Acute and subacute toxicity profiles of thymoquinone-loaded nanostructured lipid carrier in BALB/c mice

References

• Gali-MuhtasibHRoessnerASchneider-StockRThymoquinone: a promising anti-cancer drug from natural sourcesInt J Biochem Cell Biol20063881249125316314136
   PubMed Web of Science ®Google Scholar
• KhaderMBresgenNEcklPMIn vitro toxicological properties of thymoquinoneFood Chem Toxicol200947112913319010375
   PubMed Web of Science ®Google Scholar
• HajhashemiVGhannadiAJafarabadiHBlack cumin seed essential oil, as a potent analgesic and antiinflammatory drugPhytother Res200418319519915103664
   PubMed Web of Science ®Google Scholar
• BuritsMBucarFAntioxidant activity of Nigella sativa essential oilPhytother Res200014532332810925395
   PubMed Web of Science ®Google Scholar
• Gali-MuhtasibHOckerMKuesterDThymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer modelsJ Cell Mol Med200812133034218366456
   PubMedGoogle Scholar
• Ali SalimLZOthmanRAbdullaMAThymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitroPLoS One2014912e11534025531768
   PubMedGoogle Scholar
• Jrah HarzallahHGrayaaRKharoubiWMaaloulAHammamiMMahjoubTThymoquinone, the Nigella sativa bioactive compound, prevents circulatory oxidative stress caused by 1,2-dimethylhydrazine in erythrocyte during colon postinitiation carcinogenesisOxid Med Cell Longev201220126
   Google Scholar
• NgWKSaiful YazanLYapLHWan Nor HafizaWAHowCWAbdullahRThymoquinone-loaded nanostructured lipid carrier exhibited cytotoxicity towards breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines (HeLa and SiHa)Biomed Res Int2015201510
   Web of Science ®Google Scholar
• Schneider-StockRFakhouryIHZakiAMEl-BabaCOGali-MuhtasibHUThymoquinone: fifty years of success in the battle against cancer modelsDrug Discov Today2014191183024001594
   PubMed Web of Science ®Google Scholar
• PathanSAJainGKZaidiSMAStability-indicating ultra-performance liquid chromatography method for the estimation of thymoquinone and its application in biopharmaceutical studiesBiomed Chromatogr201125561362020734352
   PubMed Web of Science ®Google Scholar
• GabizonABradburyMPrabhakarUZamboniWLibuttiSGrodzinskiPCancer nanomedicines: closing the translational gapLancet201438499612175217625625382
   PubMed Web of Science ®Google Scholar
• YuD-GLiX-YWangXYangJ-HBlighSWAWilliamsGRNanofibers fabricated using triaxial electrospinning as zero order drug delivery systemsACS Appl Mater Interfaces2015733188911889726244640
   PubMed Web of Science ®Google Scholar
• HierrezueloJPeláezLBenaventeJManuel JuanL-RRicoRArmengolRBioengineered nanomaterialsTiwariALipid Cyclodext Nanocarriers Loadind Bioact Agents Stab Polym SupportFloridaCRC Press2013226
   Google Scholar
• DehghaniHHashemiMEntezariMMohsenifarAThe comparison of anticancer activity of thymoquinone and nanothymoquinone on human breast adenocarcinomaIran J Pharm Res201514253954625901162
   PubMed Web of Science ®Google Scholar
• YuD-GZhuL-MBranford-WhiteCJSolid dispersions in the form of electrospun core-sheath nanofibersInt J Nanomedicine201163271328022228995
   PubMed Web of Science ®Google Scholar
• RodriguesBVMLeiteNCSCavalcantiBGraphene oxide/multi-walled carbon nanotubes as nanofeatured scaffolds for the assisted deposition of nanohydroxyapatite: characterization and biological evaluationInt J Nanomedicine2016112569258527358560
   PubMed Web of Science ®Google Scholar
• RawatMSinghDSarafSSarafSLipid carriers: a versatile delivery vehicle for proteins and peptidesYakugaku Zasshi2008128226928018239375
   PubMedGoogle Scholar
• KaurIPBhandariRBhandariSKakkarVPotential of solid lipid nanoparticles in brain targetingJ Control Release200812729710918313785
   PubMed Web of Science ®Google Scholar
• LinXLiXZhengLYuLZhangQLiuWPreparation and characterization of monocaprate nanostructured lipid carriersColloids Surf A Physicochem Eng Asp20073111–3106111
   Google Scholar
• ZhangXYQiaoHNiJMShiYBQiangYPreparation of isoliquiritigenin-loaded nanostructured lipid carrier and the in vivo evaluation in tumor-bearing miceEur J Pharm Sci201349341142223624327
   PubMed Web of Science ®Google Scholar
• MaedaHWuJSawaTMatsumuraYHoriKTumor vascular permeability and the EPR effect in macromolecular therapeutics: a reviewJ Control Release2000651–227128410699287
   PubMed Web of Science ®Google Scholar
• BuxtonDBLeeSCWicklineSAFerrariMNational Heart, Lung, and Blood Institute Nanotechnology Working GroupRecommendations of the National Heart, Lung, and Blood Institute Nanotechnology Working GroupCirculation2003108222737274214656908
   PubMedGoogle Scholar
• European Technology Platform on NanomedicineVision Paper and Basis for a Strategic Research Agenda for NanomedicineLuxembourgOfficial Publications of the European Commission200537
   Google Scholar
• FerrariMCancer nanotechnology: opportunities and challengesNat Rev Cancer20055316117115738981
   PubMed Web of Science ®Google Scholar
• YildirimerLThanhNTKLoizidouMSeifalianAMToxicology and clinical potential of nanoparticlesNano Today20116658560723293661
   PubMedGoogle Scholar
• VarshosazJHassanzadehFSadeghiHAndalibSSynthesis of octadecylamine-retinoic acid conjugate for enhanced cytotoxic effects of 5-FU using LDL targeted nanostructured lipid carriersEur J Med Chem20125442943822687440
   PubMed Web of Science ®Google Scholar
• European Union ExecutiveCommission recommendation of 18 October 2011 on the definition of nanomaterialOff J Eur Union2011L2751
   Google Scholar
• PainiMDalySRAliakbarianBAn efficient liposome based method for antioxidants encapsulationColloids Surf B Biointerfaces20151361067107226590900
   PubMed Web of Science ®Google Scholar
• ThatipamulaRPalemCGannuRMudragadaSYamsaniMFormulation and in vitro characterization of domperidone loaded solid lipid nanoparticles and nanostructured lipid carriersDaru2011191233222615636
   PubMed Web of Science ®Google Scholar
• MüllerRHRadtkeMWissingSASolid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparationsAdv Drug Deliv Rev200254suppl 1S131S15512460720
   PubMed Web of Science ®Google Scholar
• MontanerJCano-SarabiaMSimatsACharge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in ratsInt J Nanomedicine2016113035304827418824
   PubMedGoogle Scholar
• El-AnsaryAAl-DaihanSOn the toxicity of therapeutically used nanoparticles: an overviewJ Toxicol2009200975481020130771
   PubMedGoogle Scholar
• OECDTest No. 420: Acute Oral Toxicity – Fixed Dose ProcedureOECD Publishing2001 Available from: https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd_gl420.pdfAccessed June 3, 2016
   Google Scholar
• WangXSuSIhsanAAcute and sub-chronic toxicity study of diaveridine in wistar ratsRegul Toxicol Pharmacol201573123224026209270
   PubMedGoogle Scholar
• OECDTest No. 407: Repeated Dose 28-Day Oral Toxicity Study in RodentsOECD Publishing2008 Available from: http://www.oecd.org/env/test-no-407-repeated-dose-28-day-oral-toxicity-study-in-rodents-9789264070684-en.htmAccessed June 3, 2016
   Google Scholar
• TeoSStirlingDThomasSHobermanAKiorpesAKhetaniVA 90-day oral gavage toxicity study of d-methylphenidate and d,l-methylphenidate in Sprague–Dawley ratsToxicology2002179318319612270592
   PubMed Web of Science ®Google Scholar
• HuXChengSLiuXDevelopment of monoclonal antibodies and immunochromatographic lateral flow device for rapid test of alanine aminotransferase isoenzyme 1Protein Expr Purif20161199410126611609
   PubMedGoogle Scholar
• WangHSitW-HTipoeGLWanJM-FDifferential protective effects of extra virgin olive oil and corn oil in liver injury: a proteomic studyFood Chem Toxicol20147413113825303780
   PubMedGoogle Scholar
• MeertsIATMVerspeek-RipCMBuskensCAFToxicological evaluation of pomegranate seed oilFood Chem Toxicol20094761085109219425183
   PubMed Web of Science ®Google Scholar
• Center for Drug Evaluation and ResearchGuidance for Industry Estimating the Maximum Safe Starting Dose in Initial Clinical Trials for Therapeutics in Adult Healthy VolunteersUS Dep Heal Hum Serv2005127
   Google Scholar