Dissolving Microneedle-Based Cascade-Activation Nanoplatform for Enhanced Photodynamic Therapy of Skin Cancer

References

• Su Y, Lu K, Huang Y, et al. Targeting Warburg effect to rescue the suffocated photodynamic therapy: a cancer-specific solution. Biomaterials. 2023;294:122017. doi:10.1016/j.biomaterials.2023.122017
   PubMed Web of Science ®Google Scholar
• Gong X, Li J, Xu X, et al. Microvesicle-inspired oxygen-delivering nanosystem potentiates radiotherapy-mediated modulation of tumor stroma and antitumor immunity. Biomaterials. 2022;290:121855. doi:10.1016/j.biomaterials.2022.121855
   PubMed Web of Science ®Google Scholar
• Yu H, Cheng Y, Wen C, Sun YQ, Yin XB. Triple cascade nanocatalyst with laser-activatable O(2) supply and photothermal enhancement for effective catalytic therapy against hypoxic tumor. Biomaterials. 2022;280:121308. doi:10.1016/j.biomaterials.2021.121308
   PubMed Web of Science ®Google Scholar
• Zhao Z, Wang W, Li C, et al. Reactive oxygen species–activatable liposomes regulating hypoxic tumor microenvironment for synergistic photo/chemodynamic therapies. Adv Funct Mater. 2019;29(44):1905013. doi:10.1002/adfm.201905013
   Web of Science ®Google Scholar
• Song C, Tang C, Xu W, et al. Hypoxia-targeting multifunctional nanoparticles for sensitized chemotherapy and phototherapy in head and neck squamous cell carcinoma. Int j Nanomed. 2020;15:347–361. doi:10.2147/ijn.S233294
   PubMed Web of Science ®Google Scholar
• Marcu L, Olver I. Tirapazamine: from bench to clinical trials. Curr Clin Pharmacol. 2006;1(1):71–79. doi:10.2174/157488406775268192
   PubMedGoogle Scholar
• Zhang G, Wang W, Zou H, et al. Novel semiconducting nano-agents incorporating tirapazamine for imaging guided synergistic cancer hypoxia activated photo-chemotherapy. J Mat Chem B. 2021;9(26):5318–5328. doi:10.1039/d1tb00659b
   PubMed Web of Science ®Google Scholar
• Knackstedt TJ, Knackstedt RW, Djohan M, Djohan R, Gastman BR, Crowe DR. New developments in the management of cutaneous squamous cell carcinoma. Plast Reconst Surg. 2021;147(3):492–504. doi:10.1097/PRS.0000000000007678
   PubMed Web of Science ®Google Scholar
• Waldman A, Schmults C. Cutaneous squamous cell carcinoma. Hematol Oncol Clin N Am. 2019;33(1):1–12. doi:10.1016/j.hoc.2018.08.001
   PubMed Web of Science ®Google Scholar
• Ji Z, Yang G, Shahzidi S, et al. Induction of hypoxia-inducible factor-1alpha overexpression by cobalt chloride enhances cellular resistance to photodynamic therapy. Cancer Lett. 2006;244(2):182–189. doi:10.1016/j.canlet.2005.12.010
   PubMed Web of Science ®Google Scholar
• Brahimi-Horn MC, Pouysségur J. The hypoxia-inducible factor and tumor progression along the angiogenic pathway. Int Rev Cytol. 2005;242:157–213. doi:10.1016/s0074-7696(04)42004-x
   PubMedGoogle Scholar
• Ratcliffe PJ, O’Rourke JF, Maxwell PH, Pugh CW. Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol. 1998;201(Pt 8):1153–1162. doi:10.1242/jeb.201.8.1153
   PubMed Web of Science ®Google Scholar
• Zhang K, Chen D, Ma K, Wu X, Hao H, Jiang S. NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as a therapeutic and diagnostic target in cancer. J Med Chem. 2018;61(16):6983–7003. doi:10.1021/acs.jmedchem.8b00124
   PubMed Web of Science ®Google Scholar
• Oh ET, Kim JW, Kim JM, Kim SJ, Lee JS. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593. doi:10.1038/ncomms13593
   PubMed Web of Science ®Google Scholar
• Lamberti MJ, Morales Vasconsuelo AB, Chiaramello M, et al. NQO1 induction mediated by photodynamic therapy synergizes with β-Lapachone-halogenated derivative against melanoma. Biomed Pharmacother. 2018;108:1553–1564. doi:10.1016/j.biopha.2018.09.159
   PubMed Web of Science ®Google Scholar
• Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. Ca a Cancer J Clinicians. 2023;73(1):17–48. doi:10.3322/caac.21763
   PubMed Web of Science ®Google Scholar
• Stratigos AJ, Garbe C, Dessinioti C, et al. European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: part 2. Treatment. Eur J Cancer. 2020;128:83–102. doi:10.1016/j.ejca.2020.01.008
   PubMed Web of Science ®Google Scholar
• Migden MR, Rischin D, Schmults CD, et al. PD-1 blockade with cemiplimab in advanced cutaneous squamous-cell carcinoma. New Engl J Med. 2018;379(4):341–351. doi:10.1056/NEJMoa1805131
   PubMed Web of Science ®Google Scholar
• Cullen JK, Simmons JL, Parsons PG, Boyle GM. Topical treatments for skin cancer. Adv Drug Delivery Rev. 2020;153:54–64. doi:10.1016/j.addr.2019.11.002
   PubMed Web of Science ®Google Scholar
• Lalotra AS, Singh V, Khurana B, Agrawal S, Shrestha S, Arora D. A comprehensive review on nanotechnology-based innovations in topical drug delivery for the treatment of skin cancer. Curr Pharm Des. 2020;26(44):5720–5731. doi:10.2174/1381612826666200819202821
   PubMed Web of Science ®Google Scholar
• Yang D, Chen M, Sun Y, et al. Microneedle-mediated transdermal drug delivery for treating diverse skin diseases. Acta Biomater. 2021;121:119–133. doi:10.1016/j.actbio.2020.12.004
   PubMed Web of Science ®Google Scholar
• Menon GK, Cleary GW, Lane ME. The structure and function of the stratum corneum. Int J Pharm. 2012;435(1):3–9. doi:10.1016/j.ijpharm.2012.06.005
   PubMed Web of Science ®Google Scholar
• Lopes LB, Garcia MT, Bentley MV. Chemical penetration enhancers. Ther Deliv. 2015;6(9):1053–1061. doi:10.4155/tde.15.61
   PubMedGoogle Scholar
• Ita K. Perspectives on transdermal electroporation. Pharmaceutics. 2016;8(1):9.
   PubMed Web of Science ®Google Scholar
• Wang Y, Thakur R, Fan Q, Michniak B. Transdermal iontophoresis: combination strategies to improve transdermal iontophoretic drug delivery. Eur J Pharm Biopharm. 2005;60(2):179–191. doi:10.1016/j.ejpb.2004.12.008
   PubMed Web of Science ®Google Scholar
• Pawar KR, Babu RJ. Lipid materials for topical and transdermal delivery of nanoemulsions. Crit Rev Ther Drug Carrier Syst. 2014;31(5):429–458. doi:10.1615/critrevtherdrugcarriersyst.2014010663
   PubMed Web of Science ®Google Scholar
• Wani TU, Mohi-Ud-Din R, Majeed A, Kawoosa S, Pottoo FH. Skin permeation of nanoparticles: mechanisms involved and critical factors governing topical drug delivery. Curr Pharm Des. 2020;26(36):4601–4614. doi:10.2174/1381612826666200701204010
   PubMed Web of Science ®Google Scholar
• Au SH. Dissolving microneedle vaccination—no magic needled. Sci Trans Med. 2018;10(460):eaav0343.
   Google Scholar
• Lamberti MJ, Vittar NB, da Silva Fde C, Ferreira VF, Rivarola VA. Synergistic enhancement of antitumor effect of β-Lapachone by photodynamic induction of quinone oxidoreductase (NQO1). Phytomedicine. 2013;20(11):1007–1012. doi:10.1016/j.phymed.2013.04.018
   PubMed Web of Science ®Google Scholar
• Serpe L, Ellena S, Barbero N, et al. Squaraines bearing halogenated moieties as anticancer photosensitizers: synthesis, characterization and biological evaluation. Eur J Med Chem. 2016;113:187–197. doi:10.1016/j.ejmech.2016.02.035
   PubMed Web of Science ®Google Scholar
• Dinkova-Kostova AT, Talalay P. Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen. Free Radic Biol Med. 2000;29(3–4):231–240. doi:10.1016/s0891-5849(00)00300-2
   PubMed Web of Science ®Google Scholar