Remote magnetic targeting of iron oxide nanoparticles for cardiovascular diagnosis and therapeutic drug delivery: where are we now?

References

• American College of Cardiology Foundation Task Force on Expert Consensus Documents; HundleyWGBluemkeDAFinnJPACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: a report of the American College of Cardiology Foundation Task Force on Expert Consensus DocumentsJ Am Coll Cardiol201055232614266220513610
   PubMed Web of Science ®Google Scholar
• BoyerCWhittakerMRBulmusVLiuJQDavisTPThe design and utility of polymer-stabilized iron-oxide nanoparticles for nanomedicine applicationsNPG Asia Mater201022330
   Web of Science ®Google Scholar
• AlamSRShahASRichardsJUltrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experienceCirc Cardiovasc Imaging20125555956522875883
   PubMed Web of Science ®Google Scholar
• YilmazADenglerMAvan der KuipHImaging of myocardial infarction using ultrasmall superparamagnetic iron oxide nanoparticles: a human study using a multi-parametric cardiovascular magnetic resonance imaging approachEur Heart J201334646247523103659
   PubMed Web of Science ®Google Scholar
• TangTYHowarthSPMillerSRThe ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study. Evaluation using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging in carotid diseaseJ Am Coll Cardiol200953222039205019477353
   PubMed Web of Science ®Google Scholar
• KrishnanKMBiomedical nanomagnetics: a spin through possibilities in imaging, diagnostics, and therapyIEEE Trans Magn20104672523255820930943
   PubMed Web of Science ®Google Scholar
• StrijkersGJNicolayKRelaxivity of nanoparticles for magnetic resonance imagingSattlerKDHandbook of Nanophysics: Nanomedicine and NanoroboticsBoca Raton, FL, USACRC Press2010
   Google Scholar
• NacevABeniCBrunoOShapiroBThe behaviors of ferro-magnetic nanoparticles in and around blood vessels under applied magnetic fieldsJ Magn Magn Mater201132365166821278859
   PubMed Web of Science ®Google Scholar
• PankhurstQAConnollyJJonesSKDobsonJApplications of magnetic nanoparticles in biomedicineJ Phys D Appl Phys20033613167181
   Web of Science ®Google Scholar
• LubbeASBergemannCRiessHClinical experiences with magnetic drug targeting: a phase I study with 4′-epidoxorubicin in 14 patients with advanced solid tumorsCancer Res19965620468646938840985
   PubMed Web of Science ®Google Scholar
• ChengKShenDHensleyMTMagnetic antibody-linked nanomatchmakers for therapeutic cell targetingNat Commun20145488025205020
   PubMedGoogle Scholar
• PankhurstQAThanhNTKJonesSKDobsonJProgress in applications of magnetic nanoparticles in biomedicineJ Phys D Appl Phys20094222224001
   Web of Science ®Google Scholar
• ConnellJJPatrickPSYuYLythgoeMFKalberTLAdvanced cell therapies: targeting, tracking and actuation of cells with magnetic particlesRegen Med201510675777226390317
   PubMedGoogle Scholar
• LaurentSDutzSHäfeliUOMahmoudiMMagnetic fluid hyperthermia: focus on superparamagnetic iron oxide nanoparticlesAdv Colloid Interface Sci20111661–282321601820
   PubMed Web of Science ®Google Scholar
• KolhatkarAGJamisonACLitvinovDWillsonRCLeeTRTuning the magnetic properties of nanoparticlesInt J Mol Sci2013148159771600923912237
   PubMed Web of Science ®Google Scholar
• LuAHSalabasELSchüthFMagnetic nanoparticles: synthesis, protection, functionalization, and applicationAngew Chem Int Ed Engl20074681222124417278160
   PubMed Web of Science ®Google Scholar
• LaurentSSaeiAABehzadiSPanahifarAMahmoudiMSuperparamagnetic iron oxide nanoparticles for delivery of therapeutic agents: opportunities and challengesExpert Opin Drug Deliv20141191449147024870351
   PubMed Web of Science ®Google Scholar
• RoohiFLohrkeJIdeASchutzGDasslerKStudying the effect of particle size and coating type on the blood kinetics of superparamagnetic iron oxide nanoparticlesInt J Nanomedicine201274447445822927759
   PubMed Web of Science ®Google Scholar
• TsourkasAJosephsonLMagnetic nanoparticlesWeisslederRMolecular Imaging: Principles and Practice1st edShelton, CT, USAPMPH-USA2010523541
   Google Scholar
• WeisslederRNahrendorfMPittetMJImaging macrophages with nanoparticlesNat Mater20141312513824452356
   PubMed Web of Science ®Google Scholar
• GuptaAKGuptaMSynthesis and surface engineering of iron oxide nanoparticles for biomedical applicationsBiomaterials200526183995402115626447
   PubMed Web of Science ®Google Scholar
• ThorekDLTsourkasASize, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cellsBiomaterials200829263583359018533252
   PubMed Web of Science ®Google Scholar
• ChampionJAMitragotriSRole of target geometry in phagocytosisProc Natl Acad Sci U S A2006103134930493416549762
   PubMed Web of Science ®Google Scholar
• DoshiNMitragotriSDesigner biomaterials for nanomedicineAdv Funct Mater2009192438433854
   Web of Science ®Google Scholar
• AnselmoACZhangMKumarSElasticity of nanoparticles influences their blood circulation, phagocytosis, endocytosis, and targetingACS Nano2015933169317725715979
   PubMed Web of Science ®Google Scholar
• MitragotriSLahannJPhysical approaches to biomaterial designNat Mater200981152319096389
   PubMed Web of Science ®Google Scholar
• HillaireauHCouvreurPNanocarriers’ entry into the cell: relevance to drug deliveryCell Mol Life Sci200966172873289619499185
   PubMed Web of Science ®Google Scholar
• DemolisPLaslopAMelchiorriDRuizSSancho-LopezACHMP assessment report: RiensoEMA/CHMP59684192012
   Google Scholar
• ReimerPBalzerTFerucarbotran (Resovist): a new clinically approved RES-specific contrast agent for contrast-enhanced MRI of the liver: properties, clinical development, and applicationsEur Radiol20031361266127612764641
   PubMed Web of Science ®Google Scholar
• WangAZNanoparticles for cancer diagnosis and therapyWebsterTJSafety of Nanoparticles: From Manufacturing to Medical ApplicationsNew York, USASpringer2008209236
   Google Scholar
• MiltenyiSMullerWWeichelWRadbruchAHigh gradient magnetic cell separation with MACSCytometry19901122312381690625
   PubMedGoogle Scholar
• AlexiouCDiehlDHenningerPA high field gradient magnet for magnetic drug targetingIEEE Trans Appl Supercond200616215271530
   Web of Science ®Google Scholar
• SarwarANemirovskiAShapiroBOptimal halbach permanent magnet designs for maximally pulling and pushing nanoparticlesJ Magn Magn Mater2012324574275423335834
   PubMed Web of Science ®Google Scholar
• PolyakBFishbeinIChornyMHigh field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stentsProc Natl Acad Sci U S A2008105269870318182491
   PubMed Web of Science ®Google Scholar
• FuAWilsonRJSmithBRFluorescent magnetic nanoparticles for magnetically enhanced cancer imaging and targeting in living subjectsACS Nano2012686862686922857784
   PubMedGoogle Scholar
• RieglerJWellsJAKyrtatosPGPriceANPankhurstQALythgoeMFTargeted magnetic delivery and tracking of cells using a magnetic resonance imaging systemBiomaterials201031105366537120382425
   PubMedGoogle Scholar
• VoltairasPAFotiadisDIMichalisLKHydrodynamics of magnetic drug targetingJ Biomech200235681382112021001
   PubMed Web of Science ®Google Scholar
• ShenYLiuXHuangZComparison of magnetic intensities for mesenchymal stem cell targeting therapy on ischemic myocardial repair: high magnetic intensity improves cell retention but has no additional functional benefitCell Transplant201524101981199725375750
   PubMedGoogle Scholar
• WuWWuZYuTJiangCKimWSRecent progress on magnetic iron oxide nanoparticles: synthesis, surface functional strategies and biomedical applicationsSci Tech Adv Mater201516223501
   PubMed Web of Science ®Google Scholar
• FiguerolaADiCRMannaLPellegrinoTFrom iron oxide nanoparticles towards advanced iron-based inorganic materials designed for biomedical applicationsPharmacol Res201062212614320044004
   PubMedGoogle Scholar
• HindsKAHillJMShapiroEMHighly efficient endosomal labeling of progenitor and stem cells with large magnetic particles allows magnetic resonance imaging of single cellsBlood2003102386787212676779
   PubMed Web of Science ®Google Scholar
• StrobelKHoerrVSchmidFWachsmuthLLofflerBFaberCEarly detection of lung inflammation: exploiting T1-effects of iron oxide particles using UTE MRIMagn Reson Med20126861924193122368111
   PubMedGoogle Scholar
• HoerrVTuchscherrLHuveJBacteria tracking by in vivo magnetic resonance imagingBMC Biol2013116323714179
   PubMedGoogle Scholar
• ShapiroBKulkarniSNacevAMuroSStepanovPYWeinbergINOpen challenges in magnetic drug targetingWiley Interdiscip Rev Nanomed Nanobiotechnol20157344645725377422
   PubMed Web of Science ®Google Scholar
• KimRJAlbertTSWibleJHPerformance of delayed-enhancement magnetic resonance imaging with gadoversetamide contrast for the detection and assessment of myocardial infarction: an international, multicenter, double-blinded, randomized trialCirculation2008117562963718212288
   PubMed Web of Science ®Google Scholar
• ErsoyHRybickiFJBiochemical safety profiles of gadolinium-based extracellular contrast agents and nephrogenic systemic fibrosisJ Magn Reson Imaging20072651190119717969161
   PubMed Web of Science ®Google Scholar
• MahrholdtHWagnerAJuddRMSechtemUAssessment of myocardial viability by cardiovascular magnetic resonance imagingEur Heart J200223860261911969275
   PubMedGoogle Scholar
• LuMCohenMHRievesDPazdurRFDA report: ferumoxytol for intravenous iron therapy in adult patients with chronic kidney diseaseAm J Hematol201085531531920201089
   PubMed Web of Science ®Google Scholar
• NeuweltASidhuNHuCAMladyGEberhardtSCSillerudLOIron-based superparamagnetic nanoparticle contrast agents for MRI of infection and inflammationAJR Am J Roentgenol20152043302313
   PubMed Web of Science ®Google Scholar
• RichardsJMSempleSIMacGillivrayTJAbdominal aortic aneurysm growth predicted by uptake of ultrasmall superparamagnetic particles of iron oxide: a pilot studyCirc Cardiovasc Imaging20114327428121304070
   PubMedGoogle Scholar
• SadatUHowarthSPUsmanATangTYGravesMJGillardJHSequential imaging of asymptomatic carotid atheroma using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging: a feasibility studyJ Stroke Cerebrovasc Dis201322827127622100828
   PubMedGoogle Scholar
• HolaKMarkovaZZoppellaroGTucekJZborilRTailored functionalization of iron oxide nanoparticles for MRI, drug delivery, magnetic separation and immobilization of biosubstancesBiotechnol Adv2015336 Pt 21162117625689073
   PubMed Web of Science ®Google Scholar
• VeisehOGunnJWZhangMDesign and fabrication of magnetic nanoparticles for targeted drug delivery and imagingAdv Drug Deliv Rev201062328430419909778
   PubMed Web of Science ®Google Scholar
• SchleichNDanhierFPreatVIron oxide-loaded nanotheranostics: major obstacles to in vivo studies and clinical translationJ Control Release2015198355425481448
   PubMed Web of Science ®Google Scholar
• Quyen ChauNDMenard-MoyonCKostarelosKBiancoAMultifunctional carbon nanomaterial hybrids for magnetic manipulation and targetingBiochem Biophys Res Commun2015468345446226129773
   PubMedGoogle Scholar
• MuraSNicolasJCouvreurPStimuli-responsive nanocarriers for drug deliveryNat Mater20131211991100324150417
   PubMed Web of Science ®Google Scholar
• WilsonWRHayMTargeting hypoxia in cancer therapyNat Rev Cancer201111639341021606941
   PubMed Web of Science ®Google Scholar
• PrabhakarUMaedaHJainRKChallenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncologyCancer Res20137382412241723423979
   PubMed Web of Science ®Google Scholar
• National Institutes of HealthSafety and efficacy of doxorubicin adsorbed to magnetic. Beads vs IV doxorubicin in treating liver cancerClinicalTrials.gov Available from: https://clinicaltrials.gov/ct2/show/NCT00034333Accessed April 25, 20025232005562016
   Google Scholar
• CherryEMEatonJKA comprehensive model of magnetic particle motionduring magnetic drug targetingInt J Multiph Flow201459173185
   Web of Science ®Google Scholar
• HaverkortJKenjeresSKleijnCComputational simulations of magnetic particle capture in arterial flowsAnn Biomed Eng200937122436244819760148
   PubMed Web of Science ®Google Scholar
• RobeyTESaigetMKReineckeHMurryCESystems approaches to preventing transplanted cell death in cardiac repairJ Mol Cell Cardiol200845456758118466917
   PubMed Web of Science ®Google Scholar
• ChengKLiTSMalliarasKDavisDRZhangYMarbanEMagnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarctionCirc Res2010106101570158120378859
   PubMed Web of Science ®Google Scholar
• ChengKMalliarasKLiTSMagnetic enhancement of cell retention, engraftment, and functional benefit after intracoronary delivery of cardiac-derived stem cells in a rat model of ischemia/reperfusionCell Transplant20122161121113522405128
   PubMedGoogle Scholar
• ZhangYLiWOuLTargeted delivery of human VEGF gene via complexes of magnetic nanoparticle-adenoviral vectors enhanced cardiac regenerationPLoS One201277e3949022844395
   PubMed Web of Science ®Google Scholar
• LiWMaNOngLLEnhanced thoracic gene delivery by magnetic nanobead-mediated vectorJ Gene Med200810889790918481827
   PubMedGoogle Scholar
• LiWNesselmannCZhouZGene delivery to the heart by magnetic nanobeadsJ Magn Magn Mater20073111336341
   Google Scholar
• HuangZShenYPeiNThe effect of nonuniform magnetic targeting of intracoronary-delivering mesenchymal stem cells on coronary embolisationBiomaterials201334389905991624055521
   PubMedGoogle Scholar
• HuangZShenYSunAMagnetic targeting enhances retrograde cell retention in a rat model of myocardial infarctionStem Cell Res Ther20134614924330751
   PubMedGoogle Scholar
• VandergriffACHensleyTMHenryETMagnetic targeting of cardiosphere-derived stem cells with ferumoxytol nanoparticles for treating rats with myocardial infarctionBiomaterials201435308528853925043570
   PubMed Web of Science ®Google Scholar
• MoonHParkHEKangJNoninvasive assessment of myocardial inflammation by cardiovascular magnetic resonance in a rat model of experimental autoimmune myocarditisCirculation2012125212603261222550157
   PubMedGoogle Scholar
• ChristenTNahrendorfMWildgruberMMolecular imaging of innate immune cell function in transplant rejectionCirculation2009119141925193219332470
   PubMedGoogle Scholar
• DashRChungJChanTA molecular MRI probe to detect treatment of cardiac apoptosis in vivoMagn Reson Med20116641152116221360750
   PubMedGoogle Scholar
• NacevAKomaeeASarwarATowards control of magnetic fluids in patients: directing therapeutic nanoparticles to disease locationsIEEE Control Syst Mag20123233274
   Web of Science ®Google Scholar
• MuthanaMKennerleyAJHughesRDirecting cell therapy to anatomic target sites in vivo with magnetic resonance targetingNat Commun20156800926284300
   PubMed Web of Science ®Google Scholar
• SetsompopKKimmlingenREberleinEPushing the limits of in vivo diffusion MRI for the Human Connectome ProjectNeuroimage20138022023323707579
   PubMedGoogle Scholar
• RichardsJMShawCALangNNIn vivo mononuclear cell tracking using superparamagnetic particles of iron oxide: feasibility and safety in humansCirc Cardiovasc Imaging20125450951722787016
   PubMed Web of Science ®Google Scholar