responsive nanocarrier for plasmid delivery: in vitro characterization and in vivo studies in mice
Lifen Zhang, Yushun Zhang, Zhenzhen Chen & Yuling He
Pages: 5245-5256
Published online: 11 Oct 2016
AbstractforIntracellular redox-responsive nanocarrier for plasmid delivery: in vitro characterization and in vivo studies in mice | Full Text | References | PDF (3.3 MB)
  • 44 Views
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Article
Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling
Caixia Guo, Man Yang, Li Jing, Ji Wang, Yang Yu, Yang Li, Junchao Duan, Xianqing Zhou, Yanbo Li & Zhiwei Sun
Pages: 5257-5276
Published online: 11 Oct 2016
AbstractforAmorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling | Full Text | References | PDF (10.8 MB)
  • 117 Views
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Article
Co-delivery of doxorubicin and recombinant plasmid pHSP70-Plk1-shRNA by bacterial magnetosomes for osteosarcoma therapy
Li Cheng, Youqun Ke, Shuisheng Yu & Juehua Jing
Pages: 5277-5286
Published online: 25 Oct 2016
AbstractforCo-delivery of doxorubicin and recombinant plasmid pHSP70-Plk1-shRNA by bacterial magnetosomes for osteosarcoma therapy | Full Text | References | PDF (3.7 MB)
  • 61 Views
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Review

Review Article
RNA interference-based nanosystems for inflammatory bowel disease therapy
Jian Guo, Xiaojing Jiang & Shuangying Gui
Pages: 5287-5310
Published online: 12 Oct 2016
AbstractforRNA interference-based nanosystems for inflammatory bowel disease therapy | Full Text | References | PDF (1.5 MB)
  • 105 Views
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Original Research

Article
Increased survival rate by local release of diclofenac in a murine model of recurrent oral carcinoma
Olga Maria Will, Nicolai Purcz, Athena Chalaris, Carola Heneweer, Susann Boretius, Larissa Purcz, Lila Nikkola, Nureddin Ashammakhi, Holger Kalthoff, Claus-Christian Glüer, Jörg Wiltfang, Yahya Açil & Sanjay Tiwari
Pages: 5311-5321
Published online: 12 Oct 2016
AbstractforIncreased survival rate by local release of diclofenac in a murine model of recurrent oral carcinoma | Full Text | References | PDF (898.7 KB)
  • 135 Views
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Article
Increased radiosensitivity of colorectal tumors with intra-tumoral injection of low dose of gold nanoparticles
Minghan Shi, Benoit Paquette, Thititip Thippayamontri, Louis Gendron, Brigitte Guérin & Léon Sanche
Pages: 5323-5333
Published online: 12 Oct 2016
AbstractforIncreased radiosensitivity of colorectal tumors with intra-tumoral injection of low dose of gold nanoparticles | Full Text | References | PDF (2.2 MB)
  • 57 Views
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Article
Real-time colorimetric detection of DNA methylation of the PAX1 gene in cervical scrapings for cervical cancer screening with thiol-labeled PCR primers and gold nanoparticles
Jin Huang, Yu-Ligh Liou, Ya-Nan Kang, Zhi-Rong Tan, Ming-Jing Peng & Hong-Hao Zhou
Pages: 5335-5347
Published online: 28 Feb 2023
AbstractforReal-time colorimetric detection of DNA methylation of the PAX1 gene in cervical scrapings for cervical cancer screening with thiol-labeled PCR primers and gold nanoparticles | Full Text | References | PDF (2.6 MB)
  • 66 Views
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Article
Effects of nanoporous anodic titanium oxide on human adipose derived stem cells
Katarzyna Malec, Joanna Góralska, Magdalena Hubalewska-Mazgaj, Paulina Głowacz, Magdalena Jarosz, Pawel Brzewski, Grzegorz D Sulka, Marian Jaskuła & Iwona Wybrańska
Pages: 5349-5360
Published online: 14 Oct 2016
AbstractforEffects of nanoporous anodic titanium oxide on human adipose derived stem cells | Full Text | References | PDF (2 MB)
  • 54 Views
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Article
Hepatitis C virus E2 protein encapsulation into poly d, l-lactic-co-glycolide microspheres could induce mice cytotoxic T-cell response
Piyachat Roopngam, Kewei Liu, Lin Mei, Yi Zheng, Xianbing Zhu, Hsiang-I Tsai & Laiqiang Huang
Pages: 5361-5370
Published online: 14 Oct 2016
AbstractforHepatitis C virus E2 protein encapsulation into poly d, l-lactic-co-glycolide microspheres could induce mice cytotoxic T-cell response | Full Text | References | PDF (1.4 MB)
  • 46 Views
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Article
Optimizing superparamagnetic iron oxide nanoparticles as drug carriers using an in vitro blood–brain barrier model
Di Shi, Gujie Mi, Soumya Bhattacharya, Suprabha Nayar & Thomas J Webster
Pages: 5371-5379
Published online: 17 Oct 2016
AbstractforOptimizing superparamagnetic iron oxide nanoparticles as drug carriers using an in vitro blood–brain barrier model | Full Text | References | PDF (3.5 MB)
  • 128 Views
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Review

Review Article
Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier
Débora B Vieira & Lionel F Gamarra
Pages: 5381-5414
Published online: 18 Oct 2016
AbstractforGetting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier | Full Text | References | PDF (6.1 MB)
  • 869 Views
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Original Research

Article
Decoration of pH-sensitive copolymer micelles with tumor-specific peptide for enhanced cellular uptake of doxorubicin
Qing Chen, Miaomiao Long, Lipeng Qiu, Mengqin Zhu, Zhen Li, Mingxi Qiao, Haiyang Hu, Xiuli Zhao & Dawei Chen
Pages: 5415-5427
Published online: 18 Oct 2016
AbstractforDecoration of pH-sensitive copolymer micelles with tumor-specific peptide for enhanced cellular uptake of doxorubicin | Full Text | References | PDF (4.1 MB)
  • 46 Views
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Article
Daunorubicin and gambogic acid coloaded cysteamine-CdTe quantum dots minimizing the multidrug resistance of lymphoma in vitro and in vivo
Yi Zhou, Ruju Wang, Bing Chen, Dan Sun, Yong Hu & Peipei Xu
Pages: 5429-5442
Published online: 18 Oct 2016
AbstractforDaunorubicin and gambogic acid coloaded cysteamine-CdTe quantum dots minimizing the multidrug resistance of lymphoma in vitro and in vivo | Full Text | References | PDF (2.4 MB)
  • 45 Views
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Article
Core–shell magnetic nanoparticles display synergistic antibacterial effects against Pseudomonas aeruginosa and Staphylococcus aureus when combined with cathelicidin LL-37 or selected ceragenins
Katarzyna Niemirowicz, Ewelina Piktel, Agnieszka Z Wilczewska, Karolina H Markiewicz, Bonita Durnaś, Marzena Wątek, Irena Puszkarz, Marta Wróblewska, Wiesława Niklińska, Paul B Savage & Robert Bucki
Pages: 5443-5455
Published online: 19 Oct 2016
AbstractforCore–shell magnetic nanoparticles display synergistic antibacterial effects against Pseudomonas aeruginosa and Staphylococcus aureus when combined with cathelicidin LL-37 or selected ceragenins | Full Text | References | PDF (2.6 MB)
  • 179 Views
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Article
Lx2-32c–loaded polymeric micelles with small size for intravenous drug delivery and their inhibitory effect on tumor growth and metastasis in clinically associated 4T1 murine breast cancer
Li-qing Chen, Wei Huang, Zhong-gao Gao, Wei-shuo Fang & Ming-ji Jin
Pages: 5457-5472
Published online: 19 Oct 2016
AbstractforLx2-32c–loaded polymeric micelles with small size for intravenous drug delivery and their inhibitory effect on tumor growth and metastasis in clinically associated 4T1 murine breast cancer | Full Text | References | PDF (4.9 MB)
  • 39 Views
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Article
Graphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway
Xinxin Yan, Wen Yang, Zengwu Shao, Shuhua Yang & Xianzhe Liu
Pages: 5473-5484
Published online: 28 Feb 2023
AbstractforGraphene/single-walled carbon nanotube hybrids promoting osteogenic differentiation of mesenchymal stem cells by activating p38 signaling pathway | Full Text | References | PDF (2.6 MB)
  • 43 Views
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Article
Efficient delivery of Notch1 siRNA to SKOV3 cells by cationic cholesterol derivative-based liposome
Yun-Chun Zhao, Li Zhang, Shi-Sen Feng, Lu Hong, Hai-Li Zheng, Li-Li Chen, Xiao-Ling Zheng, Yi-Qing Ye, Meng-Dan Zhao, Wen-Xi Wang & Cai-Hong Zheng
Pages: 5485-5496
Published online: 20 Oct 2016
AbstractforEfficient delivery of Notch1 siRNA to SKOV3 cells by cationic cholesterol derivative-based liposome | Full Text | References | PDF (3.3 MB)
  • 78 Views
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Article
Highly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite particles
Minhong Jeun, Sungwook Park, Hakho Lee & Kwan Hyi Lee
Pages: 5497-5503
Published online: 21 Oct 2016
AbstractforHighly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite particles | Full Text | References | PDF (1.5 MB)
  • 59 Views
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Article
CD20 monoclonal antibody targeted nanoscale drug delivery system for doxorubicin chemotherapy: an in vitro study of cell lysis of CD20-positive Raji cells
Shuang Jiang, Xiaobo Wang, Zhiran Zhang, Lan Sun, Yunzhu Pu, Hongjuan Yao, Jingcao Li, Yan Liu, Yingge Zhang & Weijing Zhang
Pages: 5505-5518
Published online: 02 Nov 2016
AbstractforCD20 monoclonal antibody targeted nanoscale drug delivery system for doxorubicin chemotherapy: an in vitro study of cell lysis of CD20-positive Raji cells | Full Text | References | PDF (6.9 MB)
  • 76 Views
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Article
Quantum dot-based immunofluorescent imaging and quantitative detection of TOP2A and prognostic value in triple-negative breast cancer
Hongmei Zheng, Xiang Li, Chuang Chen, Jian Chen, Jinzhong Sun, Si Sun, Liting Jin, Juanjuan Li, Shengrong Sun & Xinhong Wu
Pages: 5519-5529
Published online: 21 Oct 2016
AbstractforQuantum dot-based immunofluorescent imaging and quantitative detection of TOP2A and prognostic value in triple-negative breast cancer | Full Text | References | PDF (4 MB)
  • 103 Views
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Article
Novel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies
Yosra SR Elnaggar, Sara M Talaat, Mohammed Bahey-El-Din & Ossama Y Abdallah
Pages: 5531-5547
Published online: 25 Oct 2016
AbstractforNovel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies | Full Text | References | PDF (4.5 MB)
  • 169 Views
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Article
Promotion of the transdermal delivery of protein drugs by N-trimethyl chitosan nanoparticles combined with polypropylene electret
Ye Tu, Xinxia Wang, Ying Lu, He Zhang, Yuan Yu, Yan Chen, Junjie Liu, Zhiguo Sun, Lili Cui, Jing Gao & Yanqiang Zhong
Pages: 5549-5561
Published online: 25 Oct 2016
AbstractforPromotion of the transdermal delivery of protein drugs by N-trimethyl chitosan nanoparticles combined with polypropylene electret | Full Text | References | PDF (3.6 MB)
  • 53 Views
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Article
Biofunctionalization of silicone rubber with microgroove-patterned surface and carbon-ion implantation to enhance biocompatibility and reduce capsule formation
Ze-yuan Lei, Ting Liu, Wei-juan Li, Xiao-hua Shi & Dong-li Fan
Pages: 5563-5572
Published online: 25 Oct 2016
AbstractforBiofunctionalization of silicone rubber with microgroove-patterned surface and carbon-ion implantation to enhance biocompatibility and reduce capsule formation | Full Text | References | PDF (4.2 MB)
  • 75 Views
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Article
Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing
Yusuke Doi, Amr S Abu Lila, Haruna Matsumoto, Tomoko Okada, Taro Shimizu & Tatsuhiro Ishida
Pages: 5573-5582
Published online: 25 Oct 2016
AbstractforImprovement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing | Full Text | References | PDF (1.4 MB)
  • 55 Views
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Article
Self-assembling peptide nanofibers containing phenylalanine for the controlled release of 5-fluorouracil
Narayanan Ashwanikumar, Nisha Asok Kumar, Padma S Saneesh Babu, Krishnankutty C Sivakumar, Mithun Varghese Vadakkan, Parvathi Nair, Ilamathi Hema Saranya, Sivakumari Asha Nair & Gopalakrishnapillai S Vinod Kumar
Pages: 5583-5594
Published online: 25 Oct 2016
AbstractforSelf-assembling peptide nanofibers containing phenylalanine for the controlled release of 5-fluorouracil | Full Text | References | PDF (4.2 MB)
  • 124 Views
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Article
RGD-conjugated mesoporous silica-encapsulated gold nanorods enhance the sensitization of triple-negative breast cancer to megavoltage radiation therapy
Ning Zhao, Zhangru Yang, Bingxin Li, Jin Meng, Zeliang Shi, Ping Li & Shen Fu
Pages: 5595-5610
Published online: 27 Oct 2016
AbstractforRGD-conjugated mesoporous silica-encapsulated gold nanorods enhance the sensitization of triple-negative breast cancer to megavoltage radiation therapy | Full Text | References | PDF (7.4 MB)
  • 71 Views
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Article
Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties
Saori Nagao, Kazuaki Taguchi, Hiromi Sakai, Keishi Yamasaki, Hiroshi Watanabe, Masaki Otagiri & Toru Maruyama
Pages: 5611-5620
Published online: 27 Oct 2016
AbstractforCarbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties | Full Text | References | PDF (1.6 MB)
  • 92 Views
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Article
Raspberry-like poly(γ-glutamic acid) hydrogel particles for pH-dependent cell membrane passage and controlled cytosolic delivery of antitumor drugs
Sun-Hee Cho, Ji Hyeon Hong, Young-Woock Noh, Eunji Lee, Chang-Soo Lee & Yong Taik Lim
Pages: 5621-5632
Published online: 27 Oct 2016
AbstractforRaspberry-like poly(γ-glutamic acid) hydrogel particles for pH-dependent cell membrane passage and controlled cytosolic delivery of antitumor drugs | Full Text | References | PDF (3.4 MB)
  • 64 Views
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Article
Influence of incorporation of ZrO2 nanoparticles on the repair strength of polymethyl methacrylate denture bases
Mohammed M Gad, Ahmed Rahoma, Ahmad M Al-Thobity & Aws S ArRejaie
Pages: 5633-5643
Published online: 27 Oct 2016
AbstractforInfluence of incorporation of ZrO2 nanoparticles on the repair strength of polymethyl methacrylate denture bases | Full Text | References | PDF (2 MB)
  • 252 Views
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Review

Review Article
Ligand-based targeted therapy: a novel strategy for hepatocellular carcinoma
Min Li, Weiyue Zhang, Birong Wang, Yang Gao, Zifang Song & Qi Chang Zheng
Pages: 5645-5669
Published online: 31 Oct 2016
AbstractforLigand-based targeted therapy: a novel strategy for hepatocellular carcinoma | Full Text | References | PDF (1.3 MB)
  • 246 Views
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Original Research

Article
Noninvasive monitoring of early antiangiogenic therapy response in human nasopharyngeal carcinoma xenograft model using MRI with RGD-conjugated ultrasmall superparamagnetic iron oxide nanoparticles
Yanfen Cui, Caiyuan Zhang, Ran Luo, Huanhuan Liu, Zhongyang Zhang, Tianyong Xu, Yong Zhang & Dengbin Wang
Pages: 5671-5682
Published online: 14 Nov 2016
AbstractforNoninvasive monitoring of early antiangiogenic therapy response in human nasopharyngeal carcinoma xenograft model using MRI with RGD-conjugated ultrasmall superparamagnetic iron oxide nanoparticles | Full Text | References | PDF (6.4 MB)
  • 62 Views
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Article
Biogenesis of silver nanoparticles using endophytic fungus Pestalotiopsis microspora and evaluation of their antioxidant and anticancer activities
Vasudeva Reddy Netala, Murali Satyanarayana Bethu, Bobbu Pushpalatha, Vijaya Bhaskar Baki, Sani Aishwarya, J Venkateswara Rao & Vijaya Tartte
Pages: 5683-5696
Published online: 28 Feb 2023
AbstractforBiogenesis of silver nanoparticles using endophytic fungus Pestalotiopsis microspora and evaluation of their antioxidant and anticancer activities | Full Text | References | PDF (3.5 MB)
  • 263 Views
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Article
Formulation, characterization and tissue distribution of a novel pH-sensitive long-circulating liposome-based theranostic suitable for molecular imaging and drug delivery
Yin Duan, Lihui Wei, Julia Petryk & Terrence D Ruddy
Pages: 5697-5708
Published online: 01 Nov 2016
AbstractforFormulation, characterization and tissue distribution of a novel pH-sensitive long-circulating liposome-based theranostic suitable for molecular imaging and drug delivery | Full Text | References | PDF (1.7 MB)
  • 77 Views
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Article
Salvianolic acid B protects against myocardial damage caused by nanocarrier TiO2; and synergistic anti-breast carcinoma effect with curcumin via codelivery system of folic acid-targeted and polyethylene glycol-modified TiO2 nanoparticles
Lingling Ding, Jiawei Li, Rui Huang, Zhidong Liu, Chunhua Li, Shaozi Yao, Jinyan Wang, Dongli Qi, Nan Li & Jiaxin Pi
Pages: 5709-5727
Published online: 02 Nov 2016
AbstractforSalvianolic acid B protects against myocardial damage caused by nanocarrier TiO2; and synergistic anti-breast carcinoma effect with curcumin via codelivery system of folic acid-targeted and polyethylene glycol-modified TiO2 nanoparticles | Full Text | References | PDF (5.8 MB)
  • 71 Views
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Article
Toll-like receptor 3-induced immune response by poly(d,l-lactide-co-glycolide) nanoparticles for dendritic cell-based cancer immunotherapy
Hee Dong Han, Yeongseon Byeon, Tae Heung Kang, In Duk Jung, Jeong-Won Lee, Byung Cheol Shin, Young Joo Lee, Anil K Sood & Yeong-Min Park
Pages: 5729-5742
Published online: 02 Nov 2016
AbstractforToll-like receptor 3-induced immune response by poly(d,l-lactide-co-glycolide) nanoparticles for dendritic cell-based cancer immunotherapy | Full Text | References | PDF (3.5 MB)
  • 100 Views
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Article
Antibacterial abilities and biocompatibilities of Ti–Ag alloys with nanotubular coatings
Xingwang Liu, Ang Tian, Junhua You, Hangzhou Zhang, Lin Wu, Xizhuang Bai, Zeming Lei, Xiaoguo Shi, Xiangxin Xue & Hanning Wang
Pages: 5743-5755
Published online: 28 Feb 2023
AbstractforAntibacterial abilities and biocompatibilities of Ti–Ag alloys with nanotubular coatings | Full Text | References | PDF (5.6 MB)
  • 76 Views
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Article
Nanomicelles loaded with doxorubicin and curcumin for alleviating multidrug resistance in lung cancer
Yue Gu, Jing Li, Yang Li, Lei Song, Dan Li, Liping Peng, Ying Wan & Shucheng Hua
Pages: 5757-5770
Published online: 03 Nov 2016
AbstractforNanomicelles loaded with doxorubicin and curcumin for alleviating multidrug resistance in lung cancer | Full Text | References | PDF (2.2 MB)
  • 117 Views
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Article
Gene-silencing effects of anti-survivin siRNA delivered by RGDV-functionalized nanodiamond carrier in the breast carcinoma cell line MCF-7
Yanzhao Bi, Yifan Zhang, Chunying Cui, Lulu Ren & Xueyun Jiang
Pages: 5771-5787
Published online: 04 Nov 2016
AbstractforGene-silencing effects of anti-survivin siRNA delivered by RGDV-functionalized nanodiamond carrier in the breast carcinoma cell line MCF-7 | Full Text | References | PDF (4.7 MB)
  • 73 Views
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Article
Biosynthesis, characterization, and evaluation of bioactivities of leaf extract-mediated biocompatible silver nanoparticles from an early tracheophyte, Pteris tripartita Sw.
Xavierravi Baskaran, Antony Varuvel Geo Vigila, Thangaraj Parimelazhagan, Doulathabad Muralidhara-Rao & Shouzhou Zhang
Pages: 5789-5806
Published online: 14 Nov 2016
AbstractforBiosynthesis, characterization, and evaluation of bioactivities of leaf extract-mediated biocompatible silver nanoparticles from an early tracheophyte, Pteris tripartita Sw. | Full Text | References | PDF (2.4 MB)
  • 211 Views
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Article
Development of PLGA-lipid nanoparticles with covalently conjugated indocyanine green as a versatile nanoplatform for tumor-targeted imaging and drug delivery
Yu Xin, Tie Liu & Chenlong Yang
Pages: 5807-5821
Published online: 04 Nov 2016
AbstractforDevelopment of PLGA-lipid nanoparticles with covalently conjugated indocyanine green as a versatile nanoplatform for tumor-targeted imaging and drug delivery | Full Text | References | PDF (2.7 MB)
  • 109 Views
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Article
Caveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells
Dan Shi, Yan Liu, Ronggang Xi, Wei Zou, Lijun Wu, Zhiran Zhang, Zhongyang Liu, Chao Qu, Baoli Xu & Xiaobo Wang
Pages: 5823-5835
Published online: 07 Nov 2016
AbstractforCaveolin-1 contributes to realgar nanoparticle therapy in human chronic myelogenous leukemia K562 cells | Full Text | References | PDF (2.2 MB)
  • 46 Views
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Article
Effects of intermolecular interactions on the stability of carbon nanotube–gold nanoparticle conjugates in solution
Lukasz Konczak, Jolanta Narkiewicz-Michalek, Giorgia Pastorin & Tomasz Panczyk
Pages: 5837-5849
Published online: 07 Nov 2016
AbstractforEffects of intermolecular interactions on the stability of carbon nanotube–gold nanoparticle conjugates in solution | Full Text | References | PDF (2.4 MB)
  • 38 Views
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Article
RETRACTED ARTICLE: The effect of dual-functional hyaluronic acid-vitamin E succinate micelles on targeting delivery of doxorubicin
Jinling Wang, Wenzhuan Ma, Qiang Guo, Ying Li, Zhongdong Hu, Zhixiang Zhu, Xiaohui Wang, Yunfang Zhao, Xingyun Chai & Pengfei Tu
Pages: 5851-5870
Published online: 07 Nov 2016
AbstractforRETRACTED ARTICLE: The effect of dual-functional hyaluronic acid-vitamin E succinate micelles on targeting delivery of doxorubicin | PDF (3.8 MB)
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Article
Apoptotic neuron-secreted HN12 inhibits cell apoptosis in Hirschsprung’s disease
Chunxia Du, Hua Xie, Rujin Zang, Ziyang Shen, Hongxing Li, Pingfa Chen, Xiaoqun Xu, Yankai Xia & Weibing Tang
Pages: 5871-5881
Published online: 07 Nov 2016
AbstractforApoptotic neuron-secreted HN12 inhibits cell apoptosis in Hirschsprung’s disease | Full Text | References | PDF (3 MB)
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Article
Modification of the surface of superparamagnetic iron oxide nanoparticles to enable their safe application in humans
Cindy Strehl, Lionel Maurizi, Timo Gaber, Paula Hoff, Thomas Broschard, A Robin Poole, Heinrich Hofmann & Frank Buttgereit
Pages: 5883-5896
Published online: 08 Nov 2016
AbstractforModification of the surface of superparamagnetic iron oxide nanoparticles to enable their safe application in humans | Full Text | References | PDF (5.1 MB)
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Article
Nucleic acid binding and other biomedical properties of artificial oligolysines
Giovanni N Roviello, Caterina Vicidomini, Vincenzo Costanzo & Valentina Roviello
Pages: 5897-5904
Published online: 10 Nov 2016
AbstractforNucleic acid binding and other biomedical properties of artificial oligolysines | Full Text | References | PDF (3 MB)
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Article
Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice
Yong Sze Ong, Latifah Saiful Yazan, Wei Keat Ng, Mustapha M Noordin, Sarah Sapuan, Jhi Biau Foo & Yin Sim Tor
Pages: 5905-5915
Published online: 09 Nov 2016
AbstractforAcute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice | Full Text | References | PDF (2.9 MB)
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Article
Sulfonate-modified phenylboronic acid-rich nanoparticles as a novel mucoadhesive drug delivery system for vaginal administration of protein therapeutics: improved stability, mucin-dependent release and effective intravaginal placement
ChunYan Li, ZhiGang Huang, ZheShuo Liu, LiQian Ci, ZhePeng Liu, Yu Liu, XueYing Yan & WeiYue Lu
Pages: 5917-5930
Published online: 10 Nov 2016
AbstractforSulfonate-modified phenylboronic acid-rich nanoparticles as a novel mucoadhesive drug delivery system for vaginal administration of protein therapeutics: improved stability, mucin-dependent release and effective intravaginal placement | Full Text | References | PDF (3.4 MB)
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Article
Biosynthesis of gold nanoparticles by the extreme bacterium Deinococcus radiodurans and an evaluation of their antibacterial properties
Jiulong Li, Qinghao Li, Xiaoqiong Ma, Bing Tian, Tao Li, Jiangliu Yu, Shang Dai, Yulan Weng & Yuejin Hua
Pages: 5931-5944
Published online: 09 Nov 2016
AbstractforBiosynthesis of gold nanoparticles by the extreme bacterium Deinococcus radiodurans and an evaluation of their antibacterial properties | Full Text | References | PDF (6 MB)
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Article
Intestinal anti-inflammatory effects of RGD-functionalized silk fibroin nanoparticles in trinitrobenzenesulfonic acid-induced experimental colitis in rats
Alba Rodriguez-Nogales, Francesca Algieri, Laura De Matteis, A. Abel Lozano-Perez, Jose Garrido-Mesa, Teresa Vezza, J M. de la Fuente, Jose Luis Cenis, Julio Gálvez & Maria Elena Rodriguez-Cabezas
Pages: 5945-5958
Published online: 10 Nov 2016
AbstractforIntestinal anti-inflammatory effects of RGD-functionalized silk fibroin nanoparticles in trinitrobenzenesulfonic acid-induced experimental colitis in rats | Full Text | References | PDF (1.1 MB)
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Article
Nanomedicine strategy for optimizing delivery to outer hair cells by surface-modified poly(lactic/glycolic acid) nanoparticles with hydrophilic molecules
Xingxing Wen, Shan Ding, Hui Cai, Junyi Wang, Lu Wen, Fan Yang & Gang Chen
Pages: 5959-5969
Published online: 10 Nov 2016
AbstractforNanomedicine strategy for optimizing delivery to outer hair cells by surface-modified poly(lactic/glycolic acid) nanoparticles with hydrophilic molecules | Full Text | References | PDF (3.1 MB)
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Article
Effects of Carbopol® 934 proportion on nanoemulsion gel for topical and transdermal drug delivery: a skin permeation study
Yin Zheng, Wu-Qing Ouyang, Yun-Peng Wei, Shahid Faraz Syed, Chao-Shuang Hao, Bo-Zhen Wang & Yan-Hong Shang
Pages: 5971-5987
Published online: 10 Nov 2016
AbstractforEffects of Carbopol® 934 proportion on nanoemulsion gel for topical and transdermal drug delivery: a skin permeation study | Full Text | References | PDF (5.9 MB)
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Article
Enhancing the specificity of polymerase chain reaction by graphene oxide through surface modification: zwitterionic polymer is superior to other polymers with different charges
Yong Zhong, Lihong Huang, Zhisen Zhang, Yunjing Xiong, Liping Sun & Jian Weng
Pages: 5989-6002
Published online: 11 Nov 2016
AbstractforEnhancing the specificity of polymerase chain reaction by graphene oxide through surface modification: zwitterionic polymer is superior to other polymers with different charges | Full Text | References | PDF (2.3 MB)
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Article
A facile route to form self-carried redox-responsive vorinostat nanodrug for effective solid tumor therapy
Leiqiang Han, Tianqi Wang, Jingliang Wu, Xiaolan Yin, Hao Fang & Na Zhang
Pages: 6003-6022
Published online: 11 Nov 2016
AbstractforA facile route to form self-carried redox-responsive vorinostat nanodrug for effective solid tumor therapy | Full Text | References | PDF (9.8 MB)
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Article
Osseointegration of nanohydroxyapatite- or nano-calcium silicate-incorporated polyetheretherketone bioactive composites in vivo
Rui Ma, Zhifeng Yu, Songchao Tang, Yongkang Pan, Jie Wei & Tingting Tang
Pages: 6023-6033
Published online: 14 Nov 2016
AbstractforOsseointegration of nanohydroxyapatite- or nano-calcium silicate-incorporated polyetheretherketone bioactive composites in vivo | Full Text | References | PDF (4.4 MB)
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Article
Preparation and characterization of novel chitosan–protamine nanoparticles for nucleus-targeted anticancer drug delivery
Xiwei Yu, Jiahui Hou, Yijie Shi, Chang Su & Liang Zhao
Pages: 6035-6046
Published online: 14 Nov 2016
AbstractforPreparation and characterization of novel chitosan–protamine nanoparticles for nucleus-targeted anticancer drug delivery | Full Text | References | PDF (2.8 MB)
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Article
Cationic PEGylated liposomes incorporating an antimicrobial peptide tilapia hepcidin 2–3: an adjuvant of epirubicin to overcome multidrug resistance in cervical cancer cells
Vivian Juang, Hsin-Pin Lee, Anya Maan-Yuh Lin & Yu-Li Lo
Pages: 6047-6064
Published online: 15 Nov 2016
AbstractforCationic PEGylated liposomes incorporating an antimicrobial peptide tilapia hepcidin 2–3: an adjuvant of epirubicin to overcome multidrug resistance in cervical cancer cells | Full Text | References | PDF (3.8 MB)
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Article
Synthesis of three-arm block copolymer poly(lactic-co-glycolic acid)–poly(ethylene glycol) with oxalyl chloride and its application in hydrophobic drug delivery
Xiaowei Zhu, Chao Liu, Jianwei Duan, Xiaoyu Liang, Xuanling Li, Hongfan Sun, Deling Kong & Jing Yang
Pages: 6065-6077
Published online: 28 Feb 2023
AbstractforSynthesis of three-arm block copolymer poly(lactic-co-glycolic acid)–poly(ethylene glycol) with oxalyl chloride and its application in hydrophobic drug delivery | Full Text | References | PDF (1.4 MB)
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Article
Polyethyleneimine-coated quantum dots for miRNA delivery and its enhanced suppression in HepG2 cells
Gaofeng Liang, Yang Li, Wenpo Feng, Xinshuai Wang, Aihua Jing, Jinghua Li & Kaiwang Ma
Pages: 6079-6088
Published online: 15 Nov 2016
AbstractforPolyethyleneimine-coated quantum dots for miRNA delivery and its enhanced suppression in HepG2 cells | Full Text | References | PDF (2.9 MB)
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Article
Nanoparticle-based strategy for personalized B-cell lymphoma therapy
Nicola M Martucci, Nunzia Migliaccio, Immacolata Ruggiero, Francesco Albano, Gaetano Calì, Simona Romano, Monica Terracciano, Ilaria Rea, Paolo Arcari & Annalisa Lamberti
Pages: 6089-6101
Published online: 16 Nov 2016
AbstractforNanoparticle-based strategy for personalized B-cell lymphoma therapy | Full Text | References | PDF (2.2 MB)
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Article
Improved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine
Bo Li, Michael Siuta, Vanessa Bright, Dmitry Koktysh, Brittany K Matlock, Megan E Dumas, Meiying Zhu, Alex Holt, Donald Stec, Shenglou Deng, Paul B Savage, Sebastian Joyce & Wellington Pham
Pages: 6103-6121
Published online: 16 Nov 2016
AbstractforImproved proliferation of antigen-specific cytolytic T lymphocytes using a multimodal nanovaccine | Full Text | References | PDF (3.9 MB)
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Article
The effect of dexamethasone/cell-penetrating peptide nanoparticles on gene delivery for inner ear therapy
Ji Young Yoon, Keum-Jin Yang, Shi-Nae Park, Dong-Kee Kim & Jong-Duk Kim
Pages: 6123-6134
Published online: 16 Nov 2016
AbstractforThe effect of dexamethasone/cell-penetrating peptide nanoparticles on gene delivery for inner ear therapy | Full Text | References | PDF (3 MB)
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Article
Celastrol nanomicelles attenuate cytokine secretion in macrophages and inhibit macrophage-induced corneal neovascularization in rats
Zhanrong Li, Jingguo Li, Lei Zhu, Ying Zhang, Junjie Zhang, Lin Yao, Dan Liang & Liya Wang
Pages: 6135-6148
Published online: 18 Nov 2016
AbstractforCelastrol nanomicelles attenuate cytokine secretion in macrophages and inhibit macrophage-induced corneal neovascularization in rats | Full Text | References | PDF (2.9 MB)
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Article
Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles
Paula Zaman, Julia Wang, Adam Blau, Weiping Wang, Tina Li, Daniel S Kohane, Joseph Loscalzo & Ying-Yi Zhang
Pages: 6149-6159
Published online: 18 Nov 2016
AbstractforIncorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles | Full Text | References | PDF (892.1 KB)
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Article
Pegylated and nanoparticle-conjugated sulfonium salt photo triggers necrotic cell death
Alaa A Fadhel, Xiling Yue, Ebrahim H Ghazvini Zadeh, Mykhailo V Bondar & Kevin D Belfield
Pages: 6161-6168
Published online: 18 Nov 2016
AbstractforPegylated and nanoparticle-conjugated sulfonium salt photo triggers necrotic cell death | Full Text | References | PDF (2.4 MB)
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Article
Monte Carlo simulations guided by imaging to predict the in vitro ranking of radiosensitizing nanoparticles
Paul Retif, Aurélie Reinhard, Héna Paquot, Valérie Jouan-Hureaux, Alicia Chateau, Lucie Sancey, Muriel Barberi-Heyob, Sophie Pinel & Thierry Bastogne
Pages: 6169-6179
Published online: 18 Nov 2016
AbstractforMonte Carlo simulations guided by imaging to predict the in vitro ranking of radiosensitizing nanoparticles | Full Text | References | PDF (7.9 MB)
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Article
Fabrication and characterization of drug-loaded nano-hydroxyapatite/polyamide 66 scaffolds modified with carbon nanotubes and silk fibroin
Meng-Zhu Yao, Ming-Yi Huang-Fu, Hui-Na Liu, Xia-Rong Wang, Xiaoxia Sheng & Jian-Qing Gao
Pages: 6181-6194
Published online: 18 Nov 2016
AbstractforFabrication and characterization of drug-loaded nano-hydroxyapatite/polyamide 66 scaffolds modified with carbon nanotubes and silk fibroin | Full Text | References | PDF (3.1 MB)
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Article
In vitro inflammatory effects of hard metal (WC–Co) nanoparticle exposure
Andrea L Armstead & Bingyun Li
Pages: 6195-6206
Published online: 21 Nov 2016
AbstractforIn vitro inflammatory effects of hard metal (WC–Co) nanoparticle exposure | Full Text | References | PDF (1.9 MB)
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Article
Pharmacokinetics and safety of DTS-108, a human oligopeptide bound to SN-38 with an esterase-sensitive cross-linker in patients with advanced malignancies: a Phase I study
Romain Coriat, Sandrine J Faivre, Olivier Mir, Chantal Dreyer, Stanislas Ropert, Mohammed Bouattour, Robert Desjardins, François Goldwasser & Eric Raymond
Pages: 6207-6216
Published online: 21 Nov 2016
AbstractforPharmacokinetics and safety of DTS-108, a human oligopeptide bound to SN-38 with an esterase-sensitive cross-linker in patients with advanced malignancies: a Phase I study | Full Text | References | PDF (623.7 KB)
  • 74 Views
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Article
Macrophages participate in local and systemic inflammation induced by amorphous silica nanoparticles through intratracheal instillation
Man Yang, Li Jing, Ji Wang, Yang Yu, Lige Cao, Lianshuang Zhang, Xianqing Zhou & Zhiwei Sun
Pages: 6217-6228
Published online: 28 Feb 2023
AbstractforMacrophages participate in local and systemic inflammation induced by amorphous silica nanoparticles through intratracheal instillation | Full Text | References | PDF (8.7 MB)
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Article
Synthetic high-density lipoproteins for delivery of 10-hydroxycamptothecin
Yue Yuan, Jian Wen, Jie Tang, Qiming Kan, Rose Ackermann, Karl Olsen & Anna Schwendeman
Pages: 6229-6238
Published online: 28 Feb 2023
AbstractforSynthetic high-density lipoproteins for delivery of 10-hydroxycamptothecin | Full Text | References | PDF (1.3 MB)
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Article
Blockage of both the extrinsic and intrinsic pathways of diazinon-induced apoptosis in PaTu cells by magnesium oxide and selenium nanoparticles
Mahdi Shiri, Mona Navaei-Nigjeh, Maryam Baeeri, Mahban Rahimifard, Hossein Mahboudi, Ahmad Reza Shahverdi, Abbas Kebriaeezadeh & Mohammad Abdollahi
Pages: 6239-6250
Published online: 22 Nov 2016
AbstractforBlockage of both the extrinsic and intrinsic pathways of diazinon-induced apoptosis in PaTu cells by magnesium oxide and selenium nanoparticles | Full Text | References | PDF (1.1 MB)
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Article
In vitro evaluation of folic acid-conjugated redox-responsive mesoporous silica nanoparticles for the delivery of cisplatin
Merlis P Alvarez-Berríos & Juan L Vivero-Escoto
Pages: 6251-6265
Published online: 28 Feb 2023
AbstractforIn vitro evaluation of folic acid-conjugated redox-responsive mesoporous silica nanoparticles for the delivery of cisplatin | Full Text | References | PDF (1.9 MB)
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Article
The effect of magnetic nanoparticles on neuronal differentiation of induced pluripotent stem cell-derived neural precursors
Klára Jiráková, Monika Šeneklová, Daniel Jirák, Karolína Turnovcová, Magda Vosmanská, Michal Babič, Daniel Horák, Pavel Veverka & Pavla Jendelová
Pages: 6267-6281
Published online: 24 Nov 2016
AbstractforThe effect of magnetic nanoparticles on neuronal differentiation of induced pluripotent stem cell-derived neural precursors | Full Text | References | PDF (4.2 MB)
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Article
Effect of inserted spacer in hepatic cell-penetrating multifunctional peptide component on the DNA intracellular delivery of quaternary complexes based on modular design
Luchen Zhang, Zhenbo Li, Fangli Sun, Yuhong Xu & Zixiu Du
Pages: 6283-6295
Published online: 24 Nov 2016
AbstractforEffect of inserted spacer in hepatic cell-penetrating multifunctional peptide component on the DNA intracellular delivery of quaternary complexes based on modular design | Full Text | References | PDF (2.9 MB)
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Review

Review Article
The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome
MI Sierra, A Valdés, AF Fernández, R Torrecillas & MF Fraga
Pages: 6297-6306
Published online: 28 Feb 2023
AbstractforThe effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome | Full Text | References | PDF (693.4 KB)
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Original Research

Article
Study of a new bone-targeting titanium implant–bone interface
Xiangning Liu, Ye Zhang, Shaobing Li, Yayu Wang, Ting Sun, Zejian Li, Lizhao Cai, Xiaogang Wang, Lei Zhou & Renfa Lai
Pages: 6307-6324
Published online: 25 Nov 2016
AbstractforStudy of a new bone-targeting titanium implant–bone interface | Full Text | References | PDF (6.2 MB)
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Article
Hydrothermal synthesis of nitrogen-doped carbon dots with real-time live-cell imaging and blood–brain barrier penetration capabilities
Shousi Lu, Shanshan Guo, Pingxiang Xu, Xiaorong Li, Yuming Zhao, Wei Gu & Ming Xue
Pages: 6325-6336
Published online: 28 Nov 2016
AbstractforHydrothermal synthesis of nitrogen-doped carbon dots with real-time live-cell imaging and blood–brain barrier penetration capabilities | Full Text | References | PDF (3 MB)
  • 268 Views
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Article
Preparation and antitumor evaluation of self-assembling oleanolic acid-loaded Pluronic P105/d-α-tocopheryl polyethylene glycol succinate mixed micelles for non-small-cell lung cancer treatment
Hao Wu, Qingxiang Zhong, Rongling Zhong, Houcai Huang, Zhi Xia, Zhongcheng Ke, Zhenhai Zhang, Jie Song & Xiaobin Jia
Pages: 6337-6352
Published online: 28 Nov 2016
AbstractforPreparation and antitumor evaluation of self-assembling oleanolic acid-loaded Pluronic P105/d-α-tocopheryl polyethylene glycol succinate mixed micelles for non-small-cell lung cancer treatment | Full Text | References | PDF (6.8 MB)
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Article
The role of the intestinal microvasculature in inflammatory bowel disease: studies with a modified Caco-2 model including endothelial cells resembling the intestinal barrier in vitro
Jennifer Y Kasper, Maria Iris Hermanns, Christian Cavelius, Annette Kraegeloh, Thomas Jung, Rolf Danzebrink, Ronald E Unger & Charles James Kirkpatrick
Pages: 6353-6364
Published online: 07 Dec 2016
AbstractforThe role of the intestinal microvasculature in inflammatory bowel disease: studies with a modified Caco-2 model including endothelial cells resembling the intestinal barrier in vitro | Full Text | References | PDF (2.9 MB)
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Article
Sustained-release liquisolid compact tablets containing artemether–lumefantrine as alternate-day regimen for malaria treatment to improve patient compliance
Petra Obioma Nnamani, Agatha Adaora Ugwu, Emmanuel Chinedu Ibezim, Franklin Chimaobi Kenechukwu, Paul Achile Akpa, John-Dike Nwabueze Ogbonna, Nicholas Chinedu Obitte, Amelia Ngozi Odo, Maike Windbergs, Claus-Michael Lehr & Anthony Amaechi Attama
Pages: 6365-6378
Published online: 28 Feb 2023
AbstractforSustained-release liquisolid compact tablets containing artemether–lumefantrine as alternate-day regimen for malaria treatment to improve patient compliance | Full Text | References | PDF (2.5 MB)
  • 124 Views
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Article
Multiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluation
Rudra Pangeni, Sang Won Choi, Ok-Cheol Jeon, Youngro Byun & Jin Woo Park
Pages: 6379-6399
Published online: 30 Nov 2016
AbstractforMultiple nanoemulsion system for an oral combinational delivery of oxaliplatin and 5-fluorouracil: preparation and in vivo evaluation | Full Text | References | PDF (2.5 MB)
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Article
Upregulation of Akt/NF-κB-regulated inflammation and Akt/Bad-related apoptosis signaling pathway involved in hepatic carcinoma process: suppression by carnosic acid nanoparticle
Bo Tang, Fang Tang, Zhenran Wang, Guangying Qi, Xingsi Liang, Bo Li, Shengguang Yuan, Jie Liu, Shuiping Yu & Songqing He
Pages: 6401-6420
Published online: 28 Feb 2023
AbstractforUpregulation of Akt/NF-κB-regulated inflammation and Akt/Bad-related apoptosis signaling pathway involved in hepatic carcinoma process: suppression by carnosic acid nanoparticle | Full Text | References | PDF (7.9 MB)
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Review

Review Article
Nanotoxicity: emerging concerns regarding nanomaterial safety and occupational hard metal (WC-Co) nanoparticle exposure
Andrea L Armstead & Bingyun Li
Pages: 6421-6433
Published online: 01 Dec 2016
AbstractforNanotoxicity: emerging concerns regarding nanomaterial safety and occupational hard metal (WC-Co) nanoparticle exposure | Full Text | References | PDF (777 KB)
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Original Research

Article
Synergistic locoregional chemoradiotherapy using a composite liposome-in-gel system as an injectable drug depot
Shruti GuhaSarkar, Kamal Pathak, Niyati Sudhalkar, Prachi More, Jayant Sastri Goda, Vikram Gota & Rinti Banerjee
Pages: 6435-6448
Published online: 28 Feb 2023
AbstractforSynergistic locoregional chemoradiotherapy using a composite liposome-in-gel system as an injectable drug depot | Full Text | References | PDF (2.1 MB)
  • 96 Views
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Article
Systemic delivery and activation of the TRAIL gene in lungs, with magnetic nanoparticles of chitosan controlled by an external magnetic field
Cynthia A Alvizo-Baez, Itza E Luna-Cruz, Natalia Vilches-Cisneros, Cristina Rodríguez-Padilla & Juan M Alcocer-González
Pages: 6449-6458
Published online: 02 Dec 2016
AbstractforSystemic delivery and activation of the TRAIL gene in lungs, with magnetic nanoparticles of chitosan controlled by an external magnetic field | Full Text | References | PDF (1.9 MB)
  • 106 Views
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Article
Biocompatibility and antibacterial activity of nitrogen-doped titanium dioxide nanoparticles for use in dental resin formulations
Andrew Zane, Ranfang Zuo, Frederick A Villamena, Antal Rockenbauer, Ann Marie Digeorge Foushee, Kristin Flores, Prabir K Dutta & Amber Nagy
Pages: 6459-6470
Published online: 05 Dec 2016
AbstractforBiocompatibility and antibacterial activity of nitrogen-doped titanium dioxide nanoparticles for use in dental resin formulations | Full Text | References | PDF (1.5 MB)
  • 139 Views
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Article
Polycaprolactone nanofibrous mesh reduces foreign body reaction and induces adipose flap expansion in tissue engineering chamber
Lin Luo, Yunfan He, Qiang Chang, Gan Xie, Weiqing Zhan, Xuecen Wang, Tao Zhou, Malcolm Xing & Feng Lu
Pages: 6471-6483
Published online: 05 Dec 2016
AbstractforPolycaprolactone nanofibrous mesh reduces foreign body reaction and induces adipose flap expansion in tissue engineering chamber | Full Text | References | PDF (4.9 MB)
  • 73 Views
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Article
Using hyaluronic acid-functionalized pH stimuli-responsive mesoporous silica nanoparticles for targeted delivery to CD44-overexpressing cancer cells
Zhihui Wang, Yongfeng Tian, Hua Zhang, Yanmei Qin, Dong Li, Li Gan & Fanhong Wu
Pages: 6485-6497
Published online: 05 Dec 2016
AbstractforUsing hyaluronic acid-functionalized pH stimuli-responsive mesoporous silica nanoparticles for targeted delivery to CD44-overexpressing cancer cells | Full Text | References | PDF (6 MB)
  • 131 Views
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Article
Reduced Staphylococcus aureus biofilm formation in the presence of chitosan-coated iron oxide nanoparticles
Si-feng Shi, Jing-fu Jia, Xiao-kui Guo, Ya-ping Zhao, De-sheng Chen, Yong-yuan Guo & Xian-long Zhang
Pages: 6499-6506
Published online: 07 Dec 2016
AbstractforReduced Staphylococcus aureus biofilm formation in the presence of chitosan-coated iron oxide nanoparticles | Full Text | References | PDF (1.5 MB)
  • 191 Views
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Article
Biomechanical and histological evaluation of the osseointegration capacity of two types of zirconia implant
Jian-min Han, Guang Hong, Hong Lin, Yoshinaka Shimizu, Yuhan Wu, Gang Zheng, Hongyu Zhang & Keiichi Sasaki
Pages: 6507-6516
Published online: 07 Dec 2016
AbstractforBiomechanical and histological evaluation of the osseointegration capacity of two types of zirconia implant | Full Text | References | PDF (6.2 MB)
  • 107 Views
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Article
PEG-b-PCL polymeric nano-micelle inhibits vascular angiogenesis by activating p53-dependent apoptosis in zebrafish
Tian Zhou, Qinglei Dong, Yang Shen, Wei Wu, Haide Wu, Xianglin Luo, Xiaoling Liao & Guixue Wang
Pages: 6517-6531
Published online: 05 Dec 2016
AbstractforPEG-b-PCL polymeric nano-micelle inhibits vascular angiogenesis by activating p53-dependent apoptosis in zebrafish | Full Text | References | PDF (4 MB)
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Article
Nanomechanical measurement of adhesion and migration of leukemia cells with phorbol 12-myristate 13-acetate treatment
Zhuo Long Zhou, Jing Ma, Ming-Hui Tong, Barbara Pui Chan, Alice Sze Tsai Wong & Alfonso Hing Wan Ngan
Pages: 6533-6545
Published online: 07 Dec 2016
AbstractforNanomechanical measurement of adhesion and migration of leukemia cells with phorbol 12-myristate 13-acetate treatment | Full Text | References | PDF (4.3 MB)
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Article
Intranasal delivery of rotigotine to the brain with lactoferrin-modified PEG-PLGA nanoparticles for Parkinson’s disease treatment
Chenchen Bi, Aiping Wang, Yongchao Chu, Sha Liu, Hongjie Mu, Wanhui Liu, Zimei Wu, Kaoxiang Sun & Youxin Li
Pages: 6547-6559
Published online: 07 Dec 2016
AbstractforIntranasal delivery of rotigotine to the brain with lactoferrin-modified PEG-PLGA nanoparticles for Parkinson’s disease treatment | Full Text | References | PDF (4.3 MB)
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Article
New silver nanoparticles induce apoptosis-like process in E. coli and interfere with mammalian copper metabolism
Iurii A Orlov, Tatiana P Sankova, Polina S Babich, Ilya M Sosnin, Ekaterina Yu Ilyechova, Demid A Kirilenko, Pavel N Brunkov, Gennadii L Ataev, Alexey E Romanov & Ludmila V Puchkova
Pages: 6561-6574
Published online: 15 Dec 2016
AbstractforNew silver nanoparticles induce apoptosis-like process in E. coli and interfere with mammalian copper metabolism | Full Text | References | PDF (2.9 MB)
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The nasal delivery of nanoencapsulated statins – an approach for brain delivery
Adryana Clementino, Mellissa Batger, Gabriela Garrastazu, Michele Pozzoli, Elena Del Favero, Valeria Rondelli, Bianca Gutfilen, Thiago Barboza, Maria B Sukkar, Sergio A L Souza, Laura Cantù & Fabio Sonvico
Pages: 6575-6590
Published online: 28 Feb 2023
AbstractforThe nasal delivery of nanoencapsulated statins – an approach for brain delivery | Full Text | References | PDF (2.4 MB)
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Stimuli-responsive hybrid nanocarriers developed by controllable integration of hyperbranched PEI with mesoporous silica nanoparticles for sustained intracellular siRNA delivery
Neeraj Prabhakar, Jixi Zhang, Diti Desai, Eudald Casals, Tina Gulin-Sarfraz, Tuomas Näreoja, Jukka Westermarck & Jessica M Rosenholm
Pages: 6591-6608
Published online: 08 Dec 2016
AbstractforStimuli-responsive hybrid nanocarriers developed by controllable integration of hyperbranched PEI with mesoporous silica nanoparticles for sustained intracellular siRNA delivery | Full Text | References | PDF (6.3 MB)
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Article
Biophysical evaluation of aminoclay as an effective protectant for protein stabilization during freeze-drying and storage
Jae Geun Song, Sang Hoon Lee & Hyo-Kyung Han
Pages: 6609-6619
Published online: 28 Feb 2023
AbstractforBiophysical evaluation of aminoclay as an effective protectant for protein stabilization during freeze-drying and storage | Full Text | References | PDF (2.1 MB)
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Coalescence of functional gold and monodisperse silver nanoparticles mediated by black Panax ginseng Meyer root extract
Dandan Wang, Josua Markus, Yeon-Ju Kim, Chao Wang, Zuly Elizabeth Jiménez Pérez, Sungeun Ahn, Verónica Castro Aceituno, Ramya Mathiyalagan & Deok Chun Yang
Pages: 6621-6634
Published online: 08 Dec 2016
AbstractforCoalescence of functional gold and monodisperse silver nanoparticles mediated by black Panax ginseng Meyer root extract | Full Text | References | PDF (5.3 MB)
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Biofabrication of a novel biomolecule-assisted reduced graphene oxide: an excellent biocompatible nanomaterial
Xi-Feng Zhang & Sangiliyandi Gurunathan
Pages: 6635-6649
Published online: 08 Dec 2016
AbstractforBiofabrication of a novel biomolecule-assisted reduced graphene oxide: an excellent biocompatible nanomaterial | Full Text | References | PDF (1.5 MB)
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Novel guanidinylated bioresponsive poly(amidoamine)s designed for short hairpin RNA delivery
Jiankun Yu, Jinmin Zhang, Haonan Xing, Yanping Sun, Zhen Yang, Tianzhi Yang, Cuifang Cai, Xiaoyun Zhao, Li Yang & Pingtian Ding
Pages: 6651-6666
Published online: 08 Dec 2016
AbstractforNovel guanidinylated bioresponsive poly(amidoamine)s designed for short hairpin RNA delivery | Full Text | References | PDF (3.5 MB)
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A novel double-targeted nondrug delivery system for targeting cancer stem cells
Shupei Qiao, Yufang Zhao, Shuai Geng, Yong Li, Xiaolu Hou, Yi Liu, Feng-Huei Lin, Lifen Yao & Weiming Tian
Pages: 6667-6678
Published online: 08 Dec 2016
AbstractforA novel double-targeted nondrug delivery system for targeting cancer stem cells | Full Text | References | PDF (3.7 MB)
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Article
Silver nanoparticles inhibit the function of hypoxia-inducible factor-1 and target genes: insight into the cytotoxicity and antiangiogenesis
Tieshan Yang, Qian Yao, Fei Cao, Qianqian Liu, Binlei Liu & Xiu-Hong Wang
Pages: 6679-6692
Published online: 08 Dec 2016
AbstractforSilver nanoparticles inhibit the function of hypoxia-inducible factor-1 and target genes: insight into the cytotoxicity and antiangiogenesis | Full Text | References | PDF (2.6 MB)
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Polyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis
Yinghua Li, Min Guo, Zhengfang Lin, Mingqi Zhao, Misi Xiao, Changbing Wang, Tiantian Xu, Tianfeng Chen & Bing Zhu
Pages: 6693-6702
Published online: 08 Dec 2016
AbstractforPolyethylenimine-functionalized silver nanoparticle-based co-delivery of paclitaxel to induce HepG2 cell apoptosis | Full Text | References | PDF (3 MB)
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Evaluation of β-cyclodextrin-modified gemini surfactant-based delivery systems in melanoma models
Deborah Michel, Waleed Mohammed-Saeid, Heather Getson, Caitlin Roy, Masoomeh Poorghorban, Jackson M Chitanda, Ronald Verrall & Ildiko Badea
Pages: 6703-6712
Published online: 12 Dec 2016
AbstractforEvaluation of β-cyclodextrin-modified gemini surfactant-based delivery systems in melanoma models | Full Text | References | PDF (841.9 KB)
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MicroRNA-200c delivered by solid lipid nanoparticles enhances the effect of paclitaxel on breast cancer stem cell
Jingwen Liu, Tingting Meng, Ming Yuan, Lijuan Wen, Bolin Cheng, Na Liu, Xuan Huang, Yun Hong, Hong Yuan & Fuqiang Hu
Pages: 6713-6725
Published online: 12 Dec 2016
AbstractforMicroRNA-200c delivered by solid lipid nanoparticles enhances the effect of paclitaxel on breast cancer stem cell | Full Text | References | PDF (3.9 MB)
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Manipulation of Schwann cell migration across the astrocyte boundary by polysialyltransferase-loaded superparamagnetic nanoparticles under magnetic field
Bing Xia, Liangliang Huang, Lei Zhu, Zhongyang Liu, Teng Ma, Shu Zhu, Jinghui Huang & Zhuojing Luo
Pages: 6727-6741
Published online: 12 Dec 2016
AbstractforManipulation of Schwann cell migration across the astrocyte boundary by polysialyltransferase-loaded superparamagnetic nanoparticles under magnetic field | Full Text | References | PDF (17.6 MB)
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A novel hydrodynamic approach of drag-reducing polymers to improve left ventricular hypertrophy and aortic remodeling in spontaneously hypertensive rats
Xinlu Zhang, Xu Wang, Feng Hu, Boda Zhou, Hai-Bin Chen, Daogang Zha, Yili Liu, Yansong Guo, Lemin Zheng & Jiancheng Xiu
Pages: 6743-6751
Published online: 13 Dec 2016
AbstractforA novel hydrodynamic approach of drag-reducing polymers to improve left ventricular hypertrophy and aortic remodeling in spontaneously hypertensive rats | Full Text | References | PDF (9.7 MB)
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A polyethylenimine-modified carboxyl-poly(styrene/acrylamide) copolymer nanosphere for co-delivering of CpG and TGF-β receptor I inhibitor with remarkable additive tumor regression effect against liver cancer in mice
Shuyan Liang, Jun Hu, Yuanyuan Xie, Qing Zhou, Yanhong Zhu & Xiangliang Yang
Pages: 6753-6762
Published online: 13 Dec 2016
AbstractforA polyethylenimine-modified carboxyl-poly(styrene/acrylamide) copolymer nanosphere for co-delivering of CpG and TGF-β receptor I inhibitor with remarkable additive tumor regression effect against liver cancer in mice | Full Text | References | PDF (4.8 MB)
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Coating with spermine-pullulan polymer enhances adenoviral transduction of mesenchymal stem cells
Li Wan, Xinglei Yao, Francesco Faiola, Bojun Liu, Tianyuan Zhang, Yasuhiko Tabata, Hiroyuki Mizuguchi, Shinsaku Nakagawa, Jian-Qing Gao & Robert Chunhua Zhao
Pages: 6763-6769
Published online: 13 Dec 2016
AbstractforCoating with spermine-pullulan polymer enhances adenoviral transduction of mesenchymal stem cells | Full Text | References | PDF (1.3 MB)
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Nanoscaled hydrated antimony (V) oxide as a new approach to first-line antileishmanial drugs
Antonia MR Franco, Iryna Grafova, Fabiane V Soares, Gennaro Gentile, Claudia DC Wyrepkowski, Marcos A Bolson, Ézio Sargentini Jr, Cosimo Carfagna, Markku Leskelä & Andriy Grafov
Pages: 6771-6780
Published online: 13 Dec 2016
AbstractforNanoscaled hydrated antimony (V) oxide as a new approach to first-line antileishmanial drugs | Full Text | References | PDF (2.1 MB)
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Novel antimicrobial peptide–modified azithromycin-loaded liposomes against methicillin-resistant Staphylococcus aureus
Xiaowei Liu, Zhan Li, Xiaodong Wang, Yujuan Chen, Fengbo Wu, Ke Men, Ting Xu, Yan Luo & Li Yang
Pages: 6781-6794
Published online: 14 Dec 2016
AbstractforNovel antimicrobial peptide–modified azithromycin-loaded liposomes against methicillin-resistant Staphylococcus aureus | Full Text | References | PDF (4.5 MB)
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Rehmannia glutinosa polysaccharide liposome as a novel strategy for stimulating an efficient immune response and their effects on dendritic cells
Yee Huang, Tao Qin, Yifan Huang, Zhenguang Liu, Ruonan Bo, Yuanliang Hu, Jiaguo Liu, Yi Wu & Deyun Wang
Pages: 6795-6808
Published online: 28 Feb 2023
AbstractforRehmannia glutinosa polysaccharide liposome as a novel strategy for stimulating an efficient immune response and their effects on dendritic cells | Full Text | References | PDF (3.8 MB)
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Rescuing cholinergic neurons from apoptotic degeneration by targeting of serotonin modulator-and apolipoprotein E-conjugated liposomes to the hippocampus
Yung-Chih Kuo & Yin-Jung Lee
Pages: 6809-6824
Published online: 15 Dec 2016
AbstractforRescuing cholinergic neurons from apoptotic degeneration by targeting of serotonin modulator-and apolipoprotein E-conjugated liposomes to the hippocampus | Full Text | References | PDF (1.8 MB)
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